메뉴 건너뛰기




Volumn 54, Issue 1, 2012, Pages 11-28

Pulmonary hypertension in 2012: Contemporary issues in diagnosis and management

Author keywords

Hypertension; Pulmonary ; Pulmonary arterial hypertension ; Vasodilator agents

Indexed keywords

ANTIHYPERTENSIVE AGENT;

EID: 84858853407     PISSN: 00310808     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (130)
  • 1
    • 77956396934 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: From the kingdom of the near-dead to multiple clinical trial metaanalyses
    • Galiè N, Palazzini M, Manes A. Pulmonary arterial hypertension: from the kingdom of the near-dead to multiple clinical trial metaanalyses. Eur Heart J 2010;31:2080-6.
    • (2010) Eur Heart J , vol.31 , pp. 2080-2086
    • Galiè, N.1    Palazzini, M.2    Manes, A.3
  • 2
    • 70049112901 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary
    • Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT).
    • Galiè N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 2009;30:2493-537.
    • (2009) Eur Heart J , vol.30 , pp. 2493-2537
    • Galiè, N.1    Hoeper, M.M.2    Humbert, M.3    Torbicki, A.4    Vachiery, J.L.5    Barbera, J.A.6
  • 3
    • 78349268378 scopus 로고    scopus 로고
    • Pulmonary hypertension and pulmonary arterial hypertension: A clarification is needed
    • Galie N, Palazzini M, Manes A. Pulmonary hypertension and pulmonary arterial hypertension: a clarification is needed. Eur Respir J 2010;36:986-90.
    • (2010) Eur Respir J , vol.36 , pp. 986-990
    • Galie, N.1    Palazzini, M.2    Manes, A.3
  • 4
    • 67649579669 scopus 로고    scopus 로고
    • Updated clinical classification of pulmonary hypertension
    • Simonneau G, Robbins IM, Beghetti M, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2009;54:S43-54.
    • (2009) J Am Coll Cardiol , vol.54
    • Simonneau, G.1    Robbins, I.M.2    Beghetti, M.3
  • 5
    • 66549127501 scopus 로고    scopus 로고
    • ACCF/AHA 2009 expert consensus document on pulmonary hypertension: A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association
    • developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association.
    • McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation 2009; 119:2250-94.
    • (2009) Circulation , vol.119 , pp. 2250-2294
    • McLaughlin, V.V.1    Archer, S.L.2    Badesch, D.B.3    Barst, R.J.4    Farber, H.W.5    Lindner, J.R.6
  • 7
    • 64849109410 scopus 로고    scopus 로고
    • ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus
    • Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association.
    • McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. J Am Coll Cardiol 2009;53:1573-619.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1573-1619
    • McLaughlin, V.V.1    Archer, S.L.2    Badesch, D.B.3    Barst, R.J.4    Farber, H.W.5    Lindner, J.R.6
  • 8
    • 78649821027 scopus 로고    scopus 로고
    • Exercise-induced pulmonary hypertension associated with systemic sclerosis: Four distinct entities
    • Saggar R, Khanna D, Furst DE, Shapiro S, Maranian P, Belperio JA et al. Exercise-induced pulmonary hypertension associated with systemic sclerosis: four distinct entities. Arthritis Rheum 2010;62:3741-50.
    • (2010) Arthritis Rheum , vol.62 , pp. 3741-3750
    • Saggar, R.1    Khanna, D.2    Furst, D.E.3    Shapiro, S.4    Maranian, P.5    Belperio, J.A.6
  • 10
    • 73449084124 scopus 로고    scopus 로고
    • Long-term outcome in pulmonary arterial hypertension: A plea for earlier parenteral prostacyclin therapy
    • Delcroix M, Spaas K, Quarck R. Long-term outcome in pulmonary arterial hypertension: a plea for earlier parenteral prostacyclin therapy. Eur Respir Rev 2009;18:253-9.
    • (2009) Eur Respir Rev , vol.18 , pp. 253-259
    • Delcroix, M.1    Spaas, K.2    Quarck, R.3
  • 11
    • 79958717109 scopus 로고    scopus 로고
    • Integration of clinical and hemodynamic parameters in the prediction of long-term survival in patients with pulmonary arterial hypertension
    • Kane GC, Maradit-Kremers H, Slusser JP, Scott CG, Frantz RP, McGoon MD. Integration of clinical and hemodynamic parameters in the prediction of long-term survival in patients with pulmonary arterial hypertension. Chest 2011;139:1285-93.
    • (2011) Chest , vol.139 , pp. 1285-1293
    • Kane, G.C.1    Maradit-Kremers, H.2    Slusser, J.P.3    Scott, C.G.4    Frantz, R.P.5    McGoon, M.D.6
  • 12
    • 45249119855 scopus 로고    scopus 로고
    • Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): A double-blind, randomised controlled trial
    • DOI 10.1016/S0140-6736(08)60919-8, PII S0140673608609198
    • Galie N, Rubin L, Hoeper M, Jansa P, Al-Hiti H, Meyer G et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 2008;371:2093-100. (Pubitemid 351902178)
    • (2008) The Lancet , vol.371 , Issue.9630 , pp. 2093-2100
    • Galie, N.1    Rubin, L.2    Hoeper, M.3    Jansa, P.4    Al-Hiti, H.5    Meyer, G.6    Chiossi, E.7    Kusic-Pajic, A.8    Simonneau, G.9
  • 14
    • 79960103454 scopus 로고    scopus 로고
    • Delay in recognition of pulmonary arterial hypertension: Factors identified from the REVEAL Registry
    • Brown LM, Chen H, Halpern S, Taichman D, McGoon MD, Farber HW et al. Delay in recognition of pulmonary arterial hypertension: factors identified from the REVEAL Registry. Chest 2011;140:19-26.
    • (2011) Chest , vol.140 , pp. 19-26
    • Brown, L.M.1    Chen, H.2    Halpern, S.3    Taichman, D.4    McGoon, M.D.5    Farber, H.W.6
  • 15
    • 79960420756 scopus 로고    scopus 로고
    • The early diagnosis of pulmonary arterial hypertension: Can we do better?
    • Paleviky HI. The early diagnosis of pulmonary arterial hypertension: can we do better? Chest 2011;140:4-6.
    • (2011) Chest , vol.140 , pp. 4-6
    • Paleviky, H.I.1
  • 16
    • 34249784805 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension in systemic sclerosis: The need for early detection and treatment
    • DOI 10.1111/j.1445-5994.2007.01370.x
    • Proudman SM, Stevens WM, Sahhar J, Celermajer D. Pulmonary arterial hypertension in systemic sclerosis: the need for early detection and treatment. Intern Med J 2007;37:485-94. (Pubitemid 46855082)
    • (2007) Internal Medicine Journal , vol.37 , Issue.7 , pp. 485-494
    • Proudman, S.M.1    Stevens, W.M.2    Sahhar, J.3    Celermajer, D.4
  • 17
    • 82955235654 scopus 로고    scopus 로고
    • Pulmonary hypertension: Screening and evaluation in scleroderma
    • York M, Farber HW. Pulmonary hypertension: screening and evaluation in scleroderma. Curr Opin Rheumatol 2011;23:536-44.
    • (2011) Curr Opin Rheumatol , vol.23 , pp. 536-544
    • York, M.1    Farber, H.W.2
  • 18
    • 70049117716 scopus 로고    scopus 로고
    • Screening for pulmonary arterial hypertension in systemic sclerosis
    • Vachiery JL, Coghlan G. Screening for pulmonary arterial hypertension in systemic sclerosis. Eur Respir Rev 2009;18:162-9.
    • (2009) Eur Respir Rev , vol.18 , pp. 162-169
    • Vachiery, J.L.1    Coghlan, G.2
  • 19
    • 14944346766 scopus 로고    scopus 로고
    • Screening for pulmonary hypertension in systemic sclerosis: The longitudinal development of tricuspid gradient in 227 consecutive patients, 1992-2001
    • DOI 10.1093/rheumatology/keh486
    • Hesselstrand R, Ekman R, Eskilsson J, Isaksson A, Scheja A, Ohlin AK et al. Screening for pulmonary hypertension in systemic sclerosis: the longitudinal development of tricuspid gradient in 227 consecutive patients, 1992-2001. Rheumatology (Oxford) 2005;44:366-71. (Pubitemid 40361295)
    • (2005) Rheumatology , vol.44 , Issue.3 , pp. 366-371
    • Hesselstrand, R.1    Ekman, R.2    Eskilsson, J.3    Isaksson, A.4    Scheja, A.5    Ohlin, A.-K.6    Akesson, A.7
  • 20
    • 3142692425 scopus 로고    scopus 로고
    • Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • DOI 10.1378/chest.126.1-suppl.14S
    • McGoon M, Gutterman D, Steen V, Barst R, McCrory DC, Fortin TA et al. Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 2004;126:14S-34S. (Pubitemid 38932340)
    • (2004) Chest , vol.126 , Issue.SUPPL.1
    • McGoon, M.1    Gutterman, D.2    Steen, V.3    Barst, R.4    McCrory, D.C.5    Fortin, T.A.6    Loyd, J.E.7
  • 23
    • 70350110402 scopus 로고    scopus 로고
    • Prevalence of pulmonary arterial hypertension in an Australian scleroderma population: Screening allows for earlier diagnosis
    • Phung S, Strange G, Chung LP, Leong J, Dalton B, Roddy J et al. Prevalence of pulmonary arterial hypertension in an Australian scleroderma population: screening allows for earlier diagnosis. Intern Med J 2009;39:682-91.
    • (2009) Intern Med J , vol.39 , pp. 682-691
    • Phung, S.1    Strange, G.2    Chung, L.P.3    Leong, J.4    Dalton, B.5    Roddy, J.6
  • 26
    • 80155127921 scopus 로고    scopus 로고
    • Screening for pulmonary arterial hypertension in patients with systemic sclerosis: Clinical characteristics at diagnosis and longterm survival
    • Humbert M, Yaici A, de Groote P, Montani D, Sitbon O, Launay D et al. Screening for pulmonary arterial hypertension in patients with systemic sclerosis: Clinical characteristics at diagnosis and longterm survival. Arthritis Rheum 2011;63:3522-30
    • (2011) Arthritis Rheum , vol.63 , pp. 3522-3530
    • Humbert, M.1    Yaici, A.2    De Groote, P.3    Montani, D.4    Sitbon, O.5    Launay, D.6
  • 27
    • 80155206329 scopus 로고    scopus 로고
    • Improving the detection of pulmonary hypertension in systemic sclerosis using pulmonary function tests
    • Schreiber BE, Valerio CJ, Keir GJ, Handler C, Wells AU, Denton CP et al. Improving the detection of pulmonary hypertension in systemic sclerosis using pulmonary function tests. Arthritis Rheum 2011;63:3531-9
    • (2011) Arthritis Rheum , vol.63 , pp. 3531-3539
    • Schreiber, B.E.1    Valerio, C.J.2    Keir, G.J.3    Handler, C.4    Wells, A.U.5    Denton, C.P.6
  • 29
    • 79955785234 scopus 로고    scopus 로고
    • Inaccuracy of Doppler echocardiographic estimates of pulmonary artery pressures in patients with pulmonary hypertension: Implications for clinical practice
    • Rich JD, Shah SJ, Swamy RS, Kamp A, Rich S. Inaccuracy of Doppler echocardiographic estimates of pulmonary artery pressures in patients with pulmonary hypertension: implications for clinical practice. Chest 2011; 139:988-93.
    • (2011) Chest , vol.139 , pp. 988-993
    • Rich, J.D.1    Shah, S.J.2    Swamy, R.S.3    Kamp, A.4    Rich, S.5
  • 32
    • 79960101398 scopus 로고    scopus 로고
    • A hemodynamic study of pulmonary hypertension in sickle cell disease
    • Parent F, Bachir D, Inamo J, Lionnet F, Driss F, Loko G, et al. A hemodynamic study of pulmonary hypertension in sickle cell disease. N Engl J Med 2011;365:44-53.
    • (2011) N Engl J Med , vol.365 , pp. 44-53
    • Parent, F.1    Bachir, D.2    Inamo, J.3    Lionnet, F.4    Driss, F.5    Loko, G.6
  • 34
    • 78651245213 scopus 로고    scopus 로고
    • In defence of exercise stress tests for the diagnosis of pulmonary hypertension
    • Neije R. In defence of exercise stress tests for the diagnosis of pulmonary hypertension. Heart 2011;97:94-5.
    • (2011) Heart , vol.97 , pp. 94-95
    • Neije, R.1
  • 35
    • 73449137534 scopus 로고    scopus 로고
    • Letter by Neije and Melot regarding article, "Exercise-induced pulmonary arterial hypertension"
    • author reply e4
    • Neije R, Melot C. Letter by Neije and Melot regarding article, "Exercise-induced pulmonary arterial hypertension". Circulation 2009;120:e283; author reply e4.
    • (2009) Circulation , vol.120
    • Neije, R.1    Melot, C.2
  • 36
    • 57449106650 scopus 로고    scopus 로고
    • Exercise-induced pulmonary arterial hypertension: A new addition to the spectrum of pulmonary vascular diseases
    • Oudiz RJ, Rubin LI. Exercise-induced pulmonary arterial hypertension: a new addition to the spectrum of pulmonary vascular diseases. Circulation 2008; 118:2120-1.
    • (2008) Circulation , vol.118 , pp. 2120-2121
    • Oudiz, R.J.1    Rubin, L.I.2
  • 37
    • 33750031478 scopus 로고    scopus 로고
    • Abnormal pulmonary vascular responses in patients registered with a systemic autoimmunity database: Pulmonary Hypertension Assessment and Screening Evaluation using stress echocardiography (PHASE-I)
    • DOI 10.1016/j.euje.2005.12.002, PII S1525216705002295
    • Collins N, Bastian B, Quiqueree L, Jones C, Morgan R, Reeves G. Abnormal pulmonary vascular responses in patients registered with a systemic autoimmunity database: Pulmonary Hypertension Assessment and Screening Evaluation using stress echocardiography (PHASE-I). Eur J Echocardiogr 2006;7:439-46. (Pubitemid 44645060)
    • (2006) European Journal of Echocardiography , vol.7 , Issue.6 , pp. 439-446
    • Collins, N.1    Bastian, B.2    Quiqueree, L.3    Jones, C.4    Morgan, R.5    Reeves, G.6
  • 38
    • 65349136490 scopus 로고    scopus 로고
    • Stress Doppler echocardiography in relatives of patients with idiopathic and familial pulmonary arterial hypertension: Results of a multicenter European analysis of pulmonary artery pressure response to exercise and hypoxia
    • Grunig E, Weissmann S, Ehlken N, Fijalkowska A, Fischer C, Fourme T et al. Stress Doppler echocardiography in relatives of patients with idiopathic and familial pulmonary arterial hypertension: results of a multicenter European analysis of pulmonary artery pressure response to exercise and hypoxia. Circulation 2009; 119:1747-57.
    • (2009) Circulation , vol.119 , pp. 1747-1757
    • Grunig, E.1    Weissmann, S.2    Ehlken, N.3    Fijalkowska, A.4    Fischer, C.5    Fourme, T.6
  • 39
    • 47549101707 scopus 로고    scopus 로고
    • Exercise-induced pulmonary arterial hypertension in patients with systemic sclerosis
    • DOI 10.1378/chest.07-2324
    • Steen V, Chou M, Shanmugam V, Mathias M, Kuru T, Morrissey R. Exercise-induced pulmonary arterial hypertension in patients with systemic sclerosis. Chest 2008;134:146-51. (Pubitemid 352008776)
    • (2008) Chest , vol.134 , Issue.1 , pp. 146-151
    • Steen, V.1    Chou, M.2    Shanmugam, V.3    Mathias, M.4    Kuru, T.5    Morrissey, R.6
  • 43
    • 78650844890 scopus 로고    scopus 로고
    • Is exercise-induced pulmonary hypertension ready for prime time in systemic sclerosis?
    • Steen VD, Champion H. Is exercise-induced pulmonary hypertension ready for prime time in systemic sclerosis? Int J Clin Pract Suppl 2011:1-3.
    • (2011) Int J Clin Pract Suppl , pp. 1-3
    • Steen, V.D.1    Champion, H.2
  • 44
    • 67649624517 scopus 로고    scopus 로고
    • Pulmonary arterial pressure during rest and exercise in healthy subjects: A systematic review
    • Kovacs G, Berghold A, Scheidl S, Olschewski H. Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review. Eur Respir J 2009;34:888-94.
    • (2009) Eur Respir J , vol.34 , pp. 888-894
    • Kovacs, G.1    Berghold, A.2    Scheidl, S.3    Olschewski, H.4
  • 47
    • 78049287670 scopus 로고    scopus 로고
    • Pulmonary hypertension with left-sided heart disease
    • Guazzi M, Arena R. Pulmonary hypertension with left-sided heart disease. Nat Rev Cardiol 2010;7:648-59.
    • (2010) Nat Rev Cardiol , vol.7 , pp. 648-659
    • Guazzi, M.1    Arena, R.2
  • 50
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • The Primary Pulmonary Hypertension Study Group
    • Barst RJ, Rubin U, Long WA, McGoon MD, Rich S, Badesch DB et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med 1996;334:296-302.
    • (1996) N Engl J Med , vol.334 , pp. 296-302
    • Barst, R.J.1    Rubin, U.2    Long, W.A.3    McGoon, M.D.4    Rich, S.5    Badesch, D.B.6
  • 58
    • 1842530387 scopus 로고    scopus 로고
    • Clinical efficacy of sildenafil in primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
    • DOI 10.1016/j.jacc.2003.10.056, PII S0735109704001056
    • Sastry BKS, Narasimhan C, Reddy NK, Raju BS. Clinical efficacy of sildenafil in primary pulmonary hypertension. 1 : A randomized, placebo-controlled, double- blind, crossover study. J Am Coll Cardiol 2004;43:1149-53. (Pubitemid 38452588)
    • (2004) Journal of the American College of Cardiology , vol.43 , Issue.7 , pp. 1149-1153
    • Sastry, B.K.S.1    Narasimhan, C.2    Reddy, N.K.3    Raju, B.S.4
  • 60
    • 33645230584 scopus 로고    scopus 로고
    • Randomized, placebo- Controlled, double-blind, crossover study to evaluate the efficacy of oral sildenafil therapy in severe pulmonary artery hypertension
    • e1 -851 .e5
    • Singh T, Rohit M, Grover A, Malhotra S, Vijayvergiya R. A randomized, placebo- controlled, double-blind, crossover study to evaluate the efficacy of oral sildenafil therapy in severe pulmonary artery hypertension. Am Heart J 2006; 151:851 .e1 -851 .e5.
    • (2006) Am Heart J , vol.151 , pp. 851
    • Singh, T.1    Rohit, M.2    Grover, A.3    Malhotra, S.4    Vijayvergiya, R.A.5
  • 61
    • 33746206340 scopus 로고    scopus 로고
    • Bosentan therapy in patients with Eisenmenger syndrome: A multicenter, double-blind, randomized, placebo-controlled study
    • DOI 10.1161/CIRCULATIONAHA.106.630715, PII 0000301720060704000012
    • Galie N, Beghetti M, Gatzoulis MA, Granton J, Berger RM, Lauer A et al. for the Bosentan Randomized Trial of Endothelin Antagonist Therapy. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 2006; 114:48-54. (Pubitemid 44305274)
    • (2006) Circulation , vol.114 , Issue.1 , pp. 48-54
    • Galie, N.1    Beghetti, M.2    Gatzoulis, M.A.3    Granton, J.4    Berger, R.M.F.5    Lauer, A.6    Chiossi, E.7    Landzberg, M.8
  • 62
    • 46449124591 scopus 로고    scopus 로고
    • Ambrisentan for the treatment of pulmonary arterial hyperten- Sion
    • for the Ambrisentan in Pulmonary Arterial Hypertension RDBP-CMESAG. Results of the Ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, Efficacy (ARIES) Study 1 and 2
    • Galie N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA et al. for the Ambrisentan in Pulmonary Arterial Hypertension RDBP-CMESAG. Ambrisentan for the treatment of pulmonary arterial hyperten- sion. Results of the Ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, Efficacy (ARIES) Study 1 and 2. Circulation 2008; 117:3010-9.
    • (2008) Circulation , vol.117 , pp. 3010-3019
    • Galie, N.1    Olschewski, H.2    Oudiz, R.J.3    Torres, F.4    Frost, A.5    Ghofrani, H.A.6
  • 63
    • 67649523052 scopus 로고    scopus 로고
    • On behalf of the Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group- Tadalafil Therapy for Pulmonary Arterial Hypertension
    • Galie N, Brundage BH, Ghofranie HA, et al on behalf of the Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group- Tadalafil Therapy for Pulmonary Arterial Hypertension. Circulation 2009; 119:2894-903.
    • (2009) Circulation , vol.119 , pp. 2894-2903
    • Galie, N.1    Brundage, B.H.2    Ghofranie, H.A.3
  • 64
    • 80051559475 scopus 로고    scopus 로고
    • Vardenafil in pulmonary arterial hypertension: A randomized, double-blind, placebo-controlled study
    • for the Efficacy and Safety of Vardenafil in the Treatment of Pulmonary Arterial Hypertension (EVALUATION) Study Group
    • Jing ZC, Yu ZX, Shen JY, Wu BX, Xu KF, Zhu XY et al. for the Efficacy and Safety of Vardenafil in the Treatment of Pulmonary Arterial Hypertension (EVALUATION) Study Group. Vardenafil in pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled study. Am J Respir Crit Care Med 2001,183:1723-9.
    • (2001) Am J Respir Crit Care Med , vol.183 , pp. 1723-1729
    • Jing, Z.C.1    Yu, Z.X.2    Shen, J.Y.3    Wu, B.X.4    Xu, K.F.5    Zhu, X.Y.6
  • 65
    • 77954758530 scopus 로고    scopus 로고
    • Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
    • Humbert M, Sitbon O, Chaouat A, Bertocchi M, Habib G, Gressin V et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 2010;122:156-63.
    • (2010) Circulation , vol.122 , pp. 156-163
    • Humbert, M.1    Sitbon, O.2    Chaouat, A.3    Bertocchi, M.4    Habib, G.5    Gressin, V.6
  • 66
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo GE, Barst RJ, Ayres SM, Bergofsky EH, Brundage BH, Detre KM, et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 1991;115:343-9.
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3    Bergofsky, E.H.4    Brundage, B.H.5    Detre, K.M.6
  • 69
    • 54549125950 scopus 로고    scopus 로고
    • Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
    • Simonneau G, Rubin LJ, Galiè N, Barst RJ, Fleming TR, Frost AE et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 2008;149:521-30.
    • (2008) Ann Intern Med , vol.149 , pp. 521-530
    • Simonneau, G.1    Rubin, L.J.2    Galiè, N.3    Barst, R.J.4    Fleming, T.R.5    Frost, A.E.6
  • 70
    • 77952301237 scopus 로고    scopus 로고
    • Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: A randomized controlled clinical trial
    • McLaughlin VV, Benza RL, Rubin LI, Channick RN, Voswinckel R, Tapson VF et al. Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. J Am Coll Cardiol 2010;55:1915-22.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1915-1922
    • McLaughlin, V.V.1    Benza, R.L.2    Rubin, L.I.3    Channick, R.N.4    Voswinckel, R.5    Tapson, V.F.6
  • 72
    • 79955845135 scopus 로고    scopus 로고
    • Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension
    • for the Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group
    • Barst RJ, Oudiz RJ, Beardsworth A, Brundage BH, Simonneau G, Ghofrani HA et al. for the Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group. Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension. J Heart Lung Transplant 2011;30:632-43.
    • (2011) J Heart Lung Transplant , vol.30 , pp. 632-643
    • Barst, R.J.1    Oudiz, R.J.2    Beardsworth, A.3    Brundage, B.H.4    Simonneau, G.5    Ghofrani, H.A.6
  • 73
    • 79953009253 scopus 로고    scopus 로고
    • The bosentan patient registry: Long-term survival in pulmonary arterial hypertension
    • Keogh A, Strange G, McNeil K, Williams TJ, Gabbay E, Proudman S et al. The bosentan patient registry: long-term survival in pulmonary arterial hypertension. Intern Med J 2011;41:227-34.
    • (2011) Intern Med J , vol.41 , pp. 227-234
    • Keogh, A.1    Strange, G.2    McNeil, K.3    Williams, T.J.4    Gabbay, E.5    Proudman, S.6
  • 74
    • 82555194840 scopus 로고    scopus 로고
    • Upfront Triple combination therapy of I.V. epoprostenol with oral bosentan and sildenafil in idiopathic and heritable pulmonary arterial hypertension
    • Sitbon O, Jais S, Savale L. Upfront Triple combination therapy of I.V. epoprostenol with oral bosentan and sildenafil in idiopathic and heritable pulmonary arterial hypertension. Am J Respir Crit Care Med2011;183:A5910.
    • (2011) Am J Respir Crit Care Med , vol.183
    • Sitbon, O.1    Jais, S.2    Savale, L.3
  • 75
    • 0034817271 scopus 로고    scopus 로고
    • Atrial septostomy for pulmonary hypertension
    • DOI 10.1016/S0272-5231(05)70291-4
    • Sandoval J, Rothman A, Pulido T. Atrial septostomy for pulmonary hypertension. Clin Chest Med 2001;22:547-60. (Pubitemid 32912086)
    • (2001) Clinics in Chest Medicine , vol.22 , Issue.3 , pp. 547-560
    • Sandoval, J.1    Rothman, A.2    Pulido, T.3
  • 79
    • 84856393276 scopus 로고    scopus 로고
    • Relationship between reactive pulmonary hypertension and mortality in patients with acute decompensated heart failure
    • Aronson D, Eitan A, Dragu R, Burger AJ. Relationship between reactive pulmonary hypertension and mortality in patients with acute decompensated heart failure. Circ Heart Fail 2011;4:644-50.
    • (2011) Circ Heart Fail , vol.4 , pp. 644-650
    • Aronson, D.1    Eitan, A.2    Dragu, R.3    Burger, A.J.4
  • 80
    • 0034601744 scopus 로고    scopus 로고
    • Secondary pulmonary hypertension in chronic heart failure: The role of the endothelium in pathophysiology and management
    • Mores DL, Colucci WS, Givertz MM. Secondary pulmonary hypertension in chronic heart failure: the role of the endothelium in pathophysiology and management. Circulation 2000;102:1718-23.
    • (2000) Circulation , vol.102 , pp. 1718-1723
    • Mores, D.L.1    Colucci, W.S.2    Givertz, M.M.3
  • 83
    • 74949120067 scopus 로고    scopus 로고
    • Effects of right ventricular ejection fraction on outcomes in chronic systolic heart failure
    • Meyer P, Filippatos GS, Ahmed MI, Iskandrian AE, Bittner V, Perry GJ, et al. Effects of right ventricular ejection fraction on outcomes in chronic systolic heart failure. Circulation 2010;121:252-8.
    • (2010) Circulation , vol.121 , pp. 252-258
    • Meyer, P.1    Filippatos, G.S.2    Ahmed, M.I.3    Iskandrian, A.E.4    Bittner, V.5    Perry, G.J.6
  • 85
    • 0036774973 scopus 로고    scopus 로고
    • Do results of the ENABLE (Endothelin Antagonist Bosentan for Lowering Cardiac Events in Heart Failure) study spell the end for non-selective endothelin antagonism in heart failure?
    • DOI 10.1016/S0167-5273(02)00182-1, PII S0167527302001821
    • Kalra PR, Moon JC, Coats AJ. Do results of the ENABLE (Endothelin Antagonist Bosentan for Lowering Cardiac Events in Heart Failure) study spell the end for non-selective endothelin antagonism in heart failure? Int J Cardiol 2002;85:195-7. (Pubitemid 35245980)
    • (2002) International Journal of Cardiology , vol.85 , Issue.2-3 , pp. 195-197
    • Kalra, P.R.1    Moon, J.C.C.2    Coats, A.J.S.3
  • 86
    • 3242810591 scopus 로고    scopus 로고
    • A Receptor Antagonist Trial in Heart Failure (EARTH): Randomised, double-blind, placebo-controlled trial
    • DOI 10.1016/S0140-6736(04)16723-8, PII S0140673604167238
    • Anand I, McMurray J, Cohn JN, Konstam MA, NotterT, Quitzau K et al. Long-term effects of darusentan on left-ventricular remodelling and clinical outcomes in the EndothelinA Receptor Antagonist Trial in Heart Failure (EARTH): randomised, double-blind, placebo-controlled trial. Lancet 2004;364:347-54. (Pubitemid 38970011)
    • (2004) Lancet , vol.364 , Issue.9431 , pp. 347-354
    • Anand, P.I.1    McMurray, P.J.2    Cohn, P.J.N.3    Konstam, P.M.A.4    Notter, T.5    Quitzau, K.6    Ruschitzka, F.7    Luscher, P.T.F.8
  • 87
    • 40149087049 scopus 로고    scopus 로고
    • Clinical and hemodynamic effects of bosentan dose optimization in symptomatic heart failure patients with severe systolic dysfunction, associated with secondary pulmonary hypertension - A multi-center randomized study
    • DOI 10.1159/000107791
    • Kaluski E, Cotter G, Leitman M, Milo-Cotter O, Krakover R, Kobrin I et al. Clinical and hemodynamic effects of bosentan dose optimization in symptomatic heart failure patients with severe systolic dysfunction, associated with secondary pulmonary hypertension-a multi-center randomized study. Cardiology 2008;109:273-80. (Pubitemid 351328923)
    • (2008) Cardiology , vol.109 , Issue.4 , pp. 273-280
    • Kaluski, E.1    Cotter, G.2    Leitman, M.3    Milo-Cotter, O.4    Krakover, R.5    Kobrin, I.6    Moriconi, T.7    Rainisio, M.8    Caspi, A.9    Reizin, L.10    Zimlichman, R.11    Vered, Z.12
  • 90
    • 79960396933 scopus 로고    scopus 로고
    • Pulmonary hypertension in heart failure with preserved ejection fraction: A target of phosphodiesterase-5 inhibition in a 1-year study
    • Guazzi M, Vicenzi M, Arena R, Guazzi MD. Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study. Circulation 2011;124:164-74.
    • (2011) Circulation , vol.124 , pp. 164-174
    • Guazzi, M.1    Vicenzi, M.2    Arena, R.3    Guazzi, M.D.4
  • 91
    • 19844369633 scopus 로고    scopus 로고
    • Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation
    • DOI 10.1378/chest.127.5.1531
    • Thabut G, Dauriat G, Stern JB, Logeart D, Levy A, Marrash-Chahla R et al. Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation. Chest 2005;127:1531-6. (Pubitemid 46218776)
    • (2005) Chest , vol.127 , Issue.5 , pp. 1531-1536
    • Thabut, G.1    Dauriat, G.2    Stern, J.B.3    Logeart, D.4    Levy, A.5    Marrash-Chahla, R.6    Mal, H.7
  • 92
    • 38449102031 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with pulmonary fibrosis awaiting lung transplant
    • DOI 10.1183/09031936.00107206
    • Shorr AF, Wainright JL, Cors CS, Lettieri CJ, Nathan SD. Pulmonary hypertension in patients with pulmonary fibrosis awaiting lung transplant. Eur Respir J 2007;30:715-21. (Pubitemid 351194832)
    • (2007) European Respiratory Journal , vol.30 , Issue.4 , pp. 715-721
    • Shorr, A.F.1    Wainright, J.L.2    Cors, C.S.3    Lettieri, C.J.4    Nathan, S.D.5
  • 93
    • 70349673627 scopus 로고    scopus 로고
    • Pulmonary vascular resistance predicts early mortality in patients with diffuse fibrotic lung disease and suspected pulmonary hypertension
    • Corte TJ, Wort SJ, Gatzoulis MA, Macdonald P, Hansell DM, Wells AU. Pulmonary vascular resistance predicts early mortality in patients with diffuse fibrotic lung disease and suspected pulmonary hypertension. Thorax 2009;64:883-8.
    • (2009) Thorax , vol.64 , pp. 883-888
    • Corte, T.J.1    Wort, S.J.2    Gatzoulis, M.A.3    Macdonald, P.4    Hansell, D.M.5    Wells, A.U.6
  • 96
    • 0018885920 scopus 로고
    • Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: A clinical trial
    • Nocturnal Oxygen Therapy Trial Group
    • Nocturnal Oxygen Therapy Trial Group. Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Ann Intern Med 1980;93:391-8.
    • (1980) Ann Intern Med , vol.93 , pp. 391-398
  • 97
    • 79955383388 scopus 로고    scopus 로고
    • Nocturnal desaturation is associated with pulmonary hypertension in patients with mild to moderate interstitial lung disease
    • Corte T, Talbot S, Wort S, Wells A. Nocturnal desaturation is associated with pulmonary hypertension in patients with mild to moderate interstitial lung disease. Am J Respir Crit Care Med 2009;179:A4057
    • (2009) Am J Respir Crit Care Med , vol.179
    • Corte, T.1    Talbot, S.2    Wort, S.3    Wells, A.4
  • 99
    • 70349634397 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension
    • Task Force for Diagnosis and Treatment of Pulmonary Hypertension of European Society of Cardiology (ESC); European Respiratory Society (ERS); International Society of Heart and Lung Transplantation (ISHLT)
    • Task Force for Diagnosis and Treatment of Pulmonary Hypertension of European Society of Cardiology (ESC); European Respiratory Society (ERS); International Society of Heart and Lung Transplantation (ISHLT), Galiè N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA et al. Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2009;34:1219-63.
    • (2009) Eur Respir J , vol.34 , pp. 1219-1263
    • Galiè, N.1    Hoeper, M.M.2    Humbert, M.3    Torbicki, A.4    Vachiery, J.L.5    Barbera, J.A.6
  • 100
    • 57449105233 scopus 로고    scopus 로고
    • Diagnosis and treatment of secondary (noncategory 1) pulmonary hypertension
    • Rich S, Rabinovitch M. Diagnosis and treatment of secondary (noncategory 1) pulmonary hypertension. Circulation 2008; 118:2190-9.
    • (2008) Circulation , vol.118 , pp. 2190-2199
    • Rich, S.1    Rabinovitch, M.2
  • 104
    • 83455185083 scopus 로고    scopus 로고
    • Presence of right ventricular dysfunction modifies treatment response to sildenafil in the stepipftrial
    • Han MK, Bach D, Hagan P. Presence Of Right Ventricular Dysfunction Modifies Treatment Response To Sildenafil In The StepIPFTrial. Am J Respir Crit Care Med 2011;183:A5301.
    • (2011) Am J Respir Crit Care Med , vol.183
    • Han, M.K.1    Bach, D.2    Hagan, P.3
  • 106
    • 77649229083 scopus 로고    scopus 로고
    • Riociguat: An upcoming therapy in chronic thromboembolic pulmonary hypertension?
    • Kim NH. Riociguat: an upcoming therapy in chronic thromboembolic pulmonary hypertension? Eur Respir Rev 2010;19:68-71.
    • (2010) Eur Respir Rev , vol.19 , pp. 68-71
    • Kim, N.H.1
  • 107
    • 61649096898 scopus 로고    scopus 로고
    • Managing chronic thromboembolic pulmonary hypertension: Pharmacological treatment options
    • Lang IM. Managing chronic thromboembolic pulmonary hypertension: pharmacological treatment options. Eur Respir Rev 2009;18:24-8.
    • (2009) Eur Respir Rev , vol.18 , pp. 24-28
    • Lang, I.M.1
  • 108
    • 49449102583 scopus 로고    scopus 로고
    • Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension
    • Suntharalingam J, Treacy CM, Doughty NJ, Goldsmith K, Soon E, Toshner MR et al. Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension. Chest 2008;134:229-36.
    • (2008) Chest , vol.134 , pp. 229-236
    • Suntharalingam, J.1    Treacy, C.M.2    Doughty, N.J.3    Goldsmith, K.4    Soon, E.5    Toshner, M.R.6
  • 109
    • 57449103127 scopus 로고    scopus 로고
    • Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronic Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial
    • Jais X, D'Armini AM, Jansa P, Torbicki A, Delcroix M, Ghofrani HA et al. Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronic Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial. J Am Coll Cardiol 2008;52:2127-34.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 2127-2134
    • Jais, X.1    D'Armini, A.M.2    Jansa, P.3    Torbicki, A.4    Delcroix, M.5    Ghofrani, H.A.6
  • 112
    • 84858809665 scopus 로고    scopus 로고
    • Imatinib Improves Exercise Capacity and Hemodynamics at 24 Weeks as Add-on Therapy in Symptomatic Pulmonary Arterial Hypertension Patients
    • The IM-PRES Study
    • Hoeper M, Barst R, Bourge R et al. Imatinib Improves Exercise Capacity and Hemodynamics at 24 Weeks as Add-on Therapy in Symptomatic Pulmonary Arterial Hypertension Patients: The IM-PRES Study. Chest 2011;140:A1045.
    • (2011) Chest , vol.140
    • Hoeper, M.1    Barst, R.2    Bourge, R.3
  • 113
    • 61649094752 scopus 로고    scopus 로고
    • Soluble guanylate cyclase stimulation: An emerging option in pulmonary hypertension therapy
    • Ghofrani HA, Grimminger F. Soluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy. Eur Respir Rev 2009;18:35-41.
    • (2009) Eur Respir Rev , vol.18 , pp. 35-41
    • Ghofrani, H.A.1    Grimminger, F.2
  • 114
    • 77956664858 scopus 로고    scopus 로고
    • Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: A phase II study
    • Ghofrani HA, Hoeper MM, Halank M, Meyer FJ, Staehler G, Behr J et al. Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study. Eur Respir J 2010;36:792-9.
    • (2010) Eur Respir J , vol.36 , pp. 792-799
    • Ghofrani, H.A.1    Hoeper, M.M.2    Halank, M.3    Meyer, F.J.4    Staehler, G.5    Behr, J.6
  • 115
    • 54949091985 scopus 로고    scopus 로고
    • Cicletanine for the treatment of pulmonary arterial hypertension
    • Waxman AB, Lawler L, Cornett G. Cicletanine for the treatment of pulmonary arterial hypertension. Arch Intern Med 2008; 168:2164-6.
    • (2008) Arch Intern Med , vol.168 , pp. 2164-2166
    • Waxman, A.B.1    Lawler, L.2    Cornett, G.3
  • 116
    • 84858819744 scopus 로고    scopus 로고
    • Cicletanine therapy is well tolerated in patients with advanced pulmonary arterial hypertension
    • Waxman AB, Lawler L. Cicletanine therapy is well tolerated in patients with advanced pulmonary arterial hypertension. Am J of Resp Critic Care Med 2009;179:A3353.
    • (2009) Am J of Resp Critic Care Med , vol.179
    • Waxman, A.B.1    Lawler, L.2
  • 117
    • 77957237185 scopus 로고    scopus 로고
    • Selexipag: A selective prostacyclin receptor agonist that does not affect rat gastric function
    • Morrison K, Ernst R, Hess P, Studer R, Clozel M. Selexipag: a selective prostacyclin receptor agonist that does not affect rat gastric function. J Pharmacol Exp Ther 2010;335:249-55.
    • (2010) J Pharmacol Exp Ther , vol.335 , pp. 249-255
    • Morrison, K.1    Ernst, R.2    Hess, P.3    Studer, R.4    Clozel, M.5
  • 118
    • 79551663361 scopus 로고    scopus 로고
    • Efficacy, safety and tolerability of act-293987, a novel oral, non-prostanoid, prostaglandin 12 (ip) receptor agonist: Results from a phase iia study in pulmonary arterial hypertension
    • Simonneau G, Lang I, Torbicki A. Efficacy, Safety And Tolerability Of ACT-293987, A Novel Oral, Non-prostanoid, Prostaglandin 12 (IP) Receptor Agonist: Results From A Phase IIa Study In Pulmonary Arterial Hypertension. Am J Respir Crit Care Med 2010;181:A2515.
    • (2010) Am J Respir Crit Care Med , vol.181
    • Simonneau, G.1    Lang, I.2    Torbicki, A.3
  • 120
    • 78649264743 scopus 로고    scopus 로고
    • Effects of inhaled Aviptadil (vasoactive intestinal peptide) in patients with pulmonary arterial hypertension
    • Galie N, Boonstra A, Ewert R. Effects of inhaled Aviptadil (vasoactive intestinal peptide) in patients with pulmonary arterial hypertension. Am J of Resp Critic Care Med 2010;181:A2516.
    • (2010) Am J of Resp Critic Care Med , vol.181
    • Galie, N.1    Boonstra, A.2    Ewert, R.3
  • 122
    • 77957832881 scopus 로고    scopus 로고
    • Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: Comparison with bosentan and sildenafil
    • Mouchers KT, Schalij I, de Boer MA, Postmus PE, van Hinsbergh VW et al. Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil. Eur Respir J 2010;36:800-7.
    • (2010) Eur Respir J , vol.36 , pp. 800-807
    • Mouchers, K.T.1    Schalij, I.2    De Boer, M.A.3    Postmus, P.E.4    Van Hinsbergh, V.W.5
  • 123
    • 14244260105 scopus 로고    scopus 로고
    • Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
    • DOI 10.1136/hrt.2003.029470
    • Fukumoto Y, Matoba T, Ito A, Tanaka H, Kishi T, Hayashidani S et al. Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart 2005;91:391-2. (Pubitemid 40299237)
    • (2005) Heart , vol.91 , Issue.3 , pp. 391-392
    • Fukumoto, Y.1    Matoba, T.2    Ito, A.3    Tanaka, H.4    Kishi, T.5    Hayashidani, S.6    Abe, K.7    Takeshita, A.8    Shimokawa, H.9
  • 125
    • 0028788150 scopus 로고
    • Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: Relation to hemodynamic variables and endothelin levels
    • Nootens M, Kaufmann E, Rector T, Toher C, Judd D, Francis GS et al. Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels. J Am Coll Cardiol 1995;26:1581-5.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1581-1585
    • Nootens, M.1    Kaufmann, E.2    Rector, T.3    Toher, C.4    Judd, D.5    Francis, G.S.6
  • 126
    • 77649228421 scopus 로고    scopus 로고
    • Perspectives on novel therapeutic strategies for right heart failure in pulmonary arterial hypertension: Lessons from the left heart
    • Handoko ML, de Man FS, AIlaart CP, Paulus WJ, Westerhof N, Vonk-Noordegraaf A. Perspectives on novel therapeutic strategies for right heart failure in pulmonary arterial hypertension: lessons from the left heart. Eur Respir Rev 2010;19:72-82.
    • (2010) Eur Respir Rev , vol.19 , pp. 72-82
    • Handoko, M.L.1    De Man, F.S.2    Ailaart, C.P.3    Paulus, W.J.4    Westerhof, N.5    Vonk-Noordegraaf, A.6
  • 127
    • 70350509631 scopus 로고    scopus 로고
    • Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats
    • Okada M, Harada T, Kikuzuki R, Yamawaki H, Hara Y. Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats. J Pharmacol Sci 2009;111:193-200.
    • (2009) J Pharmacol Sci , vol.111 , pp. 193-200
    • Okada, M.1    Harada, T.2    Kikuzuki, R.3    Yamawaki, H.4    Hara, Y.5
  • 128
    • 0035928756 scopus 로고    scopus 로고
    • Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: Importance of kinins and influence on angiotensin II type 1 receptor signaling pathway
    • Rouleau JL, Kapuku G, Pelletier S, Gosselin H, Adam A, Gagnon C et al. Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway. Circulation 2001;104:939-44. (Pubitemid 32778047)
    • (2001) Circulation , vol.104 , Issue.8 , pp. 939-944
    • Rouleau, J.L.1    Kapuku, G.2    Pelletier, S.3    Gosselin, H.4    Adam, A.5    Gagnon, C.6    Lambert, C.7    Meloche, S.8
  • 129
    • 77957694135 scopus 로고    scopus 로고
    • Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats
    • Bogaard HJ, Natarajan R, Mizuno S, Abbate A, Chang PJ, Chau VQ et al. Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats. Am J Respir Crit Care Med 2010;182:652-60.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 652-660
    • Bogaard, H.J.1    Natarajan, R.2    Mizuno, S.3    Abbate, A.4    Chang, P.J.5    Chau, V.Q.6
  • 130
    • 78049344580 scopus 로고    scopus 로고
    • Chronic treatment with low-dose bisoprolol improves survival and cardiac function in experimental pulmonary arterial hypertension
    • Handoko ML, de Man F, van Ballegoij J. Chronic treatment with low-dose bisoprolol improves survival and cardiac function in experimental pulmonary arterial hypertension. Am J Resp Critic Care Med 2010;181:A4896.
    • (2010) Am J Resp Critic Care Med , vol.181
    • Handoko, M.L.1    De Man, F.2    Van Ballegoij, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.