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Volumn 14, Issue 4, 2012, Pages

Enzyme-encapsulated silica nanoparticle for cancer chemotherapy

Author keywords

Enzyme encapsulation; HRP; IAA; Nanomedicine; Prodrug cancer therapy; Silicate nanoparticle

Indexed keywords

CHEMOTHERAPY; DISEASES; ENZYMES; FOOD PRODUCTS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; ONCOLOGY; SCANNING ELECTRON MICROSCOPY; SILICA; SILICATES;

EID: 84858958654     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-012-0829-1     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 33750014292 scopus 로고    scopus 로고
    • Dextran and 5-aminosalicylic acid (5-ASA) conjugates: Synthesis, characterisation and enzymic hydrolysis
    • DOI 10.1016/j.carres.2006.08.015, PII S0008621506003958
    • Ahmad S, Tester RF, Corbett A, Karkalas J (2006) Dextran and 5-aminosalicylic acid (5-ASA) conjugates: synthesis, characterisation and enzymic hydrolysis. Carbohydr Res 341:2694-2701 (Pubitemid 44572199)
    • (2006) Carbohydrate Research , vol.341 , Issue.16 , pp. 2694-2701
    • Ahmad, S.1    Tester, R.F.2    Corbett, A.3    Karkalas, J.4
  • 3
    • 31044455163 scopus 로고    scopus 로고
    • Enzyme inhibition-based biosensors for food safety and environmental monitoring
    • DOI 10.1016/j.bios.2005.07.012, PII S0956566305002198
    • Amine A, Mohammadi H, Bourais I, Palleschi G (2006) Enzyme inhibition-based biosensors for food safety and environmental monitoring. Biosens Bioelectron 21:1405-1423 (Pubitemid 43122005)
    • (2006) Biosensors and Bioelectronics , vol.21 , Issue.8 , pp. 1405-1423
    • Amine, A.1    Mohammadi, H.2    Bourais, I.3    Palleschi, G.4
  • 4
    • 79959937238 scopus 로고    scopus 로고
    • Nanomaterials for cancer therapy and imaging
    • Bae KH, Chung HJ, Park TG (2011) Nanomaterials for cancer therapy and imaging. Mol Cell 31:295-302
    • (2011) Mol Cell , vol.31 , pp. 295-302
    • Bae, K.H.1    Chung, H.J.2    Park, T.G.3
  • 5
    • 0025134336 scopus 로고
    • Antibody-directed enzyme/prodrug therapy (ADEPT)
    • Bagshawe K (1990) Antibody-directed enzyme/prodrug therapy (ADEPT). Biochem Soc Trans 18:750-752 (Pubitemid 20359291)
    • (1990) Biochemical Society Transactions , vol.18 , Issue.5 , pp. 750-752
    • Bagshawe, K.D.1
  • 7
    • 27644565163 scopus 로고    scopus 로고
    • Hofmeister specific-ion effects on enzyme activity and buffer pH: Horseradish peroxidase in citrate buffer
    • DOI 10.1016/j.molliq.2005.03.003, PII S0167732205000978
    • Bauduin P, Nohmie F, Touraud D, Neueder R, Kunz W, Ninham BW (2006) Hofmeister specific-ion effects on enzyme activity and buffer pH: horseradish peroxidase in citrate buffer. J Mol Liq 123:14-19 (Pubitemid 41562816)
    • (2006) Journal of Molecular Liquids , vol.123 , Issue.1 , pp. 14-19
    • Bauduin, P.1    Nohmie, F.2    Touraud, D.3    Neueder, R.4    Kunz, W.5    Ninham, B.W.6
  • 8
    • 0030028437 scopus 로고    scopus 로고
    • Rates of reaction of indoleacetic acids with horseradish peroxidase compound I and their dependence on the redox potentials
    • DOI 10.1021/bi9514424
    • Candeias LP, Folkes LK, Porssa M, Parrick J, Wardman P (1996) Rates of reaction of indoleacetic acids with horseradish peroxidase compound I and their dependence on the redox potentials. Biochemistry 35:102-108 (Pubitemid 26036412)
    • (1996) Biochemistry , vol.35 , Issue.1 , pp. 102-108
    • Candeias, L.P.1    Folkes, L.K.2    Porssa, M.3    Parrick, J.4    Wardman, P.5
  • 9
    • 0029588221 scopus 로고
    • The choice of prodrugs for gene directed enzyme prodrug therapy of cancer
    • Connors TA (1995) The choice of prodrugs for gene directed enzyme prodrug therapy of cancer. Gene Ther 2:702-709 (Pubitemid 26046568)
    • (1995) Gene Therapy , vol.2 , Issue.10 , pp. 702-709
    • Connors, T.A.1
  • 10
    • 0029102762 scopus 로고
    • Prodrugs in cancer chemotherapy
    • Connors TA, Knox RJ (1995) Prodrugs in cancer chemotherapy. Stem Cells 13:501-511
    • (1995) Stem Cells , vol.13 , pp. 501-511
    • Connors, T.A.1    Knox, R.J.2
  • 11
    • 33751419875 scopus 로고    scopus 로고
    • Nanomedicine: Developing smarter therapeutic and diagnostic modalities
    • DOI 10.1016/j.addr.2006.09.011, PII S0169409X06001736, Particulate Nanomedicines
    • Farokhzad OC, Langer R (2006) Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv Drug Deliv Rev 58:1456-1459 (Pubitemid 44820502)
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.14 , pp. 1456-1459
    • Farokhzad, O.C.1    Langer, R.2
  • 12
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: Opportunities and challenges
    • DOI 10.1038/nrc1566
    • Ferrari M (2005) Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 5:161-171 (Pubitemid 40314948)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 161-171
    • Ferrari, M.1
  • 13
    • 1642340731 scopus 로고    scopus 로고
    • A set of surface-modified dendrimers with potential application as drug delivery vehicles: Synthesis in vitro cytotoxicity, and intracellular localization
    • Fuchs S, Kapp T, Otto H, Schoneberg T, Franke P, Gust R, Schlüter AD (2004) A set of surface-modified dendrimers with potential application as drug delivery vehicles: synthesis, in vitro cytotoxicity, and intracellular localization. Chemistry 10:1167-1192
    • (2004) Chemistry , vol.10 , pp. 1167-1192
    • Fuchs, S.1    Kapp, T.2    Otto, H.3    Schoneberg, T.4    Franke, P.5    Gust, R.6    Schlüter, A.D.7
  • 14
    • 0018408147 scopus 로고
    • 2 UND 2,2'-AZINO-DI-(3-ETHYL- BENZTHIAZOLINSULFONSAURE(6) (ABTS)
    • Gallati H (1979) Horseradish peroxidase: a study of the kinetics and the determination of optimal reaction conditions, using hydrogen peroxide and 2, 2-azinobis 3-ethylbenzthiazo-line-6-sulfonic acid (ABTS) as substrates. J Clin Chem Clin Biochem 17:1-7 (Pubitemid 9081123)
    • (1979) Journal of Clinical Chemistry and Clinical Biochemistry , vol.17 , Issue.1 , pp. 1-7
    • Gallati, H.1
  • 15
    • 0032127175 scopus 로고    scopus 로고
    • Identification of skatolyl hydroperoxide and its role in the peroxidase-catalysed oxidation of indol-3-yl acetic acid
    • Gazarian IG, Lagrimini LM, Mellon FA, Naldrett MJ, Ashby GA, Thorneley RN (1998) Identification of skatolyl hydroperoxide and its role in the peroxidase-catalysed oxidation of indol-3-yl acetic acid. Biochem J 333:223-232 (Pubitemid 28342513)
    • (1998) Biochemical Journal , vol.333 , Issue.1 , pp. 223-232
    • Gazarian, I.G.1    Lagrimini, L.M.2    Mellon, F.A.3    Naldrett, M.J.4    Ashby, G.A.5    Thorneley, R.N.F.6
  • 17
    • 33845229315 scopus 로고    scopus 로고
    • Enzymatic activation of second-generation dendritic prodrugs: Conjugation of self-immolative dendrimers with poly(ethylene glycol) via click chemistry
    • DOI 10.1021/bc060180n
    • Gopin A, Ebner S, Attali B, Shabat D (2006) Enzymatic activation of second-generation dendritic prodrugs: conjugation of self-immolative dendrimers with poly (ethylene glycol) via click chemistry. Bioconj Chem 17:1432-1440 (Pubitemid 44851487)
    • (2006) Bioconjugate Chemistry , vol.17 , Issue.6 , pp. 1432-1440
    • Gopin, A.1    Ebner, S.2    Attali, B.3    Shabat, D.4
  • 18
    • 0036005974 scopus 로고    scopus 로고
    • UPA-Silica-Particles (SP-uPA): A novel analytical system to investigate uPA-uPAR interaction and to test synthetic uPAR antagonists as potential cancer therapeutics
    • DOI 10.1515/BC.2002.021
    • Guthaus E, Burgle M, Schmiedeberg N, Hocke S, Eickler A, Kramer MD, Sweep CG, Magdolen V et al (2002) uPA-silica-particles (SP-uPA): a novel analytical system to investigate uPA-uPAR interaction and to test synthetic uPAR antagonists as potential cancer therapeutics. Biol Chem 383:207-216 (Pubitemid 34224043)
    • (2002) Biological Chemistry , vol.383 , Issue.1 , pp. 207-216
    • Guthaus, E.1    Burgle, M.2    Schmiedeberg, N.3    Hocke, S.4    Eickler, A.5    Kramer, M.D.6    Sweep, C.G.J.F.7    Magdolen, V.8    Kessler, H.9    Schmitt, M.10
  • 19
    • 0042143281 scopus 로고    scopus 로고
    • Targeted prodrug design to optimize drug delivery
    • Han HK, Amidon GL (2000) Targeted prodrug design to optimize drug delivery. AAPS PharmSci 2:E6
    • (2000) AAPS PharmSci , vol.2
    • Han, H.K.1    Amidon, G.L.2
  • 20
    • 0141839804 scopus 로고    scopus 로고
    • Selective activation of anthracycline prodrugs for use in conjunction with ADEPT
    • DOI 10.1358/dnp.2003.16.5.829319
    • Hari Krishna D, Rao AR, Krishna DR (2003) Selective activation of anthracycline prodrugs for use in conjunction with ADEPT. Drug News Perspect 16:309-318 (Pubitemid 37176219)
    • (2003) Drug News and Perspectives , vol.16 , Issue.5 , pp. 309-318
    • HariKrishna, D.1    Rao, A.R.R.2    Krishna, D.R.3
  • 21
    • 15844369555 scopus 로고    scopus 로고
    • A comparative study of the purity, enzyme activity, and inactivation by hydrogen peroxide of commercially available horseradish peroxidase isoenzymes A and C
    • DOI 10.1002/(SICI)1097-0290(199 60620)50:6<6 55::AID-BIT6>3.0.CO;2- J
    • Hiner ANP, Hernández-Ruíz J, Amao MB, García- Cánovas F, Acosta M (1996) A comparative study of the purity, enzyme activity, and inactivation by hydrogen peroxide of commercially available horseradish peroxidase isoen-zymes A and C. Biotechnol Bioeng 50:655-662 (Pubitemid 26152238)
    • (1996) Biotechnology and Bioengineering , vol.50 , Issue.6 , pp. 655-662
    • Hiner, A.N.P.1    Hernandez-Ruiz, J.2    Arnao, M.B.3    Garcia-Canovas, F.4    Acosta, M.5
  • 22
    • 0000793141 scopus 로고
    • Peroxidase-catalyzed oxidation of indole-3-acetic acid
    • Hinman RL, Lang J (1965) Peroxidase-catalyzed oxidation of indole-3-acetic acid. Biochemistry 4:144-158
    • (1965) Biochemistry , vol.4 , pp. 144-158
    • Hinman, R.L.1    Lang, J.2
  • 23
    • 33745727965 scopus 로고    scopus 로고
    • 2-poly (dimethylsiloxane) hybrid material in the fabrication of amperometric biosensor
    • 2-poly (dimethylsiloxane) hybrid material in the fabrication of amperometric biosensor. Anal Chim Acta 572:248-252
    • (2006) Anal Chim Acta , vol.572 , pp. 248-252
    • Ho, W.-J.1    Yuan, C.-J.2    Reiko, O.3
  • 24
    • 83755207342 scopus 로고    scopus 로고
    • A review of the current scientific and regulatory status of nanomedicines and the challenges ahead
    • Hock SC, Ying YM, Wah CL (2011) A review of the current scientific and regulatory status of nanomedicines and the challenges ahead. PDA J Pharm Sci Technol 65:177-195
    • (2011) PDA J Pharm Sci Technol , vol.65 , pp. 177-195
    • Hock, S.C.1    Ying, Y.M.2    Wah, C.L.3
  • 25
    • 11844276570 scopus 로고    scopus 로고
    • Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules
    • DOI 10.1016/j.jconrel.2004.10.002, PII S0168365904004742
    • Huysmans G, Ranquin A, Wyns L, Steyaert J, Van Gelder P (2005) Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules.JControl Release 102:171-179 (Pubitemid 40093783)
    • (2005) Journal of Controlled Release , vol.102 , Issue.1 , pp. 171-179
    • Huysmans, G.1    Ranquin, A.2    Wyns, L.3    Steyaert, J.4    Van Gelder, P.5
  • 26
    • 30344452028 scopus 로고    scopus 로고
    • Bone implants - A challenge to materials science
    • Karlsson KH (1999) Bone implants-a challenge to materials science. Ann Chir Gynaecol 88:226-235 (Pubitemid 29472819)
    • (1999) Annales Chirurgiae et Gynaecologiae , vol.88 , Issue.3 , pp. 226-235
    • Karlsson, K.H.1
  • 27
    • 0026085938 scopus 로고
    • Effects of injecting massive amounts of bioactive ceramics in mice
    • Kawanabe K, Yamamuro T, Nakamura T, Kotani S (1991) Effects of injecting massive amounts of bioactive ceramics in mice. J Biomed Mater Res 25:117-1128
    • (1991) J Biomed Mater Res , vol.25 , pp. 117-1128
    • Kawanabe, K.1    Yamamuro, T.2    Nakamura, T.3    Kotani, S.4
  • 28
    • 0242321121 scopus 로고    scopus 로고
    • Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells
    • Kim DS, Jeon SE, Park KC (2004) Oxidation of indole-3-acetic acid by horseradish peroxidase induces apoptosis in G361 human melanoma cells. Cell Signal 16:81-88
    • (2004) Cell Signal , vol.16 , pp. 81-88
    • Kim, D.S.1    Jeon, S.E.2    Park, K.C.3
  • 29
    • 0001637735 scopus 로고
    • Analysis of the stable end products and intermediates of oxidative decarboxylation of indole-3-acetic acid by horseradish peroxidase
    • Kobayashi S, Sugioka K, Nakano H, Nakano M, Tero-Kubota S (1984) Analysis of the stable end products and intermediates of oxidative decarboxylation of indole-3-acetic acid by horseradish peroxidase. Biochemistry 23:4589-4597
    • (1984) Biochemistry , vol.23 , pp. 4589-4597
    • Kobayashi, S.1    Sugioka, K.2    Nakano, H.3    Nakano, M.4    Tero-Kubota, S.5
  • 31
    • 0034738791 scopus 로고    scopus 로고
    • Influence of process parameters on the protein stability encapsulated in poly-DL-lactide-poly(ethylene glycol) microspheres
    • DOI 10.1016/S0168-3659(00)00235-2, PII S0168365900002352
    • Li X, Zhang Y, Yan R, Jia W, Yuan M, Deng X, Huang Z (2000) Influence of process parameters on the protein stability encapsulated in poly-DL-lactide-poly (ethylene glycol) microspheres. J Control Release 68:41-52 (Pubitemid 30407060)
    • (2000) Journal of Controlled Release , vol.68 , Issue.1 , pp. 41-52
    • Li, X.1    Zhang, Y.2    Yan, R.3    Jia, W.4    Yuan, M.5    Deng, X.6    Huang, Z.7
  • 32
    • 0024047692 scopus 로고
    • Dynamics of growth of silica particles from ammonia-catalyzed hydrolysis of tetra-ethyl-orthosilicate
    • DOI 10.1016/0021-9797(88)90346-3
    • Matsoukas T, Gulari E (1988) Dynamics of growth of silica particles from ammonia-catalyzed hydrolysis of tetra-ethyl-orthosilicate. J Colloid Interface Sci 124:252-261 (Pubitemid 18660164)
    • (1988) Journal of Colloid and Interface Science , vol.124 , Issue.1 , pp. 252-261
    • Matsoukas, T.1    Gulari Erdogan2
  • 33
    • 0028090161 scopus 로고
    • Self-immolative prodrugs: Candidates for antibody-directed enzyme prodrug therapy in conjunction with a nitroreductase enzyme
    • DOI 10.1021/jm00047a002
    • Mauger AB, Burke PJ, Somani HH, Friedlos F, Knox RJ (1994) Self-immolative prodrugs: candidates for antibody-directed enzyme prodrug therapy in conjunction with a nitro-reductase enzyme. J Med Chem 37:3452-3458 (Pubitemid 24334600)
    • (1994) Journal of Medicinal Chemistry , vol.37 , Issue.21 , pp. 3452-3458
    • Mauger, A.B.1    Burke, P.J.2    Somani, H.H.3    Friedlos, F.4    Knox, R.J.5
  • 34
    • 0141538137 scopus 로고    scopus 로고
    • Enzyme/abzyme prodrug activation systems: Potential use in clinical oncology
    • DOI 10.2174/1381612033454063
    • Nishi Y (2003) Enzyme/abzyme prodrug activation systems: potential use in clinical oncology. Curr Pharm Des 9: 2113-2130 (Pubitemid 37139088)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.26 , pp. 2113-2130
    • Nishi, Y.1
  • 35
    • 0037016811 scopus 로고    scopus 로고
    • Preparation of silica nanoparticles: Determination of the optimal synthesis conditions for small and uniform particles
    • DOI 10.1016/S0927-7757(01)00683-5, PII S0927775701006835
    • Park SK, Kim KD, Kim HT (2002) Preparation of silica nano-particles: determination of the optimal synthesis conditions for small and uniform particles. Colloids Surf A Physico-chem Eng Aspects 197:7-17 (Pubitemid 34017362)
    • (2002) Colloids and Surfaces A: Physicochemical and Engineering Aspects , vol.197 , Issue.1-3 , pp. 7-17
    • Park, S.K.1    Kim, K.D.2    Kim, H.T.3
  • 36
    • 10044290777 scopus 로고    scopus 로고
    • Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells
    • DOI 10.1016/j.biomaterials.2004.07.023, PII S0142961204006763
    • Petri-Fink A, Chastellain M, Juillerat-Jeanneret L, Ferrari A, Hofmann H (2005) Development of functionalized super-paramagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials 26:2685-2694 (Pubitemid 39600721)
    • (2005) Biomaterials , vol.26 , Issue.15 , pp. 2685-2694
    • Petri-Fink, A.1    Chastellain, M.2    Juillerat-Jeanneret, L.3    Ferrari, A.4    Hofmann, H.5
  • 37
    • 0034880727 scopus 로고    scopus 로고
    • Biochemically functionalized silica nanoparticles
    • DOI 10.1039/b101489g
    • Qhobosheane M, Santra S, Zhang P, Tan W (2001) Biochemically functionalized silica nanoparticles. Analyst 126: 1274-1278 (Pubitemid 32747743)
    • (2001) Analyst , vol.126 , Issue.8 , pp. 1274-1278
    • Qhobosheane, M.1    Santra, S.2    Zhang, P.3    Tan, W.4
  • 38
    • 0033791439 scopus 로고    scopus 로고
    • Reactivity of horseradish per-oxidase compound II toward substrates: Kinetic evidence for a two-step mechanism
    • Rodriguez-López JN, Gilabert MA, Tudela J, Thorneley RN, Garcia-Cánovas F (2000) Reactivity of horseradish per-oxidase compound II toward substrates: kinetic evidence for a two-step mechanism. Biochemistry 39:13201-13209
    • (2000) Biochemistry , vol.39 , pp. 13201-13209
    • Rodriguez-López, J.N.1    Gilabert, M.A.2    Tudela, J.3    Thorneley, R.N.4    Garcia-Cánovas, F.5
  • 39
    • 0028959387 scopus 로고
    • Coupled-column liquid chromatographic analysis of epirubicin and metabolites in biological material and its application to optimization of liver cancer therapy
    • Rudolphi A, Vielhauer S, Boos KS, Seidel D, Bathge IM, Berger H (1995) Coupled-column liquid chromatographic analysis of epirubicin and metabolites in biological material and its application to optimization of liver cancer therapy. J Pharm Biomed Anal 13:615-623
    • (1995) J Pharm Biomed Anal , vol.13 , pp. 615-623
    • Rudolphi, A.1    Vielhauer, S.2    Boos, K.S.3    Seidel, D.4    Bathge, I.M.5    Berger, H.6
  • 41
    • 0020494564 scopus 로고
    • Oxidation of indole-3-acetic acid by peroxidase: Involvement of reduced peroxidase and compound III with superoxide as a product
    • Smith AM, Morrison WL, Milham PJ (1982) Oxidation of indole-3-acetic acid by peroxidase: involvement of reduced peroxidase and compound III with superoxide as a product. Biochemistry 21:4414-4419
    • (1982) Biochemistry , vol.21 , pp. 4414-4419
    • Smith, A.M.1    Morrison, W.L.2    Milham, P.J.3
  • 42
    • 0032897384 scopus 로고    scopus 로고
    • Antibody directed enzyme prodrug therapy (ADEPT): A review of the experimental and clinical considerations
    • Syrigos KN, Epenetos AA (1999) Antibody directed enzyme prodrug therapy (ADEPT): a review of the experimental and clinical considerations. Anticancer Res 19:605-613 (Pubitemid 29168301)
    • (1999) Anticancer Research , vol.19 , Issue.1 A , pp. 605-613
    • Syrigos, K.N.1    Epenetos, A.A.2
  • 43
    • 58149408528 scopus 로고
    • Preparation and characterization of spherical monodisperse silica dispersions in nonaqueous solvents
    • Van Helden AK, Jansen JW, Vrij A (1981) Preparation and characterization of spherical monodisperse silica dispersions in nonaqueous solvents. J Colloid Interface Sci 81: 354-368
    • (1981) J Colloid Interface Sci , vol.81 , pp. 354-368
    • Van Helden, A.K.1    Jansen, J.W.2    Vrij, A.3
  • 44
    • 0036015564 scopus 로고    scopus 로고
    • Indole-3-acetic acids and horseradish peroxidase: A new prodrug/enzyme combination for targeted cancer therapy
    • DOI 10.2174/1381612023394610
    • Wardman P (2002) Indole-3-acetic acids and horseradish per-oxidase: a new prodrug/enzyme combination for targeted cancer therapy. Curr Pharm Res 8:1363-1374 (Pubitemid 34591352)
    • (2002) Current Pharmaceutical Design , vol.8 , Issue.15 , pp. 1363-1374
    • Wardman, P.1
  • 45
    • 44249089305 scopus 로고    scopus 로고
    • Characterization of secondary and tertiary conformational changes of β-lactoglobulin adsorbed on silica nanoparticle surfaces
    • DOI 10.1021/la703349c
    • Wu X, Narsimha G (2008) Characterization of secondary and tertiary conformational changes of beta-lactoglobulin adsorbed on silica nanoparticle surfaces. Langmuir 24: 4989-4998 (Pubitemid 351725189)
    • (2008) Langmuir , vol.24 , Issue.9 , pp. 4989-4998
    • Wu, X.1    Narsimhan, G.2
  • 46
    • 0028415423 scopus 로고
    • Oxidation of dibenzothiophene catalyzed by heme-containing enzymes encapsulated in sol-gel glass. A new form of biocatalysts
    • Wu S, Lin J, Chan SI (1994) Oxidation of dibenzothiophene catalyzed by heme-containing enzymes encapsulated in sol-gel glass. A new form of biocatalysts. Appl Biochem Biotechnol 47:11-20
    • (1994) Appl Biochem Biotechnol , vol.47 , pp. 11-20
    • Wu, S.1    Lin, J.2    Chan, S.I.3


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