Strain-specific polyketide synthase genes of Aspergillus niger

International Journal of Food Microbiology

Volumn 155, Issue 3, 2012, Pages 137-145

  Ferracin, Lara Munique ^a   Fier, Carla Beatriz ^a   Vieira, Maria Lucia Carneiro ^b   Monteiro Vitorello, Claudia Barros ^b   Varani, Alessandro de Mello ^b   Rossi, Maria Magdalena ^b   Müller Santos, Marcelo ^c   Taniwaki, Marta Hiromi ^d   Thie Iamanaka, Beatriz ^d   Fungaro, Maria Helena Pelegrinelli ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^d INSTITUTO DE TECNOLOGIA DE ALIMENTOS   (Brazil)

Author keywords

Aspergillus niger; Mycotoxin; Ochratoxin; Secondary metabolites; Strain specific polyketide synthase

Indexed keywords

OCHRATOXIN; POLYKETIDE SYNTHASE;

ARTICLE; ASPERGILLUS NIGER; BIOINFORMATICS; COMPUTER MODEL; FUNGAL GENE; FUNGAL STRAIN; GENE AMPLIFICATION; GENE CLUSTER; GENE SEQUENCE; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

ASPERGILLUS NIGER; COMPUTATIONAL BIOLOGY; DNA, FUNGAL; GENES, FUNGAL; GENETIC VARIATION; MULTIGENE FAMILY; OCHRATOXINS; POLYKETIDE SYNTHASES; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

ASPERGILLUS NIGER;

EID: 84859210642     PISSN: 01681605     EISSN: 18793460     Source Type: Journal    
DOI: 10.1016/j.ijfoodmicro.2012.01.020     Document Type: Article

References (35)

1. Abarca M.L., Bragulat M.R., Castellá G., Cabañes F.J. Ochratoxin A production by strains of Aspergillus niger var. niger. Applied and Environmental Microbiology 1994, 60:2650-2652.
2. Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.I., Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K., Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z., van Dijck P.W.M., Hofmann G., Lasure L.L., Magnuson J.K., Menke H., Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.J., Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M., Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y., Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P., Martinez D., van Peij N.N.M.E., Roubos J.A., Nielsen J., Baker S.E. Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88. Genome Research 2011, 21:885-897.
3. Azevedo A.C.S., Furlaneto M.C., Souza-Gomes D.R., Fungaro M.H.P. Molecular characterization of Paecilomyces fumoroseus (Deuteromycotina Hyphomycetes) isolates. Scientia Agricola 2000, 57:729-732.
4. Bacha N., Atoui A., Mathieu F., Liboz T., Lebrihi A. Aspergillus westerdijkiae polyketide synthase gene "aoks1" is involved in the biosynthesis of ochratoxin A. Fungal Genetics and Biology 2009, 46:77-84.
5. Castellá G., Cabanes F.J. Development of a Real Time PCR system for detection of ochratoxin A-producing strains of the Aspergillus niger aggregate. Food Control 2011, 22:1367-1372.
6. Dao H.P., Mathieu F., Lebrihi A. Two primer pairs to detect OTA producers by PCR method. International Journal of Food Microbiology 2005, 104:61-67.
7. El Khoury A., Atoui A. Ochratoxin A: general overview and actual molecular status. Toxins 2010, 2:461-493.
8. Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Liggett-Fraser C.M., Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., Jiang B., Denning D.W., Nierman W.C. Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus. PLoS Genetics 2008, 4:e1000046. 10.1371/journal.pgen.1000046.
9. Fedorova N.D., Nierman W.C. Comparative genomics of Aspergillus. Aspergillus: molecular biology and genomics 2010, 41-60. Caister Academic Press, Norfolk. M. Machida, K. Gomi (Eds.).
10. Filtenborg O., Frisvald J.C., Svendensen J.A. Simple screening method for molds producing intracellular mycotoxins in pure cultures. Applied and Environmental Microbiology 1983, 45:581-585.
11. Fisch K.M., Gillaspy A.F., Gipson M., Henrikson J.C., Hoover A.R., Jackson L., Najar F.Z., Wägele H., Cichewicz R.H. Chemical induction of silent biosynthetic pathway transcription in Aspergillus niger. Journal of Industrial Microbiology and Biotechnology 2009, 36:1199-1213.
12. 2 production by Aspergillus niger. Journal of Agricultural and Food Chemistry 2007, 55:9727-9732.
13. Gallo A., Perrone G., Solfrizzo M., Epifani F., Abbas A., Dobson A.D.W., Mulè G. Characterisation of a pks gene which is expressed during ochratoxin A production by Aspergillus carbonarius. International Journal of Food Microbiology 2009, 129:8-15.
14. Gautam A.K., Sharma S.A., Bhadauria R. Diversity, pathogenicity and toxicology of A. niger: an important spoilage fungi. Research Journal of Microbiology 2011, 6:270-280.
15. Glass N.L., Donaldson G.C. Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes. Applied and Environmental Microbiology 1995, 61:1323-1330.
16. Huffman J., Gerber R., Du L. Recent advancements in the biosynthetic mechanisms for polyketide-derived mycotoxins. Biopolymers 2010, 93:764-766.
17. IARC (International Agency for Research on Cancer) Ochratoxin A. In: monographs on the evaluation of carcinogenic risks to humans, 56. Some naturally occurring substances: food items and constituents. Heterocyclic Aromatic Amines and Mycotoxins 1993, 489-521. International Agency for Research on Cancer, Lyon.
18. Karolewiez A., Geisen R. Cloning a part of the ochratoxin A biosynthetic gene cluster of Penicillium nordicum and characterization of the ochratoxin polyketide synthase gene. Systematic and Applied Microbiology 2005, 28:588-595.
19. O'Callaghan J., Caddick M.X., Dobson A.D.W. A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus. Microbiology 2003, 149:3485-3491.
20. O'Callaghan J., Stapleton P.C., Dobson A.D.W. Ochratoxin A biosynthetic genes in Aspergillus ochraceus are differentially regulated by pH and nutritional stimuli. Fungal Genetics and Biology 2006, 43:213-221.
21. Pontecorvo G., Roper J.A., Hemmons L.M., MaCDonald K.D., Bufton A.W.J. The genetics of Aspergillus nidulans. Advances in Genetics 1953, 5:141-148.
22. Palmer J.M., Keller N.P. Secondary metabolism in fungi: does chromosomal location matter?. Current Opinion in Microbiology 2010, 13:431-436.
23. Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J., Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J., d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P., van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U., Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P., van Ooyen A.J., Visser J., Stam H. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Nature Biotechnology 2007, 25:221-231.
24. Rokas A., Payne G., Fedorova N.D., Baker S.E., Machida M., Yu J., Ryan Georgiana D., Dean R.A., Bhatnagar D., Cleveland T.E., Wortman J.R., Maiti R., Joardar V., Amedeo P., Denning D.W., Nierman W.C. What can comparative genomics tell us about species concepts in the genus Aspergillus?. Studies in Mycology 2007, 59:11-17.
25. Sambrook J., Russell D.W. Molecular cloning: A laboratory manual 2001, Cold Spring Harbour Laboratory Press, New York. third ed.
26. Samson R.A., Houbraken J.A.M.P., Kuijpers A.F.A., Frank J.M., Frisvad J.C. New ochratoxin A or sclerotium producing species in Aspergillus section Nigri. Studies in Mycology 2004, 50:45-61.
27. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of Sciences of the USA 1977, 74:5463-5467.
28. Sun J., Lu X., Rinas U., Zeng A.P. Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics. Genome Biology 2007, 8:R182.
29. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods. Molecular Biology and Evolution 2011, 28:2731-2739.
30. Taniwaki M.H., Pitt J.I., Teixeira A.A., Iamanaka B.T. The source of ochratoxin A in Brazilian coffee and its formation in relation to processing methods. International Journal of Food Microbiology 2003, 82:173-179.
31. Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Research 1994, 22:4673-4680.
32. Turner G. Genomics and Secondary Metabolism in Aspergillus. Aspergillus: Molecular Biology and Genomics 2010, 139-155. Caister Academic Press, Norfolk. M. Machida, K. Gomi (Eds.).
33. van der Merwe K.J., Steyn P.S., Fourie L., Scott D.B., Theron J.J. Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus Wilh. Nature 1965, 205:1112-1113.
34. Vargas E.A., Santos E.A., Pittet A. Determination of ochratoxin A in green coffee by immunoaffinity column cleanup and liquid chromatography collaborative study. Journal of AOAC International 2005, 88:773-779.
35. von Döhren H. A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans. Fungal Genetics and Biology 2009, 46:S45-S52.