Measuring multiple neurochemicals and related metabolites in blood and brain of the rhesus monkey by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 402, Issue 8, 2012, Pages 2545-2554

  Li, Juan ^a   Von Pföstl, Veronika ^a   Zaldivar, Daniel ^a,d   Zhang, Xiaozhe ^b   Logothetis, Nikos ^a,c   Rauch, Alexander ^a  

^a MAX PLANCK INSTITUTE FOR BIOLOGICAL CYBERNETICS   (Germany)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Blood; Brain; HILIC MS; Microdialysis; Neurochemicals; Rhesus monkey

Indexed keywords

ANALYTICAL METHOD; BLOOD SAMPLES; CHROMATOGRAPHY-MASS SPECTROMETRY; CLINICAL RESEARCH; CONCENTRATION RATIO; DETECTION LIMITS; DIALYSATES; HIGH SENSITIVITY; HILIC-MS; HYDROPHILIC INTERACTION; HYDROPHILIC INTERACTION CHROMATOGRAPHY; IN-VIVO MEASUREMENT; IONIZATION MODES; LIMITS OF DETECTION; MATRIX EFFECTS; MICRO-DIALYSIS; MICRODIALYSIS SAMPLING; NEUROCHEMICALS; NON-HUMAN PRIMATE; POLAR SUBSTANCES; PYRUVATES; QUATERNARY AMMONIUM; RHESUS MONKEY;

AMINO ACIDS; BLOOD; BRAIN; DIALYSIS; ELECTROSPRAY IONIZATION; IONIZATION; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; METABOLISM; METABOLITES;

BLOOD VESSELS;

ACETYLCHOLINE; GLUTAMIC ACID; GLUTAMINE; LACTIC ACID; PYRUVIC ACID;

ANIMAL; ARTICLE; BLOOD; BLOOD ANALYSIS; BRAIN; BRAIN LEVEL; CHEMICAL PHENOMENA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MICRODIALYSIS; RHESUS MONKEY;

ACETYLCHOLINE; ANIMALS; BLOOD CHEMICAL ANALYSIS; BRAIN; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUTAMIC ACID; GLUTAMINE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LACTIC ACID; MACACA MULATTA; MASS SPECTROMETRY; MICRODIALYSIS; PYRUVIC ACID;

MACACA MULATTA; PRIMATES;

EID: 84859099696     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5427-z     Document Type: Article

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