-
1
-
-
83955165970
-
Changing demographics of valvular heart disease and impact on surgical and transcatheter valve therapies
-
A. Vahanian, B. Iung, D. Himbert, and P. Nataf Changing demographics of valvular heart disease and impact on surgical and transcatheter valve therapies Int J Cardiovasc Imaging 2011
-
(2011)
Int J Cardiovasc Imaging
-
-
Vahanian, A.1
Iung, B.2
Himbert, D.3
Nataf, P.4
-
2
-
-
79952183726
-
Epidemiology of valvular heart disease in the adult
-
B. Iung, and A. Vahanian Epidemiology of valvular heart disease in the adult Nat Rev Cardiol 8 2011 162 172
-
(2011)
Nat Rev Cardiol
, vol.8
, pp. 162-172
-
-
Iung, B.1
Vahanian, A.2
-
3
-
-
0016271607
-
Observations on the effect of age on the severity of heart valve lesions in the dog
-
J.C. Whitney Observations on the effect of age on the severity of heart valve lesions in the dog J Small Anim Pract 15 1974 511 522
-
(1974)
J Small Anim Pract
, vol.15
, pp. 511-522
-
-
Whitney, J.C.1
-
4
-
-
70350430448
-
Guidelines for the diagnosis and treatment of canine chronic valvular heart disease
-
C. Atkins, J. Bonagura, S. Ettinger, P. Fox, S. Gordon, J. Haggstrom, R. Hamlin, B. Keene, V. Luis-Fuentes, and R. Stepien Guidelines for the diagnosis and treatment of canine chronic valvular heart disease J Vet Intern Med 23 2009 1142 1150
-
(2009)
J Vet Intern Med
, vol.23
, pp. 1142-1150
-
-
Atkins, C.1
Bonagura, J.2
Ettinger, S.3
Fox, P.4
Gordon, S.5
Haggstrom, J.6
Hamlin, R.7
Keene, B.8
Luis-Fuentes, V.9
Stepien, R.10
-
5
-
-
50249092065
-
Interstitial cells from dogs with naturally occurring myxomatous mitral valve disease undergo phenotype transformation
-
discussion 412
-
S. Disatian, E.J. Ehrhart 3rd, S. Zimmerman, and E.C. Orton Interstitial cells from dogs with naturally occurring myxomatous mitral valve disease undergo phenotype transformation J Heart Valve Dis 17 2008 402 411 discussion 412
-
(2008)
J Heart Valve Dis
, vol.17
, pp. 402-411
-
-
Disatian, S.1
Ehrhart III, E.J.2
Zimmerman, S.3
Orton, E.C.4
-
6
-
-
0019947447
-
"Myxomatous" mitral valves: Collagen dissolution as the primary defect
-
B.D. King, M.A. Clark, N. Baba, J.W. Kilman, and C.F. Wooley "Myxomatous" mitral valves: collagen dissolution as the primary defect Circulation 66 1982 288 296
-
(1982)
Circulation
, vol.66
, pp. 288-296
-
-
King, B.D.1
Clark, M.A.2
Baba, N.3
Kilman, J.W.4
Wooley, C.F.5
-
7
-
-
0035526212
-
Mechanical properties of myxomatous mitral valves
-
J.E. Barber, F.K. Kasper, N.B. Ratliff, D.M. Cosgrove, B.P. Griffin, and I. Vesely Mechanical properties of myxomatous mitral valves J Thorac Cardiovasc Surg 122 2001 955 962
-
(2001)
J Thorac Cardiovasc Surg
, vol.122
, pp. 955-962
-
-
Barber, J.E.1
Kasper, F.K.2
Ratliff, N.B.3
Cosgrove, D.M.4
Griffin, B.P.5
Vesely, I.6
-
8
-
-
0035923477
-
Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves
-
E. Rabkin, M. Aikawa, J.R. Stone, Y. Fukumoto, P. Libby, and F.J. Schoen Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves Circulation 104 2001 2525 2532
-
(2001)
Circulation
, vol.104
, pp. 2525-2532
-
-
Rabkin, E.1
Aikawa, M.2
Stone, J.R.3
Fukumoto, Y.4
Libby, P.5
Schoen, F.J.6
-
9
-
-
33646924001
-
Bmp and fgf regulatory pathways control cell lineage diversification of heart valve precursor cells
-
J. Lincoln, C.M. Alfieri, and K.E. Yutzey Bmp and fgf regulatory pathways control cell lineage diversification of heart valve precursor cells Dev Biol 292 2006 292 302
-
(2006)
Dev Biol
, vol.292
, pp. 292-302
-
-
Lincoln, J.1
Alfieri, C.M.2
Yutzey, K.E.3
-
10
-
-
33745102721
-
Hearts and bones: Shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development
-
J. Lincoln, A.W. Lange, and K.E. Yutzey Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development Dev Biol 294 2006 292 302
-
(2006)
Dev Biol
, vol.294
, pp. 292-302
-
-
Lincoln, J.1
Lange, A.W.2
Yutzey, K.E.3
-
12
-
-
33644831129
-
Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: Influence of shear stress
-
J.T. Butcher, S. Tressel, T. Johnson, D. Turner, G. Sorescu, H. Jo, and R.M. Nerem Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress Arterioscler Thromb Vasc Biol 26 2006 69 77
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 69-77
-
-
Butcher, J.T.1
Tressel, S.2
Johnson, T.3
Turner, D.4
Sorescu, G.5
Jo, H.6
Nerem, R.M.7
-
13
-
-
33646564670
-
Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: Effects of steady shear stress
-
J.T. Butcher, and R.M. Nerem Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress Tissue Eng 12 2006 905 915
-
(2006)
Tissue Eng
, vol.12
, pp. 905-915
-
-
Butcher, J.T.1
Nerem, R.M.2
-
14
-
-
3943101416
-
Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments
-
J.T. Butcher, A.M. Penrod, A.J. Garcia, and R.M. Nerem Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments Arterioscler Thromb Vasc Biol 24 2004 1429 1434
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1429-1434
-
-
Butcher, J.T.1
Penrod, A.M.2
Garcia, A.J.3
Nerem, R.M.4
-
15
-
-
77950906118
-
Tryptophan hydroxylase 1 expression is increased in phenotype-altered canine and human degenerative myxomatous mitral valves
-
S. Disatian, C. Lacerda, and E.C. Orton Tryptophan hydroxylase 1 expression is increased in phenotype-altered canine and human degenerative myxomatous mitral valves J Heart Valve Dis 19 2010 71 78
-
(2010)
J Heart Valve Dis
, vol.19
, pp. 71-78
-
-
Disatian, S.1
Lacerda, C.2
Orton, E.C.3
-
16
-
-
36348976915
-
The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology
-
A.C. Liu, V.R. Joag, and A.I. Gotlieb The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology Am J Pathol 171 2007 1407 1418
-
(2007)
Am J Pathol
, vol.171
, pp. 1407-1418
-
-
Liu, A.C.1
Joag, V.R.2
Gotlieb, A.I.3
-
17
-
-
73349142054
-
Insights into serotonin signaling mechanisms associated with canine degenerative mitral valve disease
-
M.A. Oyama, and R.J. Levy Insights into serotonin signaling mechanisms associated with canine degenerative mitral valve disease J Vet Intern Med 24 2010 27 36
-
(2010)
J Vet Intern Med
, vol.24
, pp. 27-36
-
-
Oyama, M.A.1
Levy, R.J.2
-
19
-
-
70350402108
-
Serum serotonin concentrations in dogs with degenerative mitral valve disease
-
J.W. Arndt, C.A. Reynolds, G.E. Singletary, J.M. Connolly, R.J. Levy, and M.A. Oyama Serum serotonin concentrations in dogs with degenerative mitral valve disease J Vet Intern Med 23 2009 1208 1213
-
(2009)
J Vet Intern Med
, vol.23
, pp. 1208-1213
-
-
Arndt, J.W.1
Reynolds, C.A.2
Singletary, G.E.3
Connolly, J.M.4
Levy, R.J.5
Oyama, M.A.6
-
20
-
-
1542319112
-
Identification of surface morphologic changes in the mitral valve leaflets and chordae tendineae of dogs with myxomatous degeneration
-
B.M. Corcoran, A. Black, H. Anderson, J.D. McEwan, A. French, P. Smith, and C. Devine Identification of surface morphologic changes in the mitral valve leaflets and chordae tendineae of dogs with myxomatous degeneration Am J Vet Res 65 2004 198 206
-
(2004)
Am J Vet Res
, vol.65
, pp. 198-206
-
-
Corcoran, B.M.1
Black, A.2
Anderson, H.3
McEwan, J.D.4
French, A.5
Smith, P.6
Devine, C.7
-
21
-
-
0024308276
-
Scanning electron microscopy of operatively excised severely regurgitant floppy mitral valves
-
P.D. Stein, C.H. Wang, J.M. Riddle, H.N. Sabbah, D.J. Magilligan Jr., and E.T. Hawkins Scanning electron microscopy of operatively excised severely regurgitant floppy mitral valves Am J Cardiol 64 1989 392 394
-
(1989)
Am J Cardiol
, vol.64
, pp. 392-394
-
-
Stein, P.D.1
Wang, C.H.2
Riddle, J.M.3
Sabbah, H.N.4
Magilligan, Jr.D.J.5
Hawkins, E.T.6
-
23
-
-
0033039361
-
Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the framingham heart study)
-
J.P. Singh, J.C. Evans, D. Levy, M.G. Larson, L.A. Freed, D.L. Fuller, B. Lehman, and E.J. Benjamin Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the framingham heart study) Am J Cardiol 83 1999 897 902
-
(1999)
Am J Cardiol
, vol.83
, pp. 897-902
-
-
Singh, J.P.1
Evans, J.C.2
Levy, D.3
Larson, M.G.4
Freed, L.A.5
Fuller, D.L.6
Lehman, B.7
Benjamin, E.J.8
-
24
-
-
3843094165
-
Etiology of valvular heart disease
-
H. Boudoulas Etiology of valvular heart disease Expert Rev Cardiovasc Ther 1 2003 523 532
-
(2003)
Expert Rev Cardiovasc Ther
, vol.1
, pp. 523-532
-
-
Boudoulas, H.1
-
25
-
-
37149042730
-
Floppy mitral valve/mitral valve prolapse and genetics
-
C. Yosefy, and A. Ben Barak Floppy mitral valve/mitral valve prolapse and genetics J Heart Valve Dis 16 2007 590 595
-
(2007)
J Heart Valve Dis
, vol.16
, pp. 590-595
-
-
Yosefy, C.1
Ben Barak, A.2
-
26
-
-
36949032340
-
Age-related changes in collagen synthesis and turnover in porcine heart valves
-
E.H. Stephens, and K.J. Grande-Allen Age-related changes in collagen synthesis and turnover in porcine heart valves J Heart Valve Dis 16 2007 672 682
-
(2007)
J Heart Valve Dis
, vol.16
, pp. 672-682
-
-
Stephens, E.H.1
Grande-Allen, K.J.2
-
27
-
-
44649176440
-
Reversible secretion of glycosaminoglycans and proteoglycans by cyclically stretched valvular cells in 3d culture
-
V. Gupta, J.A. Werdenberg, B.D. Lawrence, J.S. Mendez, E.H. Stephens, and K.J. Grande-Allen Reversible secretion of glycosaminoglycans and proteoglycans by cyclically stretched valvular cells in 3d culture Ann Biomed Eng 36 2008 1092 1103
-
(2008)
Ann Biomed Eng
, vol.36
, pp. 1092-1103
-
-
Gupta, V.1
Werdenberg, J.A.2
Lawrence, B.D.3
Mendez, J.S.4
Stephens, E.H.5
Grande-Allen, K.J.6
-
28
-
-
84858450730
-
Static and cyclic tensile strain induce myxomatous effector proteins and serotonin in canine mitral valve
-
C.M.R. Lacerda, H.B. MacLea, J. Kisiday, and E.C. Orton Static and cyclic tensile strain induce myxomatous effector proteins and serotonin in canine mitral valve J Vet Cardiol 2012
-
(2012)
J Vet Cardiol
-
-
Lacerda, C.M.R.1
MacLea, H.B.2
Kisiday, J.3
Orton, E.C.4
-
29
-
-
54449089154
-
The effects of mitral regurgitation alone are sufficient for leaflet remodeling
-
E.H. Stephens, T.C. Nguyen, A. Itoh, N.B. Ingels Jr., D.C. Miller, and K.J. Grande-Allen The effects of mitral regurgitation alone are sufficient for leaflet remodeling Circulation 118 2008 S243 S249
-
(2008)
Circulation
, vol.118
-
-
Stephens, E.H.1
Nguyen, T.C.2
Itoh, A.3
Ingels, Jr.N.B.4
Miller, D.C.5
Grande-Allen, K.J.6
-
30
-
-
0037414862
-
Synthesis of serotonin by a second tryptophan hydroxylase isoform
-
D.J. Walther, J.U. Peter, S. Bashammakh, H. Hortnagl, M. Voits, H. Fink, and M. Bader Synthesis of serotonin by a second tryptophan hydroxylase isoform Science 299 2003 76
-
(2003)
Science
, vol.299
, pp. 76
-
-
Walther, D.J.1
Peter, J.U.2
Bashammakh, S.3
Hortnagl, H.4
Voits, M.5
Fink, H.6
Bader, M.7
-
31
-
-
33745124642
-
5-hydroxytryptamine in the cardiovascular system: Focus on the serotonin transporter (sert)
-
W. Ni, and S.W. Watts 5-hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (sert) Clin Exp Pharmacol Physiol 33 2006 575 583
-
(2006)
Clin Exp Pharmacol Physiol
, vol.33
, pp. 575-583
-
-
Ni, W.1
Watts, S.W.2
-
32
-
-
0036899272
-
Serotonin mechanisms in heart valve disease ii: The 5-ht2 receptor and its signaling pathway in aortic valve interstitial cells
-
J. Xu, B. Jian, R. Chu, Z. Lu, Q. Li, J. Dunlop, S. Rosenzweig-Lipson, P. McGonigle, R.J. Levy, and B. Liang Serotonin mechanisms in heart valve disease ii: the 5-ht2 receptor and its signaling pathway in aortic valve interstitial cells Am J Pathol 161 2002 2209 2218
-
(2002)
Am J Pathol
, vol.161
, pp. 2209-2218
-
-
Xu, J.1
Jian, B.2
Chu, R.3
Lu, Z.4
Li, Q.5
Dunlop, J.6
Rosenzweig-Lipson, S.7
McGonigle, P.8
Levy, R.J.9
Liang, B.10
-
33
-
-
0030039838
-
Ras involvement in signal transduction by the serotonin 5-ht2b receptor
-
J.M. Launay, G. Birraux, D. Bondoux, J. Callebert, D.S. Choi, S. Loric, and L. Maroteaux Ras involvement in signal transduction by the serotonin 5-ht2b receptor J Biol Chem 271 1996 3141 3147
-
(1996)
J Biol Chem
, vol.271
, pp. 3141-3147
-
-
Launay, J.M.1
Birraux, G.2
Bondoux, D.3
Callebert, J.4
Choi, D.S.5
Loric, S.6
Maroteaux, L.7
-
34
-
-
4644248958
-
Rho kinase-induced nuclear translocation of erk1/erk2 in smooth muscle cell mitogenesis caused by serotonin
-
Y. Liu, Y.J. Suzuki, R.M. Day, and B.L. Fanburg Rho kinase-induced nuclear translocation of erk1/erk2 in smooth muscle cell mitogenesis caused by serotonin Circ Res 95 2004 579 586
-
(2004)
Circ Res
, vol.95
, pp. 579-586
-
-
Liu, Y.1
Suzuki, Y.J.2
Day, R.M.3
Fanburg, B.L.4
-
35
-
-
33644865034
-
Serotonin transporter mechanisms and cardiac disease
-
R.J. Levy Serotonin transporter mechanisms and cardiac disease Circulation 113 2006 2 4
-
(2006)
Circulation
, vol.113
, pp. 2-4
-
-
Levy, R.J.1
-
36
-
-
20144389923
-
Long-term serotonin administration induces heart valve disease in rats
-
B.I. Gustafsson, K. Tommeras, I. Nordrum, J.P. Loennechen, A. Brunsvik, E. Solligard, R. Fossmark, I. Bakke, U. Syversen, and H. Waldum Long-term serotonin administration induces heart valve disease in rats Circulation 111 2005 1517 1522
-
(2005)
Circulation
, vol.111
, pp. 1517-1522
-
-
Gustafsson, B.I.1
Tommeras, K.2
Nordrum, I.3
Loennechen, J.P.4
Brunsvik, A.5
Solligard, E.6
Fossmark, R.7
Bakke, I.8
Syversen, U.9
Waldum, H.10
-
37
-
-
77950954498
-
Dose dependency and reversibility of serotonin-induced valvular heart disease in rats
-
S. Droogmans, B. Roosens, B. Cosyns, C. Degaillier, S. Hernot, C. Weytjens, C. Garbar, V. Caveliers, M. Pipeleers-Marichal, P.R. Franken, A. Bossuyt, D. Schoors, T. Lahoutte, and G. Van Camp Dose dependency and reversibility of serotonin-induced valvular heart disease in rats Cardiovasc Toxicol 9 2009 134 141
-
(2009)
Cardiovasc Toxicol
, vol.9
, pp. 134-141
-
-
Droogmans, S.1
Roosens, B.2
Cosyns, B.3
Degaillier, C.4
Hernot, S.5
Weytjens, C.6
Garbar, C.7
Caveliers, V.8
Pipeleers-Marichal, M.9
Franken, P.R.10
Bossuyt, A.11
Schoors, D.12
Lahoutte, T.13
Van Camp, G.14
-
38
-
-
33845974147
-
Valvular heart disease and the use of dopamine agonists for parkinson's disease
-
R. Zanettini, A. Antonini, G. Gatto, R. Gentile, S. Tesei, and G. Pezzoli Valvular heart disease and the use of dopamine agonists for parkinson's disease N Engl J Med 356 2007 39 46
-
(2007)
N Engl J Med
, vol.356
, pp. 39-46
-
-
Zanettini, R.1
Antonini, A.2
Gatto, G.3
Gentile, R.4
Tesei, S.5
Pezzoli, G.6
-
39
-
-
67649379367
-
Serotonergic drugs and valvular heart disease
-
R.B. Rothman, and M.H. Baumann Serotonergic drugs and valvular heart disease Expert Opin Drug Saf 8 2009 317 329
-
(2009)
Expert Opin Drug Saf
, vol.8
, pp. 317-329
-
-
Rothman, R.B.1
Baumann, M.H.2
-
40
-
-
33646929505
-
Lisuride, a dopamine receptor agonist with 5-ht2b receptor antagonist properties: Absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-ht2b receptor agonism in cardiac valvular fibrosis
-
C. Hofmann, U. Penner, R. Dorow, H.H. Pertz, S. Jahnichen, R. Horowski, K.P. Latte, D. Palla, and B. Schurad Lisuride, a dopamine receptor agonist with 5-ht2b receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-ht2b receptor agonism in cardiac valvular fibrosis Clin Neuropharmacol 29 2006 80 86
-
(2006)
Clin Neuropharmacol
, vol.29
, pp. 80-86
-
-
Hofmann, C.1
Penner, U.2
Dorow, R.3
Pertz, H.H.4
Jahnichen, S.5
Horowski, R.6
Latte, K.P.7
Palla, D.8
Schurad, B.9
-
41
-
-
33845986031
-
Dopamine agonists and the risk of cardiac-valve regurgitation
-
R. Schade, F. Andersohn, S. Suissa, W. Haverkamp, and E. Garbe Dopamine agonists and the risk of cardiac-valve regurgitation N Engl J Med 356 2007 29 38
-
(2007)
N Engl J Med
, vol.356
, pp. 29-38
-
-
Schade, R.1
Andersohn, F.2
Suissa, S.3
Haverkamp, W.4
Garbe, E.5
-
42
-
-
0033989494
-
Possible role of valvular serotonin 5-ht(2b) receptors in the cardiopathy associated with fenfluramine
-
L.W. Fitzgerald, T.C. Burn, B.S. Brown, J.P. Patterson, M.H. Corjay, P.A. Valentine, J.H. Sun, J.R. Link, I. Abbaszade, J.M. Hollis, B.L. Largent, P.R. Hartig, G.F. Hollis, P.C. Meunier, A.J. Robichaud, and D.W. Robertson Possible role of valvular serotonin 5-ht(2b) receptors in the cardiopathy associated with fenfluramine Mol Pharmacol 57 2000 75 81
-
(2000)
Mol Pharmacol
, vol.57
, pp. 75-81
-
-
Fitzgerald, L.W.1
Burn, T.C.2
Brown, B.S.3
Patterson, J.P.4
Corjay, M.H.5
Valentine, P.A.6
Sun, J.H.7
Link, J.R.8
Abbaszade, I.9
Hollis, J.M.10
Largent, B.L.11
Hartig, P.R.12
Hollis, G.F.13
Meunier, P.C.14
Robichaud, A.J.15
Robertson, D.W.16
-
43
-
-
0034610435
-
Evidence for possible involvement of 5-ht(2b) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications
-
R.B. Rothman, M.H. Baumann, J.E. Savage, L. Rauser, A. McBride, S.J. Hufeisen, and B.L. Roth Evidence for possible involvement of 5-ht(2b) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications Circulation 102 2000 2836 2841
-
(2000)
Circulation
, vol.102
, pp. 2836-2841
-
-
Rothman, R.B.1
Baumann, M.H.2
Savage, J.E.3
Rauser, L.4
McBride, A.5
Hufeisen, S.J.6
Roth, B.L.7
-
44
-
-
33644865941
-
Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice
-
A. Mekontso-Dessap, F. Brouri, O. Pascal, P. Lechat, N. Hanoun, L. Lanfumey, I. Seif, N. Benhaiem-Sigaux, M. Kirsch, M. Hamon, S. Adnot, and S. Eddahibi Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice Circulation 113 2006 81 89
-
(2006)
Circulation
, vol.113
, pp. 81-89
-
-
Mekontso-Dessap, A.1
Brouri, F.2
Pascal, O.3
Lechat, P.4
Hanoun, N.5
Lanfumey, L.6
Seif, I.7
Benhaiem-Sigaux, N.8
Kirsch, M.9
Hamon, M.10
Adnot, S.11
Eddahibi, S.12
-
45
-
-
46649092122
-
5-hydroxytryptamine (5ht)-induced valvulopathy: Compositional valvular alterations are associated with 5ht2b receptor and 5ht transporter transcript changes in sprague-dawley rats
-
C.S. Elangbam, L.E. Job, L.M. Zadrozny, J.C. Barton, L.W. Yoon, L.D. Gates, and N. Slocum 5-hydroxytryptamine (5ht)-induced valvulopathy: compositional valvular alterations are associated with 5ht2b receptor and 5ht transporter transcript changes in sprague-dawley rats Exp Toxicol Pathol 60 2008 253 262
-
(2008)
Exp Toxicol Pathol
, vol.60
, pp. 253-262
-
-
Elangbam, C.S.1
Job, L.E.2
Zadrozny, L.M.3
Barton, J.C.4
Yoon, L.W.5
Gates, L.D.6
Slocum, N.7
-
46
-
-
33747793077
-
Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease
-
M.A. Oyama, and S.V. Chittur Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease Am J Vet Res 67 2006 1307 1318
-
(2006)
Am J Vet Res
, vol.67
, pp. 1307-1318
-
-
Oyama, M.A.1
Chittur, S.V.2
-
47
-
-
65349154575
-
Autocrine serotonin and transforming growth factor beta 1 signaling mediates spontaneous myxomatous mitral valve disease
-
S. Disatian, and E.C. Orton Autocrine serotonin and transforming growth factor beta 1 signaling mediates spontaneous myxomatous mitral valve disease J Heart Valve Dis 18 2009 44 51
-
(2009)
J Heart Valve Dis
, vol.18
, pp. 44-51
-
-
Disatian, S.1
Orton, E.C.2
-
48
-
-
78649908999
-
Serotonin transmembrane transporter is down-regulated in late-stage canine degenerative mitral valve disease
-
S.M. Scruggs, S. Disatian, and E.C. Orton Serotonin transmembrane transporter is down-regulated in late-stage canine degenerative mitral valve disease J Vet Cardiol 12 2010 163 169
-
(2010)
J Vet Cardiol
, vol.12
, pp. 163-169
-
-
Scruggs, S.M.1
Disatian, S.2
Orton, E.C.3
-
49
-
-
3042838388
-
Latent tgf-beta binding proteins: Extracellular matrix association and roles in tgf-beta activation
-
M. Hyytiainen, C. Penttinen, and J. Keski-Oja Latent tgf-beta binding proteins: extracellular matrix association and roles in tgf-beta activation Crit Rev Clin Lab Sci 41 2004 233 264
-
(2004)
Crit Rev Clin Lab Sci
, vol.41
, pp. 233-264
-
-
Hyytiainen, M.1
Penttinen, C.2
Keski-Oja, J.3
-
50
-
-
33645806742
-
Fibrosis in heart disease: Understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia
-
R. Khan, and R. Sheppard Fibrosis in heart disease: understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia Immunology 118 2006 10 24
-
(2006)
Immunology
, vol.118
, pp. 10-24
-
-
Khan, R.1
Sheppard, R.2
-
51
-
-
0029551805
-
Identification of a member of the mapkkk family as a potential mediator of tgf-beta signal transduction
-
K. Yamaguchi, K. Shirakabe, H. Shibuya, K. Irie, I. Oishi, N. Ueno, T. Taniguchi, E. Nishida, and K. Matsumoto Identification of a member of the mapkkk family as a potential mediator of tgf-beta signal transduction Science 270 1995 2008 2011
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
52
-
-
0027393417
-
Involvement of transforming growth factor-beta in the formation of fibrotic lesions in carcinoid heart disease
-
J. Waltenberger, L. Lundin, K. Oberg, E. Wilander, K. Miyazono, C.H. Heldin, and K. Funa Involvement of transforming growth factor-beta in the formation of fibrotic lesions in carcinoid heart disease Am J Pathol 142 1993 71 78
-
(1993)
Am J Pathol
, vol.142
, pp. 71-78
-
-
Waltenberger, J.1
Lundin, L.2
Oberg, K.3
Wilander, E.4
Miyazono, K.5
Heldin, C.H.6
Funa, K.7
-
53
-
-
0037314647
-
Progression of aortic valve stenosis: Tgf-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis
-
discussion 465-456
-
B. Jian, N. Narula, Q.Y. Li, E.R. Mohler 3rd, and R.J. Levy Progression of aortic valve stenosis: Tgf-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis Ann Thorac Surg 75 2003 457 465 discussion 465-456
-
(2003)
Ann Thorac Surg
, vol.75
, pp. 457-465
-
-
Jian, B.1
Narula, N.2
Li, Q.Y.3
Mohler III, E.R.4
Levy, R.J.5
-
54
-
-
40549085331
-
Overexpression of transforming growth factor-beta 1 in the valvular fibrosis of chronic rheumatic heart disease
-
L. Kim, K. Kim do, W.I. Yang, D.H. Shin, I.M. Jung, H.K. Park, and B.C. Chang Overexpression of transforming growth factor-beta 1 in the valvular fibrosis of chronic rheumatic heart disease J Korean Med Sci 23 2008 41 48
-
(2008)
J Korean Med Sci
, vol.23
, pp. 41-48
-
-
Kim, L.1
Kim Do, K.2
Yang, W.I.3
Shin, D.H.4
Jung, I.M.5
Park, H.K.6
Chang, B.C.7
-
55
-
-
48949099429
-
Expression of transforming growth factor-beta1, -beta2 and -beta3 in normal and diseased canine mitral valves
-
H. Aupperle, I. Marz, J. Thielebein, and H.A. Schoon Expression of transforming growth factor-beta1, -beta2 and -beta3 in normal and diseased canine mitral valves J Comp Pathol 139 2008 97 107
-
(2008)
J Comp Pathol
, vol.139
, pp. 97-107
-
-
Aupperle, H.1
Marz, I.2
Thielebein, J.3
Schoon, H.A.4
-
56
-
-
79951915137
-
Effects of transforming growth factor-beta3 and matrix metalloproteinase-3 on the pathogenesis of chronic mitral valvular disease in dogs
-
K. Obayashi, S. Miyagawa-Tomita, H. Matsumoto, H. Koyama, T. Nakanishi, and H. Hirose Effects of transforming growth factor-beta3 and matrix metalloproteinase-3 on the pathogenesis of chronic mitral valvular disease in dogs Am J Vet Res 72 2011 194 202
-
(2011)
Am J Vet Res
, vol.72
, pp. 194-202
-
-
Obayashi, K.1
Miyagawa-Tomita, S.2
Matsumoto, H.3
Koyama, H.4
Nakanishi, T.5
Hirose, H.6
-
57
-
-
4043127381
-
Valvular myofibroblast activation by transforming growth factor-beta: Implications for pathological extracellular matrix remodeling in heart valve disease
-
G.A. Walker, K.S. Masters, D.N. Shah, K.S. Anseth, and L.A. Leinwand Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease Circ Res 95 2004 253 260
-
(2004)
Circ Res
, vol.95
, pp. 253-260
-
-
Walker, G.A.1
Masters, K.S.2
Shah, D.N.3
Anseth, K.S.4
Leinwand, L.A.5
-
58
-
-
34548485827
-
Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast
-
W.D. Merryman, H.D. Lukoff, R.A. Long, G.C. Engelmayr Jr., R.A. Hopkins, and M.S. Sacks Synergistic effects of cyclic tension and transforming growth factor-beta1 on the aortic valve myofibroblast Cardiovasc Pathol 16 2007 268 276
-
(2007)
Cardiovasc Pathol
, vol.16
, pp. 268-276
-
-
Merryman, W.D.1
Lukoff, H.D.2
Long, R.A.3
Engelmayr, Jr.G.C.4
Hopkins, R.A.5
Sacks, M.S.6
-
59
-
-
0036898211
-
Serotonin mechanisms in heart valve disease i: Serotonin-induced up-regulation of transforming growth factor-beta1 via g-protein signal transduction in aortic valve interstitial cells
-
B. Jian, J. Xu, J. Connolly, R.C. Savani, N. Narula, B. Liang, and R.J. Levy Serotonin mechanisms in heart valve disease i: serotonin-induced up-regulation of transforming growth factor-beta1 via g-protein signal transduction in aortic valve interstitial cells Am J Pathol 161 2002 2111 2121
-
(2002)
Am J Pathol
, vol.161
, pp. 2111-2121
-
-
Jian, B.1
Xu, J.2
Connolly, J.3
Savani, R.C.4
Narula, N.5
Liang, B.6
Levy, R.J.7
-
60
-
-
0033143762
-
Serotonin 5-ht2a receptor induces tgf-beta1 expression in mesangial cells via erk: Proliferative and fibrotic signals
-
J.S. Grewal, Y.V. Mukhin, M.N. Garnovskaya, J.R. Raymond, and E.L. Greene Serotonin 5-ht2a receptor induces tgf-beta1 expression in mesangial cells via erk: proliferative and fibrotic signals Am J Physiol 276 1999 F922 F930
-
(1999)
Am J Physiol
, vol.276
-
-
Grewal, J.S.1
Mukhin, Y.V.2
Garnovskaya, M.N.3
Raymond, J.R.4
Greene, E.L.5
-
61
-
-
70149088960
-
Heart valve development: Regulatory networks in development and disease
-
M.D. Combs, and K.E. Yutzey Heart valve development: regulatory networks in development and disease Circ Res 105 2009 408 421
-
(2009)
Circ Res
, vol.105
, pp. 408-421
-
-
Combs, M.D.1
Yutzey, K.E.2
-
62
-
-
33846610695
-
The next frontier in cardiovascular developmental biology-an integrated approach to adult disease?
-
R.R. Markwald, and J.T. Butcher The next frontier in cardiovascular developmental biology-an integrated approach to adult disease? Nat Clin Pract Cardiovasc Med 4 2007 60 61
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 60-61
-
-
Markwald, R.R.1
Butcher, J.T.2
-
64
-
-
33646466212
-
Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation
-
F.C. Caira, S.R. Stock, T.G. Gleason, E.C. McGee, J. Huang, R.O. Bonow, T.C. Spelsberg, P.M. McCarthy, S.H. Rahimtoola, and N.M. Rajamannan Human degenerative valve disease is associated with up-regulation of low-density lipoprotein receptor-related protein 5 receptor-mediated bone formation J Am Coll Cardiol 47 2006 1707 1712
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 1707-1712
-
-
Caira, F.C.1
Stock, S.R.2
Gleason, T.G.3
McGee, E.C.4
Huang, J.5
Bonow, R.O.6
Spelsberg, T.C.7
McCarthy, P.M.8
Rahimtoola, S.H.9
Rajamannan, N.M.10
-
65
-
-
0037163093
-
Wnt-3a enhances bone morphogenetic protein-2-mediated chondrogenesis of murine c3h10t1/2 mesenchymal cells
-
L. Fischer, G. Boland, and R.S. Tuan Wnt-3a enhances bone morphogenetic protein-2-mediated chondrogenesis of murine c3h10t1/2 mesenchymal cells J Biol Chem 277 2002 30870 30878
-
(2002)
J Biol Chem
, vol.277
, pp. 30870-30878
-
-
Fischer, L.1
Boland, G.2
Tuan, R.S.3
-
66
-
-
0037739654
-
Cellular signaling in developmental chondrogenesis: N-cadherin, wnts, and bmp-2
-
R.S. Tuan Cellular signaling in developmental chondrogenesis: N-cadherin, wnts, and bmp-2 J Bone Jt Surg Am 85-A Suppl. 2 2003 137 141
-
(2003)
J Bone Jt Surg Am
, vol.85 A
, Issue.SUPPL. 2
, pp. 137-141
-
-
Tuan, R.S.1
-
67
-
-
13444296903
-
Multiple functions of bmps in chondrogenesis
-
B.S. Yoon, and K.M. Lyons Multiple functions of bmps in chondrogenesis J Cell Biochem 93 2004 93 103
-
(2004)
J Cell Biochem
, vol.93
, pp. 93-103
-
-
Yoon, B.S.1
Lyons, K.M.2
-
68
-
-
84858441350
-
Canine and human degenerative mitral valve disease mimic chondrogenesis
-
H.B. MacLea, R. LCM, J.D. Kisiday, and E.C. Orton Canine and human degenerative mitral valve disease mimic chondrogenesis J Vet Intern Med 25 2011 648
-
(2011)
J Vet Intern Med
, vol.25
, pp. 648
-
-
MacLea, H.B.1
Lcm, R.2
Kisiday, J.D.3
Orton, E.C.4
-
69
-
-
8444251784
-
The wnt signaling pathway in development and disease
-
C.Y. Logan, and R. Nusse The wnt signaling pathway in development and disease Annu Rev Cell Dev Biol 20 2004 781 810
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
70
-
-
42949117323
-
Roles of wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair
-
C.E. Macsai, B.K. Foster, and C.J. Xian Roles of wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair J Cell Physiol 215 2008 578 587
-
(2008)
J Cell Physiol
, vol.215
, pp. 578-587
-
-
MacSai, C.E.1
Foster, B.K.2
Xian, C.J.3
-
71
-
-
0033864484
-
Dual roles of wnt signaling during chondrogenesis in the chicken limb
-
C. Hartmann, and C.J. Tabin Dual roles of wnt signaling during chondrogenesis in the chicken limb Development 127 2000 3141 3159
-
(2000)
Development
, vol.127
, pp. 3141-3159
-
-
Hartmann, C.1
Tabin, C.J.2
-
72
-
-
14844284570
-
Genetic disorders of the lrp5-wnt signalling pathway affecting the skeleton
-
M.A. Koay, and M.A. Brown Genetic disorders of the lrp5-wnt signalling pathway affecting the skeleton Trends Mol Med 11 2005 129 137
-
(2005)
Trends Mol Med
, vol.11
, pp. 129-137
-
-
Koay, M.A.1
Brown, M.A.2
-
73
-
-
77950641024
-
Lrp5 and bone formation: A serotonin-dependent pathway
-
V.K. Yadav, and P. Ducy Lrp5 and bone formation: a serotonin-dependent pathway Ann N Y Acad Sci 1192 2010 103 109
-
(2010)
Ann N y Acad Sci
, vol.1192
, pp. 103-109
-
-
Yadav, V.K.1
Ducy, P.2
-
74
-
-
73549103784
-
Mechanisms of aortic valve calcification: The ldl-density-radius theory: A translation from cell signaling to physiology
-
N.M. Rajamannan Mechanisms of aortic valve calcification: the ldl-density-radius theory: a translation from cell signaling to physiology Am J Physiol Heart Circ Physiol 298 2010 H5 15
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. 5-15
-
-
Rajamannan, N.M.1
-
75
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
S. Artavanis-Tsakonas, M.D. Rand, and R.J. Lake Notch signaling: cell fate control and signal integration in development Science 284 1999 770 776
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
76
-
-
9144246932
-
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
-
L.A. Timmerman, J. Grego-Bessa, A. Raya, E. Bertran, J.M. Perez-Pomares, J. Diez, S. Aranda, S. Palomo, F. McCormick, J.C. Izpisua-Belmonte, and J.L. de la Pompa Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation Genes Dev 18 2004 99 115
-
(2004)
Genes Dev
, vol.18
, pp. 99-115
-
-
Timmerman, L.A.1
Grego-Bessa, J.2
Raya, A.3
Bertran, E.4
Perez-Pomares, J.M.5
Diez, J.6
Aranda, S.7
Palomo, S.8
McCormick, F.9
Izpisua-Belmonte, J.C.10
De La Pompa, J.L.11
-
78
-
-
24644467759
-
Mutations in notch1 cause aortic valve disease
-
V. Garg, A.N. Muth, J.F. Ransom, M.K. Schluterman, R. Barnes, I.N. King, P.D. Grossfeld, and D. Srivastava Mutations in notch1 cause aortic valve disease Nature 437 2005 270 274
-
(2005)
Nature
, vol.437
, pp. 270-274
-
-
Garg, V.1
Muth, A.N.2
Ransom, J.F.3
Schluterman, M.K.4
Barnes, R.5
King, I.N.6
Grossfeld, P.D.7
Srivastava, D.8
-
79
-
-
0028916513
-
Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions
-
M. Noris, M. Morigi, R. Donadelli, S. Aiello, M. Foppolo, M. Todeschini, S. Orisio, G. Remuzzi, and A. Remuzzi Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions Circ Res 76 1995 536 543
-
(1995)
Circ Res
, vol.76
, pp. 536-543
-
-
Noris, M.1
Morigi, M.2
Donadelli, R.3
Aiello, S.4
Foppolo, M.5
Todeschini, M.6
Orisio, S.7
Remuzzi, G.8
Remuzzi, A.9
-
80
-
-
85047675995
-
Nitric oxide release from porcine mitral valves
-
L. Siney, and M.J. Lewis Nitric oxide release from porcine mitral valves Cardiovasc Res 27 1993 1657 1661
-
(1993)
Cardiovasc Res
, vol.27
, pp. 1657-1661
-
-
Siney, L.1
Lewis, M.J.2
-
81
-
-
33947400181
-
Direct measurements of nitric oxide release in relation to expression of endothelial nitric oxide synthase in isolated porcine mitral valves
-
S.G. Moesgaard, L.H. Olsen, B. Aasted, B.M. Viuff, L.G. Pedersen, H.D. Pedersen, and A.P. Harrison Direct measurements of nitric oxide release in relation to expression of endothelial nitric oxide synthase in isolated porcine mitral valves J Vet Med A Physiol Pathol Clin Med 54 2007 156 160
-
(2007)
J Vet Med A Physiol Pathol Clin Med
, vol.54
, pp. 156-160
-
-
Moesgaard, S.G.1
Olsen, L.H.2
Aasted, B.3
Viuff, B.M.4
Pedersen, L.G.5
Pedersen, H.D.6
Harrison, A.P.7
-
82
-
-
33846906988
-
Increased nitric oxide release and expression of endothelial and inducible nitric oxide synthases in mildly changed porcine mitral valve leaflets
-
S.G. Moesgaard, L.H. Olsen, B.M. Viuff, U. Baandrup, L.G. Pedersen, P.D. Thomsen, H.D. Pedersen, and A.P. Harrison Increased nitric oxide release and expression of endothelial and inducible nitric oxide synthases in mildly changed porcine mitral valve leaflets J Heart Valve Dis 16 2007 67 75
-
(2007)
J Heart Valve Dis
, vol.16
, pp. 67-75
-
-
Moesgaard, S.G.1
Olsen, L.H.2
Viuff, B.M.3
Baandrup, U.4
Pedersen, L.G.5
Thomsen, P.D.6
Pedersen, H.D.7
Harrison, A.P.8
-
83
-
-
0041412645
-
Increased nadph-diaphorase activity in canine myxomatous mitral valve leaflets
-
L.H. Olsen, K. Mortensen, T. Martinussen, L.I. Larsson, U. Baandrup, and H.D. Pedersen Increased nadph-diaphorase activity in canine myxomatous mitral valve leaflets J Comp Pathol 129 2003 120 130
-
(2003)
J Comp Pathol
, vol.129
, pp. 120-130
-
-
Olsen, L.H.1
Mortensen, K.2
Martinussen, T.3
Larsson, L.I.4
Baandrup, U.5
Pedersen, H.D.6
-
84
-
-
0034120715
-
Mitogenic and secretory responses of human valve interstitial cells to vasoactive agents
-
S. Hafizi, P.M. Taylor, A.H. Chester, S.P. Allen, and M.H. Yacoub Mitogenic and secretory responses of human valve interstitial cells to vasoactive agents J Heart Valve Dis 9 2000 454 458
-
(2000)
J Heart Valve Dis
, vol.9
, pp. 454-458
-
-
Hafizi, S.1
Taylor, P.M.2
Chester, A.H.3
Allen, S.P.4
Yacoub, M.H.5
-
85
-
-
0032829324
-
Species differences in expression of angiotensin ii receptors and angiotensin-converting enzyme in human, canine and rat mitral valve leaflets
-
T. Mow, K. Poulsen, A.H. Nielsen, U. Baandrup, B.F. Hansen, and H.D. Pedersen Species differences in expression of angiotensin ii receptors and angiotensin-converting enzyme in human, canine and rat mitral valve leaflets Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 124 1999 11 17
-
(1999)
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol
, vol.124
, pp. 11-17
-
-
Mow, T.1
Poulsen, K.2
Nielsen, A.H.3
Baandrup, U.4
Hansen, B.F.5
Pedersen, H.D.6
-
86
-
-
0347172983
-
No expression of angiotensin ii receptors and angiotensin-converting enzyme in myxomatous canine mitral valve leaflets. An autoradiographic study
-
T. Mow, and H.D. Pedersen No expression of angiotensin ii receptors and angiotensin-converting enzyme in myxomatous canine mitral valve leaflets. An autoradiographic study Zentralbl Veterinarmed A 46 1999 465 472
-
(1999)
Zentralbl Veterinarmed A
, vol.46
, pp. 465-472
-
-
Mow, T.1
Pedersen, H.D.2
-
87
-
-
0034070354
-
Angiotensin ii directly increases transforming growth factor beta1 and osteopontin and indirectly affects collagen mrna expression in the human heart
-
C. Kupfahl, D. Pink, K. Friedrich, H.R. Zurbrugg, M. Neuss, C. Warnecke, J. Fielitz, K. Graf, E. Fleck, and V. Regitz-Zagrosek Angiotensin ii directly increases transforming growth factor beta1 and osteopontin and indirectly affects collagen mrna expression in the human heart Cardiovasc Res 46 2000 463 475
-
(2000)
Cardiovasc Res
, vol.46
, pp. 463-475
-
-
Kupfahl, C.1
Pink, D.2
Friedrich, K.3
Zurbrugg, H.R.4
Neuss, M.5
Warnecke, C.6
Fielitz, J.7
Graf, K.8
Fleck, E.9
Regitz-Zagrosek, V.10
|