Synergistic targeting of α vβ 3 integrin and galectin-1 with heteromultivalent paramagnetic liposomes for combined MR imaging and treatment of angiogenesis

Nano Letters

Volumn 10, Issue 1, 2010, Pages 52-58

  Kluza, Ewelina ^a   Van Der Schaft, Daisy W J ^a   Hautvast, Petra A I ^b   Mulder, Willem J M ^c   Mayo, Kevin H ^d   Griffioen, Arjan W ^a,e   Strijkers, Gustav J ^a   Nicolay, Klaas ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Angiogenesis; Anti angiogenic therapy; Magnetic resonance imaging; Molecular imaging; Synergistic targeting

Indexed keywords

ANGIOGENESIS; ANTI-ANGIOGENIC THERAPY; FUNCTIONALIZED; GALECTIN-1; IN-VITRO; INTEGRINS; MOLECULAR IMAGING; MR IMAGING; OPTICAL TECHNIQUE;

LIPOSOMES; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; PHOSPHOLIPIDS;

LIGANDS;

ANGIOGENESIS INHIBITOR; GALECTIN 1; LIGAND; LIPOSOME; NANOPARTICLE; PEPTIDE; VITRONECTIN RECEPTOR;

ARTICLE; CELL CULTURE; CHEMISTRY; CONFOCAL MICROSCOPY; FLUORESCENCE MICROSCOPY; HUMAN; MAGNETISM; METHODOLOGY; NANOTECHNOLOGY; NEOVASCULARIZATION (PATHOLOGY); NUCLEAR MAGNETIC RESONANCE IMAGING;

ANGIOGENESIS INHIBITORS; CELLS, CULTURED; GALECTIN 1; HUMANS; INTEGRIN ALPHAVBETA3; LIGANDS; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MAGNETICS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; NANOTECHNOLOGY; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES;

EID: 74849112431     PISSN: 15306984     EISSN: None     Source Type: Journal    
DOI: 10.1021/nl902659g     Document Type: Article

References (35)

1. Cormode, D. P.; Skajaa, T.; Fayad, Z. A.; Mulder, W. J. M. Arterioscler Thromb. Vasc. Biol. 2009, 29, 992-1000.
2. Nunn, A. D.; Linder, K. E.; Tweedle, M. F. Q. L. Nucl. Med. 1997, 41, 155-162.
3. Sosnovik, D. E.; Weissleder, R. Curr. Opin. Biotechnol. 2007, 18, 4-10.
4. Strijkers, G. J.; Mulder, W. J. M.; van Tilborg, G. A. F.; Nicolay, K. Anti-Cancer Agents Med. Chem. 2007, 7, 291-305.
5. McCarthy, J. R.; Kelly, K. A.; Sun, E. Y.; Weissleder, R. Nanomed. 2007, 2, 153-167.
6. Mulder, W. J. M.; Strijkers, G. J.; van Tilborg, G. A. F.; Griffioen, A. W.; Nicolay, K. NMR Biomed. 2006, 19, 142-164.
7. Schirner, M.; Menrad, A.; Stephens, A.; Frenzel, T.; Hauff, P.; Licha, K. Ann. N.Y. Acad. Sci. 2004, 1014, 67-75.
8. Rehman, S.; Jayson, G. C. Oncologist 2005, 10, 92-103.
9. Ferrara, N.; Kerbel, R. S. Nature 2005, 438, 967-974.
10. Weidner, N.; Semple, J. P.; Welch, W. R.; Folkman, J. N. Engl. J. Med. 1991, 324, 1-8.
11. Fox, S. B.; Harris, A. L. Invest. New Drugs 1997, 15, 15-28.
12. Pasqualini, R.; Arap, W.; McDonald, D. M. Trends Mol. Med. 2002, 8, 563-571.
13. Schlingemann, R. O.; Rietveld, F. J.; Kwaspen, F.; van deKerkhof, P. C.; de Waal, R. M.; Ruiter, D. J. Am. J. Pathol. 1991, 138, 1335-1347.
14. Adams, R. H.; Alitalo, K. Nat. Rev. Mol. Cell Biol. 2007, 8, 464-478.
15. Avraamides, C. J.; Garmy-Susini, B.; Varner, J. A. Nat. Rev. Cancer 2008, 8, 604-617.
16. Laginha, K.; Mumbengegwi, D.; Allen, T. Biochim. Biophys. Acta 2005, 1711, 25-32.
17. Saul, J. M.; Annapragada, A. V.; Bellamkonda, R. V. J. Controlled Release 2006, 114, 277-287.
18. McAteer, M. A.; Schneider, J. E.; Ali, Z. A.; Warrick, N.; Bursill, C. A.; von zur Muhlen, C.; Greaves, D. R.; Neubauer, S.; Channon, K. M.; Choudhury, R. P. Arterioscler Thromb. Vasc. Biol. 2008, 28, 77-83.
19. Willmann, J. K.; Lutz, A. M.; Paulmurugan, R.; Patel, M. R.; Chu, P.; Rosenberg, J.; Gambhir, S. S. Radiology 2008, 248, 936-944.
20. Cheresh, D. A. Proc. Natl. Acad. Sci. U.S.A. 1987, 84, 6471-6475.
21. Ruoslahti, E.; Pierschbacher, M. D. Cell 1986, 44, 517-518.
22. Brooks, P. C.; Clark, R. A.; Cheresh, D. A. Science 1994, 264, 569-571.
23. Sipkins, D. A.; Cheresh, D. A.; Kazemi, M. R.; Nevin, L. M.; Bednarski, M. D.; Li, K. C. Nat. Med. 1998, 4, 623-626.
24. Haubner, R.; Wester, H. J.; Weber, W. A.; Mang, C.; Ziegler, S. I.; Goodman, S. L.; Senekowitsch-Schmidtke, R.; Kessler, H. Schwaiger M. Cancer Res. 2001, 61, 1781-1785.
25. Leong-Poi, H.; Christiansen, J.; Klibanov, A. L.; Kaul, S.; Lindner, J. R. Circulation 2003, 107, 455-460.
26. Mulder, W. J. M.; Strijkers, G. J.; Habets, J. W.; Bleeker, E. J. W.; van der Schaft, D. W. J.; Storm, C.; Koning, G. A.; Griffioen, A. W.; Nicolay, K. FASEB J. 2005, 19, 2008-2010.
27. Thijssen, V. L. J. L.; Postel, R.; Brandwijk, R. J. M. G. E.; Dings, R. P. M.; Nesmelova, I.; Satijn, S.; Verhofstad, N.; Nakabeppu, Y.; Baum, L. C.; Bakkers, J.; Mayo, K. H.; Poirier, F.; Griffioen, A. W. Prpc. Natl. Acad. Sci. U.S.A. 2006, 103, 15975-15980.
28. Griffioen, A. W.; van der Schaft, D. W.; Barendsz-Janson, A. F.; Cox, A.; Boudier, H. A. S.; Hillen, H. F.; Mayo, K. H. Biochem. J. 2001, 354, 233-242.
29. van der Schaft, D. W. J.; Dings, R. P. M.; de Lussanet, Q. G.; van Eijk, L. I.; Nap, A. W.; Beets-Tan, R. G. H.; Steege, J. C. A. B.-T.; Wagstaff, J.; Mayo, K. H.; Griffioen, A. W. FASEB J. 2002, 16, 1991-1993.
30. Brandwijk, R. J. M. G. E.; Mulder, W.J. M.; Nicolay, K.; Mayo, K. H.; Thijssen, V. L. J. L.; Griffioen, A. W. Bioconiua. Chem. 2007, 18, 785-790.
31. Lim, E. H.; Danthi, N.; Bednarski, M.; Li, K. C. P. Nanomedicine 2005, 1, 110-114.
32. Garanger, E.; Boturyn, D.; Dumy, P. Anti-Cancer Agents Med. Chem. 2007, 7, 552-558.
33. Josan, J.; Vagner, J.; Handl, H.; Sankaranarayanan, R.; Gillies, R.; Hruby, V. Int. J. Pept. Res. Ther. 2008, 14, 293-300.
34. Toews, M. L.; Bylund, D. B. Proc. Am. Thorac. Soc. 2005, 2, 282-9, discussion 290-291
35. Vagner, J.; Xu, L.; Handl, H. L.; Josan, J. S.; Morse, D. L.; Mash, E. A.; Gillies, R. J.; Hruby, V. J. Angew. Chem., Int. Ed. 2008, 47, 1685-1688.