The membranotropic activity of N-terminal peptides from the pore-forming proteins sticholysin I and II is modulated by hydrophobic and electrostatic interactions as well as lipid composition

Journal of Biosciences

Volumn 36, Issue 5, 2011, Pages 781-791

  Ros, Uris ^a   Pedrera, Lohans ^a   Díaz, Daylín ^a   De Karam, Juan C ^a   Sudbrack, Tatiane P ^b   Valiente, Pedro A ^a   Martínez, Diana ^a   Cilli, Eduardo M ^c   Pazos, Fabiola ^a   Itri, Rosangela ^b   Lanio, Maria E ^a   Schreier, Shirley ^b   Álvarez, Carlos ^a  

^a UNIVERSITY OF HAVANA   (Cuba)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Actinoporin; Hemolytic peptide; Permeabilizing activity; Pore forming toxin; Sticholysin

Indexed keywords

LIPOSOME; PHOSPHATIDYLCHOLINE; PORE FORMING CYTOTOXIC PROTEIN; SPHINGOMYELIN; STICHOLYSIN I; STICHOLYSIN II; UNCLASSIFIED DRUG; COELENTERATE VENOM; MEMBRANE LIPID; ORGANIC COMPOUND; PEPTIDE FRAGMENT; STYCHOLYSIN I;

AMINO ACID; HYDROPHOBICITY; INVERTEBRATE; LIPID; MEMBRANE; PEPTIDE; PROTEIN; TOXIN;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ERYTHROCYTE; HYDROPHOBICITY; LIPID BILAYER; LIPID COMPOSITION; LIPID MEMBRANE; MEMBRANE PERMEABILITY; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN BINDING; PROTEIN INTERACTION; STATIC ELECTRICITY; STICHODACTYLA HELIANTHUS; AMINO ACID SEQUENCE; CHEMICAL PHENOMENA; CHEMISTRY; MOLECULAR GENETICS; PERMEABILITY; SYNTHESIS;

ACTINIARIA; STICHODACTYLA HELIANTHUS;

AMINO ACID SEQUENCE; CNIDARIAN VENOMS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPID BILAYERS; MEMBRANE LIPIDS; MOLECULAR SEQUENCE DATA; ORGANIC CHEMICALS; PEPTIDE FRAGMENTS; PERMEABILITY; PROTEIN BINDING; UNILAMELLAR LIPOSOMES;

EID: 84858744175     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-011-9156-4     Document Type: Article

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