Oriented conjugates of monoclonal and single-domain antibodies with quantum dots for flow cytometry and immunohistochemistry diagnostic applications

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 8232, Issue , 2012, Pages

  Sukhanova, Alyona ^a,b   Even Desrumeaux, Klervi ^c   Millot, Jean Marc ^b   Chames, Patrick ^c   Baty, Daniel ^c   Artemyev, Mikhail ^a,d   Oleinikov, Vladimir ^a,e   Cohen, Jacques H M ^b   Nabiev, Igor ^a,b  

^a NATIONAL RESEARCH NUCLEAR UNIVERSITY MEPHI   (Russian Federation)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^c INSERM   (France)

^d BELARUSIAN STATE UNIVERSITY   (Belarus)

^e SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Colloidal nanocrystals; Diagnostics; Imaging; Oriented conjugation; Quantum dots; Single domain antibodies

Indexed keywords

AFFINITY PURIFICATION; ANTIGEN-BINDING SITES; BIOPSY SAMPLES; C-TERMINAL REGIONS; CARCINOEMBRYONIC ANTIGEN; CHAIN FRAGMENTS; COLLOIDAL NANOCRYSTALS; CYSTEINE RESIDUES; DIAGNOSTIC APPLICATIONS; GOLD STANDARDS; HIGH SPECIFICITY; IMMUNOHISTOCHEMISTRY; MAGNETIC NANOPARTICLES; ORIENTED CONJUGATION; QUANTUM DOT; SINGLE DOMAINS; STANDARD PROTOCOLS; ULTRA-SMALL;

AMINO ACIDS; ANTIGENS; FLOW CYTOMETRY; GENETIC ENGINEERING; IMAGING TECHNIQUES; MEDICAL APPLICATIONS; NANOCRYSTALS; NANOPROBES; PLASMA DIAGNOSTICS; PRECIOUS METALS; SEMICONDUCTOR QUANTUM DOTS;

ANTIBODIES;

EID: 84859025194     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.905896     Document Type: Conference Paper

References (30)

1. Michalet, X., Pinaud, F.F., Bentolila, L.A., Tsay, J.M., Doose, S., Li, J.J., Sundaresan, G., Wu, A.M., Gambhir, S.S. and Weiss, S., Quantum dots for live cells, in vivo imaging, and diagnostics," Science 307, 538-544 (2005). (Pubitemid 40165671)
2. Resch-Genger, U., Grabolle, M., Cavaliere-Jaricot, S., Nitschke, R. and Nann, T., Quantum dots versus organic dyes as fluorescent labels", Nat. Methods 5, 763-775 (2008).
3. Baranov, A., Rakovich, Yu., Donegan, J., Perova, T., Moore, R., Talapin, D., Rogach, A., Masumoto, Y. and Nabiev, I., Effect of ZnS shell thickness on the phonon spectra in CdSe quantum dots," Phys. Rev. B, 68, 1653061-1653067 (2003).
4. Mahmoud, W., Sukhanova, A., Oleinikov, V., Rakovich, Yu., Donegan J.F., Pluot, M., Cohen, J.H.M., Volkov, Yu. and Nabiev, I., Emerging applications of fluorescent nanocrystals quantum dots for micrometastases detection," Proteomics, 10, 700-716 (2010)
5. Sukhanova, A., Susha, A.S., Bek, A., Mayilo, S., Rogach, A.L., Feldmann, J., Oleinikov, V., Reveil, B., Donvito, B., Cohen, J.H.M., Nabiev, I., "Nanocrystal-encoded fluorescent microbeads for proteomics: Antibody profiling and diagnostics of autoimmune diseases," Nano Lett. 7, 2322-2327 (2007).
6. Sukhanova, A., Baranov, A.V., Perova T., Cohen, J.H.M. and Nabiev, I., Controlled self-assembly of nanocrystals in polycrystalline fluorescent dendrites with energy-transfer properties," Angew. Chem. Intl Ed., 45, 2048-2052 (2006). (Pubitemid 44109224)
7. Nabiev, I., Rakovich, A., Sukhanova, A., Lukashev, E., Zagidullin, V., Pachenko, V., Rakovich, Y., Donegan, J.F., Rubin, A.B. and Govorov, A.O., Fluorescent quantum dots as artificial antennas for enhanced light harvesting and energy transfer to photosynthetic reaction centers," Angewandte Chemie Intl Ed. 49, 7217-7221 (2010).
8. Rakovich, A., Sukhanova, A., Lukashev, E., Oleinikov, V.A., Artemyev, M., Gaponik, N., Bouchonville, N., Molinari, M., Troyon, M., Rakovich, Y.P., Donegan, J.F. and Nabiev, I., Resonance energy transfer improves the biological function of bacteriorhodopsin within a hybrid material built from purple membranes and semiconductor quantum dots," Nano Lett. 10 (7), 2640-2648 (2010).
9. Sukhanova, A. and Nabiev, I., Fluorescent nanocrystal-encoded microbeads for multiplexed cancer imaging and diagnosis" Crit. Rev. Oncol. Haematol. 68, 39-59 (2008).
10. Joumaa, N., Lansalot, M., Théretz, A., Elaissari, A., Sukhanova, A., Artemyev, M., Nabiev, I., Cohen, J.H.M., Synthesis of quantum dots-tagged submicronic polystyrene particles by miniemulsion polymerization," Langmuir, 22, 1810-1816 (2006).
11. Xing Y and Rao J., Quantum dot bioconjugates for in vitro diagnostics &in vivo imaging. Cancer Biomark. 4, 307-19 (2008).
12. Sukhanova, A., Devy, J., Venteo, L., Kaplan, H., Artemyev, A., Oleinikov, V., Klinov, D., Pluot, M., Cohen, J.H.M., Nabiev, I., Biocompatible fluorescent nanocrystals for immunolabeling of membrane proteins and cells," Anal. Biochem., 324, 60-67 (2004). (Pubitemid 37491124)
13. Pathak, S., Davidson, M.C. and Silva, G.A., Characterization of the functional binding properties of antibody conjugated quantum dots," Nano Lett. 7, 1839-1845 (2007). (Pubitemid 47197555)
14. Invitrogen : http://probes.invitrogen.com/media/pis/mp19010.pdf
15. Mahmoud, W., Rousserie, G., Reveil, B., Tabary, T., Millot, J.M., Artemyev M, et al., Advanced procedures for labelling of antibodies with quantum dots," Anal. Biochem. 416,180-185 (2011).
16. Amit, A., Mariuzza, R.A., Phillips, S.E. and Poljak, R.J., Three-dimensional structure of an antigen-antibody complex at 2.8 A resolution," Science 233, 747-753 (1986). (Pubitemid 16016225)
17. Yang, L., Mao, H., Wang, Y.A., Cao, Z., Peng, X., Wang, X., et al.," Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging," Small 5, 235-243 (2009).
18. Attarwala, H., Role of antibodies in cancer targeting," J. Nat. Sci. Biol. Med. 1, 53-56 (2010).
19. Holliger, P. and Hudson, P.J., Engineered antibody fragments and the rise of single domains," Nat. Biotechnol. 23, 1126-1136 (2005). (Pubitemid 41486394)
20. Saerens, D., Kinne, J., Bosmans, E., Wernery, U., Muyldermans, S. and Conrath, K., Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen," J. Biol. Chem. 279, 51965-51972 (2004). (Pubitemid 39656566)
21. Perruchini, C., Pecorari, F., Bourgeois, J.P., Duyckaerts, C., Rougeon, F. and Lafaye, P., Llama VHH antibody fragments against GFAP: better diffusion in fixed tissues than classical monoclonal antibodies," Acta Neuropathol. 118, 685-695 (2009).
22. Olichon, A., Schweizer, D., Muyldermans, S. and de Marco, A., Heating as a rapid purification method for recovering correctly-folded thermotolerant VH and VHH domains," BMC Biotechnol. 7, 7-14 (2007).
23. Sukhanova, A., Even-Desrumeaux, K., Kisserli, A., Tabary, T., Reveil, B., Millot, J.M., Chames, P., Baty, D., Artemyev, M., Poly, S., Oleinikov, V.A., Pluot, M., Cohen, J.H.M. and Nabiev, I., Oriented conjugates singledomain antibodies and quantum dots: Toward new generation of ultra-small diagnostic nanoprobes," NanoMedicine: NBM, doi: 10.1016/j.nano.2011.07.007 (2011).
24. Hammarstrom, S., The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues," Semin. Cancer Biol. 9, 67-81 (1999). (Pubitemid 29265523)
25. Wargnier, R., Baranov, A.V., Maslov, V.G., Stsiapura, V., Artemyev, M., Pluot, M., et al., Energy transfer in aqueous solutions of oppositely charged nanoassemblies of CdSe/ZnS core/shell quantum dots and in quantum dot-nanogold assemblies," Nano Lett. 4, 451-457 (2004). (Pubitemid 38402632)
26. Sukhanova, A., Venteo, L., Devy, J., Artemyev, M., Oleinikov, V., Pluot, M. and Nabiev I., Highly stable fluorescent nanocrystals as a novel class of labels for immunohistochemical analysis of paraffin-embedded tissue sections," Lab. Invest. 82, 1259-1262 (2002).
27. Williams, Y., Sukhanova, A., Nowostawska, M., Davies, A.M., Mitchell, S., Oleinikov, V., et al., Probing cell type-specific intracellular nanoscale barriers using size-tuned quantum dots," Small 5, 2581-2588 (2009).
28. Zajac, A., Song, D., Qian, W., Zhukov, T., Protein microarrays and quantum dot probes for early cancer detection," Colloids Surf. B. Biointerfaces 58, 309-314 (2007). (Pubitemid 46921448)
29. Puertas, S., Moros, M., Fernández-Pacheco, R., Ibarra, M.R., Grazu, V. and de la Fuente, J.M., Designing novel nano-immunoassays: antibody orientation vs sensitivity," J. Phys. D: Appl. Phys. 43, 474012 (2010).
30. Puertas, S., Batalla, P., Moros, M., Polo, E., Pino, P., Guisan, J.M., Grazu, V. and de la Fuente, J.M., Taking advantage of unspecific interactions to produce highly active magnetic nanoparticle-antibody conjugates," ACS Nano 5, 4521-4528 (2011).