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Volumn 32, Issue 2, 2012, Pages 109-114

MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis

Author keywords

MTHFR A1298C; MTHFR C677T; OPG A163G; osteoporosis; polymorphisms; rheumatoid arthritis

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); OSTEOPROTEGERIN;

EID: 84858190702     PISSN: 02780240     EISSN: 18758630     Source Type: Journal    
DOI: 10.3233/DMA-2011-0868     Document Type: Article
Times cited : (20)

References (34)
  • 1
    • 0042807404 scopus 로고    scopus 로고
    • A common methylenetetrahydrofolate reductase (C677T) polymorphism is associated with low bone mineral density and increased fracture incidence after menopause: Longitudinal data from the Danish osteoporosis prevention study
    • B. Abrahamsen, J.S. Madsen, C.L. Tofteng, L. Stilgren, E.M. Bladbjerg, S.R. Kristensen, K. Brixen and L. Mosekilde, A common methylenetetrahydrofolate reductase (C677T) polymorphism is associated with low bone mineral density and increased fracture incidence after menopause: longitudinal data from the Danish osteoporosis prevention study, J Bone Miner Res 18 (2003), 723-729. (Pubitemid 36899322)
    • (2003) Journal of Bone and Mineral Research , vol.18 , Issue.4 , pp. 723-729
    • Abrahamsen, B.1    Madsen, J.S.2    Tofteng, C.L.3    Stilgren, L.4    Bladbjerg, E.M.5    Kristensen, S.R.6    Brixen, K.7    Mosekilde, L.8
  • 2
    • 15544384276 scopus 로고    scopus 로고
    • Are effects of MTHFR (C677T) genotype on BMD confined to women with low folate and riboflavin intake? Analysis of food records from the Danish osteoporosis prevention study
    • DOI 10.1016/j.bone.2004.12.014
    • B. Abrahamsen, J.S. Madsen, C.L. Tofteng, L. Stilgren, E.M. Bladbjerg, S.R. Kristensen, K. Brixen and L. Mosekilde, Are effects of MTHFR (C677T) genotype on BMD confined to women with low folate and riboflavin intake? Analysis of food records from the Danish osteoporosis prevention study, Bone 36 (2005), 577-583. (Pubitemid 40403857)
    • (2005) Bone , vol.36 , Issue.3 , pp. 577-583
    • Abrahamsen, B.1    Madsen, J.S.2    Tofteng, C.L.3    Stilgren, L.4    Bladbjerg, E.M.5    Kristensen, S.R.6    Brixen, K.7    Mosekilde, L.8
  • 5
    • 0036736816 scopus 로고    scopus 로고
    • Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis
    • B. Arko, J. Prezelj, R. Komel, A. Kocijancic, P. Hudler and J. Marc, Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis, J Clin Endocrinol Metab 87 (2002), 4080-4084.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4080-4084
    • Arko, B.1    Prezelj, J.2    Komel, R.3    Kocijancic, A.4    Hudler, P.5    Marc, J.6
  • 6
    • 33846593344 scopus 로고    scopus 로고
    • 6 with bone mineral density in postmenopausal British women
    • DOI 10.1016/j.bone.2006.10.008, PII S8756328206007472
    • M. Baines, M.B. Kredan, J. Usher, A. Davison, G. Higgins, W. Taylor, C. West, W.D. Fraser and L.R. Ranganath, The association of homocysteine and its determinants MTHFR genotype, folate, vitamin B12 and vitamin B6 with bone mineral density in postmenopausal British women, Bone 40 (2007), 730-736. (Pubitemid 46187220)
    • (2007) Bone , vol.40 , Issue.3 , pp. 730-736
    • Baines, M.1    Kredan, M.-B.2    Usher, J.3    Davison, A.4    Higgins, G.5    Taylor, W.6    West, C.7    Fraser, W.D.8    Ranganath, L.R.9
  • 7
    • 72949104886 scopus 로고    scopus 로고
    • Dahlqvist, atherothrombotic events in rheumatoid arthritis are predicted by homocysteine-A six-Year follow-Up study
    • S. Berglund, A. Södergren, S. Wållberg Jonsson and S. Rantapää, Dahlqvist, Atherothrombotic events in rheumatoid arthritis are predicted by homocysteine-a six-year follow-up study, Clin Exp Rheumatol 27 (2009), 822-825.
    • (2009) Clin Exp Rheumatol , vol.27 , pp. 822-825
    • Berglund, S.1    Södergren, A.2    Wållberg Jonsson, S.3    Rantapää, S.4
  • 8
    • 2942700001 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase (MTHFR) 677C→T and 1298A→C mutations are associated with DNA hypomethylation
    • R. Castro, I. Rivera, P. Ravasco, M.E. Camilo, C. Jakobs and H.J. Blom, ITJ de Almeida, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C->T and 1298A->C mutations are associated with DNAhypomethylation, Med Genet 41 (2004), 454-458. (Pubitemid 38788042)
    • (2004) Journal of Medical Genetics , vol.41 , Issue.6 , pp. 454-458
    • Castro, R.1    Rivera, I.2    Ravasco, P.3    Camilo, M.E.4    Jakobs, C.5    Blom, H.J.6    De Almeida, I.T.7
  • 10
    • 66149144789 scopus 로고    scopus 로고
    • Plasma total homocys-teine level and methylenetetrahydrofolate reductase 677c>t genetic polymorphism in japanese patients with rheumatoid arthritis
    • C. Fujimaki, H. Hayashi, S. Tsuboi, T. Matsuyama, K. Ko-suge, H. Yamada, K. Inoue and K. Itoh, Plasma total homocys-teine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis, Biomarkers 14 (2009), 49-54.
    • (2009) Biomarkers , vol.14 , pp. 49-54
    • Fujimaki, C.1    Hayashi, H.2    Tsuboi, S.3    Matsuyama, T.4    Ko-Suge, K.5    Yamada, H.6    Inoue, K.7    Itoh, K.8
  • 13
    • 4344608282 scopus 로고    scopus 로고
    • Association of plasma folate, plasma total homocysteine, but not methylenetetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: A cross-sectional study
    • DOI 10.1016/j.bone.2004.04.018, PII S8756328204001772
    • J. Golbahar, A. Hamidi, M.A. Aminzadeh and G.R. Om-rani, Association of plasma folate, plasma total homocysteine, but not methylenetetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: a cross-sectional study, Bone 35 (2004), 760-765. (Pubitemid 39141877)
    • (2004) Bone , vol.35 , Issue.3 , pp. 760-765
    • Golbahar, J.1    Hamidi, A.2    Aminzadeh, M.A.3    Omrani, G.R.4
  • 14
    • 33846577275 scopus 로고    scopus 로고
    • Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women
    • DOI 10.1016/j.bone.2006.09.031, PII S8756328206007381
    • X. Hong, Y.H. Hsu, H. Terwedow, G. Tang, X. Liu, S. Jiang, X. Xu and X. Xu, Association of the methylenetetrahydrofolate reductase C677T polymorphism and fracture risk in Chinese postmenopausal women, Bone 40 (2007), 737-742. (Pubitemid 46187215)
    • (2007) Bone , vol.40 , Issue.3 , pp. 737-742
    • Hong, X.1    Hsu, Y.-H.2    Terwedow, H.3    Tang, G.4    Liu, X.5    Jiang, S.6    Xu, X.7    Xu, X.8
  • 15
    • 29244488577 scopus 로고    scopus 로고
    • Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men
    • DOI 10.1007/s00439-005-0062-4
    • Y.H. Hsu, T. Niu, H.A. Terwedow, X. Xu, Y. Feng, Z. Li, J.D. Brain, C.J. Rosen, N. Laird and X. Xu, Variation in genes involved in the RANKL/RANK/OPG bone remodeling pathway are associated with bone mineral density at different skeletal sites in men, Hum Genet 118 (2006), 568-577. (Pubitemid 41825129)
    • (2006) Human Genetics , vol.118 , Issue.5 , pp. 568-577
    • Hsu, Y.-H.1    Niu, T.2    Terwedow, H.A.3    Xu, X.4    Feng, Y.5    Li, Z.6    Brain, J.D.7    Rosen, C.J.8    Laird, N.9    Xu, X.10
  • 16
    • 33746636881 scopus 로고    scopus 로고
    • Homocysteine enhances apoptosis in human bone marrow stromal cells
    • DOI 10.1016/j.bone.2006.03.004, PII S8756328206003735
    • D.J. Kim, J.M. Koh, O. Lee, N.J. Kim, Y.S. Lee, Y.S. Kim, J.Y. Park and K.U. Lee, Kim GS, Homocysteine enhances apop-tosis in human bone marrow stromal cells, Bone 39 (2006), 582-590. (Pubitemid 44149276)
    • (2006) Bone , vol.39 , Issue.3 , pp. 582-590
    • Kim, D.J.1    Koh, J.-M.2    Lee, O.3    Kim, N.J.4    Lee, Y.-S.5    Kim, Y.S.6    Park, J.-Y.7    Lee, K.-U.8    Kim, G.S.9
  • 17
    • 34948883973 scopus 로고    scopus 로고
    • Association between osteoprotegerin (OPG), receptor activator of nuclear factor-κB (RANK), and RANK ligand (RANKL) gene polymorphisms and circulating OPG, soluble RANKL levels, and bone mineral density in Korean postmenopausal women
    • DOI 10.1097/gme.0b013e31802d976f
    • J.G. Kim, J.H. Kim, J.Y. Kim, S.Y. Ku, B.C. Jee, C.S. Suh, S.H. Kim and Y.M. Choi, Association between osteoprotegerin (OPG), receptor activator of nuclear factor-kappaB (RANK), and RANK ligand (RANKL) gene polymorphisms and circulating OPG, soluble RANKL levels, and bone mineral density in Korean postmenopausal women, Menopause 14 (2007), 913-918. (Pubitemid 47517592)
    • (2007) Menopause , vol.14 , Issue.5 , pp. 913-918
    • Kim, J.G.1    Kim, J.H.2    Kim, J.Y.3    Ku, S.Y.4    Jee, B.C.5    Suh, C.S.6    Kim, S.H.7    Choi, Y.M.8
  • 19
    • 33745497498 scopus 로고    scopus 로고
    • Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation
    • DOI 10.1359/jbmr.060406
    • J.M. Koh, Y.S. Lee, Y.S. Kim, D.J. Kim, H.H. Kim, J.Y. Park, K.U. Lee and G.S. Kim, Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation, J Bone Miner Res 21 (2006), 1003-1011. (Pubitemid 43962829)
    • (2006) Journal of Bone and Mineral Research , vol.21 , Issue.7 , pp. 1003-1011
    • Koh, J.-M.1    Lee, Y.-S.2    Kim, Y.S.3    Kim, D.J.4    Kim, H.-H.5    Park, J.-Y.6    Lee, K.-U.7    Kim, G.S.8
  • 22
    • 13944266746 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism (MTHFR C677T) and bone mineral density in Chinese men and women
    • DOI 10.1016/j.bone.2004.09.008
    • M. Li, E.M. Lau and J. Woo, Methylenetetrahydrofolate re-ductase polymorphism (MTHFR C677T) and bone mineral density in Chinese men and women, Bone 35 (2004), 1369-1374. (Pubitemid 40267636)
    • (2004) Bone , vol.35 , Issue.6 , pp. 1369-1374
    • Li, M.1    Lau, E.M.C.2    Woo, J.3
  • 24
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • S.A. Miller, D.D. Dykes and H.P. Polesky, A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic acid res 16 (1988), 1215.
    • (1988) Nucleic Acid Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.P.3
  • 25
    • 0033953774 scopus 로고    scopus 로고
    • Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women
    • DOI 10.1007/s002230010038
    • M. Miyao, H. Morita, T. Hosoi, H. Kurihara, S. Inoue, S. Hoshino, M. Shiraki, Y. Yazaki and Y. Ouchi, Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women, Calcif Tissue Int 66 (2000), 190-194. (Pubitemid 30091759)
    • (2000) Calcified Tissue International , vol.66 , Issue.3 , pp. 190-194
    • Miyao, M.1    Morita, H.2    Hosoi, T.3    Kurihara, H.4    Inoue, S.5    Hoshino, S.6    Shiraki, M.7    Yazaki, Y.8    Ouchi, Y.9
  • 26
    • 0035810980 scopus 로고    scopus 로고
    • Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells implications for vascular disease
    • R. Poddar, N. Sivasubramanian, P.M. DiBello, K. Robinson and D.W. Jacobsen, Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease, Circulation 103 (2001), 2717-2723. (Pubitemid 32538788)
    • (2001) Circulation , vol.103 , Issue.22 , pp. 2717-2723
    • Poddar, R.1    Sivasubramanian, N.2    DiBello, P.M.3    Robinson, K.4    Jacobsen, D.W.5
  • 27
    • 5444220704 scopus 로고    scopus 로고
    • High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells
    • DOI 10.1016/j.atherosclerosis.2004.06.015, PII S0021915004003399
    • B. Raposo, C. Rodŕiguez, J. Mart'inez-Gonzalez and L. Badi-mon, High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells, Atherosclerosis 177 (2004), 1-8. (Pubitemid 39361132)
    • (2004) Atherosclerosis , vol.177 , Issue.1 , pp. 1-8
    • Raposo, B.1    Rodriguez, C.2    Martinez-Gonzalez, J.3    Badimon, L.4
  • 28
    • 33751536723 scopus 로고    scopus 로고
    • No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly australian women
    • T. Ueland, J. Bollerslev, S.G. Wilson, I.M. Dick, F.M. Islam, B.H. Mullin, A. Devine and R.L. Prince, No associations between OPG gene polymorphisms or serum levels and measures of osteoporosis in elderly Australian women, Bone 40 (2007), 175-178.
    • (2007) Bone , vol.40 , pp. 175-178
    • Ueland, T.1    Bollerslev, J.2    Wilson, S.G.3    Dick, I.M.4    Islam, F.M.5    Mullin, B.H.6    Devine, A.7    Prince, R.L.8
  • 31
    • 0036252140 scopus 로고    scopus 로고
    • Activation of the immune system and inflammatory activity in relation to markers of atherothrombotic disease and atherosclerosis in rheumatoid arthritis
    • S. Wållberg-Jonsson, J.T. Cvetkovic, K.G. Sundqvist, A.K. Lefvert and S. Rantapää-Dahlqvist, Activation of the immune system and inflammatory activity in relation to markers of atherothrombotic disease and atherosclerosis in rheumatoid arthritis, J Rheumatol 29 (2002), 875-882. (Pubitemid 34493486)
    • (2002) Journal of Rheumatology , vol.29 , Issue.5 , pp. 875-882
    • Wallberg-Jonsson, S.1    Cvetkovic, J.T.2    Sundqvist, K.-G.3    Lefvert, A.K.4    Rantapaa-Dahlqvist, S.5
  • 32
    • 39649105655 scopus 로고    scopus 로고
    • Elevated Plasma Homocysteine and Low Vitamin B-6 Status in NonSUPPLementing Older Women with Rheumatoid Arthritis
    • DOI 10.1016/j.jada.2007.12.001, PII S000282230702202X
    • K. Woolf and M.M. Manore, Elevated plasma homocysteine and low vitamin B-6 status in nonSUPPLementing older women with rheumatoid arthritis, J Am Diet Assoc 108 (2008), 443-453. (Pubitemid 351288615)
    • (2008) Journal of the American Dietetic Association , vol.108 , Issue.3 , pp. 443-453
    • Woolf, K.1    Manore, M.M.2
  • 33
    • 0035808458 scopus 로고    scopus 로고
    • Tumor necrosis factor-α (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways
    • DOI 10.1074/jbc.M008198200
    • Y.H. Zhang, A. Heulsmann, M.M. Tondravi, A. Mukherjee and Y. Abu-Amer, Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways, J Biol Chem 276 (2001), 563-568. (Pubitemid 32050352)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.1 , pp. 563-568
    • Zhang, Y.-H.1    Heulsmann, A.2    Tondravi, M.M.3    Mukherjee, A.4    Abu-Amer, Y.5
  • 34
    • 67349113543 scopus 로고    scopus 로고
    • The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women
    • K. Zhu, J. Beilby, I.M. Dick, A. Devine, M. Soós and R.L. Prince, The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women, Osteoporos Int 20 (2009), 1183-1191.
    • (2009) Osteoporos Int , vol.20 , pp. 1183-1191
    • Zhu, K.1    Beilby, J.2    Dick, I.M.3    Devine, A.4    Soós, M.5    Prince, R.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.