Biosensor-controlled perfusion culture to estimate the viability of cells

Medical and Biological Engineering and Computing

Volumn 40, Issue 6, 2002, Pages 704-711

  von Woedtke, Thomas ^a,b   Julich W D ^a   Alhitari, N ^a   Hanschke, R ^a   Abel, P U ^a,b  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b Sensor Research Centre   (Germany)

Author keywords

Biosensor; Copper; Cytotoxicity; Glucose consumption; Hydrogen peroxide; Perfusion cell culture

Indexed keywords

BIOSENSORS; CELL CULTURE; ENZYMES; MONITORING;

CELL CULTIVATION;

CELLS;

GLUCOSE; HYDROGEN PEROXIDE;

ARTICLE; BIOLOGICAL MONITORING; CELL CULTURE; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; ENZYMIC BIOSENSOR; GLUCOSE INTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NON INVASIVE MEASUREMENT; NUTRIENT; PERFUSION; CELL SURVIVAL; CULTURE TECHNIQUE; DRUG EFFECT; GENETIC PROCEDURES; METABOLISM; METHODOLOGY;

BIOSENSING TECHNIQUES; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CULTURE MEDIA; GLUCOSE; HUMANS; HYDROGEN PEROXIDE;

EID: 1842845088     PISSN: 01400118     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02345309     Document Type: Article

References (37)

1. ABEL, P., WILKE, W., HÜBNER, G., and KRÜGER, I. (1983): Kontinuierliche Bestimmung der Blutglukose mittels Enzymelektrode', Z. med. Labor-Diagn., 24, pp. 264-270
2. ABEL, P., MÜLLER, A., and FISCHER, U. (1984): 'Experience with an implantable glucose sensor as a prerequisite of an artificial beta cell', Biomed. Biochim. Acta, 43, pp. 577-584
3. ABEL, P., VON WOEDTKE, TH., REBRIN, K., SCHLOSSER, M., and FISCHER, U. (1993): 'Glucose biosensor for in vivo application' in ALCOCK, S. J., and TURNER, A. P. F. (Eds): 'In vivo chemical sensors. Recent development' (Cranfield, 1993), pp. 16- 26
4. ABEL, P. U., VON WOEDTKE, TH., SCHULZ, B., BERGANN, TH., and SCHWOCK, A. (1999): 'Stability of immobilized enzymes as biosensors for continuous application in vitro and in vivo', J. Mol. Cat. B: Enzymatic, 7, pp. 93-100
5. ADRIAN, V., JÜLICH, W.-D., ALHITARI, N., VON WOEDTKE, TH., and ABEL, P. (1998): 'Einfluß von antimikrobiell wirksamen Einschlussverbindungen des Wasserstoffperoxids auf humane Amnionepithelzellen', Hyg. Med., 23, p. 94
6. AWADH ALI, N. A., JÜLICH, W.-D., KUSNICK, C., and LINDEQUIST, U. (2001): 'Screening of Yemeni medicinal plants for antibacterial cytotoxic activities', J. Ethnopharmacol., 74, pp. 173-179
7. CARTWRIGHT, T., and SHAH, G. P. (1994): 'Culture media' in DAVIS, J. M. (Ed.): 'Basic cell culture. A practical approach' (IRL Press at Oxford University Press, Oxford, New York, Tokyo, 1994), pp. 57-91
8. EHRET, R., BAUMANN, W., BRISCHWEIN, M., SCHWINDE, A., STEGBAUER, K., and WOLF, B. (1997): 'Monitoring of cellular behaviour by impedance measurements on interdigitated electrode structures', Biosens. Bioelectron., 12, pp. 29-41
9. EL-HAG, A., and CLARK, R. A. (1984): 'Down regulation of human natural killer activity against tumors by the neutrophil myeloperoxidase system and hydrogen peroxide', J. Immunol., 133, pp. 391-397
10. FENSKE, CH., GÜNTHER, B., KNAUER, A., RUDOLPH, P., ADRIAN, V., VON WOEDTKE, TH., ROSSBERG, H., KRAMER, A., and JÜLICH, W.-D. 'Comparison of different biological methods for the assessment of toxicological risks', Acta hydrobiol. hydrochim. (in press)
11. FEWTRELL, L., KAY, D., and MACGILL, S. (2001): 'A review of the science behind drinking water standards for copper', Int. J. Environ. Health Res., 11, pp. 161-167
12. FISCHER, U., REBRIN, K., VON WOEDTKE, TH., and ABEL, P. (1994): 'Clinical usefulness of the glucose concentration in the subcutaneous tissue-properties and pitfalls of electrochemical biosensors', Horm. Metab. Res., 26, pp. 515-522
13. FLEMMING, CH., GABERT, A., and ROTH, P. (1974): 'Synthese und Eigenschaften trägerfixierter Enzyme. VI. Kovalente Bindung von Glucoseoxidase an Dialdehydepidex und Dialdehydzellulose', Acta Biol. Med. Germ., 33, pp. 15-20
14. GEORGOPOULOS, P. G., ROY, A., YONONE-LIOY, M. J., OPIEKUN, R. E., and LIOY, P. J. (2001): 'Environmental copper: its dynamics and human exposure issues', J. Toxicol. Environ. Health B Crit. Rev., 4, pp. 341-394
15. GIAEVER, I., and KEESE, CH. R. (1993): 'A morphological biosensor for mammalian cells', Nature, 366, pp. 591-592
16. HANSCHKE, R., and JÜLICH, W.-D. (2000): Patent application DE 19851776 A 1, 11.05.2000
17. JÜLICH, W.-D., HANSCHKE, R., and ALHITARI, N. (1998): 'Gentle sterilisation of biologically active implants. Part IV: Comparative electron microscope observations on the influence of hydrogen peroxide and hydrogen peroxide/surfactant urea inclusion compounds on human amnion epithelial cells in a perfusion cell culture', Hyg. Med., 23, pp. 465-472
18. JÜLICH, W.-D., OHME, R., ALHITARI, N., ADRIAN, V., VON WOEDTKE, TH., and KRAMER, A. (1999): 'Synthesis, antimicrobial efficacy, and tolerability of new structures of urea, hydrogen peroxide and tensides' Pharmazie, 54, pp. 171-178
19. KEESE, CH. R., and GIAEVER, I. (1994): 'A biosensor that monitors cell morphology with electrical fields', IEEE Eng. Med. Biol., June/July, pp. 401-408
20. KLOTH, S., and SUTER-CRAZZOLARAR, C. (2000): 'Modulation of rebal blood vessel formation by glial cell line-derived neurotropic factor', Microvascular Research, 59, pp. 190-194
21. KRAMER, A., HALLE, W., WEUFFEN, W., ADRIAN, V., HERRMANN, M., BREMER, J., FLECK, H., and STEIGER, E. (1987): 'Microbiostatic effectivity, cytotoxicity and phytotoxicity as a basic information for the compatibility of antimicrobial agents', Z. gesamte Hyg., 33, pp. 610-615
22. KRAMER, A., ADRIAN, V., and ADAM, CH. (1993): 'Comparison of the toxicity of Lavasept® and selected antiseptic agents', Hyg. Med., 18, pp. 9-16
23. KRAMER, A., JÜLICH, W.-D., and OHME, R. (1995): 'New functional supramolecular structures of urea, hydrogen peroxide and tensides suitable for use as preservatives. First communication: Working hypothesis, bacteriostatic efficacy and skin tolerability', Hyg. Med., 20, pp. 330-343
24. KREKLAU, B., SITTINGER, M., MENSING, M. B., VOIGT, C., BERGER, G., BURMESTER, G. R., RAMANZADEH, R., and GROSS, U. (1999): 'Tissue engineering of biphasic joint cartilage transplants', Biomaterials, 20, pp. 1743-1749
25. LEHMANN, M., BAUMANN, W., BRISCHWEIN, M., EHRET, R., KRAUS, M., SCHWINDE, A., BITZENHOFER, M., FREUND, I., and WOLF, B. (2000): 'Non-invasive measurement of cell membrane associated proton gradients by ion-sensitive field effect transistor arrays for microphysiological and bioelectronical applications', Biosens. Bioelectron., 15, pp. 117-124
26. LEHMANN, M., BAUMANN, W., BRISCHWEIN, M., GAHLE, H.-J., FREUND, I., EHRET, R., DRECHSLER, S., PALZER, H., KLEINTGES, M., SIEBEN, U., and WOLF, B. (2001): 'Simultaneous measurement of cellular respiration and acidification with a single CMOS ISFET', Biosens. Bioelectron., 16, pp. 195-203
27. MCATEER, J. A., and DAVIES, J. (1994): 'Basic cell culture technique and the maintenance of cell lines' in DAVIS, J. M. (Ed.): 'Basic cell culture. A practical approach' (IRL Press at Oxford University Press, Oxford, New York, Tokyo), pp. 93-148
28. MCCONNELL, H. M., OWICKI, J. C., PARCE, J. W., MILLER, D. L., BAXTER, G. T., WADA, H. G., and PITCHFORD, S. (1992): 'The Cytosensor Microphysiometer: Biological applications of silicon technology', Science, 257, pp. 1906-1912
29. MINUTH, W. W., STÖCKL, G., KLOTH, S., and DERMIETZEL, R. (1992): 'Construction of an apparatus for perfusion cell cultures which enables in vitro experiments under organotypic conditions', Eur. J. Cell Biol., 57, pp. 132-137
30. MINUTH W. W., KLOTH, S., AIGNER, J., SITTINGER, M., and RÖCKL, W. (1996): 'Approach to an organo-typical environment for cultured cells and tissues', BioTechniques, 20, pp. 498-501
31. MINUTH, W. W., SCHUMACHER, K., STREHL, R., and KLOTH, S. (2000): 'Physiological and cell biological aspects of perfusion culture technique employed to generate differentiated tissues for long term biomaterial testing and tissue engineering', J. Biomater. Sci. Polymer Edn., 5, pp. 495-522
32. SITTINGER, M., SCHULTZ, O., KEYSZER, G., MINUTH, W. W., and BURMESTER, G. R. (1997): 'Artificial tissues in perfusion culture', Int. J. Artif. Organs, 20, pp. 57-62
33. TEMENOFF, J. S., and MIKOS, A. G. (2000): 'Review: tissue engineering for regeneration of articular cartilage', Biomaterials, 21, pp. 431-440
34. VON WOEDTKE, TH., LINDEQUIST, U., ALHITARI, N., KUSNICK, C., JÜLICH, W.-D., and ABEL, P. U. (2002a): 'The usefulness of a biosensor controlled perfusion cell culture for the investigation of new drugs demonstrated with the marine fungus Kirschsteiniothelia maritima', Pharmazie, 57, pp. 270-274
35. VON WOEDTKE, TH., JÜLICH, W.-D., HARTMANN, V., STIEBER, M., and ABEL, P. U. (2002b): 'Sterilization of enzyme glucose sensors: problems and concepts', Biosens. Bioelectron., 17, pp. 373-382
36. WEETALL, H. (1970): 'Storage stability of water insoluble enzymes covalently coupled to organic and anorganic carriers', Biochem. Biophys. Acta, 212, pp. 1-7
37. WOLF. B., BRISCHWEIN, M., BAUMANN, W., EHRET, R., and KRAUS, M. (1998): 'Monitoring of cellular signalling and metabolism with modular sensor-technique: The PhysioControl-Microsystem (PCM®)', Biosens. Bioelectron., 13, pp. 501-509