Hypoxia-inducible factor 1 controls the expression of the uncoordinated-5-B receptor, but not of Netrin-1, in first trimester human placenta

International Journal of Developmental Biology

Volumn 55, Issue 10-12, 2011, Pages 981-987

  Dakouane Giudicelli, Mbarka ^a   Alfaidy, Nadia ^b   Bayle, Perrine ^a   de Nonneville, Alexandre Tassin ^a   Studer, Vivien ^a   Rozenberg, Patrick ^c   de Mazancourt, Philippe ^a  

^a CENTRE HOSPITALIER INTERCOMMUNAL   (France)

^b CEA GRENOBLE   (France)

^c Service de Gynécologie Obstétrique et Médecine de la Reproduction   (France)

Author keywords

HIF 1; Human placenta; Hypoxia; Netrin 1; UNC5B

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; NETRIN 1; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; UNCOORDINATED 5B RECEPTOR;

ARTICLE; CELL HYPOXIA; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTROPHOBLAST; DEVELOPMENTAL GENE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; NETRIN 1 GENE; NUCLEOTIDE SEQUENCE; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; UNCOORDINATED 5B RECEPTOR GENE;

ANOXIA; CELL LINE, TUMOR; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; KI-67 ANTIGEN; NERVE GROWTH FACTORS; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; RECEPTORS, CELL SURFACE; RNA, SMALL INTERFERING; TROPHOBLASTS; TUMOR SUPPRESSOR PROTEINS;

EID: 84859094550     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: 10.1387/ijdb.103276md     Document Type: Article

References (20)

1. CIRULLI, V., and YEBRA, M. (2007). Netrins: beyond the brain. Nat Rev Mol Cell Biol 8: 296-306.
2. DAKOUANE-GIUDICELLI, M., DUBOUCHER, C., FORTEMPS, J., MISSEY-KOLB, H., BRULE, D., GIUDICELLI, Y., and DE MAZANCOURT, P. (2010). Characterization and expression of netrin-1 and its receptors UNC5B and DCC in human placenta. J Histochem Cytochem 58: 73-82.
3. ENGELKAMP, D. (2002). Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation. Mech Dev 118: 191-197.
4. HUPPERTZ, B., FRANK, H. G., KINGDOM, J. C., REISTER, F., and KAUFMANN, P. (1998). Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem Cell Biol 110: 495-508.
5. IETTA, F., WU, Y., WINTER, J., XU, J., WANG, J., POST, M., and CANIGGIA, I. (2006). Dynamic HIF1A regulation during human placental development. Biol Reprod 75: 112-121.
6. ILLSLEY N. P., CANIGGIA I. and ZAMUDIO S. (2010). Placental metabolic reprogramming: do changes in the mix of energy-generating substrates modulate fetal growth? Int J Dev Biol. 54: 409-419.
7. JAUNIAUX, E., WATSON, A., and BURTON, G. (2001). Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks' gestation. Am J Obstet Gynecol 184: 998-1003.
8. LEONARDO, E. D., HINCK, L., MASU, M., KEINO-MASU, K., ACKERMAN, S. L., and TESSIER-LAVIGNE, M. (1997). Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors. Nature 386: 833-838.
9. LLAMBI, F., CAUSERET, F., BLOCH-GALLEGO, E., and MEHLEN, P. (2001). Netrin-1 acts as a survival factor via its receptors UNC5H and DCC. EMBO J 20: 2715-2722.
10. MATILAINEN T., HAUGAS M., KREIDBERG J. A. and SALMINEN M. (2007). Analysis of Netrin 1 receptors during inner ear development. Int J Dev Biol. 51: 409-413.
11. NAVANKASATTUSAS, S., WHITEHEAD, K. J., SULI, A., SORENSEN, L. K., LIM, A. H., ZHAO, J., PARK, K. W., WYTHE, J. D., THOMAS, K. R., CHIEN, C. B., and LI, D. Y. (2008). The netrin receptor UNC5B promotes angiogenesis in specific vascular beds. Development 135: 659-67.
12. OZAKI, H., YU, A. Y., DELLA, N., OZAKI, K., LUNA, J. D., YAMADA, H., HACKETT, S. F., OKAMOTO, N., ZACK, D. J., SEMENZA, G. L., and CAMPOCHIARO, P. A. (1999). Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression. Invest Ophthalmol Vis Sci 40: 182-189.
13. RABE, N., GEZELIUS, H., VALLSTEDT, A., MEMIC, F., and KULLANDER, K. (2009). Netrin-1-dependent spinal interneuron subtypes are required for the formation of left-right alternating locomotor circuitry. J Neurosci 29: 15642-15649.
14. RAJAKUMAR, A., and CONRAD, K. P. (2000). Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biol Reprod 63: 559-569.
15. RODESCH, F., SIMON, P., DONNER, C., and JAUNIAUX, E. (1992). Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet Gynecol 80: 283-5.
16. SMITH, S. C., BAKER, P. N. and SYMONDS, E. M. (1997). Placental apoptosis in normal human pregnancy. Am J Obstet Gynecol 177: 57-65.
17. TANIKAWA, C., MATSUDA, K., FUKUDA, S., NAKAMURA, Y. and ARAKAWA H. (2003). p53RDL1 regulates p53-dependent apoptosis. Nat Cell Biol. 5: 216-23.
18. THIEBAULT, K., MAZELIN, L., PAYS, L., LLAMBI, F., JOLY, M. O., SCOAZEC, J. Y., SAURIN, J. C., ROMEO, G. and MEHLEN, P. (2003). The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment. Proc Natl Acad Sci USA 100: 4173-8.
19. WANG, R., WEI, Z., JIN, H., WU, H., YU, C., WEN, W., CHAN, L. N., WEN, Z., and ZHANG, M. (2009). Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor. Mol Cell 33: 692-703.
20. YANG, Y., WANG, Y., DU, Y., ZHU, J. W., GAO, H., and ZOU, L. (2009). [Correlation of netrin-1 expression with invasion of extra villous trophoblasts]. Zhonghua Fu Chan Ke Za Zhi 44: 131-4.