Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver

Journal of Biological Chemistry

Volumn 287, Issue 12, 2012, Pages 9240-9249

  Iwamura, Atsushi ^a   Fukami, Tatsuki ^a   Higuchi, Ryota ^a   Nakajima, Miki ^a   Yokoi, Tsuyoshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE METABOLITES; AMINO ACID SEQUENCE; CHROMATOGRAPHIC PURIFICATION; CYTOSOLS; GLUCURONIDASE; GLUCURONIDATION; GLUCURONIDES; HUMAN LIVER; IMMUNOBLOT ANALYSIS; MYCOPHENOLATE MOFETIL; MYCOPHENOLIC ACIDS; PROTEIN EXPRESSIONS; PURIFIED ENZYME;

AMINO ACIDS; CADMIUM CHLORIDE; CHROMATOGRAPHIC ANALYSIS; COPPER COMPOUNDS; HYDROLASES; METABOLISM; METABOLITES; PHENOLS; PURIFICATION;

BIOMOLECULES;

4 NITROPHENYLPHOSPHATASE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); ALPHA BETA HYDROLASE DOMAIN CONTAINING 10 PROTEIN; CADMIUM CHLORIDE; CUPRIC CHLORIDE; DRUG METABOLITE; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE 2B7; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID ACYL GLUCURONIDE; SILVER NITRATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG DEGLUCURONIDATION; DRUG TRANSFORMATION; ENZYME PURIFICATION; HUMAN; IMMUNOBLOTTING; LIVER CYTOSOL; LIVER HOMOGENATE; LIVER MICROSOME; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

ESTERASES; GLUCURONIDES; HUMANS; KINETICS; LIVER; MYCOPHENOLIC ACID;

EID: 84858600981     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.271288     Document Type: Article

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