Prospective evaluation of sedation-related adverse events in pediatric patients ventilated for acute respiratory failure

Critical Care Medicine

Volumn 40, Issue 4, 2012, Pages 1317-1323

  Grant, Mary Jo C ^a   Scoppettuolo, Lisa A ^b   Wypij, David ^b   Curley, Martha A Q ^c  

^a PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

adverse events; children; intensive care unit; medical errors; patient safety; sedation

Indexed keywords

ACUTE RESPIRATORY FAILURE; AGITATION; ANALGESIA; ARTIFICIAL VENTILATION; CHILD; EXTUBATION; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PAIN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; REVIEW; SEDATION; UNITED STATES;

ACUTE DISEASE; AIRWAY EXTUBATION; CATHETER-RELATED INFECTIONS; CHILD; CHILD, PRESCHOOL; CONSCIOUS SEDATION; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INTENSIVE CARE UNITS, PEDIATRIC; INTUBATION, INTRATRACHEAL; LENGTH OF STAY; MALE; PNEUMONIA, VENTILATOR-ASSOCIATED; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RESPIRATORY INSUFFICIENCY;

EID: 84858763069     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31823c8ae3     Document Type: Review

References (37)

1. Lubisch N, Roskos R, Sattler SM: Improving outcomes in pediatric procedural sedation. Jt Comm J Qual Patient Saf 2008; 34:192-195
2. Rothschild JM, Keohane CA, Cook EF, et al: A controlled trial of smart infusion pumps to improve medication safety in critically ill patients. Crit Care Med 2005; 33:533-540
3. Garrouste-Orgeas M, Timsit JF, Vesin A, et al: Selected medical errors in the intensive care unit: Results of the IATROREF study: Parts I and II. Am J Respir Crit Care Med 2010; 181:134-142
4. Agarwal S, Classen D, Larsen G, et al: Prevalence of adverse events in pediatric intensive care units in the United States. Pediatr Crit Care Med 2010; 11:568-578
5. Fiser DH, Long N, Roberson PK, et al: Relationship of pediatric overall performance category and pediatric cerebral performance category scores at pediatric intensive care unit discharge with outcome measures collected at hospital discharge and 1-and 6-month follow-up assessments. Crit Care Med 2000; 28:2616-2620
6. Pollack MM, Patel KM, Ruttimann UE: PRISM III: An updated Pediatric Risk of Mortality score. Crit Care Med 1996; 24:743-752
7. Merkel SI, Voepel-Lewis T, Shayevitz JR, et al: The FLACC: A behavioral scale for scoring postoperative pain in young children. Pediatr Nurs 1997; 23:293-297
8. Manworren RC, Hynan LS: Clinical validation of FLACC: Preverbal patient pain scale. Pediatr Nurs 2003; 29:140-146
9. Wong DL, Hockenberry-Eaton M, Wilson D, et al: Whaley and Wong's Nursing Care of Infants and Children. St. Louis, MO, Mosby, 1999
10. Solodiuk J, Curley MA: Pain assessment in nonverbal children with severe cognitive impairments: The Individualized Numeric Rating Scale (INRS). J Pediatr Nurs 2003; 18:295-299
11. Curley MA, Harris SK, Fraser KA, et al: State Behavioral Scale: A sedation assessment instrument for infants and young children supported on mechanical ventilation. Pediatr Crit Care Med 2006; 7:107-114
12. Franck LS, Harris SK, Soetenga DJ, et al: The Withdrawal Assessment Tool-1 (WAT-1): An assessment instrument for monitoring opioid and benzodiazepine withdrawal symptoms in pediatric patients. Pediatr Crit Care Med 2008; 9:573-580
13. Langley JM, Bradley JS: Defining pneumonia in critically ill infants and children. Pediatr Crit Care Med 2005; 6:S9-S13
14. Centers for Disease Control and Prevention: National Healthcare Safety Network Manual. Available at: http://www. cdc. gov/nhsn/PDFs/pscManual/ 17pscNosInfDef-current. pdf. Accessed January 5, 2011
15. Cook D, Walter S, Freitag A, et al: Adjudicating ventilator-associated pneumonia in a randomized trial of critically ill patients. J Crit Care 1998; 13:159-163
16. National Pressure Ulcer Advisory Panel: Pressure Ulcer Definitions and Descriptions 2007. Available at: http://www. npuap. org. Accessed August 20, 2010
17. Curley MA, Razmus IS, Roberts KE, et al: Predicting pressure ulcer risk in pediatric patients: The Braden Q Scale. Nurs Res 2003; 52:22-33
18. Thomas NJ, Shaffer ML, Willson DF, et al: Defining acute lung disease in children with the oxygenation saturation index. Pediatr Crit Care Med 2010; 11:12-17
19. Hayes RJ, Moulton LH: Cluster Randomised Trials. Boca Raton, FL, Chapman and Hall/CRC Press, 2009
20. Donner A, Klar N: Design and Analysis of Cluster Randomization Trials in Health Research. London, UK, Hodder Arnold, 2000
21. Ridout MS, Demétrio CG, Firth D: Estimating intraclass correlation for binary data. Biometrics 1999; 55:137-148
22. Hade EM, Murray DM, Pennell ML, et al: Intraclass correlation estimates for cancer screening outcomes: Estimates and applications in the design of group-randomized cancer screening studies. J Natl Cancer Inst Monogr 2010; 40:97-103
23. Ukoumunne OC: A comparison of confidence interval methods for the intraclass correlation coefficient in cluster randomized trials. Stat Med 2002; 21:3757-3774
24. Rhoney DH, Murry KR: National survey on the use of sedatives and neuromuscular blocking agents in the pediatric intensive care unit. Pediatr Crit Care Med 2002; 3: 129-133
25. Twite MD, Rashid A, Zuk J, et al: Sedation, analgesia, and neuromuscular blockade in the pediatric intensive care unit: Survey of fellowship training programs. Pediatr Crit Care Med 2004; 5:521-532
26. Marx CM, Rosenberg DI, Ambuel B, et al: Pediatric intensive care sedation: Survey of fellowship training programs. Pediatrics 1993; 91:369-378
27. Tobias JD: Tolerance, withdrawal, and physical dependency after long-term sedation and analgesia of children in the pediatric intensive care unit. Crit Care Med 2000; 28:2122-2132
28. Ream RS, Mackey K, Leet T, et al: Association of nursing workload and unplanned extubations in a pediatric intensive care unit. Pediatr Crit Care Med 2007; 8:366-371
29. Marcin JP, Rutan E, Rapetti PM, et al: Nurse staffing and unplanned extubation in the pediatric intensive care unit. Pediatr Crit Care Med 2005; 6:254-257
30. Popernack ML, Thomas NJ, Lucking SE: Decreasing unplanned extubations: Utilization of the Penn State Children's Hospital Sedation Algorithm. Pediatr Crit Care Med 2004; 5:58-62
31. Sadowski R, Dechert RE, Bandy KP, et al: Continuous quality improvement: Reducing unplanned extubations in a pediatric intensive care unit. Pediatrics 2004; 114: 628-632
32. Kurachek SC, Newth CJ, Quasney MW, et al: Extubation failure in pediatric intensive care: A multiple-center study of risk factors and outcomes. Crit Care Med 2003; 31:2657-2664
33. Baisch SD, Wheeler WB, Kurachek SC, et al: Extubation failure in pediatric intensive care incidence and outcomes. Pediatr Crit Care Med 2005; 6:312-318
34. Fontela PS, Piva JP, Garcia PC, et al: Risk factors for extubation failure in mechanically ventilated pediatric patients. Pediatr Crit Care Med 2005; 6:166-170
35. Farias JA, Alía I, Retta A, et al: An evaluation of extubation failure predictors in mechanically ventilated infants and children. Intensive Care Med 2002; 28:752-757
36. Venkatachalam V, Hendley JO, Willson DF: The diagnostic dilemma of ventilator-associated pneumonia in critically ill children. Pediatr Crit Care Med 2011; 12:286-296
37. Edwards JR, Peterson KD, Mu Y, et al: National Healthcare Safety Network (NHSN) report: Data summary for 2006 through 2008, issued December 2009. Am J Infect Control 2009; 37:783-805