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Volumn 16, Issue 3, 2012, Pages 409-414

New synthetic route to a dipeptidyl peptidase-4 inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

ECONOMICAL IMPACT; LEAVING GROUPS; METHYL ESTERS; OVERALL COSTS; SYNTHETIC ROUTES;

EID: 84858691372     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200309z     Document Type: Article
Times cited : (12)

References (19)
  • 2
    • 84858694795 scopus 로고    scopus 로고
    • US Patent 2005/0256310 A1
    • Hulin, B.; Piotrowski, D. W. US Patent 2005/0256310 A1, 2005; 24 pp.
    • (2005) , pp. 24
    • Hulin, B.1    Piotrowski, D.W.2
  • 15
    • 84858694794 scopus 로고    scopus 로고
    • The reaction reaches approximately 95% conversion in 6 h with nosylate 11 versus 18 h for 6c
    • The reaction reaches approximately 95% conversion in 6 h with nosylate 11 versus 18 h for 6c.
  • 18
    • 0003586590 scopus 로고    scopus 로고
    • 6 th ed. Butterworth-Heinemann: Oxford
    • HOBT hydrate was used. CAUTION: Vacuum-drying of HOBT while heating can generate a violent explosion! See: Urben, P. G. In Brethericks Handbook of Reactive Chemical Hazards, 6 th ed.; Butterworth-Heinemann: Oxford, 1999; p 746.
    • (1999) Brethericks Handbook of Reactive Chemical Hazards , pp. 746
    • Urben, P.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.