Role of peroxisome proliferator-activated receptor gamma agonist in improving hepatic steatosis: Possible molecular mechanism

Journal of Diabetes Investigation

Volumn 3, Issue 2, 2012, Pages 93-95

  Park, Cheol Young ^a   Park, Sung Woo ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADENYLATE KINASE; ALPHA TOCOPHEROL; BETAINE; BIGUANIDE; CANNABINOID 1 RECEPTOR ANTAGONIST; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN; SIRTUIN 1; SIRTUIN 6; TRANSCRIPTION FACTOR FKHR; URSODEOXYCHOLIC ACID;

ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE GENE; CLINICAL EFFECTIVENESS; DIABETES MELLITUS; DISEASE ASSOCIATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; EDITORIAL; ENZYME PHOSPHORYLATION; FATTY LIVER; FLUID RETENTION; FORKHEAD BOX O1 GENE; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; INSULIN SENSITIVITY; LIFESTYLE MODIFICATION; MOLECULAR DYNAMICS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OSTEOPOROSIS; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIDE EFFECT; SIGNAL TRANSDUCTION; WEIGHT GAIN;

EID: 84859114508     PISSN: 20401116     EISSN: 20401124     Source Type: Journal    
DOI: 10.1111/j.2040-1124.2012.00204.x     Document Type: Editorial

References (5)

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3. Kim HS, Xiao C, Wang RH, et al. Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis. Cell Meta 2010; 12: 224-236.
4. Yang SJ, Choi JM, Chae SW, et al. Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats. PLoS One 2011; 23: e17057.
5. Kang JG, Park CY, Ihm SH, et al. Mechanisms of adipose tissue redistribution with rosiglitazone treatment in various adipose depots. Metabolism 2010; 59: 46-53.