Phenotyping vs. genotyping for prediction of clopidogrel efficacy and safety: The PEGASUS-PCI study

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 4, 2012, Pages 529-542

  Siller Matula, J M ^a   Delle Karth, G ^a   Lang, I M ^a   Neunteufl, T ^a   Kozinski, M ^b   Kubica, J ^b   Maurer, G ^a   Linkowska, K ^b   Grzybowski, T ^b   Huber, K ^c   Jilma, B ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^c WILHELMINEN HOSPITAL   (Austria)

Author keywords

Clopidogrel; CYP2C19; Major bleeding; MEA; Platelets; Polymorphism; Sensitivity; Specificity; Stent thrombosis

Indexed keywords

CLOPIDOGREL; CYTOCHROME P450 2C19; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ADULT; ALLELE; ARTICLE; BLEEDING; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DNA POLYMORPHISM; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; GENETIC ANALYSIS; GENOTYPE; HEART DEATH; HUMAN; ISCHEMIA; MAJOR CLINICAL STUDY; MALE; MULTIPLE ELECTRODE AGGREGOMETRY; PERCUTANEOUS CORONARY INTERVENTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; STENT THROMBOSIS; SURVIVAL RATE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; TREATMENT RESPONSE;

AGED; ANGIOPLASTY, BALLOON, CORONARY; ARYL HYDROCARBON HYDROXYLASES; AUSTRIA; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; CELL ADHESION MOLECULES; CHI-SQUARE DISTRIBUTION; CORONARY ARTERY DISEASE; FEMALE; GENE FREQUENCY; GENOTYPE; HEMORRHAGE; HUMANS; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHARMACOGENETICS; PHENOTYPE; PHOSPHOPROTEINS; PHOSPHORYLATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SENSITIVITY AND SPECIFICITY; THROMBOSIS; TICLOPIDINE; TIME FACTORS; TREATMENT OUTCOME;

EID: 84859181019     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04639.x     Document Type: Article

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