메뉴 건너뛰기




Volumn 8, Issue 12, 2010, Pages 2624-2641

Effect of proton pump inhibitors on clinical outcome in patients treated with clopidogrel: A systematic review and meta-analysis

Author keywords

Clopidogrel; Death; Gastrointestinal bleeding; Major adverse cardiac events; Myocardial infarction; Proton pump inhibitor; Stent thrombosis

Indexed keywords

CLOPIDOGREL; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR;

EID: 78349244351     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.04049.x     Document Type: Article
Times cited : (138)

References (62)
  • 2
    • 54349121974 scopus 로고    scopus 로고
    • Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
    • Siller-Matula JM, Lang I, Christ G, Jilma B. Calcium-channel blockers reduce the antiplatelet effect of clopidogrel. J Am Coll Cardiol 2008; 52: 1557-63.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1557-1563
    • Siller-Matula, J.M.1    Lang, I.2    Christ, G.3    Jilma, B.4
  • 5
    • 76549094772 scopus 로고    scopus 로고
    • Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular disease
    • Siller-Matula JM, Krumphuber J, Jilma B. Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular disease. Br J Pharmacol 2009; 159: 502-17.
    • (2009) Br J Pharmacol , vol.159 , pp. 502-517
    • Siller-Matula, J.M.1    Krumphuber, J.2    Jilma, B.3
  • 6
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC, Le Gal G, Lacut K, Le Calvez G, Mansourati J, Mottier D, Abgrall JF, Boschat J. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008; 51: 256-60.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3    Le Gal, G.4    Lacut, K.5    Le Calvez, G.6    Mansourati, J.7    Mottier, D.8    Abgrall, J.F.9    Boschat, J.10
  • 13
    • 78650002192 scopus 로고    scopus 로고
    • A National Study of the Effect of Individual Proton Pump Inhibitors on Cardiovascular Outcomes in Patients Treated with Clopidogrel Following Coronary Stenting: The Clopidogrel Medco Outcomes Study. presented at SCAI, Las Vegas 2009:Abstract O-11.
    • Stanek EJ, Aubert R, Flockhart D, Kreutz RP, Yao J, Breall J, Desta Z, Skaar T, Frueh F, Teagarden J, Epstein R. A National Study of the Effect of Individual Proton Pump Inhibitors on Cardiovascular Outcomes in Patients Treated with Clopidogrel Following Coronary Stenting: The Clopidogrel Medco Outcomes Study. presented at SCAI, Las Vegas 2009:Abstract O-11.
    • Stanek, E.J.1    Aubert, R.2    Flockhart, D.3    Kreutz, R.P.4    Yao, J.5    Breall, J.6    Desta, Z.7    Skaar, T.8    Frueh, F.9    Teagarden, J.10    Epstein, R.11
  • 14
    • 61549124132 scopus 로고    scopus 로고
    • Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
    • Ho PM, Maddox TM, Wang L, Fihn SD, Jesse RL, Peterson ED, Rumsfeld JS. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009; 301: 937-44.
    • (2009) JAMA , vol.301 , pp. 937-944
    • Ho, P.M.1    Maddox, T.M.2    Wang, L.3    Fihn, S.D.4    Jesse, R.L.5    Peterson, E.D.6    Rumsfeld, J.S.7
  • 15
    • 77953911134 scopus 로고    scopus 로고
    • Higher stent thrombosis rate after coronary stenting in patients on dual antiplatelet treatment and concomitant treatment with proton pump inhibitors
    • ;: Abstract 894.
    • Sarafoff N, Sibbing D, Sonntag U, Schulz S, Schoemig A, Kastrati A. Higher stent thrombosis rate after coronary stenting in patients on dual antiplatelet treatment and concomitant treatment with proton pump inhibitors. Eur Heart J 2009; 30(Suppl.): P150. Abstract 894.
    • (2009) Eur Heart J , vol.30 , Issue.SUPPL.
    • Sarafoff, N.1    Sibbing, D.2    Sonntag, U.3    Schulz, S.4    Schoemig, A.5    Kastrati, A.6
  • 16
    • 77950641429 scopus 로고    scopus 로고
    • Proton pump inhibitors increase the risk of major adverse cardiovascular events in post-PCI patients who are on clopidogrel
    • ;: Abstract P653.
    • Banerjee S, Varghese C, Weideman R, Weideman M, Little BB. Proton pump inhibitors increase the risk of major adverse cardiovascular events in post-PCI patients who are on clopidogrel. Eur Heart J 2009; 30(Suppl.): P92. Abstract P653.
    • (2009) Eur Heart J , vol.30 , Issue.SUPPL.
    • Banerjee, S.1    Varghese, C.2    Weideman, R.3    Weideman, M.4    Little, B.B.5
  • 17
    • 51049115517 scopus 로고    scopus 로고
    • Initial assessment of clinical impact of a drug interaction between clopidogrel and proton pump inhibitors
    • Pezalla E, Day D, Pulliadath I. Initial assessment of clinical impact of a drug interaction between clopidogrel and proton pump inhibitors. J Am Coll Cardiol 2008; 52: 1038-9.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1038-1039
    • Pezalla, E.1    Day, D.2    Pulliadath, I.3
  • 18
    • 77956392178 scopus 로고    scopus 로고
    • Effects of proton-pump inhibitors on outcome of patients discharged on dual-antiplatelet therapy after percutaneous coronary intervention and stent implantation
    • ; :P98. Abstract P675.
    • Jarai R, Brosovic I, Tentzeris I, Farhan S, Unger G, Huber K. Effects of proton-pump inhibitors on outcome of patients discharged on dual-antiplatelet therapy after percutaneous coronary intervention and stent implantation. Eur Heart J 2009; (Suppl. 30):P98. Abstract P675.
    • (2009) Eur Heart J , Issue.SUPPL.. 30
    • Jarai, R.1    Brosovic, I.2    Tentzeris, I.3    Farhan, S.4    Unger, G.5    Huber, K.6
  • 19
    • 78649995051 scopus 로고    scopus 로고
    • Proton pump inhibitor and clopidogrel combination is not associated with adverse clinical outcomes after PCI: The NHLBI Dynamic Registry. American College of Cardiology Session/i2 Summit 2009; A27: 2903-7.
    • Ramirez JF, Selzer F, Chakaprani R, Anderson WD, Lee JS, Smith C, Mulukutla RS, Kip KE, Kelsey SF, Marroquin OC. Proton pump inhibitor and clopidogrel combination is not associated with adverse clinical outcomes after PCI: The NHLBI Dynamic Registry. American College of Cardiology Session/i2 Summit 2009; A27: 2903-7.
    • Ramirez, J.F.1    Selzer, F.2    Chakaprani, R.3    Anderson, W.D.4    Lee, J.S.5    Smith, C.6    Mulukutla, R.S.7    Kip, K.E.8    Kelsey, S.F.9    Marroquin, O.C.10
  • 20
  • 22
    • 78649749402 scopus 로고    scopus 로고
    • Proton Pump inhibitors and clopidogrel response on cardiovascular major events in patients after acute myocardial infarction. Data from the FAST-MI registry of the french society of cardiology
    • Simon T, Quandalle PH, Machecourt J, Sader R, Ledain L, Bataille V, Brunel PH, Djiane P, Julliard JM, Danchin N. Proton Pump inhibitors and clopidogrel response on cardiovascular major events in patients after acute myocardial infarction. Data from the FAST-MI registry of the french society of cardiology. Eur Heart J 2009; 30(Suppl.): P2121.
    • (2009) Eur Heart J , vol.30 , Issue.SUPPL.
    • Simon, T.1    Quandalle, P.H.2    Machecourt, J.3    Sader, R.4    Ledain, L.5    Bataille, V.6    Brunel, P.H.7    Djiane, P.8    Julliard, J.M.9    Danchin, N.10
  • 23
    • 78649998716 scopus 로고    scopus 로고
    • COGENT: A Prospective, Randomized,Placebo-Controlled Trial of Omeprazole in Patients Receiving Aspirin and Clopidogrel. presented at TCT 2009 San Francisco 2009:; Accessed 8 October 2009.
    • Bhatt DL. COGENT: A Prospective, Randomized, Placebo-Controlled Trial of Omeprazole in Patients Receiving Aspirin and Clopidogrel. presented at TCT 2009 San Francisco 2009:; Accessed 8 October 2009.
    • Bhatt, D.L.1
  • 25
    • 31644436390 scopus 로고    scopus 로고
    • Compliance with QUOROM and quality of reporting of overlapping meta-analyses on the role of acetylcysteine in the prevention of contrast associated nephropathy: case study
    • Biondi-Zoccai GG, Lotrionte M, Abbate A, Testa L, Remigi E, Burzotta F, Valgimigli M, Romagnoli E, Crea F, Agostoni P. Compliance with QUOROM and quality of reporting of overlapping meta-analyses on the role of acetylcysteine in the prevention of contrast associated nephropathy: case study. BMJ 2006; 332: 202-9.
    • (2006) BMJ , vol.332 , pp. 202-209
    • Biondi-Zoccai, G.G.1    Lotrionte, M.2    Abbate, A.3    Testa, L.4    Remigi, E.5    Burzotta, F.6    Valgimigli, M.7    Romagnoli, E.8    Crea, F.9    Agostoni, P.10
  • 29
    • 77954396061 scopus 로고    scopus 로고
    • Risk of adverse clinical outcomes with concomitant use of clopidogrel and proton pump inhibitors following percutaneous coronary intervention
    • Gupta E, Bansal D, Sotos J, Olden K. Risk of adverse clinical outcomes with concomitant use of clopidogrel and proton pump inhibitors following percutaneous coronary intervention. Dig Dis Sci 2010; 55: 1964-8.
    • (2010) Dig Dis Sci , vol.55 , pp. 1964-1968
    • Gupta, E.1    Bansal, D.2    Sotos, J.3    Olden, K.4
  • 30
    • 73449122247 scopus 로고    scopus 로고
    • Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome
    • Rassen JA, Choudhry NK, Avorn J, Schneeweiss S. Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome. Circulation 2009; 120: 2322-9.
    • (2009) Circulation , vol.120 , pp. 2322-2329
    • Rassen, J.A.1    Choudhry, N.K.2    Avorn, J.3    Schneeweiss, S.4
  • 31
    • 77949670945 scopus 로고    scopus 로고
    • Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction
    • Evanchan J, Donnally MR, Binkley P, Mazzaferri E. Recurrence of acute myocardial infarction in patients discharged on clopidogrel and a proton pump inhibitor after stent placement for acute myocardial infarction. Clin Cardiol 2010; 33: 168-71.
    • (2010) Clin Cardiol , vol.33 , pp. 168-171
    • Evanchan, J.1    Donnally, M.R.2    Binkley, P.3    Mazzaferri, E.4
  • 34
    • 77949665264 scopus 로고    scopus 로고
    • Mortality associated with proton pump inhibitors following percutaneous coronary interventions with drug eluting stents
    • Sweeny JM, Kini A, Muntner P, Jakkula M, Farkouh M, Sharma S. Mortality associated with proton pump inhibitors following percutaneous coronary interventions with drug eluting stents. Circulation 2009; 120: S936.
    • (2009) Circulation , vol.120
    • Sweeny, J.M.1    Kini, A.2    Muntner, P.3    Jakkula, M.4    Farkouh, M.5    Sharma, S.6
  • 35
    • 77949725700 scopus 로고    scopus 로고
    • Does proton pump inhibitor use following percutaneous coronary intervention with drug-eluting stents impact clinical outcome?
    • Torguson R, Chou C, Kaneshige K, Xue Z, Satler L, Kent K, Pichard A, Suddath W, Waksman R. Does proton pump inhibitor use following percutaneous coronary intervention with drug-eluting stents impact clinical outcome? Circulation 2009; 120: S968.
    • (2009) Circulation , vol.120
    • Torguson, R.1    Chou, C.2    Kaneshige, K.3    Xue, Z.4    Satler, L.5    Kent, K.6    Pichard, A.7    Suddath, W.8    Waksman, R.9
  • 37
    • 78649992758 scopus 로고    scopus 로고
    • Six-Month Outcomes with or without Proton-Pump Inhibitors after Successful PCI: Insights from the Guthrie PCI Registry. ACC 2010:A2903-07.
    • Harjai JK, Shenoy C, Orshaw P, Boura J, Rogers G Six-Month Outcomes with or without Proton-Pump Inhibitors after Successful PCI: Insights from the Guthrie PCI Registry. ACC 2010:A2903-07.
    • Harjai, J.K.1    Shenoy, C.2    Orshaw, P.3    Boura, J.4    Rogers, G.5
  • 38
    • 78649994741 scopus 로고    scopus 로고
    • Proton Pump Inhibitors are Associated with Cardiovascular Risk Independent of Clopidogrel Use in Patients with Myocardial Infarction: A Nationwide Propensity Score Matched Study. ACC 2010; A1100-273.
    • Charlot MG, Ahlehoff O, Jorgensen CH, Abildstrom SZ, Køber L, Hansen PR, Torp-Pedersen C, Gislason G. Proton Pump Inhibitors are Associated with Cardiovascular Risk Independent of Clopidogrel Use in Patients with Myocardial Infarction: A Nationwide Propensity Score Matched Study. ACC 2010; A1100-273.
    • Charlot, M.G.1    Ahlehoff, O.2    Jorgensen, C.H.3    Abildstrom, S.Z.4    Køber, L.5    Hansen, P.R.6    Torp-Pedersen, C.7    Gislason, G.8
  • 39
    • 78649994192 scopus 로고    scopus 로고
    • Pharmacodynamic Effects and Clinical Outcomes of Clopidogrel and Ticlopidine with or without a Proton-pump Inhibitor. ACC 2010 Atlanta A:1021-110.
    • Oshima S, Noda K, Fukushima H, Nakamura S, Taniguchi I, Kugimiya F, Higa K, Nishijima T, Hanatani S. Pharmacodynamic Effects and Clinical Outcomes of Clopidogrel and Ticlopidine with or without a Proton-pump Inhibitor. ACC 2010 Atlanta A:1021-110.
    • Oshima, S.1    Noda, K.2    Fukushima, H.3    Nakamura, S.4    Taniguchi, I.5    Kugimiya, F.6    Higa, K.7    Nishijima, T.8    Hanatani, S.9
  • 43
    • 77949770788 scopus 로고    scopus 로고
    • Proton pump inhibitors increase major adverse cardiac events among post percutaneous coronary intervention patients on clopidogrel
    • Ching G, Li D, McKay R, Mather J, Lundbye J. Proton pump inhibitors increase major adverse cardiac events among post percutaneous coronary intervention patients on clopidogrel. Circulation 2009; 120: S936-7.
    • (2009) Circulation , vol.120
    • Ching, G.1    Li, D.2    McKay, R.3    Mather, J.4    Lundbye, J.5
  • 44
    • 78649984594 scopus 로고    scopus 로고
    • Clinical outcomes following coronary stenting in Japanese patients with and without proton pump inhibitor. ACC 2010; A:1074-99.
    • Shimomura H, Hokimoto S, Ogawa H, Investigators TK. Clinical outcomes following coronary stenting in Japanese patients with and without proton pump inhibitor. ACC 2010; A:1074-99.
    • Shimomura, H.1    Hokimoto, S.2    Ogawa, H.3    Investigators, T.K.4
  • 45
    • 41849094074 scopus 로고    scopus 로고
    • Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome
    • Ng FH, Wong SY, Lam KF, Chang CM, Lau YK, Chu WM, Wong BC. Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome. Am J Gastroenterol 2008; 103: 865-71.
    • (2008) Am J Gastroenterol , vol.103 , pp. 865-871
    • Ng, F.H.1    Wong, S.Y.2    Lam, K.F.3    Chang, C.M.4    Lau, Y.K.5    Chu, W.M.6    Wong, B.C.7
  • 46
    • 77949690349 scopus 로고    scopus 로고
    • Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel
    • Kwok CS, Loke YK. Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel. Aliment Pharmacol Ther 2010; 31: 810-23.
    • (2010) Aliment Pharmacol Ther , vol.31 , pp. 810-823
    • Kwok, C.S.1    Loke, Y.K.2
  • 47
    • 77953896604 scopus 로고    scopus 로고
    • Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis
    • Hulot JS, Collet JP, Silvain J, Pena A, Bellemain-Appaix A, Barthelemy O, Cayla G, Beygui F, Montalescot G. Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis. J Am Coll Cardiol 2010; 56: 134-43.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 134-143
    • Hulot, J.S.1    Collet, J.P.2    Silvain, J.3    Pena, A.4    Bellemain-Appaix, A.5    Barthelemy, O.6    Cayla, G.7    Beygui, F.8    Montalescot, G.9
  • 48
    • 69249132034 scopus 로고    scopus 로고
    • Both in- and out-hospital worsening of renal function predict outcome in patients with heart failure: results from the Coordinating Study Evaluating Outcome of Advising and Counseling in Heart Failure (COACH)
    • Damman K, Jaarsma T, Voors AA, Navis G, Hillege HL, Van Veldhuisen DJ. Both in- and out-hospital worsening of renal function predict outcome in patients with heart failure: results from the Coordinating Study Evaluating Outcome of Advising and Counseling in Heart Failure (COACH). Eur J Heart Fail 2009; 11: 847-54.
    • (2009) Eur J Heart Fail , vol.11 , pp. 847-854
    • Damman, K.1    Jaarsma, T.2    Voors, A.A.3    Navis, G.4    Hillege, H.L.5    Van Veldhuisen, D.J.6
  • 51
    • 60949083948 scopus 로고    scopus 로고
    • Platelet reactivity after clopidogrel treatment assessed with point-of-care analysis and early drug-eluting stent thrombosis
    • Sibbing D, Braun S, Morath T, Mehilli J, Vogt W, Schomig A, Kastrati A, Von Beckerath N. Platelet reactivity after clopidogrel treatment assessed with point-of-care analysis and early drug-eluting stent thrombosis. J Am Coll Cardiol 2009; 53: 849-56.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 849-856
    • Sibbing, D.1    Braun, S.2    Morath, T.3    Mehilli, J.4    Vogt, W.5    Schomig, A.6    Kastrati, A.7    Von Beckerath, N.8
  • 52
    • 59849120163 scopus 로고    scopus 로고
    • Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up
    • Marcucci R, Gori AM, Paniccia R, Giusti B, Valente S, Giglioli C, Buonamici P, Antoniucci D, Abbate R, Gensini GF. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up. Circulation 2009; 119: 237-42.
    • (2009) Circulation , vol.119 , pp. 237-242
    • Marcucci, R.1    Gori, A.M.2    Paniccia, R.3    Giusti, B.4    Valente, S.5    Giglioli, C.6    Buonamici, P.7    Antoniucci, D.8    Abbate, R.9    Gensini, G.F.10
  • 53
    • 58649095289 scopus 로고    scopus 로고
    • Impact of high loading and maintenance dose of clopidogrel within the first 15-days after percutaneous coronary intervention on patient outcome
    • Lemesle G, Delhaye C, Sudre A, Broucqsault D, Rosey G, Bauters C, Lablanche JM. Impact of high loading and maintenance dose of clopidogrel within the first 15-days after percutaneous coronary intervention on patient outcome. Am Heart J 2009; 157: 375-82.
    • (2009) Am Heart J , vol.157 , pp. 375-382
    • Lemesle, G.1    Delhaye, C.2    Sudre, A.3    Broucqsault, D.4    Rosey, G.5    Bauters, C.6    Lablanche, J.M.7
  • 56
    • 67651094208 scopus 로고    scopus 로고
    • Incidence and predictors of stroke associated with percutaneous coronary intervention
    • Aggarwal A, Dai D, Rumsfeld JS, Klein LW, Roe MT. Incidence and predictors of stroke associated with percutaneous coronary intervention. Am J Cardiol 2009; 104: 349-53.
    • (2009) Am J Cardiol , vol.104 , pp. 349-353
    • Aggarwal, A.1    Dai, D.2    Rumsfeld, J.S.3    Klein, L.W.4    Roe, M.T.5
  • 57
    • 0032752582 scopus 로고    scopus 로고
    • Prediction of cardiac events after uncomplicated acute myocardial infarction by clinical variables and dobutamine stress test
    • Salustri A, Ciavatti M, Seccareccia F, Palamara A. Prediction of cardiac events after uncomplicated acute myocardial infarction by clinical variables and dobutamine stress test. J Am Coll Cardiol 1999; 34: 435-40.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 435-440
    • Salustri, A.1    Ciavatti, M.2    Seccareccia, F.3    Palamara, A.4
  • 58
    • 33750079553 scopus 로고    scopus 로고
    • Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin
    • Gilard M, Arnaud B, Le Gal G, Abgrall JF, Boschat J. Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin. J Thromb Haemost 2006; 4: 2508-9.
    • (2006) J Thromb Haemost , vol.4 , pp. 2508-2509
    • Gilard, M.1    Arnaud, B.2    Le Gal, G.3    Abgrall, J.F.4    Boschat, J.5
  • 59
    • 33947328091 scopus 로고    scopus 로고
    • Thienopyridines in cardiovascular disease: focus on clopidogrel resistance
    • Siller-Matula J, Schror K, Wojta J, Huber K. Thienopyridines in cardiovascular disease: focus on clopidogrel resistance. Thromb Haemost 2007; 97: 385-93.
    • (2007) Thromb Haemost , vol.97 , pp. 385-393
    • Siller-Matula, J.1    Schror, K.2    Wojta, J.3    Huber, K.4
  • 60
    • 54949144309 scopus 로고    scopus 로고
    • Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
    • Zanger UM, Turpeinen M, Klein K, Schwab M. Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation. Anal Bioanal Chem 2008; 392: 1093-108.
    • (2008) Anal Bioanal Chem , vol.392 , pp. 1093-1108
    • Zanger, U.M.1    Turpeinen, M.2    Klein, K.3    Schwab, M.4
  • 61
    • 68049115736 scopus 로고    scopus 로고
    • Drug interaction between clopidogrel and proton pump inhibitors
    • Khalique SC, Cheng-Lai A. Drug interaction between clopidogrel and proton pump inhibitors. Cardiol Rev 2009; 17: 198-200.
    • (2009) Cardiol Rev , vol.17 , pp. 198-200
    • Khalique, S.C.1    Cheng-Lai, A.2
  • 62
    • 3242884174 scopus 로고    scopus 로고
    • Commentary: the HRT story: vindication of old epidemiological theory
    • Vandenbroucke JP. Commentary: the HRT story: vindication of old epidemiological theory. Int J Epidemiol 2004; 33: 456-7.
    • (2004) Int J Epidemiol , vol.33 , pp. 456-457
    • Vandenbroucke, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.