Eosinophils in the oesophageal mucosa: Clinical, pathological and epidemiological relevance in children: A cohort study

BMJ Open

Volumn 2, Issue 1, 2012, Pages

  Cohen, Marta C ^a   Rao, Prithviraj ^a   Thomson, Mike ^a   Al Adnani, Mudher ^a  

^a SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; PROTON PUMP INHIBITOR; STEROID;

ABSCESS; ADOLESCENT; ARTICLE; BASAL CELL; CELL HYPERPLASIA; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; DIAGNOSTIC ACCURACY; DIET THERAPY; DIFFERENTIAL DIAGNOSIS; DYSPHAGIA; EOSINOPHIL; EOSINOPHILIA; EOSINOPHILIC ESOPHAGITIS; EOSINOPHILIC GASTROENTERITIS; EPIDEMIOLOGICAL DATA; ESOPHAGOSCOPY; ESOPHAGUS BIOPSY; ESOPHAGUS MUCOSA; ESOPHAGUS PH; FEEDING BEHAVIOR; FEMALE; FOLLOW UP; FOOD AVERSION; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL SYMPTOM; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFANT; INTERCELLULAR SPACE; MALE; PRESCHOOL CHILD; SCHOOL CHILD; TREATMENT OUTCOME; VOMITING;

EID: 84859033260     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2011-000493     Document Type: Article

References (43)

1. Dahms BB, Qualman SJ, eds. Perspectives in Pediatric Pathology. Gastrointestinal diseases. Perspect Pediatr Pathol. Basel: Karger, 1997;20:14-34.
2. Winter HS, Madara JL, Stafford RJ, et al. Intraepithelial eosinophils: a new diagnostic criterion for reflux esophagitis. Gastroenterology 1982;83:818-23. (Pubitemid 12060519)
3. Lee RG. Marked eosinophilia in esophageal mucosa biopsies. Am J Surg Pathol 1985;9:475-9. (Pubitemid 16194095)
4. Goldman H, Proujansky R. Allergic proctitis and gastroenteritis in children. Clinical and mucosal biopsy features in 53 cases. Am J Surg Pathol 1986;10:75-86. (Pubitemid 16103159)
5. Kelly KJ, Lazenby AJ, Rowe PC, et al. Eosinophilic esophagitis attributed to gastroesophageal reflux: improved with an aminoacidbased formula. Gastroenterology 1995;109:1503-12.
6. Landres RT, Kuster GG, Strum WB. Eosinophilic esophagitis in a patient with vigorous achalasia. Gastroenerology 1978;74:1298-301. (Pubitemid 8352861)
7. Attwood SE, Smyrk TC, Demeester TR, et al. Esophageal eosinophilia with dysphagia. A distinct clinicopathologic syndrome. Dig Dis Sci 1993;38:109-16. (Pubitemid 23039460)
8. Markowitz JE, Liacouras CA. Eosinophilic esophagitis. Gastroenterol Clin North Am 2003;32:949-66. (Pubitemid 37185843)
9. Dellon ES, Aderoju A, Woosley JT, et al. Variability in diagnostic criteria for eosinophilic esophagitis: a systematic review. Am J Gastroenterol 2007;102:2300-13. (Pubitemid 47493837)
10. Furuta GT, Liacouras CA, Collins MH, et al; First International Gastrointestinal Eosinophil Research Symposium (FIGERS) Subcommittees. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology 2007;133:1342-63.
11. Straumann A, Spichtin HP, Bucher KA, et al. Eosinophilic esophagitis: red on microscopy, white on endoscopy. Digestion 2004;70:109-16. (Pubitemid 39370405)
12. Liacouras CA, Wenner WJ, Brown K, et al. Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids. J Pediatr Gastroenterol Nutr 1998;26:380-5. (Pubitemid 28160684)
13. Blanchard C, Rothenberg ME. Basic pathogenesis of eosinophilic esophagitis. Gastrointest Endosc Clin N Am 2008;18:133-43; x. (Pubitemid 350166942)
14. Noel RJ, Putnam PE, Rothenberg ME. Eosinophilic esophagitis. N Engl J Med 2004;351:940-1.
15. Straumann A, Simon HU. Eosinophilic esophagitis: escalating epidemiology? J Allergy Clin Immunol 2004;115:418-19.
16. Straumann A, Beglinger C. Eosinophilic esophagitis: the endoscopist's enigma. Gastrointest Endosc 2006;63:13-15. (Pubitemid 41827770)
17. Rothenberg ME. Eosinophilc gastrointestinal disorders (EGID). J Allergy Clin Immunol 2004;113:11-28; quiz 29.
18. Blanchard C, Wang N, Stringer KF, et al. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest 2006;116:536-47. (Pubitemid 43228372)
19. DeBrosse CW, Case JW, Putnam PE, et al. Quantity and distribution of eosinophils in the gastrointestinal tract of children. Pediatr Dev Pathol 2006;9:210-18. (Pubitemid 44140386)
20. http://www.ons.gov. uk/ons/index.html (accessed Dec. 2011).
21. Odze RD. Pathology of eosinophilic esophagitis: what the clinician needs to know. Am J Gastroenterol 2009;104:485-90.
22. Cury EK, Schraibman V, Faintuch S. Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children-discussion on daily practice. J Pediatr Surg 2004;39:e4-7.
23. Shah A, Kagalwalla AF, Gonsalver N, et al. Histopathologic variability in children with eosinophilic esophagitis. Am J Gastroenterol 2009;104:716-21.
24. Kirsch R, Bokhary R, Marcon MA, et al. Activated mucosal mast cells differentiate eosinophilic (allergic) esophagitis from gastroesophageal reflux disease. J Pediatr Gastroenterol Nutr 2007;44:20-6. (Pubitemid 46071787)
25. Mueller S, Neureiter D, Aigner T, et al. Comparison of histological parameters for the diagnosis of eosinophilic oesophagitis versus gastro-oesophageal reflux disease on oesophageal biopsy material. Histopathology 2008;53:676-84. (Pubitemid 352768719)
26. Lai AL, Girgis S, Liang Y, et al. Diagnostic criteria for eosinophilic esophagitis: a 5-year retrospective review in a pediatric population. J Pediatr Gastroenterol Nutr 2009;49:63-70.
27. Sant'Anna AM, Rolland S, Fournet JC, et al. Eosinophilic esophagitis in children: symptoms, histology and pH probe results. J Pediatr Gastroenterol Nutr 2004;39:373-7.
28. Orenstein SR, Shalaby T, Di Carlo L, et al. The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children. Am J Gastroenterol 2000;95:1422-30. (Pubitemid 30396298)
29. Steiner SJ, Kernek KM, Fitzgerald JF. Severity of basal cell hyperplasia differs in reflux versus eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2006;42:506-9. (Pubitemid 43804727)
30. Calabrese C, Fabbri A, Bortolotti M, et al. Dilated intercellular spaces as a marker of oesophageal damage: comparative results in gastrooesophageal reflux disease with or without bile reflux. Aliment Pharmacol Ther 2003;18:525-32. (Pubitemid 37152293)
31. Solcia E, Villani L, Luinetti O, et al. Altered intercellular glycoconjugates and dilated intercellular spaces of esophageal epithelium in reflux disease. Virchows Arch 2000;236:207-16. (Pubitemid 30168678)
32. Parfitt JR, Gregor JC, Suskin NG, et al. Eosinophilic esophagitis in adults: distinguishing features from gastroesophageal reflux disease: a study of 41 patients. Mod Pathol 2006;19:90-6. (Pubitemid 43250983)
33. Lim JR, Gupta SK, Croffie JM, et al. White specks in the esophageal mucosa: an endoscopic manifestation of non-reflux eosinophilic esophagitis in children. Gastrointest Endosc 2004;59:835-8. (Pubitemid 38879311)
34. Fox VL, Nurko S, Furuta GT. Eosinophilic esophagitis: it's not just kid's stuff. Gastrointest Endosc 2002;56:260-70.
35. Liacouras CA, Ruchelli E. Eosinophilic esophagitis. Curr Opin Pediatr 2004;16:560-6. (Pubitemid 39274393)
36. Furuta GT. Eosinophils in the esophagus: acid is not the only cause. J Pediatr Gastroenterol Nutr 1998;26:468-71. (Pubitemid 28160700)
37. Mishra A, Rothenberg ME. Intratracheal IL-13 induces eosinophilic esophagitis by and IL-5, eotaxin-1 and STAT6-dependent mechanism. Gastroenterology 2003;125:1419-27. (Pubitemid 37409762)
38. Spergel JM, Beausoleil JL, Mascarenhas M, et al. The use of skin prick tests and patch tests to identify causative foods in eosinophilic esopahgitis. J Allergy Clin Immunol 2002;109:363-8. (Pubitemid 34158307)
39. De Angelis P, Markowitz JE, Torroni F, et al. Paediatric eosinophilic oesophagitis: towards early diagnosis and best treatment. Dig Liver Dis 2006;38:245-51. (Pubitemid 44382354)
40. Luo G, Debrosse C, Rothenberg ME, et al. Coexistence of eosinophilic esophagitis (Ee) and celiac disease (CD). Modern Pathol 2009;22:341.
41. King J, Khan S. Eosinophilic esophagitis: perspectives of adult and pediatric gastroenterologists. Dig Dis Sci 2010;55:973-82.
42. Remedios M, Campbell C, Jones DM, et al. Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate. Gatrointest Endosc 2006;63:3-12. (Pubitemid 41827769)
43. Ngo P, Furuta GT, Antonioli DA, et al. Eosinophils in the esophaguspeptic or allergic eosinophilic esophagitis? Case series of three patients with esophageal eosinophilia. Am J Gastroenterol 2006;101:1666-70.