Multi-component synthesis and in vitro and in vivo anticancer activity of novel arylmethylene bis-isoxazolo[4,5-b]pyridine-N-oxides

European Journal of Medicinal Chemistry

Volumn 50, Issue , 2012, Pages 274-279

  Rajanarendar, E ^a   Raju, S ^a   Reddy, M Nagi ^a   Krishna, S Rama ^a   Kiran, L Hari ^a   Narasimha Reddy, A Ram ^a   Reddy, Y Narasimha ^a  

^a KAKATIYA UNIVERSITY   (India)

Author keywords

In vitro anticancer activity; In vivo anticancer activity; Multi component synthesis; Novel arylmethylene bis isoxazolo 4,5 b pyridine N oxides

Indexed keywords

1,3 BIS(3 METHYL 4 NITROISOXAZOL 5 YL) 2 ARYLPROPANE DERIVATIVE; 3 METHYL 4 NITRO 5 STYRYLISOXAZOLE DERIVATIVE; 7,7' (2 CHLOROPHENYLMETHYLENE)BIS(3 METHYL 6 PHENYLISOXAZOLO[4,5-B]PYRIDINE N OXIDE); 7,7' (2 METHOXYPHENYLMETHYLENE)BIS(3 METHYL 6 PHENYLISOXAZOLO[4,5B]PYRIDINE N OXIDE); 7,7' (2 METHYLPHENYLMETHYLENE)BIS(3 METHYL 6 PHENYLIPHENYLISOXAZOLO[4,5-B]PYRIDINE N OXIDE); 7,7' (4 CHLOROPHENYLMETHYLENE)BIS(3 METHYL 6 PHENYLISOXAZOLO[4,5-B]PYRIDINE N OXIDE); 7,7' (PHENYLMETHYLENE)BIS(3 METHYL 6 PHENYLISOXAZOLO[4,5-B]PYRIDINE N OXIDE); 7,7' (PHENYLMETHYLENE)BIS[3 METHYL 6 (2 HYDROXYPHENYL)ISOXAZOLO[4,5-B]PYRIDINE N OXIDE]; 7,7' (PHENYLMETHYLENE)BIS[3 METHYL 6 (4 CHLOROPHENYL)ISOXAZOLO[4,5-B]PYRIDINE N OXIDE]; 7,7' (PHENYLMETHYLENE)BIS[3 METHYL 6 (4 METHOXYLPHENYL)ISOXAZOLO[4,5-B]PYRIDINE N OXIDE]; 7,7' (PHENYLMETHYLENE)BIS[3 METHYL 6 (4 METHYLPHENYL)ISOXAZOLO[4,5-B]PYRIDINE N OXIDE]; 7,7' (PHENYLMETHYLENE)BIS[3 METHYL 6 (4 NITROPHENYL)ISOXAZOLO[4,5-B]PYRIDINE N OXIDE]; ANTINEOPLASTIC AGENT; ARYLMETHYLENE BIS ISOXAZOLO[4,5-B]PYRIDINE N OXIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ONE POT SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; CYCLIC N-OXIDES; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; ISOXAZOLES; MICE; MOLECULAR STRUCTURE; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84858445099     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.02.004     Document Type: Article

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