Whole-genome analysis of gene expression associates the ubiquitin-proteasome system with the cardiomyopathy phenotype in disease-sensitized congenic mouse strains

Cardiovascular Research

Volumn 94, Issue 1, 2012, Pages 87-95

  Ivandic, Boris T ^a   Mastitsky, Sergey E ^b   Schönsiegel, Frank ^a   Bekeredjian, Raffi ^a   Eils, Roland ^b,c   Frey, Norbert ^d   Katus, Hugo A ^a   Brors, Benedikt ^b  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Cardiomyopathy; Congenic strain; Gene expression; Mouse; Proteasome

Indexed keywords

BINDING PROTEIN; CALSARCIN 1; DELTA SARCOGLYCAN; LIM PROTEIN; MUSCLE PROTEIN; PROTEASOME; UBIQUITIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONGENIC STRAIN; ECHOCARDIOGRAPHY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INACTIVATION; GENOME ANALYSIS; HEART ASSIST DEVICE; HEART MUSCLE; HEART VENTRICLE FUNCTION; HYPERTROPHIC CARDIOMYOPATHY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

AGE FACTORS; ANIMALS; CARDIOMYOPATHIES; CARRIER PROTEINS; COMPUTATIONAL BIOLOGY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; LIM DOMAIN PROTEINS; MALE; MICE; MICE, 129 STRAIN; MICE, CONGENIC; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCLE PROTEINS; MUTATION; MYOCARDIAL CONTRACTION; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; SARCOGLYCANS; UBIQUITINATION; UBIQUITINS; VENTRICULAR FUNCTION, LEFT;

EID: 84859097246     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs080     Document Type: Article

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