Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism

Biological Psychiatry

Volumn 71, Issue 5, 2012, Pages 392-402

  Fernandez, Thomas V ^a,b   Sanders, Stephan J ^a,b   Yurkiewicz, Ilana R ^a   Ercan Sencicek, A Gulhan ^a,b   Kim, Young Shin ^a   Fishman, Daniel O ^a   Raubeson, Melanie J ^a   Song, Youeun ^a   Yasuno, Katsuhito ^b   Ho, Winson S C ^b   Bilguvar, Kaya ^b   Glessner, Joseph ^c   Chu, Su Hee ^d   Leckman, James F ^a   King, Robert A ^a   Gilbert, Donald L ^e   Heiman, Gary A ^f   Tischfield, Jay A ^f   Hoekstra, Pieter J ^g   Devlin, Bernie ^d   Hakonarson, Hakon ^c   Mane, Shrikant M ^b   Gnel, Murat ^b   State, Matthew W ^a,b   more..

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CINCINNATI   (United States)

^f RUTGERS UNIVERSITY   (United States)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Autism; CNV; copy number variation; GABA; histamine; Tourette syndrome

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; HISTAMINE RECEPTOR;

ARTICLE; AUTISM; CELL ADHESION; CHILD PARENT RELATION; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE DISRUPTION; GENE MAPPING; GENETIC VARIABILITY; GENOTYPE; GILLES DE LA TOURETTE SYNDROME; HUMAN; INTELLECTUAL IMPAIRMENT; MAJOR CLINICAL STUDY; NERVE FIBER; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; RISK ASSESSMENT; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SYNAPSE;

ADULT; AUTISTIC DISORDER; CASE-CONTROL STUDIES; CHILD; DNA COPY NUMBER VARIATIONS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INTELLECTUAL DISABILITY; RECEPTORS, GABA; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; TOURETTE SYNDROME;

EID: 84858737859     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.09.034     Document Type: Article

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