Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules

Toxicology and Applied Pharmacology

Volumn 260, Issue 1, 2012, Pages 17-26

  Duan, Hongying ^a,d   Yoshimura, Kazunori ^a,e   Kobayashi, Nobuharu ^a   Sugiyama, Kazuo ^a,f   Sawada, Jun ichi ^b,g   Saito, Yoshiro ^b   Morisseau, Christophe ^c   Hammock, Bruce D ^c   Akatsuka, Toshitaka ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^e NIHON INSTITUTE OF MEDICAL SCIENCE   (Japan)

^f KEIO UNIVERSITY   (Japan)

^g PHARMACEUTICALS AND MEDICAL DEVICES AGENCY   (Japan)

Author keywords

Drug metabolism; Immunoassay; Microsomal epoxide hydrolase; Monoclonal antibodies; Tumor associated antigens

Indexed keywords

EPITOPE; EPOXIDE HYDROLASE; MONOCLONAL ANTIBODY;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN DETECTION; ANTIGEN STRUCTURE; ARTICLE; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CULTURE MEDIUM; EPITOPE MAPPING; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MICROSOME; MOUSE; NONHUMAN; PROTEIN CONFORMATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; ENDOPLASMIC RETICULUM; EPITOPES; EPOXIDE HYDROLASES; GLIOBLASTOMA; HUMANS; LIVER NEOPLASMS; PRECANCEROUS CONDITIONS;

HEPATITIS C VIRUS;

EID: 84858294284     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.01.023     Document Type: Article

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