메뉴 건너뛰기




Volumn 94, Issue 1, 2012, Pages 66-76

Proarrhythmia in KCNJ2-linked short QT syndrome: Insights from modelling

Author keywords

Arrhythmia; Inward rectifier; Short QT syndrome; Ventricular fibrillation

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1;

EID: 84859041826     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs082     Document Type: Article
Times cited : (50)

References (57)
  • 2
    • 0026521375 scopus 로고
    • Role of an inwardly rectifying potassium current in rabbit ventricular action potential
    • Shimoni Y, Clark RB, Giles WR. Role of an inwardly rectifying potassium current in rabbit ventricular action potential. J Physiol 1992;448:709-727.
    • (1992) J Physiol , vol.448 , pp. 709-727
    • Shimoni, Y.1    Clark, R.B.2    Giles, W.R.3
  • 3
    • 0032735979 scopus 로고    scopus 로고
    • An investigation of the role played by the E-4031-sensitive (rapid delayed rectifier) potassium current in isolated rabbit atrioventricular nodal and ventricular myocytes
    • Mitcheson JS, Hancox JC. An investigation of the role played by the E-4031-sensitive (rapid delayed rectifier) potassium current in isolated rabbit atrioventricular nodal and ventricular myocytes. Pflugers Arch 1999;438:843-850.
    • (1999) Pflugers Arch , vol.438 , pp. 843-850
    • Mitcheson, J.S.1    Hancox, J.C.2
  • 4
    • 34447250066 scopus 로고    scopus 로고
    • Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
    • Gaborit N, Le Bouter S, Szuts V, Varro A, Escande D, Nattel S et al. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J Physiol 2007;582:675-693.
    • (2007) J Physiol , vol.582 , pp. 675-693
    • Gaborit, N.1    Le Bouter, S.2    Szuts, V.3    Varro, A.4    Escande, D.5    Nattel, S.6
  • 5
    • 14644400497 scopus 로고    scopus 로고
    • The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis
    • Dhamoon AS, Jalife J. The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis. Heart Rhythm 2005;2:316-324.
    • (2005) Heart Rhythm , vol.2 , pp. 316-324
    • Dhamoon, A.S.1    Jalife, J.2
  • 6
    • 33845783755 scopus 로고    scopus 로고
    • Up-regulation of the inward rectifier K+ current (IK1) in the mouse heart accelerates and stabilizes rotors
    • Noujaim SF, Pandit SV, Berenfeld O, Vikstrom K, Cerrone M, Mironov S et al. Up-regulation of the inward rectifier K+ current (IK1) in the mouse heart accelerates and stabilizes rotors. J Physiol 2007;578:315-326.
    • (2007) J Physiol , vol.578 , pp. 315-326
    • Noujaim, S.F.1    Pandit, S.V.2    Berenfeld, O.3    Vikstrom, K.4    Cerrone, M.5    Mironov, S.6
  • 7
    • 0035907032 scopus 로고    scopus 로고
    • Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome
    • Plaster NM, Tawil R, Tristani-Firouzi M, Canun S, Bendahhou S, Tsunoda A et al. Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. Cell 2001;105:511-519.
    • (2001) Cell , vol.105 , pp. 511-519
    • Plaster, N.M.1    Tawil, R.2    Tristani-Firouzi, M.3    Canun, S.4    Bendahhou, S.5    Tsunoda, A.6
  • 8
    • 0036324229 scopus 로고    scopus 로고
    • Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
    • Tristani-Firouzi M, Jensen JL, Donaldson MR, Sansone V, Meola G, Hahn A et al. Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome). J Clin Invest 2002;110:381-388.
    • (2002) J Clin Invest , vol.110 , pp. 381-388
    • Tristani-Firouzi, M.1    Jensen, J.L.2    Donaldson, M.R.3    Sansone, V.4    Meola, G.5    Hahn, A.6
  • 11
    • 33644815940 scopus 로고    scopus 로고
    • The short QT syndrome as a paradigm to understand the role of potassium channels in ventricular fibrillation
    • Cerrone M, Noujaim S, Jalife J. The short QT syndrome as a paradigm to understand the role of potassium channels in ventricular fibrillation. J Intern Med 2006;259:24-38.
    • (2006) J Intern Med , vol.259 , pp. 24-38
    • Cerrone, M.1    Noujaim, S.2    Jalife, J.3
  • 13
    • 68349152899 scopus 로고    scopus 로고
    • Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome
    • El Harchi A, McPate MJ, Zhang YH, Zhang H, Hancox JC. Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome. J Mol Cell Cardiol 2009;47:743-747.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 743-747
    • El Harchi, A.1    McPate, M.J.2    Zhang, Y.H.3    Zhang, H.4    Hancox, J.C.5
  • 14
    • 0032526920 scopus 로고    scopus 로고
    • Simulation study of cellular electric properties in heart failure
    • Priebe L, Beuckelmann DJ. Simulation study of cellular electric properties in heart failure. Circ Res 1998;82:1206-1223.
    • (1998) Circ Res , vol.82 , pp. 1206-1223
    • Priebe, L.1    Beuckelmann, D.J.2
  • 15
    • 0038069127 scopus 로고    scopus 로고
    • Voltage-dependent gating and block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1
    • Matsuda H, Oishi K, Omori K. Voltage-dependent gating and block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1. J Physiol 2003;548:361-371.
    • (2003) J Physiol , vol.548 , pp. 361-371
    • Matsuda, H.1    Oishi, K.2    Omori, K.3
  • 18
    • 84855272382 scopus 로고    scopus 로고
    • Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome
    • Adeniran I, McPate MJW, Witchel HJ, Hancox JC, Zhang H. Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome. Plos Comput Biol 2011;7:e1002313.
    • (2011) Plos Comput Biol , vol.7
    • Adeniran, I.1    Mjw, M.2    Witchel, H.J.3    Hancox, J.C.4    Zhang, H.5
  • 19
    • 0037013175 scopus 로고    scopus 로고
    • Ionic current basis of electrocardiographic waveforms: A model study
    • Gima K, Rudy Y. Ionic current basis of electrocardiographic waveforms: a model study. Circ Res 2002;90:889-896.
    • (2002) Circ Res , vol.90 , pp. 889-896
    • Gima, K.1    Rudy, Y.2
  • 20
    • 6044255042 scopus 로고    scopus 로고
    • In silico study of action potential and QT interval shortening due to loss of inactivation of the cardiac rapid delayed rectifier potassium current
    • Zhang H, Hancox JC. In silico study of action potential and QT interval shortening due to loss of inactivation of the cardiac rapid delayed rectifier potassium current. Biochem Biophys Res Commun 2004;322:693-699.
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 693-699
    • Zhang, H.1    Hancox, J.C.2
  • 21
    • 24344461845 scopus 로고    scopus 로고
    • Modelling of short QT syndrome in a heterogeneous model of the human ventricular wall
    • Weiss DL, Seemann G, Sachse FB, Dössel O. Modelling of short QT syndrome in a heterogeneous model of the human ventricular wall. Europace 2005;7(Suppl. 2): 105-117.
    • (2005) Europace , vol.7 , Issue.SUPPL. 2 , pp. 105-117
    • Weiss, D.L.1    Seemann, G.2    Sachse, F.B.3    Dössel, O.4
  • 22
    • 0034999515 scopus 로고    scopus 로고
    • Transmural repolarization in the left ventricle in humans during normoxia and ischaemia
    • Taggart P, Sutton PM, Opthof T, Coronel R, Trimlett R, Pugsley W et al. Transmural repolarization in the left ventricle in humans during normoxia and ischaemia. Cardiovasc Res 2001;50:454-462.
    • (2001) Cardiovasc Res , vol.50 , pp. 454-462
    • Taggart, P.1    Sutton, P.M.2    Opthof, T.3    Coronel, R.4    Trimlett, R.5    Pugsley, W.6
  • 23
    • 0031875847 scopus 로고    scopus 로고
    • Transmural heterogeneity of action potentials and Ito1 in myocytes isolated from the human right ventricle
    • Li GR, Feng J, Yue L, Carrier M. Transmural heterogeneity of action potentials and Ito1 in myocytes isolated from the human right ventricle. Am J Physiol 1998;275: H369-377.
    • (1998) Am J Physiol , vol.275
    • Li, G.R.1    Feng, J.2    Yue, L.3    Carrier, M.4
  • 24
    • 0029023244 scopus 로고
    • Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: Evidence for presence of M cells
    • Drouin E, Charpentier F, Gauthier C, Laurent K, Le Marec H. Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells. J Am Coll Cardiol 1995;26:185-192.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 185-192
    • Drouin, E.1    Charpentier, F.2    Gauthier, C.3    Laurent, K.4    Le Marec, H.5
  • 26
    • 77950891253 scopus 로고    scopus 로고
    • M cells in the human heart
    • Antzelevitch C. M cells in the human heart. Circ Res 2010;106:815-817.
    • (2010) Circ Res , vol.106 , pp. 815-817
    • Antzelevitch, C.1
  • 27
    • 43049112485 scopus 로고    scopus 로고
    • Repolarization and vulnerability to re-entry in the human heart with short QT syndrome arising from KCNQ1 mutation - A simulation study
    • Zhang H, Kharche S, Holden AV, Hancox JC. Repolarization and vulnerability to re-entry in the human heart with short QT syndrome arising from KCNQ1 mutation- a simulation study. Prog Biophys Mol Biol 2008;96:112-131.
    • (2008) Prog Biophys Mol Biol , vol.96 , pp. 112-131
    • Zhang, H.1    Kharche, S.2    Holden, A.V.3    Hancox, J.C.4
  • 28
    • 0032480753 scopus 로고    scopus 로고
    • Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations
    • Yan GX, Shimizu W, Antzelevitch C. Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations. Circulation 1998;98: 1921-1927.
    • (1998) Circulation , vol.98 , pp. 1921-1927
    • Yan, G.X.1    Shimizu, W.2    Antzelevitch, C.3
  • 29
    • 61849171169 scopus 로고    scopus 로고
    • Atrial proarrhythmia due to increased inward rectifier current (I(K1)) arising from KCNJ2 mutation - A simulation study
    • Kharche S, Garratt CJ, Boyett MR, Inada S, Holden AV, Hancox JC et al. Atrial proarrhythmia due to increased inward rectifier current (I(K1)) arising from KCNJ2 mutation- a simulation study. Prog Biophys Mol Biol 2008;98:186-197.
    • (2008) Prog Biophys Mol Biol , vol.98 , pp. 186-197
    • Kharche, S.1    Garratt, C.J.2    Boyett, M.R.3    Inada, S.4    Holden, A.V.5    Hancox, J.C.6
  • 30
    • 0036302669 scopus 로고    scopus 로고
    • Electrical refractory period restitution and spiral wave reentry in simulated cardiac tissue
    • Xie F, Qu Z, Garfinkel A, Weiss JN. Electrical refractory period restitution and spiral wave reentry in simulated cardiac tissue. Am J Physiol Heart Circ Physiol 2002;283: H448-H460.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Xie, F.1    Qu, Z.2    Garfinkel, A.3    Weiss, J.N.4
  • 33
    • 77954036452 scopus 로고    scopus 로고
    • Influence of clinical and procedural predictors on ventricular tachycardia ablation outcomes: An analysis from the substrate mapping and ablation in Sinus Rhythm to Halt Ventricular Tachycardia Trial (SMASH-VT)
    • Tung R, Josephson ME, Reddy V, Reynolds MR. Influence of clinical and procedural predictors on ventricular tachycardia ablation outcomes: an analysis from the substrate mapping and ablation in Sinus Rhythm to Halt Ventricular Tachycardia Trial (SMASH-VT). J Cardiovasc Electrophysiol 2010;21:799-803.
    • (2010) J Cardiovasc Electrophysiol , vol.21 , pp. 799-803
    • Tung, R.1    Josephson, M.E.2    Reddy, V.3    Reynolds, M.R.4
  • 35
    • 15944394046 scopus 로고    scopus 로고
    • Short QT syndrome: Successful prevention of sudden cardiac death in an adolescent by implantable cardioverter-defibrillator treatment for primary prophylaxis
    • Schimpf R, Bauersfeld U, Gaita F,Wolpert C. Short QT syndrome: successful prevention of sudden cardiac death in an adolescent by implantable cardioverter-defibrillator treatment for primary prophylaxis. Heart Rhythm 2005;2:416-417.
    • (2005) Heart Rhythm , vol.2 , pp. 416-417
    • Schimpf, R.1    Bauersfeld, U.2    Gaita, F.3    Wolpert, C.4
  • 36
    • 41749114920 scopus 로고    scopus 로고
    • Clinical and molecular genetics of the short QT syndrome
    • Schimpf R, Borggrefe M, Wolpert C. Clinical and molecular genetics of the short QT syndrome. Curr Opin Cardiol 2008;23:192-198.
    • (2008) Curr Opin Cardiol , vol.23 , pp. 192-198
    • Schimpf, R.1    Borggrefe, M.2    Wolpert, C.3
  • 38
    • 22244453703 scopus 로고    scopus 로고
    • Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation
    • Pandit SV, Berenfeld O, Anumonwo JMB, Zaritski RM, Kneller J, Nattel S et al. Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation. Biophys J 2005;88:3806-3821.
    • (2005) Biophys J , vol.88 , pp. 3806-3821
    • Pandit, S.V.1    Berenfeld, O.2    Jmb, A.3    Zaritski, R.M.4    Kneller, J.5    Nattel, S.6
  • 39
    • 33845404813 scopus 로고    scopus 로고
    • Electrophysiological mechanisms of ventricular arrhythmias in relation to Andersen-Tawil syndrome under conditions of reduced IK1: A simulation study
    • Sung RJ, Wu SN, Wu JS, Chang HD, Luo CH. Electrophysiological mechanisms of ventricular arrhythmias in relation to Andersen-Tawil syndrome under conditions of reduced IK1: a simulation study. Am J Physiol Heart Circ Physiol 2006;291: H2597-H2605.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Sung, R.J.1    Wu, S.N.2    Wu, J.S.3    Chang, H.D.4    Luo, C.H.5
  • 40
    • 20344388309 scopus 로고    scopus 로고
    • Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations: Characteristic T-U-wave patterns predict the KCNJ2 genotype
    • Zhang L, Benson DW, Tristani-Firouzi M, Ptacek LJ, Tawil R, Schwartz PJ et al. Electrocardiographic features in Andersen-Tawil syndrome patients with KCNJ2 mutations: characteristic T-U-wave patterns predict the KCNJ2 genotype. Circulation 2005;111:2720-2726.
    • (2005) Circulation , vol.111 , pp. 2720-2726
    • Zhang, L.1    Benson, D.W.2    Tristani-Firouzi, M.3    Ptacek, L.J.4    Tawil, R.5    Schwartz, P.J.6
  • 41
    • 34250166524 scopus 로고    scopus 로고
    • IK1 and cardiac hypoxia: After the long and short QT syndromes, what else can go wrong with the inward rectifier K+ currents
    • Xu Y, Zhang Q, Chiamvimonvat N. IK1 and cardiac hypoxia: after the long and short QT syndromes, what else can go wrong with the inward rectifier K+ currents? J Mol Cell Cardiol 2007;43:15-17.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 15-17
    • Xu, Y.1    Zhang, Q.2    Chiamvimonvat, N.3
  • 42
    • 33845669134 scopus 로고    scopus 로고
    • Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation
    • Domenighetti AA, Boixel C, Cefai D, Abriel H, Pedrazzini T. Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation. J Mol Cell Cardiol 2007;42:63-70.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 63-70
    • Domenighetti, A.A.1    Boixel, C.2    Cefai, D.3    Abriel, H.4    Pedrazzini, T.5
  • 43
    • 33144478924 scopus 로고    scopus 로고
    • IK1: The long and the short QT of it
    • Gross GJ. IK1: the long and the short QT of it. Heart Rhythm 2006;3:336-338.
    • (2006) Heart Rhythm , vol.3 , pp. 336-338
    • Gross, G.J.1
  • 44
    • 75549089028 scopus 로고    scopus 로고
    • Inward rectifier potassium channels control rotor frequency in ventricular fibrillation
    • Jalife J. Inward rectifier potassium channels control rotor frequency in ventricular fibrillation. Heart Rhythm 2009;6:S44-S48.
    • (2009) Heart Rhythm , vol.6
    • Jalife, J.1
  • 45
    • 0038343402 scopus 로고    scopus 로고
    • Blockade of the inward rectifying potassium current terminates ventricular fibrillation in the guinea pig heart
    • Warren M, Guha PK, Berenfeld O, Zaitsev A, Anumonwo JMB, Dhamoon AS et al. Blockade of the inward rectifying potassium current terminates ventricular fibrillation in the guinea pig heart. J Cardiovasc Electrophysiol 2003;14:621-631.
    • (2003) J Cardiovasc Electrophysiol , vol.14 , pp. 621-631
    • Warren, M.1    Guha, P.K.2    Berenfeld, O.3    Zaitsev, A.4    Jmb, A.5    Dhamoon, A.S.6
  • 46
    • 61949107782 scopus 로고    scopus 로고
    • IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers
    • Sekar RB, Kizana E, Cho HC, Molitoris JM, Hesketh GG, Eaton BP et al. IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers. Circ Res 2009;104:355-364.
    • (2009) Circ Res , vol.104 , pp. 355-364
    • Sekar, R.B.1    Kizana, E.2    Cho, H.C.3    Molitoris, J.M.4    Hesketh, G.G.5    Eaton, B.P.6
  • 47
    • 0036219736 scopus 로고    scopus 로고
    • Mother rotors and fibrillatory conduction: A mechanism of atrial fibrillation
    • Jalife J, Berenfeld O, Mansour M. Mother rotors and fibrillatory conduction: a mechanism of atrial fibrillation. Cardiovasc Res 2002;54:204-216.
    • (2002) Cardiovasc Res , vol.54 , pp. 204-216
    • Jalife, J.1    Berenfeld, O.2    Mansour, M.3
  • 49
    • 33846885702 scopus 로고    scopus 로고
    • Cell model for efficient simulation of wave propagation in human ventricular tissue under normal and pathological conditions
    • ten Tusscher KHWJ, Panfilov AV. Cell model for efficient simulation of wave propagation in human ventricular tissue under normal and pathological conditions. Phys Med Biol 2006;51:6141-6156.
    • (2006) Phys Med Biol , vol.51 , pp. 6141-6156
    • Tusscher Khwj, T.1    Panfilov, A.V.2
  • 50
    • 38649084715 scopus 로고    scopus 로고
    • Electromechanical coupling in patients with the short QT syndrome: Further insights into the mechanoelectrical hypothesis of the U wave
    • Schimpf R, Antzelevitch C, Haghi D, Giustetto C, Pizzuti A, Gaita F et al. Electromechanical coupling in patients with the short QT syndrome: further insights into the mechanoelectrical hypothesis of the U wave. Heart Rhythm 2008;5:241-245.
    • (2008) Heart Rhythm , vol.5 , pp. 241-245
    • Schimpf, R.1    Antzelevitch, C.2    Haghi, D.3    Giustetto, C.4    Pizzuti, A.5    Gaita, F.6
  • 51
    • 2442466779 scopus 로고    scopus 로고
    • Electromechanical model of excitable tissue to study reentrant cardiac arrhythmias
    • Nash MP, Panfilov AV. Electromechanical model of excitable tissue to study reentrant cardiac arrhythmias. Prog Biophys Mol Biol 2004;85:501-522.
    • (2004) Prog Biophys Mol Biol , vol.85 , pp. 501-522
    • Nash, M.P.1    Panfilov, A.V.2
  • 53
    • 3843077417 scopus 로고    scopus 로고
    • Activation dynamics in anisotropic cardiac tissue via decoupling
    • Clements JC, Nenonen J, Li PKJ, Horácek BM. Activation dynamics in anisotropic cardiac tissue via decoupling. Ann Biomed Eng 2004;32:984-990.
    • (2004) Ann Biomed Eng , vol.32 , pp. 984-990
    • Clements, J.C.1    Nenonen, J.2    Pkj, L.3    Horácek, B.M.4
  • 55
    • 33845903366 scopus 로고    scopus 로고
    • A comparison of monodomain and bidomain reaction-diffusion models for action potential propagation in the human heart
    • Potse M, Dubé B, Richer J, Vinet A, Gulrajani RM. A comparison of monodomain and bidomain reaction-diffusion models for action potential propagation in the human heart. IEEE Trans Biomed Eng 2006;53:2425-2435.
    • (2006) IEEE Trans Biomed Eng , vol.53 , pp. 2425-2435
    • Potse, M.1    Dubé, B.2    Richer, J.3    Vinet, A.4    Gulrajani, R.M.5
  • 56
    • 84955500449 scopus 로고    scopus 로고
    • Comparing the bidomain and monodomain models in electrocardiology through convergence analysis
    • Bourgault Y, Pierre C. Comparing the bidomain and monodomain models in electrocardiology through convergence analysis. INSMI 2010;hal:00545888.
    • (2010) INSMI , vol.HAL , pp. 00545888
    • Bourgault, Y.1    Pierre, C.2
  • 57
    • 84857981375 scopus 로고    scopus 로고
    • A novel gain-of-function KCNJ2 mutation associated with short QT syndrome impairs inward rectification of Kir2.1 currents
    • Hattori T, Makiyama T, Akao M, Ehara E, Ohno S, Iguchi M et al. A novel gain-of-function KCNJ2 mutation associated with short QT syndrome impairs inward rectification of Kir2.1 currents. Cardiovasc Res 2012;93:666-673.
    • (2012) Cardiovasc Res , vol.93 , pp. 666-673
    • Hattori, T.1    Makiyama, T.2    Akao, M.3    Ehara, E.4    Ohno, S.5    Iguchi, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.