Hematopoietic neoplasias in horses: Myeloproliferative and lymphoproliferative disorders

Journal of Equine Science

Volumn 20, Issue 4, 2010, Pages 59-72

  Muñoz, Ana ^a   Riber, Cristina ^a   Trigo, Pablo ^a   Castejón, Francisco ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Anemia; Blood; Clinical pathology; Horses; Leukemia

Indexed keywords

EQUIDAE;

EID: 75849151689     PISSN: 13403516     EISSN: 13477501     Source Type: Journal    
DOI: 10.1294/jes.20.59     Document Type: Article

References (70)

1. Angel, K.L., Spano, J.S., Schumacher, J., and Kwapien, R.P. 1991. Myelophthisic pancytopenia in a pony mare. J. Am. Vet. Med. Assoc. 198: 1039-1042.
2. Barton, M.H., Sharma, P., LeRoy, B.E., and Howerth, E.W. 2004. Hypercalcemia and high serum parathyroid hormone-related protein concentration in a horse with multiple myeloma. J. Am. Vet. Med. Assoc. 3: 409-413.
3. Beech, J., Bloom, J.C., and Hodge, T.G. 1984. Erythrocytosis in a horse. J. Am. Vet. Med. Assoc. 184: 986-989.
4. Bernard, W.W., Sweeney, C.R., and Morris, F. 1988. Primary lymphocyte leukemia in a horse. Equine Pract. 10: 24-30.
5. Bienzle, D., Hudgson, S.L., and Vernau, W. 1993. Acute myelomonocytic leukemia in a horse. Can. Vet. J. 34: 36-37.
6. Blue, J., Perdizet, J., and Brown E. 1987. Pulmonary aspergi llosis in a horse with myelomonocytic leukemia. J. Am. Vet. Med. Assoc. 190: 1562-1564.
7. Boudreaux, M.K., Blue, I.T., Durham, S.K., and Vivrette, S.L. 1984. Intravascular leukostasis in a horse with myelomonocytic leukemia. Vet. Pathol. 21: 544-546.
8. Brown, D.E., Thrall, M.A., Getzy, D.M., Weiser, M.G., and Ogilvie, G.K. 1994. Cytology of canine malignant histiocytosis. Vet. Clin. Pathol. 23: 118-123.
9. Brumbaugh, G.W., Stitzel, K.A., Zinkl, J.G., and Feldman, B.F. 1982. Myelomonocyt ic myeloproliferative disease in a horse. J. Am. Vet. Med. Assoc. 180: 313-316.
10. Buechner-Maxwell, V., Zhang, C., Robertson, J., Jain, N.C., Antczak, D.F., Feldman, B.F., and Murray, M.J. 1994. Intravascular leukostasis and systemic aspergillosis in a horse with subleukemic acute myelomonocytic leukemia. J. Vet. Intern. Med. 8: 258-263.
11. Chaffin, M.K., Schmitz, D.G., Brumbaugh, G.W., and Hall, D.G. 1992. Ultrasonographic charact e r i s t i cs of splenic and hepatic lymphosarcoma in three horses. J. Am. Vet. Med. Assoc. 201: 743-747.
12. Chen, Y-H., and Magalhaes, M.C. 1990. Hypoalbuminemia in patients with multiple myeloma. Arch. Intern. Med. 150: 605-610.
13. Cortese, L., Paciello, O., and Papparella, S. 2008. Morphological characterization of malignant histiocytosis in a cat. Folia Morphol (Warsz) 67: 299-303.
14. Court, E.A., Earnest-Koons, K.A., Barr, S.C., and Gould, W.J. 2nd. 1993. Malignant histiocytosis in a cat. J. Am. Vet. Med. Assoc. 203: 1300-1302.
15. Dascanio, J.J., Zhang, C.H., Antczak, D.F., Blue, J.T., and Simmons, T.R. 1992. Differentiation of chronic lymphocytic leukemia in the horse: a report of two cases. J. Vet. Intern. Med. 6: 225-229.
16. De Bruin, C.M., Veenman, J.N., Rutten, V.P.M.G., Teske, E., Van Nieuwstadt, R.A., and Van den Ingh, T.S.G.A.M. 2007. Clinical, histopathological and immunophenotypical findings in five horses with cutaneous malignant lymphoma. Res. Vet. Sci. 83: 63-72.
17. De Clercq, D., Van Loon, G., Lefére, L., and Deprez, P. 2004. Ultrasound-guided biopsy as adiagnostic aid in three horses with a cranial mediastinal lymphosarcoma. Vet. Rec. 154: 722-726.
18. Edwards, D.F., Parker, J.W., Wilkinson, J.E., and Helman, R.G. 1993. Plasma cell myeloma in the horse. A case report and literature review. J. Am. Vet. Med. Assoc. 7: 169-176.
19. Fox, A., and Miller, L. 1987. Equine adrenocortical carcinoma with hypercalcemia. Vet. Pathol. 24: 190-192.
20. Fulmer, A.K., and Mauldin, G.K. 2007. Canine histiocytic neoplasia: an overview. Can. Vet. J. 48: 1041-1050.
21. Geelen, S.N., Bernadina, W.E., Grinwis, G.C., and Kalsbeek, H.C. 1997. Monoclonal gammopathy in a Dutch warmblood mare. Vet. Quaterly 19: 29-32.
22. Gerard, M.P., Healy, L.N., Bowman, K.F., and Miller, R.T. 1998. Cutaneous lymphoma with extensive periarticular involvement in a horse. J. Am. Vet. Med. Assoc. 213: 391-393.
23. Grogan, T.M., Van Camp, B., Kyle, R.A., Müller-Hermelink, H.K., and Harrs, N.L. 2001. Plasma cell neoplasms. pp.142-148. In: World Health Organization. Classifications of tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid tissues (Jafle, E.S., Harris, N.L., Stein, H., Vardman, J.W. eds.), IARC Press, Lyon.
24. Hayle, P.T., and Spraker, T. 1983. Lymphosarcoma in an aborted equine fetus. Vet. Pathol. 20: 647-649.
25. Henry, M., Prasse, K., and White, S. 1989. Hemorrhagic diathesis caused by multiple myeloma in a three-month old foal. J. Am. Vet. Med. Assoc. 194: 392-394.
26. Herraez, P., Berridge, B., Marsh, P., Weeks, B., and Ramiro-Ibañez, F. 2001. Small intestine large granular lymphoma in a horse. Vet. Pathol. 38: 223-226.
27. Jacobson, D.R., and Zolla-Pazner, S. 1986. Immunosuppression and infection in multiple myeloma. Semin. Oncol. 13: 282-290.
28. Jaffe, E.S., Harris, N.L., and Stein, H. 2001. World Health Organization Classification of Tumours: Pathology and Genetics of Tumors of Haematopoietic and Lymphoid Tissues. pp.20-28. IARC Press, Lyon.
29. Johansson, A.M., Skidell, J., Lilliehöök, I., and Tvedten, H.W. 2007. Chronic granulocytic leukemia in a horse. J. Vet. Intern. Med. 21: 1126-1129.
30. Kannegieter, N.J., and Alley, M.R. 1987. Ataxia due to lymphosarcoma in a young horse. Aust. Vet. J. 64: 377-379.
31. Karadia, S.B. 1980. Multiple myeloma: a clinicopathologic study of 62 consecutively autopsied cases. Medicine 59: 380-392.
32. Kelton, D.R., Holbrook, T.C., Gilliam, L.L., Rizzi, T.E., Brosnaham, M.M., and Confer, A.W. 2008. Bone marrow necrosis and myelophthisis: manifestations of T-cell lymphoma in a horse. Vet. Clin. Pathol. 37: 403-408.
33. Kent, J.E., and Roberts, C.A. 1990. Serum protein changes in four horses with monoclonal gammopathy. Equine Vet. J. 22: 373-376.
34. Kim, D.M., Taylor, H.W., Eades, S.C., and Cho, D.Y. 2005. Systemic AL amyloidosis associated with multiple myeloma in a horse. Vet. Pathol. 42: 81-84.
35. Knottenbelt, D.C. 2003. Internal neoplasia: lymphosarcoma and myeloproliferative disease. In: 9° Congressso Nazionale Multisala SIVE, Italy
36. Kohn, C.W., Swardson, C., Provost, P., Gilbert, R.O., and Couto, C.G. 1995. Myeloid and megakaryocyt ic hypoplasia in related Standardbreds. J. Vet. Intern. Med. 9: 315-323.
37. Kyle, R.A. 1975. Multiple myeloma: review of 869 cases. Mayo Clin. Proc. 50: 29-40.
38. Kyle, R.A., and Greipp, P.R. 1978. The laboratory investigation of monoclonal gammopathies. Mayo Clin. Proc. 53: 719-739.
39. Lester, G.D., Alleman, A.R., Raskin, R.E., and Mays, M.B. 1993. Malignant histiocytosis in an Arabian filly. Equine Vet. J. 25: 471-473.
40. Lester, G.D., Alleman, A.R., Raskin, R.E., and Meyer, J.C. 1993. Pancytopenia secondary to lymphoid leukemia in three horses. J. Vet. Intern. Med. 7: 360-363.
41. Lewis, H.B., and Leitch, A. 1975. A case of granulocytic leukemia in the horse. pp. 141-143. In: Equine Hematology Proceedings of the American Association of Equine Practitioners, Boston.
42. Mair, T.S., Pearson, G.R., and Divers, T.J. 2007. Malabsorption syndromes in the horse. Equine Vet. Educ. 18: 299-308.
43. Mair, T.S., Yeo, S.P., and Lucke, V.M. 1990. Hypercalcaemia and soft tissue mineralization associated with lymphosarcoma in two horses. Vet. Rec. 126: 99-101.
44. Markel, D.D., and Dorr, T.E. 1986. Multiple myeloma in a horse. J. Am. Vet. Med. Assoc. 188: 621-624
45. McConkey, S., Lopez, A., and Pringle, J. 2000. Extramedullary plasmocytoma in a dog with ptyalism and dysphagia. J. Vet. Diagn. Invest. 12:282-284
46. McFarlane, D., Sellon, D.C., and Parker, B. 1998. Primary erythrocytosis in a 2-year-old Arabian gelding. J. Vet. Intern. Med. 12: 384-388.
47. Meyer, J., DeLay, J., and Bienzle, D. 2006. Clinical, laboratory, and histopathologic features of equine lymphoma. Vet. Pathol. 43: 914-924.
48. Miseta, A., Kellermayer, M., Kollar, B., and Bogner, R. 1989. Paraproteins associated with low plasma sodium levels. Physiol. Chem. Phys. Med. NMR 21: 171-175.
49. Morris, D.D., Bloom, J., Roby, K.A., Woods, K., and Tablin, F. 1984. Eosinophilic myeloproliferative disorder in a horse. J. Am. Vet. Med. Assoc. 185: 993-996.
50. Morrison, L.R., Freel, K., Henderson, I., Hahn, C., and Smith, S.H. 2008. Lymphoproliferative disease with features of lymphoma in the central nervous system of a horse. J. Comp. Pathol. 139: 256-261.
51. Oken, M.M. 1984. Multiple myeloma. Med. Clin. North Am. 68: 757-787.
52. Perkins, G.A., Nydam, D.V., Flaminio, M.J., and Ainsworth D.M. 2003. Serum IgM concentrations in normal, fit horses and horses with lymphoma or other medical conditions. J. Vet. Intern. Med. 17: 337-342.
53. Perkins, H.A., MacKenzie, M.R., and Rudenberg, H.H. 1970. Hemostatic defects in dysproteinemias. Blood 35: 695-707.
54. Polkes, A.C., Alleman, A.R., Lester, G.D., Beurgelt, C.D., and McSherry, L.J. 1999. B-cell lymphoma in a horse with associated Sézary-like cells in the peripheral blood. J. Vet. Intern. Med. 13: 620-624.
55. Pusterla, N., Stacy, B.A., Vernau, W., De Cock, H.E.V., and Magdesian, K.G. 2004. Immunoglobulin A monoclonal gammopathy in two horses with multiple myeloma. Vet. Rec. 155: 19-23.
56. Raskin, R.E., and Krehbiel, J.D. 1988. Histopathology of canine bone marrow in malignant lymphoproliferative disorders. Vet. Pathol. 25: 83-88.
57. Rawstron, A.C., Bennett, F.L., O'Connor, S.J., Kwok, M., Fenton, J.A., Plummer, M., De Tute, R., Owen, R.G., Richards, S.J., Jack, A.S., and Hillmen, P. 2008. Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia. N. Engl. J. Med. 359: 575-583.
58. Rendle, D.I., Durham, A.E., Thompson, J.C., Archer, J., Mitchell, M., Saunders, K., Milliere, J., Paillot, R., Smith, K.C., and Kydd, J.H. 2007. Clinical, immunophenotypic and functional characterization of T-cell leukaemia in six horses. Equine Vet. J. 39: 522-528.
59. Rhind, S.M., and Dixon, P.M. 1999. T-cell rich B cell lymphosarcoma in the tongue of a horse. Vet. Rec. 145: 554-555.
60. Ringger, N.C., Edens, L., Bain, P., Raskin, R.E., and Larock, R. 1997. Acute myelogenous leukaemia in a mare. Aust. Vet. J. 75: 329-331.
61. Roccabianca, P., Paltrinieri, S., Gallo, E., and Giuliani, A. 2002. Hepatosplenic T-cell lymphoma in a mare. Vet. Pathol. 39: 508-511.
62. Sanchez-Avalos, J., Soong, B.C.F., and Miller, S.P. 1969. Coagulation disorders in cancer. II. Multiple Myeloma. Cancer 23: 1388-1398.
63. Savage, C.J. 1998. Lymphoproliferative and myeloproliferative disorders. Vet. Clin. North Am. Equine Pract. 14: 563-577.
64. Searcy, G.P., and Orr, J.P. 1981. Chronic granulocytic leukemia in a horse. Can. Vet. J. 22: 148-151.
65. Silberstein, L., Duggan, D., and Berkman, E. 1985. Therapeutic trial of plasma exchange in osteosclerotic myeloma associated with the POEMS syndrome. J. Clin. Apher. 2: 253-257.
66. Spiers, S.J., Madewell, B.R., Zinkl, J.E., and Ryan, A.M. 1986. Acute myelomonocytic leukemia in a horse. J. Am. Vet. Med. Assoc. 188: 861-863.
67. Sugiyama, A., Takeuchi, T., Morita, T., Matsuura, A., Kanda, T., Shimada, A., Amaya, T., and Hikasa, Y. 2008. Mediastinal lymphoma with complete atrioventricular block in a horse. J. Vet. Med. Sci. 70: 1101-1105.
68. Sweeney, R.W., Hamir, A.N., and Fisher, R.R. 1991. Lymphosarcoma with urinary bladder infiltration in a horse. J. Am. Vet. Med. Assoc. 199: 1177-1178.
69. Traub-Dargatz, J., Bertone, A., Bennett, D., Jones, R.L., Weingand, K., Hall, R., DeMartini, J.C., Lavach, J.D., and Roberts, S.M. 1985. Monoclonal aggregating immunoglobulin cryoglobulinemia in a horse with malignant lymphoma. Equine Vet. J. 17: 470-473.
70. Vasilopulos, R.J., and Mackin, A. 2003. Humoral hypercalcemia of malignancy: diagnosis and treatment. Compend. Contin. Educ. Pract. Vet. 25: 129-136