High prevalence of polymorphism and low activity of thiopurine methyltransferase in patients with inflammatory bowel disease

European Journal of Internal Medicine

Volumn 23, Issue 3, 2012, Pages 273-277

  Larussa, Tiziana ^a   Suraci, Evelina ^a   Lentini, Margherita ^a   Nazionale, Immacolata ^a   Gallo, Luigia ^a   Abenavoli, Ludovico ^a   Imeneo, Maria ^a   Costanzo, Francesco Saverio ^a   Cuda, Giovanni ^a   Luzza, Francesco ^a  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Azathioprine; Crohn's disease; Inflammatory bowel diseases; Thiopurines; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; MESALAZINE; SALAZOSULFAPYRIDINE; THIOPURINE METHYLTRANSFERASE;

ADULT; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DNA POLYMORPHISM; ENTERITIS; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; GENOTYPE PHENOTYPE CORRELATION; HOMOZYGOSITY; HUMAN; IMMUNOASSAY; MAJOR CLINICAL STUDY; MALE; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SMOKING; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; AGED; COLITIS, ULCERATIVE; CROHN DISEASE; DRUG HYPERSENSITIVITY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; METHYLTRANSFERASES; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC; PREVALENCE; PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS; YOUNG ADULT;

EID: 84858750740     PISSN: 09536205     EISSN: 18790828     Source Type: Journal    
DOI: 10.1016/j.ejim.2011.12.002     Document Type: Article

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