Insights into the mechanistic pathway of the Pantoea agglomerans phenylalanine aminomutase

Angewandte Chemie - International Edition

Volumn 51, Issue 12, 2012, Pages 2898-2902

  Strom, Susan ^a   Wanninayake, Udayanga ^a   Ratnayake, Nishanka Dilini ^a   Walker, Kevin D ^a,b   Geiger, James H ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

Author keywords

aminomutases; enzymes; phenylalanine; structure elucidation; X ray diffraction

Indexed keywords

AMINOMUTASES; MECHANISTIC PATHWAYS; MONODENTATES; PANTOEA AGGLOMERANS; PHENYLALANINE; SALT BRIDGES; STERIC BULK; STRUCTURE ELUCIDATION;

ENZYMES; X RAY DIFFRACTION;

AMINO ACIDS;

4 METHYLIDENEIMIDAZOLE 5 ONE; 4-METHYLIDENEIMIDAZOLE-5-ONE; AMINOTRANSFERASE; IMIDAZOLE DERIVATIVE; PHENYLALANINE; PHENYLALANINE AMINOTRANSFERASE;

ARTICLE; BINDING SITE; BIOCATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM; PANTOEA; PROTEIN DATABASE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DATABASES, PROTEIN; IMIDAZOLES; PANTOEA; PHENYLALANINE; SUBSTRATE SPECIFICITY; TRANSAMINASES;

EID: 84858177898     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201108525     Document Type: Article

References (30)

1. M. Jin, M. A. Fischbach, J. Clardy, J. Am. Chem. Soc. 2006, 128, 10660.
2. P. D. Fortin, C. T. Walsh, N. A. Magarvey, Nature 2007, 448, 824.
3. L. Feng, U. Wanninayake, S. Strom, J. Geiger, K. D. Walker, Biochemistry 2011, 50, 2919.
4. C. V. Christianson, T. J. Montavon, S. G. Van Lanen, B. Shen, S. D. Bruner, Biochemistry 2007, 46, 7205.
5. D. Krug, R. Mueller, ChemBioChem 2009, 10, 741.
6. M. J. MacDonald, G. B. D'Cunha, Biochem. Cell Biol. 2007, 85, 273.
7. J. A. Kyndt, T. E. Meyer, M. A. Cusanovich, J. J. Van Beeumen, FEBS Lett. 2002, 512, 240.
8. M. Baedeker, G. E. Schulz, Eur. J. Biochem. 2002, 269, 1790.
9. H. A. Cooke, S. D. Bruner, Biopolymers 2010, 93, 802.
10. K. R. Hanson, E. A. Havir, Arch. Biochem. Biophys. 1970, 141, 1.
11. J. C. Calabrese, D. B. Jordan, A. Boodhoo, S. Sariaslani, T. Vannelli, Biochemistry 2004, 43, 11403.
12. C. V. Christianson, T. J. Montavon, G. M. Festin, H. A. Cooke, B. Shen, S. D. Bruner, J. Am. Chem. Soc. 2007, 129, 15744.
13. B. Schuster, J. Retey, Proc. Natl. Acad. Sci. USA 1995, 92, 8433.
14. L. Poppe, J. Retey, Angew. Chem. 2005, 117, 3734
15. Angew. Chem. Int. Ed. 2005, 44, 3668.
16. S. Bartsch, U. T. Bornscheuer, Angew. Chem. 2009, 121, 3412
17. Angew. Chem. Int. Ed. 2009, 48, 3362.
18. T. F. Schwede, J. Rétey, G. E. Schulz, Biochemistry 1999, 38, 5355.
19. G. V. Louie, M. E. Bowman, M. C. Moffitt, T. J. Baiga, B. S. Moore, J. P. Noel, Chem. Biol. 2006, 13, 1327.
20. T. J. Montavon, C. V. Christianson, G. M. Festin, B. Shen, S. D. Bruner, Bioorg. Med. Chem. Lett. 2008, 18, 3099.
21. H. Ritter, G. E. Schulz, Plant Cell 2004, 16, 3426.
22. K. D. Dunkley, T. R. Callaway, V. I. Chalova, R. C. Anderson, M. M. Kundinger, C. S. Dunkley, D. J. Nisbet, S. C. Ricke, Anaerobe 2008, 14, 35.
23. N. J. Turner, Curr. Opin. Chem. Biol. 2011, 15, 234.
24. N. D. Ratnayake, U. Wanninayake, J. H. Geiger, K. D. Walker, J. Am. Chem. Soc. 2011, 133, 8531.
25. E. W. Sayers, T. Barrett, D. A. Benson, S. H. Bryant, K. Canese, V. Chetvernin, D. M. Church, M. DiCuccio, R. Edgar, S. M. Federhen, Nucleic Acids Res. 2009, 37, D 5.
26. M. C. Moffitt, G. V. Louie, M. E. Bowman, J. Pence, J. P. Noel, B. S. Moore, Biochemistry 2007, 46, 1004.
27. L. K. Xiang, B. S. Moore, J. Biol. Chem. 2002, 277, 32505.
28. L. K. Xiang, B. S. Moore, J. Bacteriol. 2005, 187, 4286.
29. T. Grecu, Masters of Philosophy Thesis, University of Manchester (UK), 2010.
30. J. M. Oclarit, H. Okada, S. Ohta, K. Kaminura, Y. Yamaoka, T. Iizuka, S. Miyashiro, S. Ikegami, Microbios 1994, 78, 7.