Monocytes derived from humanized neonatal NOD/SCID/IL2Rγ null mice are phenotypically immature and exhibit functional impairments

Human Immunology

Volumn 73, Issue 4, 2012, Pages 346-354

  Gille, Christian ^a   Orlikowsky, Thorsten W ^b   Spring, Baerbel ^a   Hartwig, Udo F ^c   Wilhelm, Ayline ^a   Wirth, Andreas ^a   Goecke, Barbara ^a   Handgretinger, Rupert ^a   Poets, Christian F ^a   André, Maya C ^a,d  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

Author keywords

Monocyte; Mouse; Neonatal; NOD SCID IL2R null; Phagocytosis

Indexed keywords

ANTIINFLAMMATORY AGENT; B7 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CELL STIMULATION; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOKINE RELEASE; FUNCTIONAL DISEASE; HUMAN; INFLAMMATORY DISEASE; MONOCYTE; MOUSE; NEWBORN; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; SCID MOUSE; SCIENTIST; SEPSIS; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD14; CELL DIFFERENTIATION; CELL LINEAGE; CYTOKINES; FEMALE; HUMANS; IMMUNOPHENOTYPING; INFLAMMATION MEDIATORS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; MONOCYTES; PHAGOCYTOSIS; PHENOTYPE; T-LYMPHOCYTES;

EID: 84859012484     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2012.01.006     Document Type: Article

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