Calcium influx measured at single presynaptic boutons of cerebellar granule cell ascending axons and parallel fibers

Cerebellum

Volumn 11, Issue 1, 2012, Pages 121-131

  Zhang, Wei ^a   Linden, David J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ascending axon; Calcium imaging; Cerebellar granule cell; Parallel fiber; Presynaptic bouton

Indexed keywords

CALCIUM ION;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; ASCENDING AXON; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; NERVE FIBER; NONHUMAN; PARALLEL FIBER; PRESYNAPTIC BOUTON; PRIORITY JOURNAL; RAT; SYNAPSE;

ACTION POTENTIALS; ANIMALS; AXONS; CALCIUM SIGNALING; CEREBELLAR CORTEX; CYTOPLASMIC GRANULES; NERVE FIBERS; NEURAL PATHWAYS; NEUROBIOLOGY; NEURONAL PLASTICITY; NEURONS; NEUROPHYSIOLOGY; ORGAN CULTURE TECHNIQUES; PRESYNAPTIC TERMINALS; PURKINJE CELLS; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTIC TRANSMISSION;

EID: 84859008379     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1007/s12311-009-0151-3     Document Type: Article

References (35)

1. Napper RM, Harvey RJ (1988) Number of parallel fiber synapses on an individual Purkinje cell in the cerebellum of the rat. J Comp Neurol 274(2):168-177
2. Palay SL, Chan-Palay V (1974) Cerebellar cortex: cytology and organization. Springer-Verlag, Berlin
3. Braitenberg V, Atwood RP (1958) Morphological observations on the cerebellar cortex. J Comp Neurol 109(1):1-33
4. Eccles JC, Ito M, Szentagothai J (1967) The cerebellum as a neuronal machine. Springer, Berlin
5. Eccles JC, Llinas R, Sasaki K (1966) Parallel fibre stimulation and the responses induced thereby in the Purkinje cells of the cerebellum. Exp Brain Res 1(1):17-39
6. Coutinho V, Mutoh H, Knopfel T (2004) Functional topology of the mossy fibre-granule cell - Purkinje cell system revealed by imaging of intrinsic fluorescence in mouse cerebellum. Eur J NeuroSci 20(3):740-748 (Pubitemid 39036934)
7. Eccles JC, Sabah NH, Schmidt RF, Taborikova H (1972) Integration by Purkyne cells of mossy and climbing fiber inputs from cutaneous mechanoreceptors. Exp Brain Res 15(5):498-520
8. Kolb FP, Arnold G, Lerch R, Straka H, Buttner-Ennever J (1997) Spatial distribution of field potential profiles in the cat cerebellar cortex evoked by peripheral and central inputs. Neuroscience 81(4):1155-1181
9. Bower JM, Woolston DC (1983) Congruence of spatial organization of tactile projections to granule cell and Purkinje cell layers of cerebellar hemispheres of the albino rat: vertical organization of cerebellar cortex. J Neurophysiol 49(3):745-766
10. Cohen D, Yarom Y (1998) Patches of synchronized activity in the cerebellar cortex evoked by mossy-fiber stimulation: questioning the role of parallel fibers. Proc Natl Acad Sci U S A 95(25):15032-15036 (Pubitemid 29003751)
11. Gao W, Chen G, Reinert KC, Ebner TJ (2006) Cerebellar cortical molecular layer inhibition is organized in parasagittal zones. J Neurosci 26(32):8377-8387 (Pubitemid 44309852)
12. Bower JM (2002) The organization of cerebellar cortical circuitry revisited: implications for function. Ann N Y Acad Sci 978:135-155
13. Sims RE, Hartell NA (2005) Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells. J Neurosci 25(12):3246-3257 (Pubitemid 40463560)
14. Sims RE, Hartell NA (2006) Differential susceptibility to synaptic plasticity reveals a functional specialization of ascending axon and parallel fiber synapses to cerebellar Purkinje cells. J Neurosci 26(19):5153-5159 (Pubitemid 44315296)
15. Isope P, Barbour B (2002) Properties of unitary granule cell→Purkinje cell synapses in adult rat cerebellar slices. J Neurosci 22(22):9668-9678 (Pubitemid 35332850)
16. Walter JT, Dizon MJ, Khodakhah K (2009) The functional equivalence of ascending and parallel fiber inputs in cerebellar computation. J Neurosci 29(26):8462-8473
17. Pichitpornchai C, Rawson JA, Rees S (1994) Morphology of parallel fibres in the cerebellar cortex of the rat: an experimental light and electron microscopic study with biocytin. J Comp Neurol 342(2):206-220 (Pubitemid 24100127)
18. Gundappa-Sulur G, De Schutter E, Bower JM (1999) Ascending granule cell axon: an important component of cerebellar cortical circuitry. J Comp Neurol 408(4):580-596 (Pubitemid 29211184)
19. Lu H, Esquivel AV, Bower JM (2009) 3D electron microscopic reconstruction of segments of rat cerebellar Purkinje cell dendrites receiving ascending and parallel fiber granule cell synaptic inputs. J Comp Neurol 514(6):583-594
20. Sultan F (2000) Exploring a critical parameter of timing in the mouse cerebellar microcircuitry: the parallel fiber diameter. Neurosci Lett 280(1):41-44
21. Chadderton P, Margrie TW, Hausser M (2004) Integration of quanta in cerebellar granule cells during sensory processing. Nature 428(6985):856-860 (Pubitemid 38529500)
22. D'Angelo E, De Zeeuw CI (2009) Timing and plasticity in the cerebellum: focus on the granular layer. Trends Neurosci 32(1):30-40
23. Jorntell H, Ekerot CF (2006) Properties of somatosensory synaptic integration in cerebellar granule cells in vivo. J Neurosci 26(45):11786-11797 (Pubitemid 44772149)
24. Rancz EA, Ishikawa T, Duguid I, Chadderton P, Mahon S, Hausser M (2007) High-fidelity transmission of sensory information by single cerebellar mossy fibre boutons. Nature 450(7173):1245-1248
25. Helmchen F, Borst JG, Sakmann B (1997) Calcium dynamics associated with a single action potential in a CNS presynaptic terminal. Biophys J 72(3):1458-1471 (Pubitemid 27113668)
26. Regehr WG, Atluri PP (1995) Calcium transients in cerebellar granule cell presynaptic terminals. Biophys J 68(5):2156-2170
27. Pelkey KA, Topolnik L, Lacaille JC, McBain CJ (2006) Compartmentalized Ca(2+) channel regulation at divergent mossy-fiber release sites underlies target cell-dependent plasticity. Neuron 52(3):497-510 (Pubitemid 44667429)
28. Brenowitz SD, Regehr WG (2007) Reliability and heterogeneity of calcium signaling at single presynaptic boutons of cerebellar granule cells. J Neurosci 27(30):7888-7898 (Pubitemid 47173305)
29. Zhang W, Linden DJ (2009) Neuromodulation at single presynaptic boutons of cerebellar parallel fibers is determined by bouton size and basal action potential-evoked Ca transient amplitude. J Neurosci 29:15586-15594
30. Beierlein M, Gee KR, Martin VV, Regehr WG (2004) Presynaptic calcium measurements at physiological temperatures using a new class of dextran-conjugated indicators. J Neurophysiol 92(1):591-599 (Pubitemid 38802280)
31. Kreitzer AC, Gee KR, Archer EA, Regehr WG (2000) Monitoring presynaptic calcium dynamics in projection fibers by in vivo loading of a novel calcium indicator. Neuron 27(1):25-32
32. Tank DW, Regehr WG, Delaney KR (1995) A quantitative analysis of presynaptic calcium dynamics that contribute to short-term enhancement. J Neurosci 15(12):7940-7952 (Pubitemid 26006901)
33. Scheuss V, Yasuda R, Sobczyk A, Svoboda K (2006) Nonlinear [Ca2+] signaling in dendrites and spines caused by activity-dependent depression of Ca2+ extrusion. J Neurosci 26(31):8183-8194 (Pubitemid 44315143)
34. Koester HJ, Sakmann B (2000) Calcium dynamics associated with action potentials in single nerve terminals of pyramidal cells in layer 2/3 of the young rat neocortex. J Physiol 529(Pt 3):625-646 (Pubitemid 32051066)
35. Santamaria F, Tripp PG, Bower JM (2007) Feedforward inhibition controls the spread of granule cell-induced Purkinje cell activity in the cerebellar cortex. J Neurophysiol 97(1):248-263 (Pubitemid 46143354)