Ablation of the pro-apoptotic protein bax protects mice from glucocorticoid-induced bone growth impairment

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Zaman, Farasat ^a   Chrysis, Dionisios ^a   Huntjens, Kirsten ^a   Fadeel, Bengt ^b   Sävendahl, Lars ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; DEXAMETHASONE; PROTEIN BAX; SMALL INTERFERING RNA; BAX PROTEIN, HUMAN; BAX PROTEIN, MOUSE; GLUCOCORTICOID;

ABLATION THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAX GENE; BONE GROWTH; CARTILAGE CELL; CELL PROLIFERATION; CELL STRAIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG INDUCED DISEASE; EX VIVO STUDY; FEMALE; GENE ACTIVATION; GENE SILENCING; GENE TARGETING; GLUCOCORTICOID INDUCED BONE GROWTH IMPAIRMENT; GROWTH PLATE; MALE; MARKER GENE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROTEIN SECRETION; PROTEIN TARGETING; ADOLESCENT; ANIMAL; CELL LINE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; OBESITY; OSTEOPOROSIS; PATHOLOGY;

MUS;

ADOLESCENT; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; CHONDROCYTES; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; GROWTH PLATE; HUMANS; MALE; MICE; MICE, MUTANT STRAINS; OBESITY; OSTEOPOROSIS;

EID: 84858606456     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033168     Document Type: Article

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