Folic acid-functionalized human serum albumin nanocapsules for targeted drug delivery to chronically activated macrophages

International Journal of Pharmaceutics

Volumn 427, Issue 2, 2012, Pages 460-466

  Rollett, Alexandra ^a   Reiter, Tamara ^a   Nogueira, Patricia ^b   Cardinale, Massimiliano ^a   Loureiro, Ana ^c   Gomes, Andreia ^c   Cavaco Paulo, Artur ^c   Moreira, Alexandra ^b   Carmo, Alexandre M ^b,d   Guebitz, Georg M ^a,e  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d UNIVERSITY OF PORTO   (Portugal)

^e AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY   (Austria)

Author keywords

Albumin nanocapsules; Drug delivery; Folate receptor; Macrophages; Targeted

Indexed keywords

EMULSIFYING AGENT; FLUORESCENT DYE; FOLIC ACID; HUMAN SERUM ALBUMIN; NANOCAPSULE;

ARTICLE; CONFOCAL LASER MICROSCOPY; CROSS LINKING; DRUG DELIVERY SYSTEM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIGHT SCATTERING; MACROPHAGE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; ZETA POTENTIAL;

CELL SEPARATION; CELL SURVIVAL; CROSS-LINKING REAGENTS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EMULSIONS; FLOW CYTOMETRY; FLUORESCENT DYES; FOLATE RECEPTOR 2; FOLIC ACID; HUMANS; LIGHT; MACROPHAGE ACTIVATION; MACROPHAGES; MICROSCOPY, CONFOCAL; NANOCAPSULES; OXAZINES; PARTICLE SIZE; SCATTERING, RADIATION; SERUM ALBUMIN; SURFACE PROPERTIES; XANTHENES;

EID: 84859105871     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.028     Document Type: Article

References (28)

1. I.E. Adamopoulos, A. Sabokbar, B.P. Wordsworth, A. Carr, D.J. Ferguson, and N.A. Athanasou Synovial fluid macrophages are capable of osteoclast formation and resorption J. Pathol. 208 2006 35 43
2. F. Ahsan, I.P. Rivas, M.A. Khan, and A.I. Torres Suarez Targeting to macrophages: role of physicochemical properties of particulate carriers - liposomes and microspheres - on the phagocytosis by macrophages J. Control. Release 79 2002 29 40
3. A. Albert, D.J. Brown, and G. Cheeseman 812. Pteridine studies. Part III: the solubility and the stability to hydrolysis of pteridines J. Chem. Soc. 1952 4219 4232
4. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
5. M.P. Desai, V. Labhasetwar, G.L. Amidon, and R.J. Levy Gastrointestinal uptake of biodegradable microparticles: effect of particle size Pharm. Res. 13 1996 1838 1845
6. A. Gabizon, A.T. Horowitz, D. Goren, D. Tzemach, F. Mandelbaum-Shavit, M.M. Qazen, and S. Zalipsky Targeting folate receptor with folate linked to extremities of poly(ethylene glycol)-grafted liposomes: in vitro studies Bioconjug. Chem. 10 1999 289 298
7. M.W. Grinstaff, and K.S. Suslick Air-filled proteinaceous microbubbles: synthesis of an echo-contrast agent PNAS 88 1991 7708 7710
8. M.W. Grinstaff, and K.S. Suslick Proteinaceous microspheres Am. Chem. Soc. 1992 218 226
9. Y.K. Kim, J.Y. Choi, M.K. Yoo, H.L. Jiang, R. Arote, Y.H. Je, M.H. Cho, and C.S. Cho Receptor-mediated gene delivery by folate-PEG-baculovirus in vitro J. Biotechnol. 131 2007 353 361
10. A. Lamprecht, U. Schäfer, and C.M. Lehr Structural analysis of microparticles by confocal laser scanning microscopy AAPS PharmSci 1 2000 10 19
11. K. Langer, S. Balthasar, V. Vogel, N. Dinauer, H. von Briesen, and D. Schubert Optimization of the preparation process for human serum albumin (HSA) nanoparticles Int. J. Pharm. 257 2003 169 180
12. V.J. Mohanraj, and Y. Chen Nanoparticles - a review Trop. J. Pharm. Res. 5 2006 561 573
13. B.G. Müller, H. Leuenberger, and T. Kissel Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique Pharm. Res. 13 1996 32 37
14. N. Nakashima-Matsushita, T. Homma, S. Yu, T. Matsuda, N. Sunahara, T. Nakamura, M. Tsukano, M. Ratnam, and T. Matsuyama Selective expression of folate receptor β and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis Arthritis Rheum. 42 1999 1609 1616
15. J. Panyam, and V. Labhasetwar Biodegradable nanoparticles for drug and gene delivery to cells and tissue Adv. Drug Deliv. Rev. 55 2003 329 347
16. C.M. Paulos, M.J. Turk, G.J. Breur, and P.S. Low Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis Adv. Drug Deliv. Rev. 56 2004 1205 1217
17. A. Puig-Kröger, E. Sierra-Filardi, A. Dominguez-Soto, R. Samaniego, M.T. Corcuera, F. Gomez-Aguado, M. Ratnam, P. Sanchez-Mateos, and A.L. Corbi Folate receptor β is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages Cancer Res. 69 2009 9395 9403
18. J.F. Ross, H. Wang, F.G. Behm, P. Mathew, M. Wu, R. Booth, and M. Ratnam Folate receptor type β is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia Cancer 85 1999 348 357
19. G. Schett Review: immune cells and mediators of inflammatory arthritis Autoimmunity 41 2008 224 229
20. S. Sebak, M. Mirzaei, M. Malhotra, A. Kulamarva, and S. Prakash Human serum albumin nanoparticles as an efficient noscapine drug delivery system for potential use in breast cancer: preparation and in vitro analysis Int. J. Nanomed. 5 2010 525 532
21. R. Silva, H. Ferreira, and A. Cavaco-Paulo Sonoproduction of liposomes and protein particles as templates for delivery purposes Biomacromolecules 12 2011 3353 3368
22. B. Stella, S. Arpicco, M.T. Peracchia, D. Desmaele, J. Hoebeke, M. Renoir, J. D'Angelo, L. Cattel, and P. Couvreur Design of folic acid-conjugated nanoparticles for drug targeting J. Pharm. Sci. 89 2000 1452 1464
23. S. Suri, H. Fenniri, and B. Singh Nanotechnology-based drug delivery systems J. Occup. Med. Toxicol. 2 2007 16
24. M.J. Turk, G.J. Breur, W.R. Widmer, C.M. Paulos, L.C. Xu, L.A. Grote, and P.S. Low Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis Arthritis Rheum. 46 2002 1947 1955
25. K. Ulbrich, M. Michaelis, F. Rothweiler, T. Knobloch, P. Sithisarn, J. Cinatl, and Kreuter Jr. Interaction of folate-conjugated human serum albumin (HSA) nanoparticles with tumour cells Int. J. Pharm. 406 2011 128 134
26. J.W. Van Der Heijden, R. Oerlemans, B.A.C. Dijkmans, H. Qi, C.J.V. Laken, W.F. Lems, A.L. Jackman, M.C. Kraan, P.P. Tak, M. Ratnam, and G. Jansen Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients Arthritis Rheum. 60 2009 12 21
27. L.S. Witus, and M.B. Francis Using synthetically modified proteins to make new materials Acc. Chem. Res. 44 2011 774 783
28. W. Xia, A.R. Hilgenbrink, E.L. Matteson, M.B. Lockwood, J.X. Cheng, and P.S. Low A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages Blood 113 2009 438 446