Anion size modulates salt taste in rats

Journal of Neurophysiology

Volumn 107, Issue 6, 2012, Pages 1632-1648

  Breza, Joseph M ^a   Contreras, Robert J ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Chorda tympani; Electrophysiology; Epithelial sodium channel; Geniculate ganglion; Transient receptor potential vanilloid 1

Indexed keywords

4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; AMMONIUM CHLORIDE; ANION; BENZAMIL; CETYLPYRIDINIUM SALT; CITRIC ACID; EPITHELIAL SODIUM CHANNEL; GLUCONATE SODIUM; QUININE; SALIVA SUBSTITUTE; SODIUM CHANNEL; SODIUM CHLORIDE; SOLVENT; SUCROSE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STIMULATION; CELL STRUCTURE; CHORDA TYMPANI; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; EVOKED RESPONSE; FACIAL NERVE; GUSTATORY SYSTEM; INFORMATION; LATENT PERIOD; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE CELL ANALYSIS; TASTE BUD;

ANIMALS; CHORDA TYMPANI NERVE; EPITHELIAL SODIUM CHANNEL; MALE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; TASTE; TASTE PERCEPTION; TONGUE; TRPV CATION CHANNELS;

EID: 84858233324     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00621.2011     Document Type: Article

References (45)

1. Bealer SL. Intensity coding in the transient portion of the rat chorda tympani response. J Comp Physiol Psychol 92: 185-195, 1978.
2. Beidler LM. A theory of taste stimulation. J Gen Physiol 38: 133-139, 1954.
3. Blough DS, Blough PM. Animal psychophysics. In: Handbook of Operant Behavior, edited by Honig WK, Staddon JER. Englewood Cliffs, NJ: Prentice-Hall, 1977.
4. Breza JM, Curtis KS, Contreras RJ. Monosodium glutamate but not linoleic acid differentially activates gustatory neurons in the rat geniculate ganglion. Chem Senses 32: 833-846, 2007.
5. Breza JM, Curtis KS, Contreras RJ. Temperature modulates taste responsiveness and stimulates gustatory neurons in the rat geniculate ganglion. J Neurophysiol 95: 674-685, 2006.
6. Breza JM, Nikonov AA, Contreras RJ. Response latency to lingual taste stimulation distinguishes neuron types within the geniculate ganglion. J Neurophysiol 103: 1771-1784, 2010.
7. Chandrashekar J, Kuhn C, Oka Y, Yarmolinsky DA, Hummler E, Ryba NJ, Zuker CS. The cells and peripheral representation of sodium taste in mice. Nature 464: 297-301, 2010.
8. Cohen J. A power primer. Psychol Bull 112: 155-159, 1992.
9. Contreras RJ, Lundy RF. Gustatory neuron types in the periphery: a functional perspective. Physiol Behav 69: 41-52, 2000.
10. Delwiche JF, Halpern BP, Desimone JA. Anion size of sodium salts and simple taste reaction times. Physiol Behav 66: 27-32, 1999.
11. Desimone JA, Lyall V, Heck GL, Phan TH, Alam RI, Feldman GM, Buch RM. A novel pharmacological probe links the amiloride-insensitive NaCl, KCl, and NH(4)Cl chorda tympani taste responses. J Neurophysiol 86: 2638-2641, 2001.
12. Elliott EJ, Simon SA. The anion in salt taste: a possible role for paracellular pathways. Brain Res 535: 9-17, 1990.
13. Frank ME, Contreras RJ, Hettinger TP. Nerve fibers sensitive to ionic taste stimuli in chorda tympani of the rat. J Neurophysiol 50: 941-960, 1983.
14. Geran LC, Spector AC. Amiloride increases sodium chloride taste detection threshold in rats. Behav Neurosci 114: 623-634, 2000a.
15. Geran LC, Spector AC. Sodium taste detectability in rats is independent of anion size: the psychophysical characteristics of the transcellular sodium taste transduction pathway. Behav Neurosci 114: 1229-1238, 2000b.
16. Geran LC, Travers SP. Single neurons in the nucleus of the solitary tract respond selectively to bitter taste stimuli. J Neurophysiol 96: 2513-2527, 2006.
17. Gleiberman L. Blood pressure and dietary salt in human populations. Ecol Food Nutr 2: 143-156, 1973.
18. Guenthner CJ, McCaughey SA, Tordoff MG, Baird JP. Licking for taste solutions by potassium-deprived rats: specificity and mechanisms. Physiol Behav 93: 937-946, 2008.
19. Halpern BP, Tapper DN. Taste stimuli: quality coding time. Science 171: 1256-1258, 1971.
20. Heck GL, Mierson S, DeSimone JA. Salt taste transduction occurs through an amiloride-sensitive sodium transport pathway. Science 223: 403-405, 1984.
21. Hettinger TP, Frank ME. Specificity of amiloride inhibition of hamster taste responses. Brain Res 513: 24-34, 1990.
22. James WP, Ralph A, Sanchez-Castillo CP. The dominance of salt in manufactured food in the sodium intake of affluent societies. Lancet 1: 426-429, 1987.
23. Lawhern V, Nikonov AA, Wu W, Contreras RJ. Spike rate and spike timing contributions to coding taste quality information in rat periphery. Front Integr Neurosci 5: 18, 2011.
24. Lundy RF Jr, Contreras RJ. Gustatory neuron types in rat geniculate ganglion. J Neurophysiol 82: 2970-2988, 1999.
25. Lyall V, Alam RI, Phan DQ, Ereso GL, Phan TH, Malik SA, Montrose MH, Chu S, Heck GL, Feldman GM, DeSimone JA. Decrease in rat taste receptor cell intracellular pH is the proximate stimulus in sour taste transduction. Am J Physiol Cell Physiol 281: C1005-C1013, 2001.
26. Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Alam RI, Russell OF, Malik SA, Bigbee JW, DeSimone JA. The mammalian amilorideinsensitive non-specific salt taste receptor is a vanilloid receptor-1 variant. J Physiol 558: 147-159, 2004.
27. Lyall V, Heck GL, Vinnikova AK, Ghosh S, Phan TH, Desimone JA. A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor. Chem Senses 30, Suppl 1: i42-i43, 2005.
28. Mancilha-Carvalho JJ, de Oliveira R, Esposito RJ. Blood pressure and electrolyte excretion in the Yanomamo Indians, an isolated population. J Hum Hypertens 3: 309-314, 1989.
29. Markison S, Spector AC. Amiloride is an ineffective conditioned stimulus in taste aversion learning. Chem Senses 20: 559-563, 1995.
30. Ninomiya Y, Funakoshi M. Amiloride inhibition of responses of rat single chorda tympani fibers to chemical and electrical tongue stimulations. Brain Res 451: 319-325, 1988.
31. Ossebaard CA, Smith DV. Amiloride suppresses the sourness of NaCl and LiCl. Physiol Behav 60: 1317-1322, 1996.
32. Ossebaard CA, Smith DV. Effect of amiloride on the taste of NaCl, Nagluconate and KCl in humans: implications for Na_ receptor mechanisms. Chem Senses 20: 37-46, 1995.
33. Page LB. Epidemiologic evidence on the etiology of human hypertension and its possible prevention. Am Heart J 91: 527-534, 1976.
34. Rehnberg BG, MacKinnon BI, Hettinger TP, Frank ME. Anion modulation of taste responses in sodium-sensitive neurons of the hamster chorda tympani nerve. J Gen Physiol 101: 453-465, 1993.
35. Ruiz C, Gutknecht S, Delay E, Kinnamon S. Detection of NaCl and KCl in TRPV1 knockout mice. Chem Senses 31: 813-820, 2006.
36. Smith DV, Travers JB. A metric for the breadth of tuning of gustatory neurons. Chem Senses Flav 4: 215-229, 1979.
37. Sollars SI, Hill DL. In vivo recordings from rat geniculate ganglia: taste response properties of individual greater superficial petrosal and chorda tympani neurones. J Physiol 564: 877-893, 2005.
38. Spector AC, Guagliardo NA, St. John SJ. Amiloride disrupts NaCl versus KCl discrimination performance: implications for salt taste coding in rats. J Neurosci 16: 8115-8122, 1996.
39. Spector AC, Travers SP. The representation of taste quality in the mammalian nervous system. Behav Cogn Neurosci Rev 4: 143-191, 2005.
40. St. John SJ, Hallagan LD. Psychophysical investigations of cetylpyridinium chloride in rats: its inherent taste and modifying effects on salt taste. Behav Neurosci 119: 265-279, 2005.
41. Treesukosol Y, Lyall V, Heck GL, DeSimone JA, Spector AC. A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice. Am J Physiol Regul Integr Comp Physiol 292: R1799-R1809, 2007.
42. van der Klaauw NJ, Smith DV. Taste quality profiles for fifteen organic and inorganic salts. Physiol Behav 58: 295-306, 1995.
43. Ye Q, Heck GL, DeSimone JA. The anion paradox in sodium taste reception: resolution by voltage-clamp studies. Science 254: 724-726, 1991.
44. + salts in the rat: implications for gustatory transduction. J Gen Physiol 104: 885-907, 1994.
45. + salts: implications for the functional organization of taste receptor cells. J Neurophysiol 70: 167-178, 1993.