Cannabis findings in drivers suspected of driving under the influence of drugs in Finland from 2006 to 2008

Forensic Science International

Volumn 217, Issue 1-3, 2012, Pages 107-112

  Blencowe, Tom ^a   Pehrsson, Anna ^a   Mykkänen, Sirpa ^a   Gunnar, Teemu ^a   Lillsunde, Pirjo ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Blood; Cannabis; DUID; Impairment; THC

Indexed keywords

11 HYDROXYDRONABINOL; ALCOHOL; AMPHETAMINE; BENZODIAZEPINE; CANNABIS; DRONABINOL; TETRAHYDROCANNABINOLIC ACID;

ACCURACY; ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BREATH ANALYSIS; CAR DRIVING; CONTROLLED STUDY; DRIVING UNDER THE INFLUENCE OF DRUG; DRUG USE; FEMALE; FINLAND; FORENSIC TOXICOLOGY; GENDER; GROUPS BY AGE; HUMAN; HUMAN EXPERIMENT; MALE; POLICE; PREVALENCE; PRIORITY JOURNAL;

EID: 84858798622     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2011.10.031     Document Type: Article

References (43)

1. Bates M.N., Blakely T.A. Role of cannabis in motor vehicle crashes. Epidemiol. Rev. 1999, 21:222-232.
2. Drummer O.H. The Forensic Pharmacology of Drugs of Abuse 2001, Arnold, London.
3. UNODC World Drug Report 2010 2010, United Nations Publication, Vienna.
4. Kelly E., Darke S., Ross J. A review of drug use and driving: epidemiology, impairment, risk factors and risk perceptions. Drug Alcohol Rev. 2004, 23:319-344.
5. Huestis M.A., Henningfield J.E., Cone E.J. Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana. J. Anal. Toxicol. 1992, 16:276-282.
6. Longo M.C., Hunter C.E., Lokan R.J., White J.M., White M.A. The prevalence of alcohol, cannabinoids, benzodiazepines and stimulants amongst injured drivers and their role in driver culpability: part II: the relationship between drug prevalence and drug concentration and driver culpability. Accid. Anal. Prev. 2000, 32:623-632.
7. Drummer O.H., Gerostamoulos J., Batziris H., Chu M., Caplehorn J., Robertson M.D., Swann P. The incidence of drugs in drivers killed in Australian road traffic crashes. Forensic Sci. Int. 2003, 134:154-162.
8. Giovanardi D., Castellana C.N., Pisa S., Poppi B., Pinetti D., Bertolini A., Ferrari A. Prevalence of abuse of alcohol and other drugs among injured drivers presenting to the emergency department of the University Hospital of Modena, Italy. Drug Alcohol Depend. 2005, 80:135-138.
9. Mura P., Kintz P., Ludes B., Gaulier J.M., Marquet P., Martin-Dupont S., Vincent F., Kaddour A., Goulle J.P., Nouveau J., Moulsma M., Tilhet-Coartet S., Pourrat O. Comparison of the prevalence of alcohol, cannabis and other drugs between 900 injured drivers and 900 control subjects: results of a French collaborative study. Forensic Sci. Int. 2003, 133:79-85.
10. Schwilke E.W., dos Santos M.I.S., Logan B.K. Changing patterns of drug and alcohol use in fatally injured drivers in Washington state. J. Forensic Sci. 2006, 51:1191-1198.
11. Christophersen A.S., Ceder G., Kristinsson J., Lillsunde P., Steentoft A. Drugged driving in the Nordic countries - a comparative study between five countries. Forensic Sci. Int. 1999, 106:173-190.
12. Ojaniemi K.K., Lintonen T.R., Impinen A.O., Lillsunde P.M., Ostamo A.I. Trends in driving under the influence of drugs: a register-based study on DUID suspects during 1977-2007. Accid. Anal. Prev. 2009, 41:191-196.
13. Asbridge M., Poulin C., Donato A. Motor vehicle collision risk and driving under the influence of cannabis: evidence from adolescents in Atlantic Canada. Accid. Anal. Prev. 2005, 37:1025-1034.
14. Moskowitz H. Marijuana driving. Accid. Anal. Prev. 1985, 17:323-346.
15. Robbe H.W.J., O'Hanlon J.F. Marijauna and Actual Driving Performance. DOT HS-808-078 1993, U.S. Department of Transportation, Washington, DC.
16. Smiley A. Marijuana: on-road and driving-simulator studies. The Health Effects of Cannabis 1999, 171-191. CAMH, Toronto. H. Kalant, W.A. Corrigall, W. Hall, R.G. Smart (Eds.).
17. Solowij N., Michie P.T., Fox A.M. Differential impairments of selective attention due to frequency and duration of cannabis use. Biol. Psychiatry 1995, 37:731-739.
18. Ramaekers J.G., Berghaus G., van Laar M., Drummer O.H. Dose related risk of motor vehicle crashes after cannabis use. Drug Alcohol Depend. 2004, 73:109-119.
19. Bedard M., Dubois S., Weaver B. The impact of cannabis on driving. Can. J. Public Health 2007, 98:6-11.
20. Drummer O.H., Gerostamoulos J., Batziris H., Chu M., Caplehorn J., Robertson M.D., Swann P. The involvement of drugs in drivers of motor vehicles killed in Australian road traffic crashes. Accid. Anal. Prev. 2004, 36:239-248.
21. Papafotiou K., Carter J.D., Stough C. The relationship between performance on the standardised field sobriety tests, driving performance and the level of delta 9-tetrahydrocannabinol (THC) in blood. Forensic Sci. Int. 2005, 155:172-178.
22. Grotenhermen F., Leson G., Berghaus G., Drummer O.H., Krueger H.-P., Longo M., Moskowitz H., Perrine B., Ramaekers J.G., Smiley A., Tunbridge R. Developing limits for driving under cannabis. Addiction 2007, 102:1910-1917.
23. Karschner E.L., Schwilke E.W., Lowe R.H., Darwin W.D., Herning R.I., Cadet J.L., Huestis M.A. Implications of plasma Δ9-tetrahydrocannabinol, 11-hydroxy-THC, and 11-nor-9-carboxy-THC concentrations in chronic cannabis smokers. J. Anal. Toxicol. 2009, 33:469-477.
24. Huestis M.A., Barnes A., Smith M.L. Estimating the time of last cannabis use from plasma Delta(9)-tetrahydrocannabinol and II-nor-9-carboxy-Delta(9)-tetrahydrocannabinol concentrations. Clin. Chem. 2005, 51:2289-2295.
25. Papafotiou K., Carter J.D., Stough C. An evaluation of the sensitivity of the Standardised Field Sobriety Tests (SFSTs) to detect impairment due to marijuana intoxication. Psychopharmacology 2005, 180:107-114.
26. Robbe H. Marijuana's impairing effects on driving are moderate when taken alone but severe when combined with alcohol. Hum. Psychopharm. Clin. 1998, 13:S70-S78.
27. Solowij N., Stephens R.S., Roffman R.A., Babor T., Kadden R., Miller M., Christiansen K., McRee B., Vendetti J. Cognitive functioning of long-term heavy cannabis users seeking treatment. J. Am. Med. Assoc. 2002, 287:1123-1131.
28. Bolla K.I., Brown K., Eldreth D., Tate K., Cadet J.L. Dose-related neurocognitive effects of marijuana use. Neurology 2002, 59:1337-1343.
29. 9-THC concentration in serum and oral fluid: limits of impairment. Drug Alcohol Depend. 2006, 85:114-122.
30. Jones A.W., Holmgren A., Kugelberg F.C. Driving under the influence of cannabis: a 10-year study of age and gender differences in the concentrations of tetrahydrocannabinol in blood. Addiction 2008, 103:452-461.
31. Robbe H.W.J., O'Hanlon J. Marijauna Alcohol and Actual Driving Performance. DOT HS-808-939 1999, U.S. Department of Transportation, Washington, DC.
32. Morland J. Driving under the influence of non-alcohol drugs. Forensic Sci. Rev. 2000, 12:80-105.
33. Rajala P., Ariniemi K., Mykkanen S., Lillsunde P. Screening for abused drugs in blood samples using modified EMIT immunoassay. 6th Conference of the International Society of Addiction Medicine 2004.
34. Gunnar T., Mykkanen S., Ariniemi K., Lillsunde P. Validated semiquantitative/quantitative screening of 51 drugs in whole blood as silylated derivatives by gas chromatography-selected ion monitoring mass spectrometry and gas chromatography electron capture detection. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2004, 806:205-219.
35. Pehrsson A., Gunnar T., Engblom C., Seppa H., Jama A., Lillsunde P. Roadside oral fluid testing: comparison of the results of Drugwipe 5 and Drugwipe benzodiazepines on-site tests with laboratory confirmation results of oral fluid and whole blood. Forensic Sci. Int. 2008, 175:140-148.
36. Gunnar T., Ariniemi K., Lillsunde P. Fast gas chromatography-negative-ion chemical ionization mass spectrometry with microscale volume sample preparation for the determination of benzodiazepines and alpha-hydroxy metabolites, zaleplon and zopiclone in whole blood. J. Mass Spectrom. 2006, 41:741-754.
37. Gunnar T., Engblom C., Ariniemi K. Pressure-adjusted continual flow heart-cutting for the high throughput determination of amphetamine-type stimulant drugs in whole blood by fast multidimensional gas chromatography-mass spectrometry. J. Chromatogr. A 2007, 1166:171-180.
38. Kankaanpaa A., Gunnar T., Ariniemi K., Lillsunde P., Mykkanen S., Seppala T. Single-step procedure for gas chromatography-mass spectrometry screening and quantitative determination of amphetamine-type stimulants and related drugs in blood, serum, oral fluid and urine samples. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2004, 810:57-68.
39. Gunnar T., Ariniemi K., Lillsunde P. Determination of 14 benzodiazepines and hydroxy metabolites, zaleplon and zolpidem as tert-butyldimethylsilyl derivatives compared with other common silylating reagents in whole blood by gas chromatography-mass spectrometry. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2005, 818:175-189.
40. Schwilke E.W., Schwope D.M., Karschner E.L., Lowe R.H., Darwin W.D., Kelly D.L., Goodwin R.S., Gorelick D.A., Huestis M.A. Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC. Clin. Chem. 2009, 55:2180-2189.
41. Karjalainen K.K., Lintonen T.P., Impinen A.O., Lillsunde P.M., Ostamo A.I. Poly-drug findings in drugged driving cases during 1977-2007. J. Subst. Abuse 2010, 15:143-156.
42. Lillsunde P., Gunnar T. Drugs and driving; the finnish perspective. Bull. Narc. 2005, LVII:213-219.
43. Blencowe T., Raaska K., Lillsunde P. Benzodiazepines and sedative-hypnotics in blood of drivers under the influence and their association with other common illegal drug use and national sales figures. Ther. Drug Monit. 2011, 33:64-71.