Host phenotype characteristics and MC1R in relation to early-onset basal cell carcinoma

Journal of Investigative Dermatology

Volumn 132, Issue 4, 2012, Pages 1272-1279

  Ferrucci, Leah M ^a   Cartmel, Brenda ^a,b   Molinaro, Annette M ^a,b   Gordon, Patricia B ^c   Leffell, David J ^b,c   Bale, Allen E ^b,c   Mayne, Susan T ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE CANCER CENTER   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MELANOCORTIN 1 RECEPTOR;

ADULT; ARTICLE; BASAL CELL CARCINOMA; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SKIN BIOPSY; SUN EXPOSURE;

EID: 84858293860     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.402     Document Type: Article

References (47)

1. American Cancer Society (2011) Skin cancer: Basal and squamous cell. /http:// www.cancer.org/cancer/skincancer-basalandsquamouscell/detailedguide/ skin-cancer-basal-And-squamous-cell-what-is-basal-And-squamous-cellS accessed May 2011
2. Arits AH, Schlangen MH, Nelemans PJ et al. (2011) Trends in the incidence of basal cell carcinoma by histopathological subtype. J Eur Acad Dermatol Venereol 25:565-9
3. Bakos RM, Kriz M, Muhlstadt M et al. (2011) Risk factors for early-onset basal cell carcinoma in a German institution. Eur J Dermatol 2011 21:705-9
4. Bastiaens MT, ter Huurne JA, Kielich C et al. (2001) Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair. Am J Hum Genet 68:884-94
5. Bath-Hextall F, Leonardi-Bee J, Smith C et al. (2007) Trends in incidence of skin basal cell carcinoma. Additional evidence from a UK primary care database study. Int J Cancer 121:2105-8
6. Birch-Johansen F, Jensen A, Mortensen L et al. (2010) Trends in the incidence of nonmelanoma skin cancer in Denmark 1978-2007: Rapid incidence increase among young Danish women. Int J Cancer 127:2190-8
7. Box NF, Duffy DL, Irving RE et al. (2001) Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma. J Invest Dermatol 116:224-9
8. Box NF, Wyeth JR, O'Gorman LE et al. (1997) Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair. Hum Mol Genet 6:1891-7
9. Boyd AS, Shyr Y, King LE Jr (2002) Basal cell carcinoma in young women: An evaluation of the association of tanning bed use and smoking. J Am Acad Dermatol 46:706-9
10. Christenson LJ, Borrowman TA, Vachon CM et al. (2005) Incidence of basal cell and squamous cell carcinomas in a population younger than 40 years. JAMA 294:681-90
11. Dessinioti C, Antoniou C, Katsambas A et al. (2010) Basal cell carcinoma: What's new under the sun. Photochem Photobiol 86:481-91
12. Doherty VR, Brewster DH, Jensen S et al. (2010) Trends in skin cancer incidence by socioeconomic position in Scotland, 1978-2004. Br J Cancer 102:1661-4
13. Dwyer T, Stankovich JM, Blizzard L et al. (2004) Does the addition of information on genotype improve prediction of the risk of melanoma and nonmelanoma skin cancer beyond that obtained from skin phenotype? Am J Epidemiol 159:826-33
14. Eves P, Haycock J, Layton C et al. (2003) Anti-inflammatory and anti-invasive effects of alpha-melanocyte-stimulating hormone in human melanoma cells. Br J Cancer 89:2004-15
15. Flohil SC, de Vries E, Neumann HA et al. (2011) Incidence, prevalence and future trends of primary basal cell carcinoma in the Netherlands. Acta Derm Venereol 91:24-30
16. Getting SJ (2006) Targeting melanocortin receptors as potential novel therapeutics. Pharmacol Ther 111:1-15
17. Gorlin RJ, Goltz RW (1960) Multiple nevoid basal-cell epithelioma, jaw cysts and bifid rib. A syndrome. N Engl J Med 262:908-12
18. Gudbjartsson DF, Sulem P, Stacey SN et al. (2008) ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. Nat Genet 40:886-91
19. Han J, Kraft P, Colditz GA et al. (2006) Melanocortin 1 receptor variants and skin cancer risk. Int J Cancer 119:1976-84
20. Hogan DJ, To T, Gran L et al. (1989) Risk factors for basal cell carcinoma. Int J Dermatol 28:591-4
21. Housman TS, Feldman SR, Williford PM et al. (2003) Skin cancer is among the most costly of all cancers to treat for the Medicare population. J Am Acad Dermatol 48:425-9
22. Ichii-Jones F, Lear JT, Heagerty AH et al. (1998) Susceptibility to melanoma: Influence of skin type and polymorphism in the melanocyte stimulating hormone receptor gene. J Invest Dermatol 111:218-21
23. International Agency for Research on Cancer Working Group on artificial ultraviolet (UV) light and skin cancer (2007) The association of use of sunbeds with cutaneous malignant melanoma and other skin cancers: A systematic review. Int J Cancer 120:1116-22
24. Kanetsky PA, Ge F, Najarian D et al. (2004) Assessment of polymorphic variants in the melanocortin-1 receptor gene with cutaneous pigmentation using an evolutionary approach. Cancer Epidemiol Biomarkers Prev 13:808-19
25. Kanetsky PA, Panossian S, Elder DE et al. (2010) Does MC1R genotype convey information about melanoma risk beyond risk phenotypes? Cancer 116:2416-28
26. Karagas MR, Greenberg ER, Spencer SK et al. (1999) Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA. New Hampshire Skin Cancer Study Group. Int J Cancer 81:555-9
27. Kennedy C, ter Huurne J, Berkhout M et al. (2001) Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J Invest Dermatol 117:294-300
28. Kiiski V, de Vries E, Flohil SC et al. (2010) Risk factors for single and multiple basal cell carcinomas. Arch Dermatol 146:848-55
29. Koppula SV, Robbins LS, Lu D et al. (1997) Identification of common polymorphisms in the coding sequence of the human MSH receptor (MCIR) with possible biological effects. Hum Mutat 9:30-5
30. Landi MT, Kanetsky PA, Tsang S et al. (2005) MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population. J Natl Cancer Inst 97:998-1007
31. Levi F, Te VC, Randimbison L et al. (2001) Trends in skin cancer incidence in Vaud: An update, 1976-1998. Eur J Cancer Prev 10:371-3
32. Liboutet M, Portela M, Delestaing G et al. (2006) MC1R and PTCH gene polymorphism in French patients with basal cell carcinomas. J Invest Dermatol 126:1510-7
33. Madan V, Lear JT, Szeimies RM (2010) Non-melanoma skin cancer. Lancet 375:673-85
34. Maia M, Proenca NG, de Moraes JC (1995) Risk factors for basal cell carcinoma: A case-control study. Revista de Saude Publica 29:27-37
35. Naldi L, DiLandro A, D'Avanzo B et al. (2000) Host-related and environmental risk factors for cutaneous basal cell carcinoma: Evidence from an Italian case-control study. J Am Acad Dermatol 42:446-52
36. Nan H, Kraft P, Hunter DJ et al. (2009) Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians. Int J Cancer 125:909-17
37. Naysmith L, Waterston K, Ha T et al. (2004) Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status. J Invest Dermatol 122:423-8
38. Palmer JS, Duffy DL, Box NF et al. (2000) Melanocortin-1 receptor polymorphisms and risk of melanoma: Is the association explained solely by pigmentation phenotype? Am J Hum Genet 66:176-85
39. Robinson S, Dixon S, August S et al. (2010) Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo. J Invest Dermatol 130:1904-13
40. Rogers HW, Weinstock MA, Harris AR et al. (2010) Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol 146:283-7
41. Scherer D, Bermejo JL, Rudnai P et al. (2008) MC1R variants associated susceptibility to basal cell carcinoma of skin: Interaction with host factors and XRCC3 polymorphism. Int J Cancer 122:1787-93
42. Scherer D, Kumar R (2010) Genetics of pigmentation in skin cancer-A review. Mutat Res 705:141-53
43. Smith R, Healy E, Siddiqui S et al. (1998) Melanocortin 1 receptor variants in an Irish population. J Invest Dermatol 111:119-22
44. Stacey SN, Sulem P, Masson G et al. (2009) New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 41:909-14
45. Valverde P, Healy E, Jackson I et al. (1995) Variants of the melanocytestimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat Genet 11:328-30
46. Vitasa BC, Taylor HR, Strickland PT et al. (1990) Association of nonmelanoma skin cancer and actinic keratosis with cumulative solar ultraviolet exposure in Maryland watermen. Cancer 65:2811-7
47. Zanetti R, Rosso S, Martinez C et al. (1996) The multicentre south European study 'Helios' I: Skin characteristics and sunburns in basal cell and squamous cell carcinomas of the skin. Br J Cancer 73:1440-5