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Volumn 31, Issue 2, 2012, Pages 261-266

Reduction of serum lipids by the intake of the extract of garlic fermented with Monascus pilosus: A randomized, double-blind, placebo-controlled clinical trial

Author keywords

Dimerumic acid; Garlic; Monacolin K; Monascus pilosus; Serum lipids

Indexed keywords

GARLIC EXTRACT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; TRIACYLGLYCEROL;

EID: 84858752849     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2011.10.008     Document Type: Article
Times cited : (24)

References (30)
  • 1
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival study (4S)
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival study (4S). Lancet 1994, 344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 2
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland coronary prevention study group
    • Shepherd J., Cobbe S.M., Ford I., Isles C.G., Lorimer A.R., MacFarlane P.W. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland coronary prevention study group. N Engl J Med 1995, 333:1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    MacFarlane, P.W.6
  • 3
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas coronary atherosclerosis prevention study
    • Downs J.R., Clearfield M., Weis S., Whitney E., Shapiro D.R., Beere P.A. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas coronary atherosclerosis prevention study. JAMA 1998, 279:1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3    Whitney, E.4    Shapiro, D.R.5    Beere, P.A.6
  • 4
    • 0041735202 scopus 로고    scopus 로고
    • A safety look at currently available statins
    • Moghadasian M.H. A safety look at currently available statins. Expert Opin Drug Saf 2002, 1:269-274.
    • (2002) Expert Opin Drug Saf , vol.1 , pp. 269-274
    • Moghadasian, M.H.1
  • 6
    • 2942705774 scopus 로고    scopus 로고
    • Safety of statins: focus on clinical pharmacokinetics and drug interactions
    • Bellosta S., Paoletti R., Corsini A. Safety of statins: focus on clinical pharmacokinetics and drug interactions. Circulation 2004, 109(23 Suppl. 1):III50-III57.
    • (2004) Circulation , vol.109 , Issue.23 SUPPL. 1
    • Bellosta, S.1    Paoletti, R.2    Corsini, A.3
  • 7
    • 0018592266 scopus 로고
    • Monacolin K, a new hypocholesterolemic agent produced by a monascus species
    • Endo A. Monacolin K, a new hypocholesterolemic agent produced by a monascus species. J Antibiot (Tokyo) 1979, 32:852-854.
    • (1979) J Antibiot (Tokyo) , vol.32 , pp. 852-854
    • Endo, A.1
  • 8
    • 0019195217 scopus 로고
    • Monacolin K, a new hypocholesterolemic agent that specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme a reductase
    • Endo A. Monacolin K, a new hypocholesterolemic agent that specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme a reductase. J Antibiot (Tokyo) 1980, 33:334-336.
    • (1980) J Antibiot (Tokyo) , vol.33 , pp. 334-336
    • Endo, A.1
  • 9
    • 0032898925 scopus 로고    scopus 로고
    • Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement
    • Heber D., Yip I., Ashley J.M., Elashoff D.A., Elashoff R.M., Go V.L. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr 1999, 69:231-236.
    • (1999) Am J Clin Nutr , vol.69 , pp. 231-236
    • Heber, D.1    Yip, I.2    Ashley, J.M.3    Elashoff, D.A.4    Elashoff, R.M.5    Go, V.L.6
  • 10
    • 34250741897 scopus 로고    scopus 로고
    • Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials
    • Liu J., Zhang J., Shi Y., Grimsgaard S., Alraek T., Fønnebø V. Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials. Chin Med 2006, 1:4.
    • (2006) Chin Med , vol.1 , pp. 4
    • Liu, J.1    Zhang, J.2    Shi, Y.3    Grimsgaard, S.4    Alraek, T.5    Fønnebø, V.6
  • 11
    • 79955972069 scopus 로고    scopus 로고
    • The treatment of hypercholesterolemic children: efficacy and safety of a combination of red yeast rice extract and policosanols
    • Guardamagna O., Abello F., Baracco V., Stasiowska B., Martino F. The treatment of hypercholesterolemic children: efficacy and safety of a combination of red yeast rice extract and policosanols. Nutr Metab Cardiovasc Dis 2011, 21:424-429.
    • (2011) Nutr Metab Cardiovasc Dis , vol.21 , pp. 424-429
    • Guardamagna, O.1    Abello, F.2    Baracco, V.3    Stasiowska, B.4    Martino, F.5
  • 12
    • 78049406766 scopus 로고    scopus 로고
    • Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study
    • Affuso F., Ruvolo A., Micillo F., Saccà L., Fazio S. Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. Nutr Metab Cardiovasc Dis 2010, 20:656-661.
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , pp. 656-661
    • Affuso, F.1    Ruvolo, A.2    Micillo, F.3    Saccà, L.4    Fazio, S.5
  • 13
    • 0035053811 scopus 로고    scopus 로고
    • An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents
    • Heber D., Lembertas A., Lu Q.Y., Bowerman S., Go V.L. An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents. J Altern Complement Med 2001, 7:133-139.
    • (2001) J Altern Complement Med , vol.7 , pp. 133-139
    • Heber, D.1    Lembertas, A.2    Lu, Q.Y.3    Bowerman, S.4    Go, V.L.5
  • 14
    • 67650564624 scopus 로고    scopus 로고
    • Safety and efficacy of red yeast rice (Monascus purpureus) as an alternative therapy for hyperlipidemia
    • Klimek M., Wang S., Ogunkanmi A. Safety and efficacy of red yeast rice (Monascus purpureus) as an alternative therapy for hyperlipidemia. PT 2009, 34:313-327.
    • (2009) PT , vol.34 , pp. 313-327
    • Klimek, M.1    Wang, S.2    Ogunkanmi, A.3
  • 15
    • 78049264831 scopus 로고    scopus 로고
    • Marked variability of monacolin levels in commercial red yeast rice products: buyer beware!
    • Gordon R.Y., Cooperman T., Obermeyer W., Becker D.J. Marked variability of monacolin levels in commercial red yeast rice products: buyer beware!. Arch Intern Med 2010, 25(170):1722-1727.
    • (2010) Arch Intern Med , vol.25 , Issue.170 , pp. 1722-1727
    • Gordon, R.Y.1    Cooperman, T.2    Obermeyer, W.3    Becker, D.J.4
  • 17
    • 21844451865 scopus 로고    scopus 로고
    • Health effects of garlic
    • Tattelman E. Health effects of garlic. Am Fam Physician 2005, 72:103-106.
    • (2005) Am Fam Physician , vol.72 , pp. 103-106
    • Tattelman, E.1
  • 18
    • 0033824315 scopus 로고    scopus 로고
    • The nutraceutical benefit, part IV: garlic
    • Sato T., Miyata G. The nutraceutical benefit, part IV: garlic. Nutrition 2000, 16:787-788.
    • (2000) Nutrition , vol.16 , pp. 787-788
    • Sato, T.1    Miyata, G.2
  • 19
    • 34948883590 scopus 로고    scopus 로고
    • Does garlic reduce risk of colorectal cancer? A systematic review
    • Ngo S.N., Williams D.B., Cobiac L., Head R.J. Does garlic reduce risk of colorectal cancer? A systematic review. J Nutr 2007, 137:2264-2269.
    • (2007) J Nutr , vol.137 , pp. 2264-2269
    • Ngo, S.N.1    Williams, D.B.2    Cobiac, L.3    Head, R.J.4
  • 20
    • 61349175255 scopus 로고    scopus 로고
    • Garlic supplementation and serum cholesterol: a meta-analysis
    • Khoo Y.S., Aziz Z. Garlic supplementation and serum cholesterol: a meta-analysis. J Clin Pharm Ther 2009, 34:133-145.
    • (2009) J Clin Pharm Ther , vol.34 , pp. 133-145
    • Khoo, Y.S.1    Aziz, Z.2
  • 22
    • 69249229873 scopus 로고    scopus 로고
    • The impact of garlic on lipid parameters: a systematic review and meta-analysis
    • Reinhart K.M., Talati R., White C.M., Coleman C.I. The impact of garlic on lipid parameters: a systematic review and meta-analysis. Nutr Res Rev 2009, 22:39-48.
    • (2009) Nutr Res Rev , vol.22 , pp. 39-48
    • Reinhart, K.M.1    Talati, R.2    White, C.M.3    Coleman, C.I.4
  • 23
    • 0029828635 scopus 로고    scopus 로고
    • A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids
    • Steiner M., Khan A.H., Holbert D., Lin R.I. A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids. Am J Clin Nutr 1996, 64:866-870.
    • (1996) Am J Clin Nutr , vol.64 , pp. 866-870
    • Steiner, M.1    Khan, A.H.2    Holbert, D.3    Lin, R.I.4
  • 24
    • 33746227530 scopus 로고    scopus 로고
    • Lipid-lowering effect of monascus garlic fermented extract (MGFE) in hyperlipidemic subjects
    • Sumioka I., Hayama M., Shimokawa Y., Shiraishi S., Tokunaga A. Lipid-lowering effect of monascus garlic fermented extract (MGFE) in hyperlipidemic subjects. Hiroshima J Med Sci. 2006, 55:59-64.
    • (2006) Hiroshima J Med Sci. , vol.55 , pp. 59-64
    • Sumioka, I.1    Hayama, M.2    Shimokawa, Y.3    Shiraishi, S.4    Tokunaga, A.5
  • 25
    • 38349150595 scopus 로고    scopus 로고
    • Experimental and clinical basis for the use of statins in patients with ischemic and nonischemic cardiomyopathy
    • Ramasubbu K., Estep J., White D.L., Deswal A., Mann D.L. Experimental and clinical basis for the use of statins in patients with ischemic and nonischemic cardiomyopathy. J Am Coll Cardiol 2008, 51:415-426.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 415-426
    • Ramasubbu, K.1    Estep, J.2    White, D.L.3    Deswal, A.4    Mann, D.L.5
  • 26
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M., Liao J.K. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol. 2001, 21:1712-1719.
    • (2001) Arterioscler Thromb Vasc Biol. , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 27
    • 0035192759 scopus 로고    scopus 로고
    • Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits
    • Rikitake Y., Kawashima S., Takeshita S., Yamashita T., Azumi H., Yasuhara M. Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits. Atherosclerosis 2001, 154:87-96.
    • (2001) Atherosclerosis , vol.154 , pp. 87-96
    • Rikitake, Y.1    Kawashima, S.2    Takeshita, S.3    Yamashita, T.4    Azumi, H.5    Yasuhara, M.6
  • 29
    • 0036497358 scopus 로고    scopus 로고
    • Dimerumic acid as an antioxidant from the mold, monascus anka: the inhibition mechanisms against lipid peroxidation and hemeprotein-mediated oxidation
    • Taira J., Miyagi C., Aniya Y. Dimerumic acid as an antioxidant from the mold, monascus anka: the inhibition mechanisms against lipid peroxidation and hemeprotein-mediated oxidation. Biochem Pharmacol 2002, 63:1019-1026.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1019-1026
    • Taira, J.1    Miyagi, C.2    Aniya, Y.3
  • 30
    • 45849086588 scopus 로고    scopus 로고
    • Dimerumic acid protected oxidative stress-induced cytotoxicity in isolated rat hepatocytes
    • Yamashiro J., Shiraishi S., Fuwa T., Horie T. Dimerumic acid protected oxidative stress-induced cytotoxicity in isolated rat hepatocytes. Cell Biol Toxicol 2008, 24:283-290.
    • (2008) Cell Biol Toxicol , vol.24 , pp. 283-290
    • Yamashiro, J.1    Shiraishi, S.2    Fuwa, T.3    Horie, T.4


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