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1
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0025336568
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Breakthrough pain: Definition, prevalence and characteristics
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The first attempt to provide a definition for breakthrough cancer pain
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Portenoy RK, Hagen NA. Breakthrough pain: Definition, prevalence and characteristics. Pain 1990;41:273-81. The first attempt to provide a definition for breakthrough cancer pain
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(1990)
Pain
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Portenoy, R.K.1
Hagen, N.A.2
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2
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0032899247
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Breakthrough pain: Characteristics and impact in patients with cancer pain
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Portenoy RK, Payne D, Jacobson P. Breakthrough pain: Characteristics and impact in patients with cancer pain. Pain 1999;81:129-34
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Pain
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Portenoy, R.K.1
Payne, D.2
Jacobson, P.3
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3
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80051663933
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The use of rapid onset opioids for breakthrough cancer pain: The challenge of its dosing
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Mercadante S. The use of rapid onset opioids for breakthrough cancer pain: The challenge of its dosing. Crit Rev Oncol Hematol 2011;80:460-5
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Crit Rev Oncol Hematol
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Mercadante, S.1
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4
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43049104583
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Opioids for cancer breakthrough pain: A pilot study reporting patient assessment of time to meaningful pain relief
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Zeppetella GB. Opioids for cancer breakthrough pain: A pilot study reporting patient assessment of time to meaningful pain relief. J Pain Symptom Manage 2008;35:563-7
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(2008)
J Pain Symptom Manage
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Zeppetella, G.B.1
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7
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0025985939
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Absorption and availability of moral trasmucosal fentanyl citrate
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Streisand J, Varvel J, Stanski DR, et al. Absorption and availability of moral trasmucosal fentanyl citrate. Anesthesiology 1991;75:223-9
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(1991)
Anesthesiology
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Streisand, J.1
Varvel, J.2
Stanski, D.R.3
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8
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28444445630
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Evidence-based pral transmucosal fentanyl citrate (OTFC) dosing guidelines
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Aronoff G, Brennan M, Pritchard D, Ginsberg B. Evidence-based pral transmucosal fentanyl citrate (OTFC) dosing guidelines. Pain Med 2005;6:305-14
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Pain Med
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Aronoff, G.1
Brennan, M.2
Pritchard, D.3
Ginsberg, B.4
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9
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0031892618
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Dose proportionality and pharmacokinetics of oral transmucosal fentanyl citrate
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A pharmacokinetic study providing relevant data about OTF.C.
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Streisand JB, Busch MA, Egan TD, et al. Dose proportionality and pharmacokinetics of oral transmucosal fentanyl citrate. Anesthesiology 1998;88:305-9. A pharmacokinetic study providing relevant data about OTF.C.
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Anesthesiology
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Streisand, J.B.1
Busch, M.A.2
Egan, T.D.3
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10
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0042121265
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A pharmacokinetic study to compare two simultaneous 400 microg doses with a single 800 microg dose of oral transmucosal fentanyl citrate
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Lee M, Kern S, Kisicki J, Egan T. A pharmacokinetic study to compare two simultaneous 400 microg doses with a single 800 microg dose of oral transmucosal fentanyl citrate. J Pain Symptom Manage 2003;26:743-7
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J Pain Symptom Manage
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Lee, M.1
Kern, S.2
Kisicki, J.3
Egan, T.4
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11
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0034050328
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Multiple dose pharmacokinetics of oral transmucosal fentanyl citrate in healthy volunteers
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A pharmacokinetic study providing relevant data about OTF.C.
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Egan T, Sharma A, Ashburn M, et al. Multiple dose pharmacokinetics of oral transmucosal fentanyl citrate in healthy volunteers. Anesthesiology 2000;92:665-73. A pharmacokinetic study providing relevant data about OTF.C.
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(2000)
Anesthesiology
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, pp. 665-673
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Egan, T.1
Sharma, A.2
Ashburn, M.3
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12
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4344680011
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Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucisal fenatnyl citrate
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Kharasch E, Whittington D, Hoffer C. Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucisal fenatnyl citrate. Anesthesiology 2004;101:729-37
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Anesthesiology
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Kharasch, E.1
Whittington, D.2
Hoffer, C.3
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13
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2442712489
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Tolerability and effects of two formulations of oral trasmucosal fentanyl citrate (OTFC;ACTIQ) in patients with radiation-induced oral mucositis
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Shaiova L, Lapin J, Manco L, et al. Tolerability and effects of two formulations of oral trasmucosal fentanyl citrate (OTFC;ACTIQ) in patients with radiation-induced oral mucositis. Support Care Cancer 2004;12:268-73
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Support Care Cancer
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Shaiova, L.1
Lapin, J.2
Manco, L.3
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14
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29244485895
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Oral trasnsmucosal fentanyl citrate and xerostomia
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Davies A, Vriens J. Oral trasnsmucosal fentanyl citrate and xerostomia. J Pain Symptom Manage 2005;30:496-7
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(2005)
J Pain Symptom Manage
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Davies, A.1
Vriens, J.2
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15
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0032522607
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Oral transmucosal fentanyl citrate: A randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients
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The first placebo-controlled study of OTF.C.
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Farrar J, Cleary J, Rauck R, et al. Oral transmucosal fentanyl citrate: A randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients. J Natl Cancer Inst 1998;90:611-16. The first placebo-controlled study of OTF.C.
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(1998)
J Natl Cancer Inst
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, pp. 611-616
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Farrar, J.1
Cleary, J.2
Rauck, R.3
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16
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0032981296
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Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: A controlled dose titration study
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Portenoy RK, Payne R, Coluzzi P, et al. Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: A controlled dose titration study. Pain 1999;79:303-12
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(1999)
Pain
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Portenoy, R.K.1
Payne, R.2
Coluzzi, P.3
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17
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0031759360
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Dose-titration multicenter study of transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain
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Christie J, Simmonds M, Patt R, et al. Dose-titration multicenter study of transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain. J Clin Oncol 1998;16:3238-45
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J Clin Oncol
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Christie, J.1
Simmonds, M.2
Patt, R.3
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18
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0035059131
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Breakthrough cancer pain: A randomized trial comparing oral transmucosal fentanyl citrate (OTFC) and morphine sulphate immediate release (MSIR)
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The first study comparing OTFC with oral morphine
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Coluzzi P, Schwartzberg L, Conroy J, et al. Breakthrough cancer pain: A randomized trial comparing oral transmucosal fentanyl citrate (OTFC) and morphine sulphate immediate release (MSIR). Pain 2001;91:123-30. The first study comparing OTFC with oral morphine
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(2001)
Pain
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, pp. 123-130
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Coluzzi, P.1
Schwartzberg, L.2
Conroy, J.3
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19
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34250339548
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Transmucosal fentanyl vs intravenous morphine in doses proportional to basal opioid regimen for episodic-breakthrough pain
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The first study comparing OTFC with an active substance, also showing that proportional doses are effective and safe
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Mercadante S, Villari P, Ferrera P, et al. Transmucosal fentanyl vs intravenous morphine in doses proportional to basal opioid regimen for episodic-breakthrough pain. Br J Cancer 2007;96:1828-33. The first study comparing OTFC with an active substance, also showing that proportional doses are effective and safe
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(2007)
Br J Cancer
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, pp. 1828-1833
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Mercadante, S.1
Villari, P.2
Ferrera, P.3
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20
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72549097280
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A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: An open-label, randomized, crossover trial
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Another study comparing OTFC with a more recent delivery systems
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Mercadante S, Radbruck L, Davies A, et al. A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: An open-label, randomized, crossover trial. Curr Med Res Opin 2009;25:2805-15. Another study comparing OTFC with a more recent delivery systems
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(2009)
Curr Med Res Opin
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, pp. 2805-2815
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Mercadante, S.1
Radbruck, L.2
Davies, A.3
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21
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61849093095
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Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. The management of cancer-related breakthrough pain: Recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland
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Davies AN, Dickman A, Reid C, et al. Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. The management of cancer-related breakthrough pain: Recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. Eur J Pain 2009;13:331-8
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Eur J Pain
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Davies, A.N.1
Dickman, A.2
Reid, C.3
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22
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33846916463
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A titration strategy is needed to manage breakthrough cancer pain effectively: Observations from data pooled from three clinical trials
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Hagen NA, Fisher K, Victorino C, Farrar JT. A titration strategy is needed to manage breakthrough cancer pain effectively: Observations from data pooled from three clinical trials. J Palliat Med 2007;10:47-55
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J Palliat Med
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Hagen, N.A.1
Fisher, K.2
Victorino, C.3
Farrar, J.T.4
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23
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10644251822
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Oral transmucosal fentanyl citrate in the management of breakthrough pain in cancer; an open, multicentre, dose-titration and long-term use study
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Hanks GW, Nugent M, Higgs C, Busch M. Oral transmucosal fentanyl citrate in the management of breakthrough pain in cancer; an open, multicentre, dose-titration and long-term use study. Palliat Med 2004;18:698-704
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Palliat Med
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Hanks, G.W.1
Nugent, M.2
Higgs, C.3
Busch, M.4
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24
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2142698683
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Oral transmucosal citrate in the outpatient management of severe cancer pain crisis: A retrospective case series
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Burton AW, Driver L, Mendoza T, Syed G. Oral transmucosal citrate in the outpatient management of severe cancer pain crisis: A retrospective case series. Clin J Pain 2004;20:195-7
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Clin J Pain
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Burton, A.W.1
Driver, L.2
Mendoza, T.3
Syed, G.4
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25
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0034965392
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Long-term safety of oral transmucosal fentanyl citrate for breakthrough cancer pain
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Payne R, Coluzzi P, Hart L, et al. Long-term safety of oral transmucosal fentanyl citrate for breakthrough cancer pain. J Pain Symptom Manage 2001;22:575-83
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(2001)
J Pain Symptom Manage
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Payne, R.1
Coluzzi, P.2
Hart, L.3
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26
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79955627820
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Rampant caries from oral transmucosal fentanyl citrate lozenge abuse
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Mandel L, Carunchio MJ. Rampant caries from oral transmucosal fentanyl citrate lozenge abuse. J Am Dent Assoc 2011;142:405-9
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J Am Dent Assoc
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Mandel, L.1
Carunchio, M.J.2
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27
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33846114165
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Fentanyl buccal tablet in breakthrough pain in opioid-tolerant patients with cancer: A viewpoint by Sebastiano Mercadante
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Mercadante S. Fentanyl buccal tablet in breakthrough pain in opioid-tolerant patients with cancer: A viewpoint by Sebastiano Mercadante. Drugs 2006;66:2394-5
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Drugs
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Mercadante, S.1
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