Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

Journal of Bone and Mineral Research

Volumn 27, Issue 4, 2012, Pages 835-847

  Roelofs, Anke J ^a   Stewart, Charlotte A ^a   Sun, Shuting ^b   Błazewska, Katarzyna M ^b,c   Kashemirov, Boris A ^b   McKenna, Charles E ^b   Russell, R Graham G ^d,e   Rogers, Michael J ^a   Lundy, Mark W ^f   Ebetino, Frank H ^g   Coxon, Fraser P ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF SHEFFIELD   (United Kingdom)

^f INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Warner Chilcott (Ireland) Ltd   (Ireland)

Author keywords

bisphosphonates; bone affinity; bone resorption; distribution; osteocytes

Indexed keywords

3 PEHPC; BISPHOSPHONIC ACID DERIVATIVE; DEOXY RISEDRONATE; RISEDRONIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BONE MINERAL; BONE MINERALIZATION; CONTROLLED STUDY; CORTICAL BONE; DENTIN; DRUG BINDING; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG LABELING; DRUG PENETRATION; FLUORESCENCE ANALYSIS; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSTEOCYTE; OSTEOID; OSTEOLYSIS; PERIOSTEUM; RAT; SURFACE PROPERTY;

ANIMALS; BONE AND BONES; BONE RESORPTION; CALCIFICATION, PHYSIOLOGIC; DIPHOSPHONATES; FLUORESCENT DYES; MALE; MICE; OSTEOCYTES; PERIOSTEUM; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SURFACE PROPERTIES;

EID: 84858720359     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1543     Document Type: Article

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