Ligation tunes protein reactivity in an ancient haemoglobin: Kinetic evidence for an allosteric mechanism in methanosarcina acetivorans protoglobin

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Abbruzzetti, Stefania ^a,b   Tilleman, Lesley ^c   Bruno, Stefano ^a   Viappiani, Cristiano ^a,b   Desmet, Filip ^c   van Doorslaer, Sabine ^c   Coletta, Massimo ^d,e   Ciaccio, Chiara ^d,e   Ascenzi, Paolo ^f   Nardini, Marco ^g   Bolognesi, Martino ^g   Moens, Luc ^c   Dewilde, Sylvia ^c  

^a UNIVERSITY OF PARMA   (Italy)

^b ISTITUTO NANOSCIENZE CNR   (Italy)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

^e Consorzio Interuniversitario di Ricerca in Chimica dei Metalli nei Sistemi Biologici ^*  (Italy)

^f ROMA TRE UNIVERSITY   (Italy)

^g UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLOBIN; PROTOGLOBIN PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CARBONYLATION; CELL KINETICS; CONTROLLED STUDY; DISSOCIATION; ENZYME REACTIVATION; HEMOGLOBIN ANALYSIS; METHANOSARCINA ACETIVORANS; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS;

ALLOSTERIC REGULATION; ARCHAEAL PROTEINS; CARBON MONOXIDE; FERROUS COMPOUNDS; GLOBINS; HEMOGLOBINS; KINETICS; METHANOSARCINA; PHOTOLYSIS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS;

METHANOSARCINA ACETIVORANS;

EID: 84858958591     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033614     Document Type: Article

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