Monte Carlo modeling and in-vivo imaging at the Heidelberg Ion Beam Therapy Center

IEEE Nuclear Science Symposium Conference Record

Volumn , Issue , 2011, Pages 2795-2799

  Parodi, Katia ^a   Bauer, Julia ^a   Kurz, Christopher ^a   Mairani, Andrea ^a,b   Sommerer, Florian ^a   Unholtz, Daniel ^a   Haberer, Thomas ^a   Debus, Jürgen ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b Centro Nazionale Adroterapia Oncologica CNAO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CLINICAL RESEARCH; ION BEAMS; IONS; IRRADIATION; MEDICAL IMAGING; MONTE CARLO METHODS;

CLINICAL APPLICATION; CLINICAL OPERATIONS; ION BEAM THERAPIES; MONTE CARLO CALCULATION; OPTIMAL EXPLOITATION; PATIENT REPOSITIONING; POST-RADIATION TREATMENT; REPEATED MEASUREMENTS;

PROTON BEAM THERAPY;

EID: 84858667567     PISSN: 10957863     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NSSMIC.2011.6153641     Document Type: Conference Paper

References (21)

1. G. Battistoni, S. Muraro, P.R. Sala, F. Cerutti, A. Ferrari, S. Roesler, A. Fassò and J. Ranft, "The FLUKA code: Description and benchmarking,"in Proceedings of the Hadronic Shower Simulation Workshop 2006, Fermilab 6-8 September 2006, in: M. Albrow and R. Raja, AIP Conference Proceeding 896, 2007, pp. 31-49
2. A. Ferrari, P.R. Sala, A. Fassò and J. Ranft, "FLUKA: a multi-particle transport code," in CERN Yellow Report CERN 2005-10; INFN/TC\-05/11, SLAC-R-773, Geneva, 2005
3. K. Parodi, A. Mairani, S. Brons, J. Naumann, F. Sommerer and T. Haberer, "The application of the FLUKA Monte Carlo code to basic data generation for clinical treatment planning of scanned proton and carbon ion therapy," in Book of Abstracts from European Workshop on Monte Carlo Treatment Planning, Cardiff, UK, 19th-21st October, 2009, available at http://www.mctp2009.org
4. M. Krämer, O. Jäkel, T. Haberer, G. Kraft, D. Schardt and U. Weber, "Treatment planning for heavy-ion radiotherapy: physical beam model and dose optimization," Phys. Med. Biol., vol. 45, pp. 3299-17, 2000
5. U. Weber and G. Kraft, "Design and construction of a ripple filter for a smoothed depth dose distribution in conformal particle therapy," Phys. Med. Biol., vol. 44, pp. 2765-75, 1999 (Pubitemid 29529358)
6. A. Mairani, S. Brons, F. Cerutti, A. Ferrari, K. Parodi, P. Sala, M. Scholz and F. Sommerer, "From nuclear reactions modeling to biological effective dose calculations: the FLUKA Monte Carlo code for carbon ion therapy," in Book of Abstracts from European Workshop on Monte Carlo Treatment Planning, Cardiff, UK, 19th-21st October, 2009, available at http://www.mctp2009.org
7. E. Pedroni, S. Scheib, T. Böhringer, A. Coray, M. Grossmann, S. Lin and A. Lomax, "Experimental characterization and physical modelling of the dose distribution of scanned proton pencil beams," Phys. Med. Biol., vol. 50, pp. 541-61, 2005 (Pubitemid 40297924)
8. J. Schwaab, S. Brons, J. Fieres and K. Parodi, "Experimental characterization of lateral profiles of scanned proton and carbon ion pencil beams for improved beam models in ion therapy treatment planning," Phys. Med. Biol. (accepted for publication)
9. L. Hong, M. Goitein, M. Bucciolini, R. Comiskey, B. Gottschalk, S. Rosenthal, C. Serago and M. Urie, "A pencil beam algorithm for proton dose calculations," Phys. Med. Biol., vol. 41, pp. 1305-36, 1996
10. K. Parodi, A. Ferrari, F. Sommerer and H. Paganetti, "Clinical CT-based calculations of dose and positron emitter distributions in proton therapy using the FLUKA Monte Carlo code," Phys. Med. Biol., vol. 52, pp. 3369-87, 2007 (Pubitemid 46830631)
11. A. Mairani, S. Brons, F. Cerutti, A. Ferrari, E. Gadioli, K. Parodi, M. Scholz, F. Sommerer, "Clinical Calculations of physical and biological effective dose distributions in proton and carbon ion therapy using the FLUKA Monte Carlo code," Conference Record of the IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany, 2008, pp. 5612-15
12. D. Unholtz, F. Sommerer, J. Bauer, D. von Straaten, T. Haberer, J. Debus and K. Parodi, "Post-therapeutical β+-activity measurements in comparison to simulations towards in-vivo verification of ion beam therapy," Conference Record of the IEEE Nuclear Science Symposium and Medical Imaging Conference in Valencia, Spain, 2011
13. K. Parodi, H. Paganetti, H.A. Shih, S. Michaud, J.S. Loeffler, T.F. DeLaney, N.J. Liebsch, J.E. Munzenrider, A.J. Fischman, A. Knopf and T. Bortfeld, "Patient study on in-vivo verification of beam delivery and range using PET/CT imaging after proton therapy," Int. J. Rad. Onc. Biol. Phys., vol. 68, pp. 920-34, 2007 (Pubitemid 46818759)
14. S.E. Combs, U. Haberkorn, J. Debus and K. Parodi, "PET-Bildgebung für die Protonen- und Schwerionentherapie: Hintergrund, Entwicklungen und klinische Implementierung", in the "Der Nuklearrnediziner" CME Thieme, issue 2/11, 2011
15. 12C beams: experiments and FLUKA simulations for homogeneous targets,"Phys. Med. Biol., vol. 54, pp. 3979-996, 2009
16. J. Bauer, D. Unholtz, F. Sommerer, T. Haberer, S.E. Combs, J. Debus, K. Parodi, "Paving the way towards clinical PET-based in-vivo treatment verification at HIT," in Book of Abstracts, PTCOG 50 meeting in Philadelphia, USA, May 8-14, 2011
17. K. Parodi, H. Paganetti, E. Cascio, J. Flanz, A. Bonab, N. Alpert, K. Lohmann, T. Bortfeld, "PET/CT imaging for treatment verification after proton therapy - a study with plastic phantoms and metallic implants," Med. Phys., vol. 34, pp. 419-35, 2007 (Pubitemid 46185120)
18. W. Schneider, T. Bortfeld and W. Schlegel, "Correlation between CT numbers and tissue parameters needed for Monte Carlo simulations of clinical dose distributions," Phys. Med. Biol., vol. 45, pp. 459-478, 2000 (Pubitemid 30096775)
19. A. Mairani, S. Brons, F. Cerutti, A. Fassò, A. Ferrari, M. Krämer, K. Parodi, M. Scholz, F. Sommerer, "The FLUKA Monte Carlo code coupled with the local effect model for biological calculations in carbon ion therapy," Phys. Med. Biol., vol. 55, pp. 4273-89, 2010
20. A. Knopf, K. Parodi, T. Bortfeld, H. Shih and H. Paganetti, "Systematic analysis of biological and physical limitations of proton beam range verification with offline PET/CT scans," Phys. Med. Biol., vol. 54, pp. 4477-95, 2009
21. S. Espana, X. Zhu, J. Daartz, G. El Fakhri, T. Bortfeld and H. Paganetti, "The reliability of proton-nuclear interaction cross-section data to predict proton-induced PET images in proton therapy," Phys. Med. Biol., vol. 56, pp. 2687-2698, 2011