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Volumn 8, Issue 3, 2012, Pages 177-184

Protective activity of fumaria vaillantii extract and monomethyl fumarate on acetaminophen induced hepatotoxicity in mice

Author keywords

Acetaminophen; Fumaria vaillantii; Hepatoprotection; Monomethyl fumarate

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; FUMARIA VAILLANTII EXTRACT; FUMARIC ACID DERIVATIVE; GLUTATHIONE; LACTATE DEHYDROGENASE; MALONALDEHYDE; PARACETAMOL; PLANT EXTRACT; SILYBUM MARIANUM EXTRACT; SILYMARIN; UNCLASSIFIED DRUG;

EID: 84859050339     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2012.177.184     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 66149086193 scopus 로고    scopus 로고
    • Evaluation of the hepatoprotective effect of Fumaria parviflora and Momordica balsamina from Saudi folk medicine against experimentally induced liver injury in rats
    • Alqasoumi, S.I., M.S. Al-Dosari, A.M. AlSheikh and M.S. Abdel-Kader, 2009. Evaluation of the hepatoprotective effect of Fumaria parviflora and Momordica balsamina from Saudi folk medicine against experimentally induced liver injury in rats. Res. J. Med. Plant 3: 9-15.
    • (2009) Res. J. Med. Plant , vol.3 , pp. 9-15
    • Alqasoumi, S.I.1    Al-Dosari, M.S.2    Alsheikh, A.M.3    Abdel-Kader, M.S.4
  • 3
    • 84859062455 scopus 로고    scopus 로고
    • Hepatoprotective mechanism of silymarin Semin
    • Anundi, I., 2006. Hepatoprotective mechanism of silymarin Semin. Liver Dis., 6: 78-92.
    • (2006) Liver Dis , vol.6 , pp. 78-92
    • Anundi, I.1
  • 5
    • 0024452911 scopus 로고
    • Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver
    • Campos, R., A. Garrido, R. GuenaandA. Valenzuela, 1989. Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver. PlantaMed., 55: 417-419.
    • (1989) PlantaMed , vol.55 , pp. 417-419
    • Campos, R.1    Garrido, A.2    Valenzuela, R.3    Guenaand, A.4
  • 6
    • 79957844581 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant activity of root bark of Calotropis procera R
    • Chavda, R., K.R. Vadalia and R. Gokani, 2010. Hepatoprotective and antioxidant activity of root bark of Calotropis procera R. Br. (Asclepediaceae). Int. J. Pharmacol, 6: 937-943.
    • (2010) Br. (Asclepediaceae). Int. J. Pharmacol , vol.6 , pp. 937-943
    • Chavda, R.1    Vadalia, K.R.2    Gokani, R.3
  • 7
    • 67249125961 scopus 로고    scopus 로고
    • Evaluation of the antioxidant effects olZiziphus mauritiana Lam. Leaf extracts against chronic ethanol-induced hepatotoxicity in rat liver
    • Dahiru, D. and O. Obidoa, 2007. Evaluation of the antioxidant effects olZiziphus mauritiana Lam. Leaf extracts against chronic ethanol-induced hepatotoxicity in rat liver. Afr. J. Tradit. Complement. Altern. Med., 5: 39-45.
    • (2007) Afr. J. Tradit. Complement. Altern. Med , vol.5 , pp. 39-45
    • Dahiru, D.1    Obidoa, O.2
  • 8
    • 33847011682 scopus 로고    scopus 로고
    • Protective effects of silymarin, a milk thistle (Silybium marianum) derivative on ethanol-induced oxidative stress in liver
    • Das, S.K. and D.M. Vasudevan, 2006. Protective effects of silymarin, a milk thistle (Silybium marianum) derivative on ethanol-induced oxidative stress in liver. Indian J. Biochem. Biophys., 43: 306-311.
    • (2006) Indian J. Biochem. Biophys , vol.43 , pp. 306-311
    • Das, S.K.1    Vasudevan, D.M.2
  • 9
    • 75349113039 scopus 로고    scopus 로고
    • Protective effect of Moringa oleifera Lam. and Lannea kerstingii extracts against cadmium and ethanol-induced lipid peroxidation
    • Diallo, A., K. Eklu-Gadegkeku, T. Mobio, S. Moukha and A. Agbonon, et at, 2009. Protective effect of Moringa oleifera Lam. and Lannea kerstingii extracts against cadmium and ethanol-induced lipid peroxidation. J. Pharma. Toxicol., 4: 160-166.
    • (2009) J. Pharma. Toxicol , vol.4 , pp. 160-166
    • Diallo, A.1    Eklu-Gadegkeku, K.2    Mobio, T.3    Moukha, S.4    Agbonon, A.5
  • 10
    • 84859042598 scopus 로고    scopus 로고
    • Efficacy of different medical herbal preparations as hepatoprotective agents
    • Ellithy, M.M. and S.A. Nada, 2006. Efficacy of different medical herbal preparations as hepatoprotective agents. Toxicol. Lett, 164: S311-S312.
    • (2006) Toxicol. Lett , vol.164
    • Ellithy, M.M.1    Nada, S.A.2
  • 11
    • 0025127633 scopus 로고
    • Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal
    • Esterbauer, H. and K.H. Cheeseman, 1990. Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods Enzymol, 186: 407-421.
    • (1990) Methods Enzymol , vol.186 , pp. 407-421
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 12
    • 0018832431 scopus 로고
    • Silybm inhibition of amatoxin uptake in the perfused rat liver
    • Faulstich, H., W. Jahn and T. Wieland, 1980. Silybm inhibition of amatoxin uptake in the perfused rat liver. Arzneimittelforschung, 30: 452-454.
    • (1980) Arzneimittelforschung , vol.30 , pp. 452-454
    • Faulstich, H.1    Jahn, W.2    Wieland, T.3
  • 13
    • 79960009011 scopus 로고    scopus 로고
    • The protective effects of antioxidants and propranolol on hepatotoxicity of TCDD during isolated rat liver perfusion
    • Ghazi-Khansari, M., M. Karami, M. Rezayat, M. Abdollahi, B. Minaie and O. Sabzevari, 2005. The protective effects of antioxidants and propranolol on hepatotoxicity of TCDD during isolated rat liver perfusion. Int. J. Pharmacol., 1: 336-341.
    • (2005) Int. J. Pharmacol , vol.1 , pp. 336-341
    • Ghazi-Khansari, M.1    Karami, M.2    Rezayat, M.3    Abdollahi, M.4    Minaie, B.5    Sabzevari, O.6
  • 14
    • 0030250470 scopus 로고    scopus 로고
    • Selective protective effect of an extract from Fumaria parviflora on paracetamol-induced hepatotoxicity
    • Guam, A.H., K.H Janbaz and M.S. Akhtar, 1996. Selective protective effect of an extract from Fumaria parviflora on paracetamol-induced hepatotoxicity. Gen. Pharmacol., 27: 979-983.
    • (1996) Gen. Pharmacol , vol.27 , pp. 979-983
    • Guam, A.H.1    Janbaz, K.H.2    Akhtar, M.S.3
  • 15
    • 0034097234 scopus 로고    scopus 로고
    • Metabolism of chemical carcinogen
    • Guengrich, F.P., 2000. Metabolism of chemical carcinogen. Carcinogenesis, 21: 345-351.
    • (2000) Carcinogenesis , vol.21 , pp. 345-351
    • Guengrich, F.P.1
  • 16
    • 0025243755 scopus 로고
    • Hepatoprotective activity of andrographolide against galactosamine and paracetamol intoxication in rats
    • Handa, S.S. and A. Sharma, 1990. Hepatoprotective activity of andrographolide against galactosamine and paracetamol intoxication in rats. Ind. J. Med. Res., 92: 284-292.
    • (1990) Ind. J. Med. Res , vol.92 , pp. 284-292
    • Handa, S.S.1    Sharma, A.2
  • 17
    • 0022869536 scopus 로고
    • Natural products and plants as liver protecting drugs
    • Handa, S.S., A. Sharma and K.K. Chakraborti, 1986. Natural products and plants as liver protecting drugs. Fitoterapia, 57: 307-351.
    • (1986) Fitoterapia , vol.57 , pp. 307-351
    • Handa, S.S.1    Sharma, A.2    Chakraborti, K.K.3
  • 18
    • 7544222053 scopus 로고    scopus 로고
    • Acetaminophen-induced hepatotoxicity: Role of metabolic activation, reactive oxygen/nitrogen species and mitochondrial permeability transition
    • Hinson, J.A., A.B. Reid, S.S. McCullough and L.P. James, 2004. Acetaminophen-induced hepatotoxicity: Role of metabolic activation, reactive oxygen/nitrogen species and mitochondrial permeability transition. Drug Metab. Rev., 36: 805-822.
    • (2004) Drug Metab. Rev , vol.36 , pp. 805-822
    • Hinson, J.A.1    Reid, A.B.2    McCullough, S.S.3    James, L.P.4
  • 19
    • 33644510467 scopus 로고    scopus 로고
    • Effect of chloroquine and ascorbic acid interaction on the oxidative stress status of Plasmodium berghei infested mice
    • Iyawe, H. O. T., A.O. Onigbinde and O.O. Aina, 2006. Effect of chloroquine and ascorbic acid interaction on the oxidative stress status of Plasmodium berghei infested mice. Int. J. Pharmacol., 2: 1-4.
    • (2006) Int. J. Pharmacol , vol.2 , pp. 1-4
    • Iyawe, H.O.T.1    Onigbinde, A.O.2    Aina, O.O.3
  • 21
    • 70350123597 scopus 로고    scopus 로고
    • Role of some Egyptian medicinal plants against liver and kidney toxicity induced by cadmium chloride
    • Koriem, K.M., A.R. Farrag, M.A. Badawy and S.A. El-Toumy, 2009. Role of some Egyptian medicinal plants against liver and kidney toxicity induced by cadmium chloride. Toxicol. Mechanisms Methods, 19: 524-534.
    • (2009) Toxicol. Mechanisms Methods , vol.19 , pp. 524-534
    • Koriem, K.M.1    Farrag, A.R.2    Badawy, M.A.3    El-Toumy, S.A.4
  • 23
    • 67349117409 scopus 로고    scopus 로고
    • Hepatoprotective effect of Trichosanthes cucumerina var. cucumerina L. on carbon tetrachloride induced liver damage in rats
    • Kumar, S.S., B.R. Kumar and G.K. Mohan, 2009. Hepatoprotective effect of Trichosanthes cucumerina var. cucumerina L. on carbon tetrachloride induced liver damage in rats. J. Ethanopharmacol., 123: 347-350.
    • (2009) J. Ethanopharmacol , vol.123 , pp. 347-350
    • Kumar, S.S.1    Kumar, B.R.2    Mohan, G.K.3
  • 24
    • 0033063222 scopus 로고    scopus 로고
    • Effect of ethanol and high-fat feeding on hepatic y-glutamylcysteine synthetase subunit expression in the rat
    • Lu, S.C, Z.Z. Huang, J.M. Yang and H. Tsukamoto, 1999. Effect of ethanol and high-fat feeding on hepatic y-glutamylcysteine synthetase subunit expression in the rat. Hepatology, 30: 209-214.
    • (1999) Hepatology , vol.30 , pp. 209-214
    • Lu, S.C.1    Huang, Z.Z.2    Yang, J.M.3    Tsukamoto, H.4
  • 25
    • 60249087270 scopus 로고    scopus 로고
    • Immunomodulatory and antioxidant activity of a polyherbal formulation
    • Meera, S., V.S.S.S.G. Atyam and N.S. Kumar, 2008. Immunomodulatory and antioxidant activity of a polyherbal formulation. Int. J. Pharmacol., 4: 287-291.
    • (2008) Int. J. Pharmacol , vol.4 , pp. 287-291
    • Meera, S.1    Atyam, V.S.S.S.G.2    Kumar, N.S.3
  • 27
    • 38149074837 scopus 로고    scopus 로고
    • Protective effects of Fumaria vaillantii extract on carbon tetrachloride induced hepatotoxicity in rats
    • Mortazavi, R., M. Nassiri-Asl, Z. Farahani-Nick, S. Savad and S.K. Farzam, 2007. Protective effects of Fumaria vaillantii extract on carbon tetrachloride induced hepatotoxicity in rats. Pharmacologynline, 3: 385-393.
    • (2007) Pharmacologynline , vol.3 , pp. 385-393
    • Mortazavi, R.1    Nassiri-Asl, M.2    Farahani-Nick, Z.3    Savad, S.4    Farzam, S.K.5
  • 28
    • 79960023084 scopus 로고    scopus 로고
    • An experimental model for study of the hepatoprotective activity of Nasturtium qfficinale (Watercress) against acetaminophen toxicity using in situ rat liver system
    • Natanzi, A.E., M.H. Ghahremani, H.R. Monsef-Esfahani, B. Minaei, H. Nazarian and 0. Sabzevari, 2009. An experimental model for study of the hepatoprotective activity of Nasturtium qfficinale (Watercress) against acetaminophen toxicity using in situ rat liver system. Eur. J. Sci. Res., 38: 556-564.
    • (2009) Eur. J. Sci. Res , vol.38 , pp. 556-564
    • Natanzi, A.E.1    Ghahremani, M.H.2    Monsef-Esfahani, H.R.3    Minaei, B.4    Nazarian, H.5
  • 30
    • 70350298696 scopus 로고    scopus 로고
    • Immune boosting herbs: Lipid peroxidation in liver homogenate as index of activity
    • Odukoya, O.A., S.I. Inya-Agha and O.O. lion, 2007. Immune boosting herbs: Lipid peroxidation in liver homogenate as index of activity. J. Pharmacol. Toxicol, 2: 190-195.
    • (2007) J. Pharmacol. Toxicol , vol.2 , pp. 190-195
    • Odukoya, O.A.1    Inya-Agha, S.I.2    Lion, O.O.3
  • 31
    • 84984580675 scopus 로고    scopus 로고
    • Acetammophen-induced liver damage in mice: Effects of some medicinal plants on the oxidative defense system
    • Olaleye, M.T. and B.T. Rocha, 2008. Acetammophen-induced liver damage in mice: Effects of some medicinal plants on the oxidative defense system. Exp. Toxicol. Pathol, 59: 319-327.
    • (2008) Exp. Toxicol. Pathol , vol.59 , pp. 319-327
    • Olaleye, M.T.1    Rocha, B.T.2
  • 32
    • 77649290585 scopus 로고    scopus 로고
    • Hepatoprotective effects of ethanolic extract of Cnidoscolus aconitifolius on paracetamol-induced hepatic damage in rats
    • Oyagbemi, A. A. and A. A. Odetola, 2010. Hepatoprotective effects of ethanolic extract of Cnidoscolus aconitifolius on paracetamol-induced hepatic damage in rats. Pak. J. Biol. Sci., 13: 164-169.
    • (2010) Pak. J. Biol. Sci , vol.13 , pp. 164-169
    • Oyagbemi, A.A.1    Odetola, A.A.2
  • 33
    • 79960402741 scopus 로고    scopus 로고
    • Protective effect of leaf extract of Trichilia connaroides on hypercholesterolemia induced oxidative stress
    • Prasanna, G. S. and A. Purnima, 2011. Protective effect of leaf extract of Trichilia connaroides on hypercholesterolemia induced oxidative stress. Int. J. Pharmacol., 7: 106-112.
    • (2011) Int. J. Pharmacol , vol.7 , pp. 106-112
    • Prasanna, G.S.1    Purnima, A.2
  • 34
    • 0017256225 scopus 로고
    • Liver protection by silymarin: In vitro effect on dissociated rat hepatocytes
    • Ramellini, G. and J. Meldolesi, 1976. Liver protection by silymarin: In vitro effect on dissociated rat hepatocytes. Arzneimittelforschung, 26: 69-73.
    • (1976) Arzneimittelforschung , vol.26 , pp. 69-73
    • Ramellini, G.1    Meldolesi, J.2
  • 35
    • 0030881333 scopus 로고    scopus 로고
    • Hepatoprotective activity of the whole plants of Fumaria indica
    • Rao, K.S. and S.H. Mishra, 1996. Hepatoprotective activity of the whole plants of Fumaria indica. Indian J. Pharm. Sci., 59: 165-170.
    • (1996) Indian J. Pharm. Sci , vol.59 , pp. 165-170
    • Rao, K.S.1    Mishra, S.H.2
  • 36
    • 0031948429 scopus 로고    scopus 로고
    • Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica
    • Rao, K.S. and S.H. Mishra, 1998. Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica. J. Ethnopharmacol., 60: 207-213.
    • (1998) J. Ethnopharmacol , vol.60 , pp. 207-213
    • Rao, K.S.1    Mishra, S.H.2
  • 37
    • 0035211762 scopus 로고    scopus 로고
    • The use of silymarin in the treatment of liver diseases
    • Sailer, R., R. Meier and R. Bngnoh, 2001. The use of silymarin in the treatment of liver diseases. Drugs, 61: 2035-2063.
    • (2001) Drugs , vol.61 , pp. 2035-2063
    • Sailer, R.1    Meier, R.2    Bngnoh, R.3
  • 38
    • 0022583887 scopus 로고
    • Biochemical effects of the flavonolignan silibinin on RNA, protein and DNA synthesis in rat liver
    • Sonnenbichler, J. and I. Zetl, 1986. Biochemical effects of the flavonolignan silibinin on RNA, protein and DNA synthesis in rat liver. Progr. Clin. Biol. Res., 213: 319-331.
    • (1986) Progr. Clin. Biol. Res , vol.213 , pp. 319-331
    • Sonnenbichler, J.1    Zetl, I.2
  • 39
    • 18744379129 scopus 로고    scopus 로고
    • Direct determination of alkaloid contents in Fumaria species by GC-MS
    • Suau, R., B. Cabezudo, R. Rico, F. Najera and J.M. Lopez-Romero, 2002. Direct determination of alkaloid contents in Fumaria species by GC-MS. Phytochem. Anal, 13: 363-367.
    • (2002) Phytochem. Anal , vol.13 , pp. 363-367
    • Suau, R.1    Cabezudo, B.2    Rico, R.3    Najera, F.4    Lopez-Romero, J.M.5
  • 40
    • 0021869764 scopus 로고
    • Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat
    • Valenzuela, A., C. Lagos, K. Schmidt and L.A. Videla, 1985. Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat. Biochem. Pharmacol, 34: 2209-2212.
    • (1985) Biochem. Pharmacol , vol.34 , pp. 2209-2212
    • Valenzuela, A.1    Lagos, C.2    Schmidt, K.3    Videla, L.A.4
  • 41
    • 0030907984 scopus 로고    scopus 로고
    • Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients
    • Velussi, M., A.M. Cernigoi, A. De Monte, F. Dapas, C. CaffauandM. Zilh, 1997. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J. Hepatol., 26: 871-879.
    • (1997) J. Hepatol , vol.26 , pp. 871-879
    • Velussi, M.1    Cernigoi, A.M.2    de Monte, A.3    Dapas, F.4    Zilh, C.5    Caffauand, M.6
  • 42
    • 0034859659 scopus 로고    scopus 로고
    • Silymarin: A review of its clinical properties in the management of hepatic disorders
    • Wellington, K. and B. Jarvis, 2001. Silymarin: A review of its clinical properties in the management of hepatic disorders. BioDrugs, 15: 465-489.
    • (2001) BioDrugs , vol.15 , pp. 465-489
    • Wellington, K.1    Jarvis, B.2
  • 43
    • 31344433396 scopus 로고
    • Tehran University Press, Tehran, pp
    • Zargari, A., 1989. Medical Plants. Tehran University Press, Tehran, pp: 170-171.
    • (1989) Medical Plants , pp. 170-171
    • Zargari, A.1
  • 44
    • 1942469598 scopus 로고    scopus 로고
    • Characterization of the acetaminophen-induced degradation of cytochrome p450-3A4 and the proteolytic pathway
    • Zhang, Q., Z. Melnikov and D.E. Feierman, 2004. Characterization of the acetaminophen-induced degradation of cytochrome p450-3A4 and the proteolytic pathway. Basic Clin. Pharmacol. Toxicol., 94: 191-200.
    • (2004) Basic Clin. Pharmacol. Toxicol , vol.94 , pp. 191-200
    • Zhang, Q.1    Melnikov, Z.2    Feierman, D.E.3


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