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Volumn 130, Issue 7, 2010, Pages 1904-1913

Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo

Author keywords

[No Author keywords available]

Indexed keywords

EUMELANIN; MELANIN; PHEOMELANIN; PROTEIN P53; PYRIMIDINE DIMER;

EID: 77953596353     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.48     Document Type: Article
Times cited : (35)

References (43)
  • 1
    • 33846554676 scopus 로고    scopus 로고
    • Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation
    • April CS, Barsh GS (2007) Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. PLoS Genet 3:e9
    • (2007) PLoS Genet , vol.3
    • April, C.S.1    Barsh, G.S.2
  • 2
    • 5144232482 scopus 로고    scopus 로고
    • Mutation spectra of epidermal p53 clones adjacent to basal cell carcinoma and squamous cell carcinoma
    • Bäckvall H, Strömberg S, Gustafsson A. et al. (2004) Mutation spectra of epidermal p53 clones adjacent to basal cell carcinoma and squamous cell carcinoma. Exp Dermatol 13:643-650
    • (2004) Exp Dermatol , vol.13 , pp. 643-650
    • Bäckvall, H.1    Strömberg, S.2    Gustafsson, A.3
  • 3
    • 0035068231 scopus 로고    scopus 로고
    • Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair
    • Bastiaens MT, ter Huurne JA, Kielich C et al. (2001) Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair. Am J Hum Genet 68:884-894
    • (2001) Am J Hum Genet , vol.68 , pp. 884-894
    • Bastiaens, M.T.1    Ter Huurne, J.A.2    Kielich, C.3
  • 4
    • 26444449038 scopus 로고    scopus 로고
    • Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk
    • Beaumont KA, Newton RA, Smit DJ et al. (2005) Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. Hum Mol Genet 14:2145-2154
    • (2005) Hum Mol Genet , vol.14 , pp. 2145-2154
    • Beaumont, K.A.1    Newton, R.A.2    Smit, D.J.3
  • 5
    • 34548385653 scopus 로고    scopus 로고
    • Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles
    • Beaumont KA, Shekar SN, Newton RA et al. (2007) Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles. Hum Mol Genet 16:2249-2260
    • (2007) Hum Mol Genet , vol.16 , pp. 2249-2260
    • Beaumont, K.A.1    Shekar, S.N.2    Newton, R.A.3
  • 7
    • 14044260140 scopus 로고    scopus 로고
    • Alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage
    • Böhm M, Wolff I, Scholzen TE et al. (2005) alpha-Melanocyte- stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage. J Biol Chem 280:5795-5802
    • (2005) J Biol Chem , vol.280 , pp. 5795-5802
    • Böhm, M.1    Wolff, I.2    Scholzen, T.E.3
  • 8
    • 0035116287 scopus 로고    scopus 로고
    • Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma
    • Box NF, Duffy DL, Irving RE et al. (2001) Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma. J Invest Dermatol 116:224-229
    • (2001) J Invest Dermatol , vol.116 , pp. 224-229
    • Box, N.F.1    Duffy, D.L.2    Irving, R.E.3
  • 9
    • 0031791431 scopus 로고    scopus 로고
    • Incidence rates of skin cancer in Townsville, Australia
    • Buettner PG, Raasch BA (1998) Incidence rates of skin cancer in Townsville, Australia. Int J Cancer 78:587-593
    • (1998) Int J Cancer , vol.78 , pp. 587-593
    • Buettner, P.G.1    Raasch, B.A.2
  • 11
    • 0020570598 scopus 로고
    • A mathematical model for ultraviolet optics in skin
    • Diffey BL (1983) A mathematical model for ultraviolet optics in skin. Phys Med Biol 28:647-657
    • (1983) Phys Med Biol , vol.28 , pp. 647-657
    • Diffey, B.L.1
  • 12
    • 25144506469 scopus 로고    scopus 로고
    • Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors
    • Gandini S, Sera F, Cattaruzza MS et al. (2005) Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors. Eur J Cancer 41:2040-2059
    • (2005) Eur J Cancer , vol.41 , pp. 2040-2059
    • Gandini, S.1    Sera, F.2    Cattaruzza, M.S.3
  • 13
    • 0018889703 scopus 로고
    • Mutagenicity of melanin from human red hair
    • Harsanyi ZP, Post PW, Brinkmann JP et al. (1980) Mutagenicity of melanin from human red hair. Experientia 36:291-292
    • (1980) Experientia , vol.36 , pp. 291-292
    • Harsanyi, Z.P.1    Post, P.W.2    Brinkmann, J.P.3
  • 14
    • 0034712537 scopus 로고    scopus 로고
    • Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair
    • Healy E, Flannagan N, Ray A et al. (2000) Melanocortin-1-receptor gene and sun sensitivity in individuals without red hair. Lancet 355:1072-1073
    • (2000) Lancet , vol.355 , pp. 1072-1073
    • Healy, E.1    Flannagan, N.2    Ray, A.3
  • 15
    • 0035504443 scopus 로고    scopus 로고
    • Functional variation of MC1R alleles from red-haired individuals
    • Healy E, Jordan SA, Budd PS et al. (2001) Functional variation of MC1R alleles from red-haired individuals. Hum Mol Genet 10:2397-2402
    • (2001) Hum Mol Genet , vol.10 , pp. 2397-2402
    • Healy, E.1    Jordan, S.A.2    Budd, P.S.3
  • 16
    • 19544392728 scopus 로고    scopus 로고
    • Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation
    • Hennessy A, Oh C, Diffey B et al. (2005) Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation. Pigment Cell Res 18:220-223
    • (2005) Pigment Cell Res , vol.18 , pp. 220-223
    • Hennessy, A.1    Oh, C.2    Diffey, B.3
  • 17
    • 0042733275 scopus 로고    scopus 로고
    • Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: A comparative review
    • Ito S, Wakamatsu K (2003) Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review. Pigment Cell Res 16:523-531
    • (2003) Pigment Cell Res , vol.16 , pp. 523-531
    • Ito, S.1    Wakamatsu, K.2
  • 18
    • 0030459428 scopus 로고    scopus 로고
    • Frequent clones of p53-mutated keratinocytes in normal human skin
    • Jonason AS, Kunala S, Price GJ et al. (1996) Frequent clones of p53-mutated keratinocytes in normal human skin. Proc Natl Acad Sci USA 93: 14025-14029
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14025-14029
    • Jonason, A.S.1    Kunala, S.2    Price, G.J.3
  • 19
    • 20144377250 scopus 로고    scopus 로고
    • Alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes
    • Kadekaro AL, Kavanagh R, Kanto H et al. (2005) alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes. Cancer Res 65:4292-4299
    • (2005) Cancer Res , vol.65 , pp. 4292-4299
    • Kadekaro, A.L.1    Kavanagh, R.2    Kanto, H.3
  • 20
    • 34247249893 scopus 로고    scopus 로고
    • Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development
    • Kato M, Ohgami N, Kawamoto Y et al. (2007) Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development. J Invest Dermatol 127:1244-1249
    • (2007) J Invest Dermatol , vol.127 , pp. 1244-1249
    • Kato, M.1    Ohgami, N.2    Kawamoto, Y.3
  • 21
    • 18144385454 scopus 로고    scopus 로고
    • Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice
    • Kramata P, Lu YP, Lou YR et al. (2005) Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice. Cancer Res 65:3577-3585
    • (2005) Cancer Res , vol.65 , pp. 3577-3585
    • Kramata, P.1    Lu, Y.P.2    Lou, Y.R.3
  • 22
    • 21244446712 scopus 로고    scopus 로고
    • MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population
    • Landi MT, Kanetsky PA, Tsang S et al. (2005) MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population. J Natl Cancer Inst 97:998-1007
    • (2005) J Natl Cancer Inst , vol.97 , pp. 998-1007
    • Landi, M.T.1    Kanetsky, P.A.2    Tsang, S.3
  • 23
    • 33745208440 scopus 로고    scopus 로고
    • MC1R and PTCH gene polymorphism in French patients with basal cell carcinomas
    • Liboutet M, Portela M, Delestaing G et al. (2006) MC1R and PTCH gene polymorphism in French patients with basal cell carcinomas. J Invest Dermatol 126:1510-1517
    • (2006) J Invest Dermatol , vol.126 , pp. 1510-1517
    • Liboutet, M.1    Portela, M.2    Delestaing, G.3
  • 24
  • 25
    • 14644405691 scopus 로고    scopus 로고
    • Cellular and molecular events leading to the development of skin cancer
    • Melnikova VO, Ananthaswamy HN (2005) Cellular and molecular events leading to the development of skin cancer. Mutat Res 571:91-106
    • (2005) Mutat Res , vol.571 , pp. 91-106
    • Melnikova, V.O.1    Ananthaswamy, H.N.2
  • 26
    • 0020624631 scopus 로고
    • Effects of ultraviolet-visible irradiation in the presence of melanin isolated from human black or red hair upon Ehrlich ascites carcinoma cells
    • Menon IA, Persad S, Ranadive NS et al. (1983) Effects of ultraviolet-visible irradiation in the presence of melanin isolated from human black or red hair upon Ehrlich ascites carcinoma cells. Cancer Res 43:3165-3169
    • (1983) Cancer Res , vol.43 , pp. 3165-3169
    • Menon, I.A.1    Persad, S.2    Ranadive, N.S.3
  • 27
    • 38649115315 scopus 로고    scopus 로고
    • Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure
    • Moan J, Porojnicu AC, Dahlback A et al. (2008) Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure. Proc Natl Acad Sci USA 105:668-673
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 668-673
    • Moan, J.1    Porojnicu, A.C.2    Dahlback, A.3
  • 28
    • 33748784343 scopus 로고    scopus 로고
    • Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation
    • Mouret S, Baudouin C, Charveron M et al. (2006) Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation. Proc Natl Acad Sci USA 103:13765-13770
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13765-13770
    • Mouret, S.1    Baudouin, C.2    Charveron, M.3
  • 29
    • 34047221962 scopus 로고    scopus 로고
    • Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency
    • Nijhof JG, van Pelt C, Mulder AA et al. (2007) Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency. Carcinogenesis 28:792-800
    • (2007) Carcinogenesis , vol.28 , pp. 792-800
    • Nijhof, J.G.1    Van Pelt, C.2    Mulder, A.A.3
  • 30
    • 33947232305 scopus 로고    scopus 로고
    • Oncology Study Group of the Italian Group for Epidemiologic Research in Dermatology (GISED) (2007) Risk factors for histological types and anatomic sites of cutaneous basal-cell carcinoma: An Italian case-control study
    • Pelucchi C, Di Landro A, Naldi L, et al., Oncology Study Group of the Italian Group for Epidemiologic Research in Dermatology (GISED) (2007) Risk factors for histological types and anatomic sites of cutaneous basal-cell carcinoma: an Italian case-control study. J Invest Dermatol 127:935-944
    • J Invest Dermatol , vol.127 , pp. 935-944
    • Pelucchi, C.1    Di Landro, A.2    Naldi, L.3
  • 31
    • 0023935917 scopus 로고
    • Unreliability of self-reported burning tendency and tanning ability
    • Rampen FH, Fleuren BA, de Boo TM et al. (1988) Unreliability of self-reported burning tendency and tanning ability. Arch Dermatol 124:885-888
    • (1988) Arch Dermatol , vol.124 , pp. 885-888
    • Rampen, F.H.1    Fleuren, B.A.2    De Boo, T.M.3
  • 32
    • 27944509203 scopus 로고    scopus 로고
    • Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice
    • Rebel H, Kram N, Westerman A et al. (2005) Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice. Carcinogenesis 26:2123-2130
    • (2005) Carcinogenesis , vol.26 , pp. 2123-2130
    • Rebel, H.1    Kram, N.2    Westerman, A.3
  • 33
    • 0037079229 scopus 로고    scopus 로고
    • Human melanocortin 1 receptor (MC1R) gene variants alter melanoma cell growth and adhesion to extracellular matrix
    • Robinson SJ, Healy E (2002) Human melanocortin 1 receptor (MC1R) gene variants alter melanoma cell growth and adhesion to extracellular matrix. Oncogene 21:8037-8046
    • (2002) Oncogene , vol.21 , pp. 8037-8046
    • Robinson, S.J.1    Healy, E.2
  • 34
    • 0041909920 scopus 로고    scopus 로고
    • The sunburn cell revisited: An update on mechanistic aspects
    • Sheehan JM, Young AR (2002) The sunburn cell revisited: an update on mechanistic aspects. Photochem Photobiol Sci 1:365-377
    • (2002) Photochem Photobiol Sci , vol.1 , pp. 365-377
    • Sheehan, J.M.1    Young, A.R.2
  • 35
    • 36549071998 scopus 로고    scopus 로고
    • Genetic determinants of hair, eye and skin pigmentation in Europeans
    • Sulem P, Gudbjartsson DF, Stacey SN et al. (2007) Genetic determinants of hair, eye and skin pigmentation in Europeans. Nat Genet 39: 1443-1452
    • (2007) Nat Genet , vol.39 , pp. 1443-1452
    • Sulem, P.1    Gudbjartsson, D.F.2    Stacey, S.N.3
  • 36
    • 0033402753 scopus 로고    scopus 로고
    • Low frequency of genetic change in p53 immunopositive clones in human epidermis
    • Tabata H, Nagano T, Ray AJ et al. (1999) Low frequency of genetic change in p53 immunopositive clones in human epidermis. J Invest Dermatol 113:972-976
    • (1999) J Invest Dermatol , vol.113 , pp. 972-976
    • Tabata, H.1    Nagano, T.2    Ray, A.J.3
  • 37
    • 6344254298 scopus 로고    scopus 로고
    • Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin
    • Takeuchi S, Zhang W, Wakamatsu K et al. (2004) Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Proc Natl Acad Sci USA 101:15076-15081
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15076-15081
    • Takeuchi, S.1    Zhang, W.2    Wakamatsu, K.3
  • 38
    • 0025779123 scopus 로고
    • Pheomelanin as well as eumelanin is present in human epidermis
    • Thody AJ, Higgins EM, Wakamatsu K et al. (1991) Pheomelanin as well as eumelanin is present in human epidermis. J Invest Dermatol 97:340-344
    • (1991) J Invest Dermatol , vol.97 , pp. 340-344
    • Thody, A.J.1    Higgins, E.M.2    Wakamatsu, K.3
  • 39
    • 0028786945 scopus 로고
    • Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
    • Valverde P, Healy E, Jackson I et al. (1995) Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat Genet 11:328-330
    • (1995) Nat Genet , vol.11 , pp. 328-330
    • Valverde, P.1    Healy, E.2    Jackson, I.3
  • 40
    • 0036016302 scopus 로고    scopus 로고
    • Advanced chemical methods in melanin determination
    • Wakamatsu K, Ito S (2002) Advanced chemical methods in melanin determination. Pigment Cell Res 15:174-183
    • (2002) Pigment Cell Res , vol.15 , pp. 174-183
    • Wakamatsu, K.1    Ito, S.2
  • 41
    • 0031680660 scopus 로고    scopus 로고
    • Pheomelanin photosensitizes UVA-induced DNA damage in cultured human mela-nocytes
    • Wenczl E, Van der Schans GP, Roza L et al. (1998) Pheomelanin photosensitizes UVA-induced DNA damage in cultured human mela-nocytes. J Invest Dermatol 111:678-682
    • (1998) J Invest Dermatol , vol.111 , pp. 678-682
    • Wenczl, E.1    Van Der Schans, G.P.2    Roza, L.3
  • 42
    • 33746572250 scopus 로고    scopus 로고
    • Human skin responses to UV radiation: Pigment in the upper epidermis protects against DNA damage in the lower epidermis and facilitates apoptosis
    • Yamaguchi Y, Takahashi K, Zmudzka BZ et al. (2006) Human skin responses to UV radiation: pigment in the upper epidermis protects against DNA damage in the lower epidermis and facilitates apoptosis. FASEB J 20:1486-1488
    • (2006) FASEB J , vol.20 , pp. 1486-1488
    • Yamaguchi, Y.1    Takahashi, K.2    Zmudzka, B.Z.3
  • 43
    • 3042551488 scopus 로고    scopus 로고
    • XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis
    • Yamazaki F, Okamoto H, Miyauchi-Hashimoto H et al. (2004) XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis. J Invest Dermatol 123: 220-228
    • (2004) J Invest Dermatol , vol.123 , pp. 220-228
    • Yamazaki, F.1    Okamoto, H.2    Miyauchi-Hashimoto, H.3


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