Llama VHH antibody fragments against GFAP: Better diffusion in fixed tissues than classical monoclonal antibodies

Acta Neuropathologica

Volumn 118, Issue 5, 2009, Pages 685-695

  Perruchini, Claire ^a   Pecorari, Frederic ^b   Bourgeois, Jean Pierre ^c   Duyckaerts, Charles ^a   Rougeon, François ^c   Lafaye, Pierre ^c  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c CNRS   (France)

Author keywords

Camel; GFAP; Homodimeric antibodies; Immunohistochemistry; VHH

Indexed keywords

DNA; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY; MESSENGER RNA; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; IMMUNOGLOBULIN HEAVY CHAIN; RECOMBINANT PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; ARTIODACTYLA; ASTROCYTE; BINDING AFFINITY; BRAIN TISSUE; CELL ISOLATION; CONTROLLED STUDY; DIFFUSION; DNA EXTRACTION; GENE AMPLIFICATION; GENETIC TRANSDUCTION; HUMAN; HUMAN TISSUE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE; MALE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RIBOSOME; TISSUE SECTION; ALZHEIMER DISEASE; ANIMAL; BRAIN CORTEX; BRAIN TUMOR; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE LIBRARY; GENETICS; IMMUNOLOGY; METABOLISM; METHODOLOGY; MOLECULAR WEIGHT; PATHOLOGY;

ALZHEIMER DISEASE; ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN NEOPLASMS; CAMELIDS, NEW WORLD; CEREBRAL CORTEX; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE LIBRARY; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; MALE; MOLECULAR WEIGHT; RECOMBINANT PROTEINS; RNA, MESSENGER; SINGLE-CHAIN ANTIBODIES;

EID: 70449529499     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-009-0572-6     Document Type: Article

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