Population bulk segregant mapping uncovers resistance mutations and the mode of action of a chitin synthesis inhibitor in arthropods

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 12, 2012, Pages 4407-4412

  Van Leeuwen, Thomas ^a   Demaeght, Peter ^a   Osborne, Edward J ^b   Dermauw, Wannes ^a   Gohlke, Simon ^c   Nauen, Ralf ^d   Grbić, Miodrag ^e,f   Tirry, Luc ^a   Merzendorfer, Hans ^c   Clark, Richard M ^b  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF OSNABRÜCK   (Germany)

^d BAYER CROPSCIENCE AG   (Germany)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

^f Ctra Burgos Km 6   (Spain)

Author keywords

Cuticle; Development; Diflubenzuron; Insecticide; Toxicology

Indexed keywords

ACARICIDE; CHITIN SYNTHASE; CHITIN SYNTHASE 1; ETOXAZOLE; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; BULKED SEGREGANT ANALYSIS; CONTROLLED STUDY; ENZYME SYNTHESIS; GENE LOCUS; GENE MUTATION; GENETIC COMPLEMENTATION; GENOME; HIGH THROUGHPUT SEQUENCING; MITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECESSIVE GENE; TETRANYCHUS URTICAE;

ANIMALS; ARTHROPODS; CHITIN; CHITIN SYNTHASE; CRYOPRESERVATION; DIFLUBENZURON; DRUG RESISTANCE; FEMALE; FUNGAL PROTEINS; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; INSECTICIDES; MALE; MODELS, BIOLOGICAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; OXAZOLES; POPULATION DYNAMICS; PROTEIN STRUCTURE, TERTIARY; UREA;

ARTHROPODA; HEXAPODA; TETRANYCHIDAE; TETRANYCHUS URTICAE;

EID: 84858674174     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200068109     Document Type: Article

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