Metyrapone effects on systemic and cerebral energy metabolism

European Journal of Pharmacology

Volumn 682, Issue 1-3, 2012, Pages 92-98

  Drouet, Jean Baptiste ^a   Fauvelle, Florence ^a   Batandier, Cécile ^b   Peinnequin, André ^a   Alonso, Antonia ^a   Fidier, Nadine ^a   Maury, Renaud ^a   Poulet, Laurent ^a,b   Buguet, Alain ^c,d   Cespuglio, Raymond ^c   Canini, Frédéric ^a,e  

^a CENTRE DE RECHERCHES   (France)

^b UNIV GRENOBLE ALPES   (France)

^c UNIVERSITÉ LYON 1   (France)

^d Université Claude Bernard Lyon 1 ^*  (Congo)

^e Ecole du Val de Grace   (France)

Author keywords

Glutamine; Hyperglycemia; Hypothermia; Lactate; Magnetic Resonance Spectroscopy; Mitochondrion

Indexed keywords

4 AMINOBUTYRIC ACID; CORTICOSTERONE; GLUCOCORTICOID; GLUCOSE; GLUTAMIC ACID; HEAT SHOCK PROTEIN 70; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LACTIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; METYRAPONE; N ACETYLASPARTIC ACID; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; BRAIN MITOCHONDRION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; ENERGY METABOLISM; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; HYPOTHERMIA; LACTATE BLOOD LEVEL; MALE; METABOLITE; MITOCHONDRIAL RESPIRATION; NEUROPROTECTION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTON HIGH RESOLUTION MAGIC ANGLE SPINNING MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BRAIN; ENERGY METABOLISM; ENZYME INHIBITORS; HIPPOCAMPUS; HSP70 HEAT-SHOCK PROTEINS; MALE; METYRAPONE; MITOCHONDRIA; OXYGEN; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC;

EID: 84859099629     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.02.025     Document Type: Article

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