Equine multinodular pulmonary fibrosis: A newly recognized herpesvirus-associated fibrotic lung disease

Veterinary Pathology

Volumn 44, Issue 6, 2007, Pages 849-862

  Williams, Kurt J ^a   Maes, R ^a   Del Piero, F ^b   Lim, A ^a   Wise, A ^a   Bolin, D C ^c   Caswell, J ^d   Jackson, C ^e   Robinson, N E ^a   Derksen, F ^a   Scott, M A ^a   Uhal, B D ^f   Li, X ^f   Youssef, S A ^g   Bolin, S R ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Livestock Disease Diagnostic Center   (United States)

^d UNIVERSITY OF GUELPH   (Canada)

^e Equine Specialty Hospital   (United States)

^f MICHIGAN STATE UNIVERSITY   (United States)

^g UNIVERSITY OF GUELPH   (Canada)

Author keywords

Equine herpesvirus 5; Gamma herpesvirus; Horses; Lung; Pulmonary fibrosis

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; FEMALE; HERPES VIRUS INFECTION; HORSE; HORSE DISEASE; IMMUNOHISTOCHEMISTRY; ISOLATION AND PURIFICATION; LUNG; LUNG FIBROSIS; MALE; PATHOLOGY; POLYMERASE CHAIN REACTION; ULTRASTRUCTURE; VARICELLA ZOSTER VIRUS; VIROLOGY;

ANIMALS; FEMALE; HERPESVIRIDAE INFECTIONS; HORSE DISEASES; HORSES; IMMUNOHISTOCHEMISTRY; LUNG; MALE; POLYMERASE CHAIN REACTION; PULMONARY FIBROSIS; VARICELLOVIRUS;

ANIMALIA; EQUID HERPESVIRUS 2; EQUID HERPESVIRUS 5; EQUIDAE; HERPESVIRIDAE;

EID: 37149032735     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1354/vp.44-6-849     Document Type: Article

References (36)

1. Agius CT, Nagesha HS, Studdert MJ: Equine herpesvirus 5: comparisons with EHV2 (equine cytomegalovirus), cloning, and mapping of a new equine herpesvirus with a novel genome structure. Virology 191:176-186, 1992
2. Agius CT, Studdert MJ: Equine herpesviruses 2 and 5: comparisons with other members of the subfamily gammaherpesvirinae. Adv Virus Res 44:357-379, 1994
3. Bell SA, Balasuriya UB, Nordhausen RW, MacLachlan NJ: Isolation of equine herpesvirus-5 from blood mononuclear cells of a gelding. J Vet Diagn Invest 18:472-475, 2006
4. Brody JR, Kern SE: Sodium boric acid: a Tris-free, cooler conductive medium for DNA electrophoresis. Biotechniques 36:214-216, 2004
5. Browning GF, Studdert MJ: Genomic heterogeneity of equine betaherpesviruses. J Gen Virol 68:1441-1447, 1987
6. Buergelt CD, Hines SA, Cantor G, Stirk A, Wilson JH: A retrospective study of proliferative interstitial lung disease of horses in Florida. Vet Pathol 23:750-756, 1986
7. Craig MI, Barrandeguy ME, Fernandez FM: Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina. BMC Vet Res 1:9, 2005
8. Donaldson MT, Beech J, Ennulat D, Hamir AN: Interstitial pneumonia and pulmonary fibrosis in a horse. Equine Vet J 30:173-175, 1998
9. Doran P, Egan JJ: Herpesviruses: a cofactor in the pathogenesis of idiopathic pulmonary fibrosis? Am J Physiol Lung Cell Mol Physiol 289:L709-L710, 2005
10. Ebrahimi B, Dutia BM, Brownstein DG, Nash AA: Murine gammaherpesvirus-68 infection causes multi-organ fibrosis and alters leukocyte trafficking in interferon-gamma receptor knockout mice. Am J Pathol 158:2117-2125, 2001
11. Elia G, Decaro N, Martella V, Campolo M, Desario C, Lorusso E, Cirone F, Buonavoglia C: Detection of equine herpesvirus type 1 by real time PCR. J Virol Methods 133:70-75, 2006
12. Kelly BG, Lok SS, Hasleton PS, Egan JJ, Stewart JP: A rearranged form of Epstein-Barr virus DNA is associated with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 166:510-513, 2002
13. Kleiboeker SB, Schommer SK, Johnson PJ, Ehlers B, Turnquist SE, Boucher M, Kreeger JM: Association of two newly recognized herpesviruses with interstitial pneumonia in donkeys (Equus asinus). J Vet Diagn Invest 14:273-280, 2002
14. Lipscomb TP, Scott DP, Garber RL, Krafft AE, Tsai MM, Lichy JH, Taubenberger JK, Schulman FY, Gulland FM: Common metastatic carcinoma of California sea lions (Zalophus californianus): evidence of genital origin and association with novel gammaherpesvirus. Vet Pathol 37:609-617, 2000
15. Lok SS, Egan JJ: Viruses and idiopathic pulmonary fibrosis. Monaldi Arch Chest Dis 55:146-150, 2000
16. Lok SS, Haider Y, Howell D, Stewart JP, Hasleton PS, Egan JJ: Murine gammaherpes virus as a cofactor in the development of pulmonary fibrosis in bleomycin resistant mice. Eur Respir J 20:1228-1232, 2002
17. Mettenleiter TC: Budding events in herpesvirus morphogenesis. Virus Res 106:167-180, 2004
18. Mora AL, Woods CR, Garcia A, Xu J, Rojas M, Speck SH, Roman J, Brigham KL, Stecenko AA: Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice. Am J Physiol Lung Cell Mol Physiol 289:L711-L721, 2005
19. Nicholas J: Human gammaherpesvirus cytokines and chemokine receptors. J Interferon Cytokine Res 25: 373-383, 2005
20. Nordengrahn A, Merza M, Ros C, Lindholmc A, Palfl V, Hannant D, Belak S: Prevalence of equine herpesvirus types 2 and 5 in horse populations by using type-specific PCR assays. Vet Res 33:251-259, 2002
21. Panoskaltisis-Motari AB, Bucy RP: In situ hybridization with digoxygenin-labeled RNA probes: facts and artifacts. Biotechniques 18:300-307, 1995
22. Patel JR, Heldens J: Equine herpesviruses 1 (EHV-1) and 4 (EHV-4) - epidemiology, disease and immunoprophylaxis: a brief review. Vet J 170:14-23, 2005
23. Reubel GH, Crabb BS, Studdert MJ: Diagnosis of equine gammaherpesvirus 2 and 5 infections by polymerase chain reaction. Arch Virol 140:1049-1060, 1995
24. Rovnak J, Quackenbush SL, Reyes RA, Baines JD, Parrish CR, Casey JW: Detection of a novel bovine lymphotropic herpesvirus. J Virol 72:4237-4242, 1998
25. Ruszczyk A, Cywinska A, Banbura MW: Equine herpes virus 2 infection in horse populations in Poland. Acta Virol 48:189-192, 2004
26. Sarawar SR, Lee BJ, Anderson M, Teng YC, Zuberi R, Von Gesjen S: Chemokine induction and leukocyte trafficking to the lungs during murine gammaherpesvirus 68 (MHV-68) infection. Virology 293:54-62, 2002
27. Schwartz LW, Knight HD, Whittig LD, Malloy RL, Abraham JL, Tyler NK: Silicate pneumoconiosis and pulmonary fibrosis in horses from the Monterey-Carmel peninsula. Chest 80:82-85, 1981
28. Studdert MJ, Turner AJ, Peterson JE: Equine herpesviruses. I. Isolation and characterisation of equine rhinopneumonitis virus and other equine herpesviruses from horses. Aust Vet J 46:83-89, 1970
29. Tang YW, Johnson JE, Browning PJ, Cruz-Gervis RA, Davis A, Graham BS, Brigham KL, Oates JA Jr, Loyd JE, Stecenko AA: Herpesvirus DNA is consistently detected in lungs of patients with idiopathic pulmonary fibrosis. J Clin Microbiol 41:2633-2640, 2003
30. Telford EA, Studdert MJ, Agius CT, Watson MS, Aird HC, Davison AJ: Equine herpesviruses 2 and 5 are gamma-herpesviruses. Virology 195:492-499, 1993
31. VanDevanter DR, Warrener P, Bennett L, Schultz ER, Coulter S, Garber RL, Rose TM: Detection and analysis of diverse herpesviral species by consensus primer PCR. J Clin Microbiol 34:1666-1671, 1996
32. Vassallo R: Viral-induced inflammation in interstitial lung diseases. Semin Respir Infect 18:55-60, 2003
33. Wang L, Raidal SL, Pizzirani A, Wilcox GE: Detection of respiratory herpesviruses in foals and adult horses determined by nested multiplex PCR. Vet Microbiol 121:18-28, 2007
34. Wang R, Zagariya A, Ang E, Ibarra-Sunga O, Uhal BD: Fas-induced apoptosis of alveolar epithelial cells requires ANG II generation and receptor interaction. Am J Physiol 277:L1245-L1250, 1999
35. Wilkins PA: Interstitial pneumonia. In: Current Therapy in Equine Medicine, ed. Robinson NE, 5th ed., pp. 425-429. WB Saunders Co., Philadelphia, PA, 2003
36. Winder C, Ehrensperger F, Hermann M, Howald B, von Fellenberg R: Interstitial pneumonia in the horse: two unusual cases. Equine Vet J 20:298-301, 1988