Smoking: Effects on multiple sclerosis susceptibility and disease progression

Therapeutic Advances in Neurological Disorders

Volumn 5, Issue 1, 2012, Pages 13-22

  Wingerchuk, Dean M ^a  

^a MAYO CLINIC   (United States)

Author keywords

causality; disease progression; multiple sclerosis; risk factors; smoking

Indexed keywords

HLA A ANTIGEN; HLA DRB1 ANTIGEN;

CASE CONTROL STUDY; CIGARETTE SMOKING; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EPSTEIN BARR VIRUS INFECTION; EXPERIMENTATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HEREDITY; HUMAN; INTERNAL CONSISTENCY; META ANALYSIS (TOPIC); MULTIPLE SCLEROSIS; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; RISK FACTOR; ULTRAVIOLET RADIATION;

EID: 84858216423     PISSN: 17562856     EISSN: 17562864     Source Type: Journal    
DOI: 10.1177/1756285611425694     Document Type: Review

References (59)

1. Antonovsky A. Leibowitz U. Smith H.A. Medalie J.M. Balogh M. Kats R. et al (1965) Epidemiologic study of multiple sclerosis in Israel. I. An overall review of methods and findings. Arch Neurol 13: 183–193.
2. Carlens C. Hergens M.P. Grunewald J. Ekbom A. Eklund A. Hoglund C.O. et al (2010) Smoking, use of moist snuff, and risk of chronic inflammatory diseases. Am J Respir Crit Care Med 181: 1217–1222.
3. Celius E.G. Smestad C. (2009) Change in sex ratio, disease course and age at diagnosis in Oslo MS patients through seven decades. Acta Neurol Scand Suppl 189: 27–29.
4. Chen H. Huang X. Guo X. Mailman R.B. Park Y. Kamel F. et al (2010) Smoking duration, intensity, and risk of Parkinson disease. Neurology 74: 878–884.
5. Compston A. Coles A. (2008) Multiple sclerosis. Lancet 372: 1502–1517.
6. Courville C.B. Maschmeyer J.E. Delay C.P. (1964) Effects of smoking on the acute exacerbations of multiple sclerosis. Bull Los Angel Neurol Soc 29: 1–6.
7. de Jager P.L. Chibnik L.B. Cui J. Reischl J. Lehr S. Simon K.C. et al (2009) Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score. Lancet Neurol 8: 1111–1119.
8. Di Pauli F. Reindl M. Ehling R. Schautzer F. Gneiss C. Lutterotti A. et al (2008) Smoking is a risk factor for early conversion to clinically definite multiple sclerosis. Mult Scler 14: 1026–1030.
9. Emre M. de Decker C. (1992) Effects of cigarette smoking on motor functions in patients with multiple sclerosis. Arch Neurol 49: 1243–1247.
10. Fusby J.S. Kassmeier M.D. Palmer V.L. Perry G.A. Anderson D.K. Hackfort B.T. et al (2010) Cigarette smoke-induced effects on bone marrow B-cell subsets and CD4+:CD8+ T-cell ratios are reversed by smoking cessation: influence of bone mass on immune cell response to and recovery from smoke exposure. Inhal Toxicol 22: 785–796.
11. Ghadirian P. Dadgostar B. Azani R. Maisonneuve P. (2001) A case-control study of the association between socio-demographic, lifestyle and medical history factors and multiple sclerosis. Can J Public Health 92: 281–285.
12. Gold S.M. Voskuhl R.R. (2009) Estrogen treatment in multiple sclerosis. J Neurol Sci 286: 99–103.
13. Handel A.E. Ebers G.C. Ramagopalan S.V. (2009) Epigenetics: molecular mechanisms and implications for disease. Trends Mol Med 16: 7–16.
14. Handel A.E. Giovannoni G. Ebers G.C. Ramagopalan S.V. 2010a Environmental factors and their timing in adult-onset multiple sclerosis. Nat Rev Neurosci 6: 156–166.
15. Handel A.E. Joseph A. Ramagopalan S.V. 2010b Multiple sclerosis and lung cancer: an unexpected inverse association. QJM 103: 625–626.
16. Handel A.E. Williamson A.J. Disanto G. Dobson R. Giovannoni G. Ramagopalan S.V. (2011) Smoking and multiple sclerosis: an updated meta-analysis. PloS ONE 6: e16149.
17. Handunnetthi L. Ramagopalan S.V. Ebers G.C. Handunnetthi L. Ramagopalan S.V. Ebers G.C. (2010) Multiple sclerosis, vitamin D, and HLA-DRB1*15. Neurology 74: 1905–1910.
18. Harel-Meir M. Sherer Y. Shoenfeld Y. (2007) Tobacco smoking and autoimmune rheumatic diseases. Nat Clin Pract Rheumatol 3: 707–715.
19. Hawkes C.H. (2005) Are multiple sclerosis patients risk-takers?. QJM 98: 895–911.
20. Healy B.C. Ali E.N. Guttmann C.R. Chitnis T. Glanz B.I. Buckle G. et al (2009) Smoking and disease progression in multiple sclerosis. Arch Neurol 66: 858–864.
21. Hedstrom A.K. Baarnhielm M. Olsson T. Alfredsson L. (2009) Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis. Neurology 73: 696–701.
22. Hedstrom A.K. Baarnhielm M. Olsson T. Alfredsson L. (2011) Exposure to environmental tobacco smoke is associated with increased risk for multiple sclerosis. Mult Scler 17: 788–793.
23. Hedstrom A.K. Sundqvist E. Baarnhielm M. Nordin N. Hillert J. Kockum I. et al (2011) Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis. Brain 134: 653–664.
24. Hernan M.A. Jick S.S. Logroscino G. Olek M.J. Ascherio A. Jick H. et al (2005) Cigarette smoking and the progression of multiple sclerosis. Brain 128: 1461–1465.
25. Hernan M.A. Olek M.J. Ascherio A. (2001) Cigarette smoking and incidence of multiple sclerosis. Am J Epidemiol 154: 69–74.
26. International Multiple Sclerosis Genetics Consortium and Wellcome Trust Case Control Consortium 2. (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476: 214–219.
27. Jafari N. Hoppenbrouwers I.A. Hop W.C. Breteler M.M. Hintzen R.Q. Jafari N. et al (2009) Cigarette smoking and risk of MS in multiplex families. Mult Scler 15: 1363–1367.
28. Kallberg H. Ding B. Padyukov L. Bengtsson C. Ronnelid J. Klareskog L. et al (2011) Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke. Ann Rheum Dis 70: 508–511.
29. Koch M. van Harten A. Uyttenboogaart M. de Keyser J. (2007) Cigarette smoking and progression in multiple sclerosis. Neurology 69: 1515–1520.
30. Maghzi A.H. Ghazavi H. Ahsan M. Etemadifar M. Mousavi S. Khorvash F. et al (2010) Increasing female preponderance of multiple sclerosis in Isfahan, Iran: a population-based study. Mult Scler 16: 359–361.
31. Marrie R.A. Cutter G. Tyry T. Campagnolo D. Vollmer T. Marrie R.A. et al (2009) Smoking status over two years in patients with multiple sclerosis. Neuroepidemiology 32: 72–79.
32. Michnovicz J.J. Hershcopf R.J. Naganuma H. Bradlow H.L. Fishman J. (1986) Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking. N Engl J Med 315: 1305–1309.
33. Mikaeloff Y. Caridade G. Tardieu M. Suissa S. the KIDSEP study group. (2007) Parental smoking at home and the risk of childhood-onset multiple sclerosis in children. Brain 130: 2589–2595.
34. Montgomery S.M. Bahmanyar S. Hillert J. Ekbom A. Olsson T. (2008) Maternal smoking during pregnancy and multiple sclerosis amongst offspring. Eur J Neurol 15: 1395–1399.
35. Motz G.T. Eppert B.L. Wesselkamper S.C. Flury J.L. Borchers M.T. 2010a Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice. Am J Respir Crit Care Med 181: 1223–1233.
36. Motz G.T. Eppert B.L. Wortham B.W. Amos-Kroohs R.M. Flury J.L. Wesselkamper S.C. et al 2010b Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease. J Immunol 184: 4460–4469.
37. Nielsen T.R. Pedersen M. Rostgaard K. Frisch M. Hjalgrim H. (2007) Correlations between Epstein-Barr virus antibody levels and risk factors for multiple sclerosis in healthy individuals. Mult Scler 13: 420–423.
38. Orton S.M. Herrera B.M. Yee I.M. Valdar W. Ramagopalan S.V. Sadovnick A.D. et al (2006) Sex ratio of multiple sclerosis in Canada: a longitudinal study. Lancet Neurol 5: 932–936.
39. Pekmezovic T. Drulovic J. Milenkovic M. Jarebinski M. Stojsavljevic N. Mesaros S. et al (2006) Lifestyle factors and multiple sclerosis: a case-control study in Belgrade. Neuroepidemiology 27: 212–216.
40. Pittas F. Ponsonby A.L. van der Mei I.A. Taylor B.V. Blizzard L. Groom P. et al (2009) Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis. J Neurol 256: 577–585.
41. Prummel M.F. Wiersinga W.M. (1993) Smoking and risk of Graves' disease. JAMA 269: 479–482.
42. Riise T. Nortvedt M.W. Ascherio A. (2003) Smoking is a risk factor for multiple sclerosis. Neurology 61: 1122–1124.
43. Rodriguez Regal A. del Campo Amigo M. Paz-Esquete J. Martinez Feijoo A. Cebrian E. Suarez Gil P. et al (2009) [A case-control study of the influence of the smoking behaviour in multiple sclerosis]. Neurologia 24: 177–180.
44. Russo C. Morabito F. Luise F. Piromalli A. Battaglia L. Vinci A. et al (2008) Hyperhomocysteinemia is associated with cognitive impairment in multiple sclerosis. J Neurol 255: 64–69.
45. Sena A. Bendtzen K. Cascais M.J. Pedrosa R. Ferret-Sena V. Campos E. et al (2010) Influence of apolipoprotein E plasma levels and tobacco smoking on the induction of neutralising antibodies to interferon-beta. J Neurol 257: 1703–1707.
46. Sibley W.A. Bamford C.R. Clark K. (1985) Clinical viral infections and multiple sclerosis. Lancet 1 (8441): 1313–1315.
47. Silva K.R. Alvarenga R.M. Fernandez Y.F.O. Alvarenga H. Thuler L.C. (2009) Potential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study. Arq Neuropsiquiatr 67: 229–234.
48. Simon K.C. van der Mei I.A. Munger K.L. Ponsonby A. Dickinson J. Dwyer T. et al (2010) Combined effects of smoking, anti-EBNA antibodies, and HLA-DRB1*1501 on multiple sclerosis risk. Neurology 74: 1365–1371.
49. Simpson C.A. Newell D.J. Schapira K. (1966) Smoking and multiple sclerosis. Neurology 16: 1041–1043.
50. Simpson S. Jr Pittas F. van der Mei I. Blizzard L. Ponsonby A.L. Taylor B. (2011) Trends in the epidemiology of multiple sclerosis in Greater Hobart, Tasmania: 1951 to 2009. J Neurol Neurosurg Psychiatry 82: 180–187.
51. Sopori M.L. Kozak W. (1998) Immunomodulatory effects of cigarette smoke. J Neuroimmunol 83: 148–156.
52. Sundstrom P. Nystrom L. (2008) Smoking worsens the prognosis in multiple sclerosis. Mult Scler 14: 1031–1035.
53. Sundstrom P. Nystrom L. Hallmans G. (2008) Smoke exposure increases the risk for multiple sclerosis. Eur J Neurol 15: 579–583.
54. Thorogood M. Hannaford P.C. (1998) The influence of oral contraceptives on the risk of multiple sclerosis. Br J Obstet Gynaecol 105: 1296–1299.
55. van der Mei I.A. Simpson S. Jr Stankovich J. Taylor B.V. van der Mei I.A.F. (2011) Individual and joint action of environmental factors and risk of MS. Neurol Clin 29: 233–255.
56. Villard-Mackintosh L. Vessey M.P. (1993) Oral contraceptives and reproductive factors in multiple sclerosis incidence. Contraception 47: 161–168.
57. Wingerchuk D.M. (2011) Environmental factors in multiple sclerosis: Epstein-Barr virus, vitamin D, and cigarette smoking. Mt Sinai J Med 78: 221–230.
58. World Health Organization Tobacco Free Initiative (2002 a) Cigarette consumption. http://www.who.int/tobacco/en/atlas8.pdf. Accessed 13 August 2011.
59. World Health Organization Tobacco Free Initiative (2002 b) Female smoking. http://www.who.int/tobacco/en/atlas6.pdf. Accessed 13 August 2011.