Association between BclI polymorphism in the NR3C1 gene and in vitro individual variations in lymphocyte responses to methylprednisolone

British Journal of Clinical Pharmacology

Volumn 73, Issue 4, 2012, Pages 651-655

  Cuzzoni, Eva ^a   De Iudicibus, Sara ^a   Bartoli, Fiora ^a   Ventura, Alessandro ^a,b   Decorti, Giuliana ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

Author keywords

BclI polymorphism; Glucocorticoid sensitivity; Lymphocyte proliferation assay

Indexed keywords

CONCANAVALIN A; METHYLPREDNISOLONE;

ADULT; ARTICLE; CELL PROLIFERATION; DOSE RESPONSE; DRUG INHIBITION; DRUG RESPONSE; FEMALE; GENE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MALE; NORMAL HUMAN; NR3C1 GENE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHARMACOGENETICS; PRIORITY JOURNAL; PROTO ONCOGENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ADULT; APOPTOSIS REGULATORY PROTEINS; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENOTYPE; GLUCOCORTICOIDS; HUMANS; LYMPHOCYTES; MALE; METHYLPREDNISOLONE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, GLUCOCORTICOID; YOUNG ADULT;

EID: 84858263627     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2011.04130.x     Document Type: Article

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