In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding

Journal of Burn Care and Research

Volumn 33, Issue 2, 2012, Pages

  Hamrahi, Victoria F ^a   Goverman, Jeremy ^a,b,c   Jung, Walter ^a,b,c   Wu, Joseph C ^d   Fischman, Alan J ^b,c   Tompkins, Ronald G ^a,b,c   Yu, Yong Y ^a,b,c   Fagan, Shawn P ^a,b,c   Carter, Edward A ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; LUCIFERASE; THYMIDINE KINASE; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BURN; CELL GROWTH; CONTROLLED STUDY; EMBRYONIC STEM CELL; EXPERIMENTAL MOUSE; HOST CELL; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PROGENY;

ANALYSIS OF VARIANCE; ANIMALS; BURNS; CELL CULTURE TECHNIQUES; CELL LINE; CHONDROITIN SULFATES; COLLAGEN; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; LUCIFERASES; MALE; MICE; MOLECULAR IMAGING; THYMIDINE KINASE;

EID: 84859173652     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0b013e3182331d1c     Document Type: Article

References (16)

1. Shumakov VI, Onishchenko NA, Rasulov MF, Krasheninnikov ME, Zaidenov VA. Mesenchymal bone marrow stem cells more effectively stimulate regeneration of deep burn wounds than embryonic fibroblasts. Bull Exp Biol Med 2003;136:192-5. (Pubitemid 38132992)
2. Mansilla E, Marin GH, Drago H, et al. Bloodstream cells phenotypically identical to human mesenchymal bone marrow stem cells circulate in large amounts under the influence of acute large skin damage: new evidence for their use in regenerative medicine. Transplant Proc 2006;38:967-9.
3. Burd A, Ahmed K, Lam S, Ayyappan T, Huang L. Stem cell strategies in burns care. Burns 2007;33:282-91. (Pubitemid 46428493)
4. Rasulov MF, Vasilchenkov AV, Onishchenko NA, et al. First experience of the use bone marrow mesenchymal stem cells for the treatment of a patient with deep skin burns. Bull Exp Biol Med 2005;139:141-4.
5. Boyce ST, Warden GD. Principles and practices for treatment of cutaneous wounds with cultured skin substitutes. Am J Surg 2002;183:445-56. (Pubitemid 34442512)
6. Boyce ST, Kagan RJ, Meyer NA, Yakuboff KP, Warden GD. The 1999 clinical research award. Cultured skin substitutes combined with Integra Artificial Skin to replace native skin autograft and allograft for the closure of excised full-thickness burns. J Burn Care Rehabil 1999;20:453-61. (Pubitemid 30007823)
7. Li Z, Lee A, Huang M, et al. Imaging survival and function of transplanted cardiac resident stem cells. J Am Coll Cardiol 2009;53:1229-40.
8. Wu JC, Spin JM, Cao F, et al. Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. Physiol Genomics 2006;25:29-38.
9. Hamblin MR, O'Donnell DA, Murthy N, Contag CH, Hasan T. Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem Photobiol 2002;75:51-7.
10. Abe S, Boyer C, Liu X, et al. Cells derived from the circulation contribute to the repair of lung injury. Am J Respir Crit Care Med 2004;170:1158-63. (Pubitemid 39577372)
11. Gonzalez-Rey E, Anderson P, Gonzalez MA, Rico L, Buscher D, Delgado M. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut 2009;58:929-39.
12. Desai MH, Mlakar JM, McCauley RL, et al. Lack of long term durability of cultured keratinocyte burn wound coverage: a case report. J Burn Care Rehabil 1991;12:540-5.
13. Cuono C, Langdon R, Birchall N, Barttelbort S, McGuire J. Composite autologous-allogeneic skin replacement: development and clinical application. Plast Reconstr Surg 1987;80:626-37.
14. Wood FM, Stoner ML, Fowler BV, Fear MW. The use of a non-cultured autologous cell suspension and Integra dermal regeneration template to repair full-thickness skin wounds in a porcine model: a one-step process. Burns 2007;33:693-700. (Pubitemid 47248084)
15. Ojeh NO, Frame JD, Navsaria HA. In vitro characterization of an artificial dermal scaffold. Tissue Eng 2001;7:457-72. (Pubitemid 32734777)
16. Jones I, James SE, Rubin P, Martin R. Upward migration of cultured autologous keratinocytes in Integra artificial skin: a preliminary report. Wound Repair Regen 2003;11:132-8. (Pubitemid 36514825)