Concurrent T cell leukaemia and equine multinodular pulmonary fibrosis in a Hanoverian Warmblood mare

Equine Veterinary Education

Volumn 24, Issue 4, 2012, Pages 187-192

  Schwarz, B ^a   Gruber, A ^a   Benetka, V ^a   Rutgen B ^a   Schwendenwein, I ^a   Leidinger, E ^b   van den Hoven, R ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b INVITRO   (Austria)

Author keywords

herpesvirus; EMPF; Horse; Immunosuppression; Leukaemia

Indexed keywords

EQUID HERPESVIRUS 5; EQUIDAE; HERPESVIRIDAE; HUMAN HERPESVIRUS 4;

EID: 84858335320     PISSN: 09577734     EISSN: 20423292     Source Type: Journal    
DOI: 10.1111/j.2042-3292.2011.00257.x     Document Type: Article

References (21)

1. Dascanio, J.J., Zhang, C.H., Antczak, D.F., Blue, J.T. and Simmons, T.R. (1992) Differentiation of chronic lymphocytic leukaemia in the horse: a report of two cases. J. vet. intern. Med. 6, 225-229.
2. Doran, P. and Egan, J.J. (2005) Herpesviruses: a cofactor in the pathogenesis of idiopathic pulmonary fibrosis? Am. J. Physiol. Lung Cell. Mol. Physiol. 289, 709-710.
3. Fortier, G., Van Erck, E., Pronost, S., Lekeux, P. and Thiry, E. (2010) Equine gammaherpesviruses: pathogenesis, epidemiology and diagnosis. Vet. J. 186, 148-156.
4. Hart, K.A., Barton, M.H., Williams, K.J., Flaminio, M.J.B. and Howerth, E.W. (2008) Multinodular pulmonary fibrosis, pancytopenia and equine herpesvirus-5 infection in a Thoroughbred gelding. Equine vet. Educ. 20, 470-476.
5. Kawa, K. (2000) Epstein-Barr virus associated diseases in humans. Int. J. Hematol. 71, 108-117.
6. Lester, G.D., Alleman, A.R., Raskin, R.E. and Meyer, J.C. (1993) Pancytopenia secondary to lymphoid leukemia in three horses. J. vet. intern. Med. 7, 360-363.
7. Lunn, P. and Horohov, D. (2010) The equine immune system. In: Equine Internal Medicine, 3rd edn., Eds: S.M. Reed, W.M. Bayly and D.C. Sellon, Saunders Elsevier, St. Louis, USA. pp 2-56.
8. Mair, T.S. and Couto, C.G. (2006) The use of cytotoxic drugs in equine practice. Equine vet. J. 18, 149-156.
9. Mayr, A. and Kaaden, O.R. (2006) Viruserkrankungen der Tiere. In: Medizinische Mikrobiologie, Infektions- und Seuchenlehre, 8th edn., Eds: M. Rolle and A. Mayr, Enke Verlag, Stuttgart, Germany. pp 136-343.
10. McClure, J.T., Young, K.M., Fistle, M., Sharkey, L.C. and Lunn, D.P. (2001) Immunphenotypic classification of leukaemia in 3 horses. J. vet. intern. Med. 15, 144-152.
11. Munoz, A., Riber, C., Trigo, P. and Castejon, F. (2009) Hematopoietic neoplasias in horses: Myeloproliferative and lymphoproliferatie disorders. J. Equine Sci. 20, 59-72.
12. Niedermayer, G., Poth, T. and Gehlen, H. (2010) Clinical aspects of multinodular pulmonary fibrosis in two warmblood horses. Vet. Rec. 166, 426-430.
13. Poth, T., Niedermayer, G. and Hermanns, W. (2009) Equine multinodular pulmonary fibrosis in association with an EHV-5 infection in 5 horses. Wien. Tierärztl. Mschr. 96, 203-208.
14. Rendle, D.I., Durham, A.E., Thompson, J.C., Archer, J., Mitchell, M., Saunders, K., Millere, J., Paillot, R., Smith, K.C. and Kydd, J.H. (2007) Clinical, immunophenotypic and functional characterisation of T-cell leukaemia in six horses. Equine vet. J. 39, 522-528.
15. Sellon, D.C. and Wise, L.N. (2010) Disorders of the hematopoietic system. In: Equine Internal Medicine, 3rd edn., Eds: S.M. Reed, W.M. Bayly and D.C. Sellon, Saunders Elsevier, St. Louis, USA. pp 730-776.
16. Torfason, E.G., Thorsteinsdottir, L., Torsteindottir, S. and Scansson, V. (2008) Study ofequid herpesvirus 2 an 5 in Iceland with a type-specific polymerase chain reaction. Res. vet. Sci. 85, 605-611.
17. VanDevanter, D.R., Warrener, P., Bennett, L., Schultz, E.R., Coulter, S., Garber, R.L. and Rose, T.M. (1996) Detection and analysis of diverse Herpesviral species by consensus primer PCR. J. clin. Microbiol. 34, 1666-1671.
18. Vanella, K.M. and Moore, B.B. (2008) Viruses as co-factors for the initiation or exacerbation of lung fibrosis. Fibrogenesis Tissue Repair 1, 2.
19. Wilkins, P.A. (2008) Equine multinodular pulmonary fibrosis: New, emerging or simply recently described? Equine vet. Educ. 20, 477-479.
20. Williams, K.J., Maes, R., Del Piero, F., Lim, A., Wise, A., Bolin, D.C., Caswell, J., Jackson, C., Robinson, N.E., Derksen, F., Scott, M.A., Uhal, B.D., Li, C., Youseef, S.A. and Bolin, S.R. (2007) Equine multinodular pulmonary fibrosis: a newly recognised herpesvirus-associated fibrotic lung disease. Vet. Pathol. 44, 849-862.
21. Wong, D.M., Belgrave, R.L., Williams, K.J., Del Piero, F., Alcott, C.J., Bolin, S.R., Marr, C.M., Nolen-Walston, R., Myers, R.K. and Wilkins, P.A. (2008) Multinodular pulmonary fibrosis in five horses. J. Am. vet. med. Ass. 232, 898-905.