Cytotoxic Salan-Titanium(IV) Complexes: High Activity Toward a Range of Sensitive and Drug-Resistant Cell Lines, and Mechanistic Insights

ChemMedChem

Volumn 7, Issue 4, 2012, Pages 703-708

  Manna, Cesar M ^a   Braitbard, Ori ^a   Weiss, Esther ^a   Hochman, Jacob ^a   Tshuva, Edit Y ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Antitumor agents; Apoptosis; Cisplatin; Cytotoxicity; Titanium(IV)

Indexed keywords

CISPLATIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN P53; TITANIUM DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; BONE MARROW; BREAST; BREAST CANCER; CANCER CELL CULTURE; CANCER RESISTANCE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL VIABILITY; COLON; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STABILITY; FLOW CYTOMETRY; HEART; HUMAN; HUMAN CELL; HYDROLYSIS; IC 50; KIDNEY; LEUKEMIA; LIVER; LUNG; NONHUMAN; OVARY; PANCREAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; SPLEEN; UPREGULATION; UTERINE CERVIX;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CISPLATIN; COORDINATION COMPLEXES; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG STABILITY; FEMALE; HUMANS; MICE; OVARIAN NEOPLASMS; TITANIUM;

EID: 84859201412     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100593     Document Type: Article

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