Quantification of phenylalanine hydroxylase activity by isotope-dilution liquid chromatography-electrospray ionization tandem mass spectrometry

Molecular Genetics and Metabolism

Volumn 105, Issue 4, 2012, Pages 559-565

  Heintz, Caroline ^a   Troxler, Heinz ^a   Martinez, Aurora ^b   Thöny, Beat ^a,c,d   Blau, Nenad ^a,c,d,e  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b UNIVERSITY OF BERGEN   (Norway)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d Research Center for Children RCC   (Switzerland)

^e UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

BH 4; Hyperphenylalaninemia; PAH; Phenylketonuria; PKU; Tetrahydrobiopterin

Indexed keywords

PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; TETRAHYDROBIOPTERIN; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CELL LINE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; GENE MUTATION; KIDNEY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; LIVER; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BIOPTERIN; BRAIN; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, LIQUID; COS CELLS; HUMANS; ISOTOPE LABELING; KIDNEY; LIVER; MICE; MUTATION; PHENOTYPE; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; PHENYLKETONURIAS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TYROSINE;

EUKARYOTA; MUS;

EID: 84858700380     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2011.12.025     Document Type: Article

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